Clinical trials: Migraine, completed
Chronic Migraine
Physiological Changes With SPG Stimulation in Migraine Patients
Hypothesis: Stimulation of the SPG at low frequencies (20 Hz)is believed to cause a physiological parasympathetic upregulation which increases VMCA, concentration and cephalic vessel diameter.
- Trial name
- NCT02510742
- Testing
- Neurostimulation
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- Danish Headache Center
Migraine
Transcranial Magnetic Stimulation in Episodic Migraine (Magnet-EM)
This study will assess the safety and efficacy of repetitive transcranial magnetic stimulation (rTMS) as new preventive treatment of migraine.
- Trial name
- Magnet-EM (NCT03556722)
- Testing
- Repetitive Transcranial Magnetic Stimulation.
- Where
- Malaysia
- Volunteers
- 76 people
- Sponsor
- Universiti Putra Malaysia
Chronic Migraine
NINDS CRC Chronic Migraine Treatment Trial
The purpose of this study is to compare the reduction in the number of severe headache days at six months in people with chronic migraine treated with topiramate and propranolol versus those treated with topiramate and a placebo.
- Trial name
- CMTT (NCT00772031)
- Testing
- propranolol LA, topiramate
- Where
- 39 sites in United States
- Volunteers
- 191 people, healthy volunteers welcome
- Sponsor
- Anne Lindblad
Migraine
Does a Migraine Medication Decrease Rotational Motion Sickness in People Suffering From Migraines?
The purpose of this study is to determine if Rizatriptan, a migraine medication, lowers motion sickness in migraine sufferers.
- Trial name
- NCT00360282
- Testing
- Rizatriptan
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Pittsburgh
Migraine
Study to Test a Marketed Drug in the Treatment of Menstrual Migraine (0462-072)
The purpose of this study is to test the effectiveness of a marketed drug in the treatment of a menstrual migraine attack.
- Trial name
- NCT00111722
- Testing
- MK0462, rizatriptan benzoate / Duration of Treatment -1day
- Volunteers
- 393 people
- Sponsor
- Organon and Co
Vestibular Migraine, Migraine Associated Vertigo
SENSE-VM: Safety and Effectiveness of a Novel Medical Device for Symptom Ease in Vestibular Migraines
The goal of this virtual clinical trial is to compare the effectiveness of two study devices in providing temporary relief to adults aged 18-75 who suffer from symptoms of chronic Vestibular Migraines (VM), also known as Migraine…
- Trial name
- NCT06267924
- Testing
- Otoband Experimental
- Where
- United States
- Volunteers
- 322 people
- Sponsor
- Otolith Labs
Migraine
A Safety and Efficacy Study to Evaluate AMG 334 in Migraine Prevention
Randomized, double-blind, placebo-controlled, parallel-group, multicenter study followed by an open-label treatment phase (OLTP).
- Trial name
- NCT02630459
- Testing
- Erenumab
- Where
- 44 sites in Japan
- Volunteers
- 475 people
- Sponsor
- Amgen
Migraine
The Safety and Efficacy of Divalproex Sodium Extended-Release Tablets in Migraine Prophylaxis: A Study in Adolescents
The purpose of this study is to determine whether Depakote ER is safe and effective in the reduction of occurrence of migraine headaches in adolescents.
- Trial name
- NCT00195741
- Testing
- divalproex sodium
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Abbott
Migraine, Headaches
Efficacy and Safety of 20 mg Sumatriptan Powder Delivered Intranasally With the Bi-directional Device Compared With 100 mg Sumatriptan Tablets in Adults With Acute Migraine With or Without Aura
This study is being conducted to determine if OPTINOSE SUMATRIPTAN delivered nasally (through the nose) using the OPTINOSE SUMATRIPTAN DEVICE can reduce the pain associated with migraine headaches in 30 minutes after use.
- Trial name
- COMPASS (NCT01667679)
- Where
- 13 sites in United States
- Volunteers
- 275 people
- Sponsor
- Avanir Pharmaceuticals
Migraine
Ictal and Interictal Inflammatory Markers in Migraine
The purpose of this study is to evaluate blood levels of several proteins that may be altered in the inflammation associated with migraine headaches.
- Trial name
- NCT01138150
- Testing
- Treximet
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Johns Hopkins University
Migraine Disorders
BOTOX® Prophylaxis in Patients With Chronic Migraine
This is a post authorization observational study to monitor the utilization practices and describe the safety profile of BOTOX® in clinical practice for the prophylactic treatment of headaches in adult patients with chronic…
- Trial name
- NCT01432379
- Testing
- botulinum toxin Type A
- Where
- 4 sites in Germany, Spain and 2 more
- Volunteers
- 1,168 people
- Sponsor
- Allergan
Migraine
A Study of the Pulmonary Safety and Pharmacokinetics of Zolmitriptan Inhalation Powder
This study is an open-label, parallel group study to evaluate acute pulmonary safety and Pharmacokinetics (PK) of two doses, separated by 2 hours, of CVT-427 zolmitriptan inhalation powder in three groups of adults: those with…
- Trial name
- NCT02905227
- Testing
- CVT-427 (zolmitriptan inhalation powder)
- Where
- 3 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Acorda Therapeutics
Acute Migraine
Transcranial Direct Current Stimulation for Migraine Attack
This study is conducted to investigate the therapeutic efficacy and safety of transcranial direct current stimulation (tDCS) over the primary motor cortex of patients with acute migraine attack.
- Trial name
- NCT01358279
- Testing
- transcranial direct current stimulation
- Where
- South Korea
- Volunteers
- 32 people
- Sponsor
- Seoul National University Hospital
Chronic Migraine
Use of a Treatment Benefit Questionnaire in Patients With Chronic Migraine Treated With OnabotulinumtoxinA (BOTOX®)
This study will evaluate the use of the Assessment of Chronic Migraine Impacts (ACM-I) Questionnaire in assessing the impact and benefit of treatment with onabotulinumtoxinA (BOTOX®) in adults with chronic migraine.
- Trial name
- NCT01833130
- Testing
- OnabotulinumtoxinA
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Allergan
Headache, Migraine, Hemorrhage
Using the S100B Protein for Emergency Headache Management Care (S100)
The purpose of this study is to determine the negative predictive value of protein S100B that could exclude subarachnoid and intracranial haemorrhage for patient that present severe headache within the last 3 hours.
- Trial name
- S100 (NCT03490500)
- Where
- 3 sites in France
- Volunteers
- 63 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Fibromyalgia
Estrogen Receptor 1 Gene Polymorphism Frequency in Fibromyalgia Syndrome
Fibromyalgia Syndrome (FMS) is a chronic musculoskeletal disorder accompanied by diffuse body pain, increased fatigue and tenderness in specific anatomical regions, and sleep disturbance.
- Trial name
- NCT03786393
- Testing
- ACR 1990 fibromyalgia critters
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University
Migraine Disorders, Headache
A Retrospective Chart Review to Evaluate Diagnosis and Treatment of Chronic Migraine and Headache
This study is a retrospective chart review in patients diagnosed with headache or migraine to evaluate treatment patterns and diagnosis.
- Trial name
- NCT01946126
- Testing
- No Intervention
- Where
- United States
- Volunteers
- 459 people
- Sponsor
- Allergan
Migraine
Comparison of Wet Cupping and Acupuncture in Migraine
The aim of this study is to evaluate the effects of wet cupping therapy (WCT) on migraine patients and compare it with acupuncture. The patients will be randomized into three groups.
- Trial name
- NCT05282134
- Testing
- Wet cupping therapy, Acupuncture
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Karabuk University
Migraine, Pain
Nitrous Oxide for Acute Migraine Pain in the Emergency Room (ED)
BACKGROUND Migraine headaches account for 8-18% of all headaches seen in pediatric emergency rooms. Standard treatment includes IV pain medications, anti-emetics, and IV fluids.
- Trial name
- NCT01287052
- Testing
- Nitrous Oxide
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Children's Hospitals and Clinics of Minnesota
Migraine
A Safety Study of Galcanezumab in Participants With Migraine, With or Without Aura
The main purpose of this study is to evaluate the longer term safety of the study drug known as galcanezumab in participants with episodic or chronic migraine.
- Trial name
- NCT02614287
- Testing
- Galcanezumab
- Where
- 27 sites in United States, Belgium and 4 more
- Volunteers
- 270 people
- Sponsor
- Eli Lilly and Company
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