Clinical trials: Migraine, completed
Migraine Headache
Intravenous Fluid Therapy for the Treatment of Emergency Department Patients With Migraine Headache
The purpose of this study is to determine whether patients in the emergency department with migraine headache who are administered an intravenous fluid bolus will report greater improvement in pain scores than control patients.
- Trial name
- NCT02933060
- Testing
- Normal saline (1000 mL), Control
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- The Cooper Health System
Migraine
Study to Assess the Safety, Tolerance and Efficacy of Tezampanel in Patients With Acute Migraine
To evaluate the effects of a single sc administration of TEZAMPANEL at one of three different dosage levels compared to placebo, employing traditional measures of efficacy and safety in the treatment of a single episode of acute…
- Trial name
- NCT00567086
- Testing
- TEZAMPANEL
- Where
- United States
- Volunteers
- 306 people
- Sponsor
- TorreyPines Therapeutics
Migraine, Headache
Bioequivalence Study to Compare Ibuprofen/ Paracetamol Tablets (200mg Ibuprofen/ 500mg Paracetamol) Versus Nuromol® Tablets (200mg Ibuprofen/ 500mg Paracetamol)
Randomized, two-way, two-period, single oral dose, open-label, crossover, bioequivalence study to compare Ibuprofen/ Paracetamol tablets (200mg Ibuprofen/ 500mg Paracetamol) versus Nuromol® tablets (200mg Ibuprofen/ 500mg…
- Conditions
- Migraine, Headache, Backache
- Trial name
- NCT06180070
- Testing
- Ibuprofen/ Paracetamol tablets, Nuromol® tablets
- Where
- Jordan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Humanis Saglık Anonim Sirketi
Chronic Migraine, Medication Overuse Headache
Anodal tDCS in Chronic Migraine With Medication Overuse
Non-invasive neuromodulation has been applied in several forms of primary headaches, and its usefulness has been suggested for both episodic and chronic migraine (CM).
- Trial name
- NCT04336267
- Testing
- Transcranial direct current stimulation (tDCS) group
- Volunteers
- 20 people
- Sponsor
- IRCCS National Neurological Institute "C. Mondino" Foundation
Migraine Headache
Effectiveness and Acceptability of MINDFULNESS by Smartphone, for Patients with Chronic Migraine and Medication Overuse
Chronic Migraine is a disabling condition that affects the 2% of migraine population. It is often associated with medication overuse that makes this condition very difficult to treat.
- Trial name
- ChroMig-Smart (NCT04389372)
- Testing
- Mindfulness
- Where
- Italy
- Volunteers
- 38 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Migraine
A Study to Evaluate the Efficacy and Safety of Eptinezumab for the Prevention of Migraine in Participants That Are Not Helped by Previous Preventive Treatments
Evaluation of eptinezumab in the prevention of migraine in participants with unsuccessful prior preventive treatments.
- Trial name
- DELIVER (NCT04418765)
- Testing
- Eptinezumab
- Where
- 138 sites in United States, Belgium and 15 more
- Volunteers
- 892 people
- Sponsor
- H. Lundbeck A/S
Migraine
Efficacy of Zolmitriptan (Zomig) in the Treatment of Migraines in Adolescents
The purpose of this study is to evaluate the effectiveness and safety of Zolmitriptan (Zomig) nasal spray, 5.0 mg, compared with placebo (inactive drug) for 2 migraine headaches over a 3-month period in adolescent patients (aged…
- Trial name
- NCT00617695
- Testing
- Zolmitriptan
- Volunteers
- 247 people
- Sponsor
- Impax Laboratories, LLC
Migraine, Medication Adherence
Identifying Factors Underlying the Discontinuation of Triptans
The objective of this study is to identify reasons migraine patients stop using triptan medications for abortive headache treatment.
- Trial name
- NCT00890357
- Where
- 3 sites in United States
- Volunteers
- 292 people
- Sponsor
- Mayo Clinic
Migraine Headache
Efficacy, Tolerability, and Safety of DFN-15
Efficacy, Tolerability, and Safety of DFN-15 in episodic migraine with or without aura, being conducted at multiple centers in the United States
- Trial name
- NCT03009019
- Testing
- DFN-15 Active
- Where
- 43 sites in United States
- Volunteers
- 631 people
- Sponsor
- BioDelivery Sciences International
Migraine Disorders
A Multicenter Assessment of ALD403 in Frequent Episodic Migraine
The purpose of this study is to assess ALD403 in the prevention of migraine headache in frequent episodic migraineurs.
- Trial name
- PROMISE 1 (NCT02559895)
- Testing
- ALD403
- Where
- 87 sites in United States, Georgia
- Volunteers
- 898 people
- Sponsor
- Alder Biopharmaceuticals, Inc.
Headache, Migraine, Hemorrhage
Using the S100B Protein for Emergency Headache Management Care (S100)
The purpose of this study is to determine the negative predictive value of protein S100B that could exclude subarachnoid and intracranial haemorrhage for patient that present severe headache within the last 3 hours.
- Trial name
- S100 (NCT03490500)
- Where
- 3 sites in France
- Volunteers
- 63 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Migraine
Efficacy and Safety Study of Dysport® Used for Migraine Prophylaxis
The purpose of this study is to evaluate the efficacy of botulinum toxin type A (Dysport®) injections into pericranial muscles compared to placebo to prevent migraine attacks.
- Trial name
- NCT00301665
- Testing
- Botulinum toxin type A
- Where
- 9 sites in Czechia, Poland and 1 more
- Volunteers
- 138 people
- Sponsor
- Ipsen
Migraine
Non-Invasive Neurostimulation For the Relief of Symptoms Associated With Migraine
The purpose of this pilot study is to assess feasibility and clarify the design of future study(ies) to support marketing approval of the GammaCore™ device for the treatment and/or prevention of migraine symptoms.
- Trial name
- NCT01532830
- Testing
- n-VNS
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- ElectroCore INC
Migraine Without Aura
Effect of Riocigaut on Migraine Attack Induction in People With Migraine
This double-blind, randomized, placebo-controlled cross-over clinical trial aims to investigate the effects of riocigaut on migraine inducing properties in people with migraine.
- Trial name
- NCT05750446
- Testing
- Riociguat (BAY 63-2521)
- Where
- Denmark
- Volunteers
- 22 people
- Sponsor
- Danish Headache Center
Migraine Without Aura, Acupuncture
Acupuncture In Migraine Without Aura Patients
The investigators aimed to investigate the effect of acupuncture treatment on attack frequency, pain intensity, and disability in migraine without aura patients who receive prophylaxis treatment.
- Trial name
- NCT04542811
- Testing
- Acupuncture
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Ataturk University
Episodic Migraine
Extension Study to Evaluate the Long-Term Safety and Tolerability of Oral Atogepant for the Prevention of Migraine in Participants With Episodic Migraine
The purpose of this study is to evaluate the safety and tolerability of atogepant 60 mg once a day for the prevention of migraine in participants with episodic migraine.
- Trial name
- NCT03939312
- Testing
- Atogepant
- Where
- 113 sites in United States
- Volunteers
- 685 people
- Sponsor
- Allergan
Migraine, Episodic Migraine
Safety and Tolerability Study of Daily Dosing Rimegepant in Episodic Migraine Prevention
The purpose of this study is to further evaluate the long-term safety and tolerability of daily dosing of rimegepant for the prevention of episodic migraine.
- Conditions
- Migraine, Episodic Migraine, Phonophobia, Photophobia
- Trial name
- NCT05207865
- Testing
- Rimegepant
- Where
- 19 sites in United States
- Volunteers
- 441 people
- Sponsor
- Pfizer
Chronic Migraine, Insomnia
Efficacy of Behavioral Insomnia Treatment for Chronic Migraine
The purpose of this study is to test the efficacy of a brief behavioral insomnia intervention in reducing headache frequency and severity among patients with chronic migraine and insomnia.
- Trial name
- NCT01314651
- Testing
- Stimulus Control and Sleep Restriction, Lifestyle Modification
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Daniel Riche
Migraine, Migraine Disease
Diaphragm Relaxation Techniques, Diaphragmatic Breathing Exercises for Migraine Patients
Migraine is a neurological disease characterized by recurring headaches. It is a significant public health problem of the top reasons for disability throughout the world.
- Conditions
- Migraine, Migraine Disease, Manuel Therapy, Diaphragm Relaxation
- Trial name
- NCT07145372
- Testing
- Manual therapy, Diaphragmatic relaxation technique, Shoulder ROM exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Seda Saka
Migraine Headache
A Double Blind Randomized Controlled of Placebo and Nebulized Lidocaine for Migraine Headache
Migraine headaches have previously been shown to be responsive to intranasal lidocaine in a small study. Using a nebulizer to administer the drug would improve the feasibility of using the treatment.
- Trial name
- NCT00287781
- Testing
- Lidocaine
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Kern Medical Center
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