Clinical trials: Middle-aged and Older Adults
Healthy, Physical Examination
Walking Aid Assessment, Arm Strength and Force Under the Foot in Normal Subjects
This study will collect biomedical performance data on walking characteristics in normal, healthy people when walking with walking aids and when walking unaided.
- Conditions
- Healthy, Physical Examination, Middle Age, Aged
- Trial name
- NCT05092932
- Testing
- Normal Foot Force
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Saskatchewan
Metabolic Syndrome
Effects of Yoga on Metabolic Syndrome
Metabolic syndrome (MetS) is a clustering of cardiovascular risk factors characterizing central obesity, insulin resistance, dyslipidemia and high blood pressure.
- Trial name
- NCT02140203
- Testing
- Yoga Training
- Where
- China
- Volunteers
- 182 people
- Sponsor
- Angus Yu
Sleep, Metabolic Syndrome
Extending Sleep to Reverse Metabolic Syndrome in Middle-aged Adults: Acceptability and Feasibility of a Sleep Intervention
This pilot study will test acceptability and feasibility of a sleep extension intervention in community dwelling, short sleeping, racially/ethnically diverse middle aged adults with Metabolic Syndrome (METs).
- Trial name
- NCT03599388
- Testing
- Self- management for adequate sleep intervention (SASI)
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- NYU Langone Health
Knee Osteoarthritis
Self-administered Acupressure for Knee Osteoarthritis in Middle- and Older-Aged Adults
This is a randomized controlled trial comparing the short-term and medium-term effect of self-administered and knee health education for relieving knee pain in middle-aged and older adults with knee osteoarthritis.
- Trial name
- NCT04191837
- Testing
- Self-administered acupressure treatment group, Knee health education control group
- Where
- Hong Kong
- Volunteers
- 314 people
- Sponsor
- The Hong Kong Polytechnic University
Healthy
Effects of Milk Powder Intervention on Body Composition and Physical Performance in Middle-aged and Older Adults
This study aims to conduct a 24-week intervention involving formula milk powder for middle-aged and elderly individuals, assessing its impact on body composition and physical performance in comparison to interventions using…
- Trial name
- NCT06429410
- Testing
- fortified formula milk powder, formula milk powder, regular milk powder
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Huilian Zhu
Human Immunodeficiency Virus, Hypogonadism, Male
Gonadal Function in Young to Middle Aged HIV-infected Men
HIV infection is associated to premature decline of serum testosterone. However, prevalence and biochemical characterization of hypogonadism in HIV-infected men are still to be well defined.
- Conditions
- Human Immunodeficiency Virus, Hypogonadism, Male, Erectile Dysfunction
- Trial name
- NCT03747003
- Testing
- No intervention is provided
- Where
- Italy
- Volunteers
- 315 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Modena
Body Temperature Changes, Heat Stress
Progressive Heat Exposure and Physiological Strain
Occupational heat-stress guidelines are commonly based on the level of environmental heat exposure and are largely derived from studies conducted under constant environmental conditions.
- Conditions
- Body Temperature Changes, Heat Stress, Heat Exposure, Heat Fatigue
- Trial name
- NCT07847437
- Testing
- Constant Heat Exposure, Progressively Increasing Heat Exposure
- Where
- Canada
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Endothelial Dysfunction, Aging
Effects of Aronia Berries on Vascular Endothelial Function and the Gut Microbiota in Middle-Aged/Older Adults
Aging is the primary risk factor for cardiovascular disease (CVD) largely due to vascular endothelial dysfunction, a major initial step in the development of atherosclerosis.
- Trial name
- NCT03824041
- Testing
- Aronia full spectrum - half dose, Aronia full spectrum - full dose
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Cervical Pain, Posterior, Swallowing Difficulties
Tongue Pressure in Middle-Aged and Elderly Individuals With Chronic Cervical Pain
The goal of the cross-sectional study is to explore the impact of neck pain on tongue pressure in the middle-aged and elderly population and analyze the effects of different cranio-cervical positioning on tongue pressure…
- Conditions
- Cervical Pain, Posterior, Swallowing Difficulties, Swallowing Disorders
- Trial name
- NCT07021586
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Obesity
Telenutrition Center: Examining the Implementation of Behavioral Therapy for Obesity
The Telenutrition Center will use the Reach, Effectiveness, Adoption, Implementation and Maintenance (RE-AIM) Framework to assess the implementation of an evidence-based, intensive behavior therapy (IBT) for obesity intervention…
- Trial name
- NCT03855566
- Testing
- Intensive behavioral therapy for obesity
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Southern Mississippi
Type 1 Diabetes, Latent Autoimmune Diabetes in Adults
Digital Exercise for Middle-Aged Adults With Type 1 Diabetes and Other Absolute Insulin Deficiency Diabetes
The challenges of living with type 1 diabetes often stand in the way of getting enough exercise. Continuous blood sugar monitoring has revolutionized type 1 diabetes care but remains underutilized to sustainably support exercise…
- Conditions
- Type 1 Diabetes, Latent Autoimmune Diabetes in Adults, Pancreatitis
- Trial name
- NCT06098729
- Testing
- Digital Exercise
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Yale University
Stroke, Stroke (6 Months or More After Onset)
Co-Designed Digital Education and Peer Support for Young and Middle-Aged Stroke Survivors
Stroke survivors often experience persistent unmet needs during long-term recovery. Young and middle-aged stroke survivors may face additional challenges in balancing rehabilitation with work and family responsibilities.
- Trial name
- NCT07725666
- Testing
- Patient-Centered Digital Education and Peer Support Program, Usual Post-Stroke Care
- Volunteers
- 148 people
- Sponsor
- Chang Gung Memorial Hospital
Type 2 Diabetes Mellitus (T2DM)
Effects of a Multimodal Exercise Program on Physical Performance and Muscle Function in Middle-aged Patients With T2DM
Background Middle-aged adults with type 2 diabetes mellitus (T2DM), especially in Asian populations, are at increased risk of sarcopenia, reduced muscle function, and decline in physical performance.
- Trial name
- NCT07255222
- Testing
- A Multimodal Exercise Intervention
- Where
- Taiwan
- Volunteers
- 66 people
- Sponsor
- Chung Shan Medical University
Aging, Parkinson's Disease (PD)
Impact of Force Control of Hip Abductor Muscles in Healthy Adults and Individuals With Parkinson's Disease
Both aging and Parkinson's disease (PD) negatively affect postural control and increase the risk of falls, with frontal plane balance being particularly challenging for these populations.
- Trial name
- NCT07568951
- Testing
- Age, Parkinson's disease (PD)
- Where
- 2 sites in Taiwan
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Vascular Stiffness, Vasodilation
Effects of Betalains on Cardiovascular Health and Quality of Life
The goal of this randomized, double-blind, placebo-controlled, cross-over trial is to investigate the effects of beetroot-derived betalains on cardiovascular health, sleep and quality of life in healthy middle-aged individuals.
- Conditions
- Vascular Stiffness, Vasodilation, Sleep, Quality of Life
- Trial name
- NCT06117007
- Testing
- Betalains
- Where
- United Kingdom
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- King's College London
Hypertension, Cardiovascular Risk
Multicomponent Exercise Program in Women With Hypertension
This study tested whether a 12-week supervised multicomponent exercise program is associated with changes in blood pressure, estimated cardiorespiratory fitness, handgrip strength and health-related quality of life in women aged…
- Trial name
- NCT07913971
- Testing
- Multicomponent exercise program
- Where
- Colombia
- Volunteers
- 32 people
- Sponsor
- Universidad Pedagogica Nacional, Colombia
Aging, Sedentary Behavior
Impact of Cocoa Flavanols on Pulmonary Oxygen Uptake Kinetics and Exercise Tolerance in Sedentary Middle-aged Adults
In recent years, there has been significant interest in dietary flavonoids (biologically active plant-derived compounds) as potential therapeutics.
- Trial name
- NCT04370353
- Testing
- Cocoa flavanols
- Where
- United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Liverpool John Moores University
Obesity
Protect - The Impact of a High Protein Diet on Preservation of Muscle Mass
The present study is designed to investigate whether a high protein diet will preserve muscle mass during caloric restriction in older adults.
- Trial name
- NCT01915030
- Testing
- High protein diet, standard protein diet
- Where
- Netherlands
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Knee Osteoarthritis
Self-administered Acupressure for Knee Osteoarthritis: A Pilot Randomized Controlled Trial
Objectives: To test the feasibility of the study design and clinical effects of self-administered acupressure on relieving knee osteoarthritis (OA) pain.
- Trial name
- NCT03155737
- Testing
- Self-acupressure, Knee health education
- Where
- Hong Kong
- Volunteers
- 35 people
- Sponsor
- The Hong Kong Polytechnic University
Self Esteem, Physical Activity
Exploring Temporal Relationships Between Self-worth and Physical Activity Middle-aged Women
The purpose of this study is to explore temporal relationships between self-worth and physical activity (PA) participation in middle-aged women (aged 35-64 years).
- Trial name
- NCT02332746
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Arizona State University