Clinical trials: Middle Aged
Fall Risk in Middle-Aged and Older Adults
Short-term Changes in Postural Sway, Gait, and fNIRS-derived Cortical Metrics After a 4-week AI-assisted Exercise Program: a Single-arm Pre-post Study
This single-arm pre-post study will enroll 50 participants aged 52-65 years who will undergo a 4-week AI-assisted exercise intervention.
- Trial name
- NCT07876011
- Testing
- AI-assited exercise
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Middle Aged
A Text- and Audio-based Intervention to Promote Physical Activity in Midlife
This is a randomized, controlled pilot trial (N=30) to examine the feasibility, acceptability, and preliminary efficacy of the Move with Meaning program, an 8- week, text message- and audio-based intervention to promote physical…
- Trial name
- NCT06172933
- Testing
- Move with Meaning
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Intentionality the Matrix of Healing, Community
Oral Health Education for Older Adults: Intentionality in Action
After obtaining approval from the Institutional Review Board (IRB), the clinical trial will be registered on a designated trial registration website. Participant recruitment will be conducted online.
- Conditions
- Intentionality the Matrix of Healing, Community, Middle-aged and Older Adults, Oral Health Education
- Trial name
- NCT07265726
- Testing
- Intentional Interview, Expressive Arts Activities
- Where
- Taiwan
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Mackay Memorial Hospital
Healthy Middle-aged Subjects, Obesity & Overweight
Stearic Acid and Endothelial Function
The goal of this clinical trial is to evaluate the postprandial and long-term effects of dietary stearic acid on vascular function in overweight or obese adult males and females aged 40-70 years.
- Trial name
- NCT07831603
- Testing
- High Palmitic Acid Diet, Stearic Acid Test Meal, Oleic Acid Test Meal
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Florida State University
Body Image, Mindfulness Based Stress Reduction
MBSR Effects on Aging Anxiety and Body Image
This study was designed to determine the effect of a mindfulness-based stress reduction (MBSR) program on aging anxiety and body image among middle-aged women.
- Conditions
- Body Image, Mindfulness Based Stress Reduction, Middle Aged
- Trial name
- NCT07344896
- Testing
- bilinçli farkındalık temelli stres azaltma programı
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- KTO Karatay University
Healthy Aging, Middle-aged and Older Adults
Peanut Butter and Brain Health
Healthy foods, including peanuts, may improve brain function, which is essential for cognitive and metabolic health, and may contribute to improved food intake regulation.
- Trial name
- NCT07774546
- Testing
- Peanut butter
- Where
- Netherlands
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Penn State University
Healthy Volunteers (Middle-aged Smokers)
Effects of Curcumin on Vascular Reactivity
The aim of this study is to determine if an oral loading-dose of curcumin can improve vascular endothelium reactivity in patients with moderate cardiovascular risk
- Trial name
- CURCUMIN (NCT01543386)
- Testing
- Curcumin
- Where
- France
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Abdominal Obesity, Abdominal Obesity-Metabolic Syndrome
Metabolic Effectiveness of Extracorporeal Shockwave on Abdominal Adiposity
Egyptian Ministry of Health and Population's Preventive Sector, have named obesity as one of the top contributors to the national mortality and morbidity.
- Conditions
- Abdominal Obesity, Abdominal Obesity-Metabolic Syndrome, Abdominal Obesity in Young and Middle Aged Adults
- Trial name
- NCT07686601
- Testing
- conventional balanced, low-calorie diet 1500 k/cal for 12 weeks, aerobic training program, extracorporeal shockwave therapy
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cairo University
Health Literacy, Middle Aged
Health Literacy-Based Multifactorial Program for Adults With Sarcopenia
Sarcopenia is a common age-related condition characterized by the progressive loss of muscle mass and function, which may lead to reduced physical performance, disability, and poorer quality of life.
- Conditions
- Health Literacy, Middle Aged, Elderly (People Aged 65 or More), Exercise Therapy
- Trial name
- NCT07654478
- Testing
- Multicomponent Intervention
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University Hospital
Middle-aged Adults, Major Depressive Disorder
Daily Stress and Vascular Function in Midlife as a Risk Factor for Cognitive Decline
The goal of this pilot clinical trial is to begin to understand how day-to-day stress affects cardiovascular health and brain function in middle-aged adults.
- Trial name
- NCT06466655
- Testing
- MitoTempol, Lactated Ringer's (control)
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Mild Cognitive Impairment in Middle-aged Adults
Deafness and Cognition in Middle-aged Adults
A mild cognitive impairment was observed in 50% of cochlear implant candidates aged 65 years and over, compared to 5-19% in general population. No studies analysed cognition in patients younger than 65 years.
- Trial name
- SURDICOG (NCT05149742)
- Testing
- Cognitive and audiometry evaluation
- Where
- France
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Sedentary Middle Age and Older Aged Adults
Improving Exercise Adherence With App Technology for At-Risk Adults Living in Rural Kansas and Nebraska
Alzheimer's disease and related dementias are a public health crisis impacting individuals across the world. In the United States, adults living in rural areas face an elevated risk for cognitive impairment mainly due to…
- Trial name
- RemoteEx+ (NCT07171255)
- Testing
- RemoteEx+ Programming
- Where
- 2 sites in United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Creighton University
Abdominal Obesity in Young and Middle Aged Adults, Gluteal Muscles Strength and Endurance
The Association Between Abdominal Obesity, Gluteal Muscles Strength and Endurance in Young and Middle-aged Adults.
to investigate association between abdominal obesity, gluteal muscles strength and endurance in young and middle-aged adults.
- Trial name
- NCT07022691
- Testing
- Lafayette dynamometer:
- Where
- Egypt
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Cairo University
Middle Aged, Women
Web-app Based Lifestyle Physical Activity Promotion Program (WPAPP) for Middle Aged Latinas
The purpose of the proposed project is to conduct a pilot randomized controlled trial (RCT) of the Web-App based Lifestyle Physical Activity Promotion Program (WPAPP) for middle-aged Latinas.
- Conditions
- Middle Aged, Women, Depressive Symptoms, Physical Activity
- Trial name
- WPAPP-Latina (NCT06768801)
- Testing
- WPAPP-Latina
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Endothelial Function, Aerobic Exercise
VascuFit: Exercise and Vascular Aging
Exercise is a cornerstone of health care helping to improve and maintain a good organ functionality, including vascular function, in health and disease.
- Conditions
- Endothelial Function, Aerobic Exercise, Middle-aged Adults Sedentary, Elevated CV-risk)
- Trial name
- VascuFit (NCT05235958)
- Testing
- non-linear periodized exercise (NLPE), Exercise counselling
- Where
- Switzerland
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Karsten Königstein
Exercise, Gait
Rhythmically Entrained Exercise in Community-Dwelling Older Adults
Researchers at the University of North Carolina at Greensboro conduct a single-arm intervention trial to investigate the efficacy of a music-based group exercise program for community-dwelling older adults.
- Conditions
- Exercise, Gait, Cognitive Decline, Caregiver Burden
- Trial name
- REECO (NCT05462977)
- Testing
- Group exercise program
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Greensboro
Cardiometabolic Disease, Health Coaching
A Feasibility Study of a Health Coaching Programme for Middle-aged Adults With Cardiometabolic Risk
Cardiometabolic disease has been an increasing trend globally and remains the major cause of morbidity and mortality. Health coaching, a process of goal-oriented and client-centered partnership that is health-focus and through…
- Conditions
- Cardiometabolic Disease, Health Coaching, Middle-aged Adults, Primary Prevention
- Trial name
- NCT05444140
- Testing
- Health coaching
- Where
- Hong Kong
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Women's Health, Hybrid Training
Hybrid Training and Middle Age
Modern living and physical inactivity results in many ailments, including obesity, non-alcoholic fatty liver disease (NAFLD), and inflammatory issues.
- Conditions
- Women's Health, Hybrid Training, Middle Aged, Non-alcoholic Fatty Liver Disease
- Trial name
- NCT05231564
- Testing
- hybrid training
- Where
- Iran
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Sistan and Baluchestan
Middle Aged Patients
Effect of Intranasal Insulin on Postoperative Cognitive Dysfunction
Our study is designed to evaluate the effect of intranasal insulin on postoperative cognitive dysfunction. Primary outcome: 1. The occurrence of cognitive dysfunction at approximately 7 days after surgery. Secondary outcome: 1.
- Trial name
- NCT04154449
- Testing
- Intranasal insulin
- Where
- 2 sites in Egypt
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Minia University