Clinical trials: Mild Cognitive Impairment (MCI)
Alzheimer Disease, Mild Cognitive Impairment
Dementia Signal Development Study of Nautilus NeuroWave TM for the Detection of Dementia
This study is being performed to generate data regarding brain vibration /oscillation differences between individuals with dementia and normal controls.
- Conditions
- Alzheimer Disease, Mild Cognitive Impairment, Frontotemporal Lobar Degeneration, Memory Disorders
- Trial name
- NCT02333942
- Testing
- Nautilus NeuroWaveTM System
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Jan Medical, Inc.
Alzheimer's Disease, Mild Cognitive Impairment
A Clinical Trial of a Vitamin/Nutriceutical Formulation for Alzheimer's Disease
Based on prior published pilot studies, the investigators have initiated a larger, multi-site placebo-controlled clinical trial with Alzheimer's disease (AD) patients and individuals diagnosed with Mild Cognitive Impairment…
- Trial name
- NCT01320527
- Testing
- Nutriceutical formulation
- Where
- 8 sites in United States
- Volunteers
- 135 people
- Sponsor
- University of Massachusetts, Worcester
Alzheimer s Disease, Mild Cognitive Impairment (MCI)
Crownlands Observing Progression With Neurons Study
The CROWN-I Study is an observational study to learn about molecular features of Alzheimer's disease (AD) and mild cognitive impairment (MCI).
- Trial name
- CROWN-I (NCT07611396)
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Crownlands
Frailty, Mild Cognitive Impairment
The Mito-Frail Trial: Effects of MitoQ on Vasodilation, Mobility and Cognitive Performance in Frail Older Adults
The goal of this clinical trial is to test the effects of MitoQ supplementation in older adults and frail older adults with physical dysfunction and/or cognitive dysfunction.
- Conditions
- Frailty, Mild Cognitive Impairment, Aging
- Trial name
- Mito-Frail (NCT06027554)
- Testing
- Mitoquinone Mesylate
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- UConn Health
Frailty, Mild Cognitive Impairment
Influence of Square-stepping Exercise on Brain Activation, Cognitive Function and Physical Performance in Frail Elders With MCI
This study is to elucidate the possible mechanisms of SSE by examining brain activation differences between SSE patterns and usual walking, as well as the relationship between brain activity and SSE performance, between cognitive…
- Trial name
- NCT05173363
- Where
- Taiwan
- Volunteers
- 25 people
- Sponsor
- National Yang Ming Chiao Tung University
Mild Cognitive Impairment
Spanish Translation and Cultural Adaptation of the Memory Support System
This study seeks to translate a proven cognitive treatment for Spanish-speaking Hispanics with subjective memory/cognitive complaints or a diagnosis of mild cognitive impairment (MCI) and their care partners.
- Trial name
- NCT03933085
- Testing
- Memory Support System (MSS)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Mayo Clinic
Alzheimer Disease, Mild Cognitive Impairment
Ultralow Dose PET Imaging of 18F-Florbetapir, 18F-Flutemetamol
The goal of this clinical trial is to evaluate an investigational ultralow dose Positron Emission Tomography (PET) imaging technique for Alzheimer's disease, mild cognitive impairment, other forms of dementia detection and…
- Conditions
- Alzheimer Disease, Mild Cognitive Impairment, Dementia, Healthy Volunteers
- Trial name
- NCT07012993
- Testing
- 18F-Florbetapir or 18F-Flutemetamol
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Akiva Mintz
Alzheimer Disease, Dementia Frontal
Evidence Amyloid Scan EEG Study
The Evidence Amyloid Study EEG (EASE) establishes an open-label, longitudinal cohort study to measure of neurological functioning during the onset and progression of cognitive decline in preclinical Alzheimer's patients using…
- Conditions
- Alzheimer Disease, Dementia Frontal, Mild Cognitive Impairment
- Trial name
- EASES (NCT03644043)
- Testing
- EEG scan
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- Metabolic Therapy Inc.
Mild Cognitive Impairment, Gait
Association of Perceived Occupational Performance and Satisfaction, Balance, Gait, and Fear of Falling in Older Adult With Mild Cognitive Impairment
This study was designed to investigate the occupational performance and balance, gait, and fear of falling in older adults with MCI.
- Conditions
- Mild Cognitive Impairment, Gait, Balance, Occupational Problems
- Trial name
- NCT06513325
- Testing
- Canadian Occupational Performance Measure
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Gulhane School of Medicine
Mild Cognitive Impairment, Prodromal Alzheimer's Disease
Study of AGB101 in Mild Cognitive Impairment Due to Alzheimer's Disease
The primary objective of the study is to evaluate the efficacy of AGB101 on slowing cognitive and functional impairment as measured by changes in the Clinical Dementia Rating-Sum of Boxes (CDR-SB) score as compared with placebo…
- Trial name
- HOPE4MCI (NCT03486938)
- Testing
- AGB101 220 mg tablet
- Where
- 24 sites in United States, Canada
- Volunteers
- 164 people
- Sponsor
- AgeneBio
Obesity, Mild Cognitive Impairment
Improvement of Fish Oil in Obesity With Mild Cognitive Impairment
Eighty-eight patients with obesity with mild cognitive impairment（MCI） from the Multicenter Nutrition and Chronic Disease Cohort, who met the inclusion and exclusion criteria, were selected as study subjects and randomly divided…
- Trial name
- NCT06992726
- Testing
- Fish oil intervention
- Volunteers
- 88 people
- Sponsor
- Weiwei Ma
Mild Cognitive Impairment
Rhythmic Light Therapy for Alzheimer's Disease Patients
The investigator will investigate how light delivering 40 hertz (Hz) affects subjective sleep and cognition in a controlled laboratory study.
- Trial name
- NCT05015478
- Testing
- Tailored Rhythmic Lighting Intervention
- Where
- 2 sites in United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Alzheimer's Disease, Mild Cognitive Impairment
Multiple Dose Trial of MK-4334 in Participants With Alzheimer's Clinical Syndrome (MK-4334-005)
This study will evaluate the safety, tolerability, and pharmacokinetics of MK-4334 administered once daily (QD) in participants with Alzheimer's clinical syndrome receiving a stable, daily dose of donepezil 10 mg, taken orally…
- Trial name
- NCT03740178
- Testing
- MK-4334, Donepepzil
- Sponsor
- Merck Sharp & Dohme LLC
Mild Cognitive Impairment
Effectiveness of an ACT-Based Cognitive Intervention on Quality of Life and Cognitive Function in Elderly Residents With MCI
This study investigates the effects of an Acceptance and Commitment Therapy (ACT)-based cognitive intervention on Quality of Life (QOL) and cognitive function among elderly residents with Mild Cognitive Impairment (MCI) in…
- Trial name
- EACT (NCT06753578)
- Testing
- Acceptance and Commitment Therapy (ACT), standard care
- Where
- Spain
- Volunteers
- 215 people
- Sponsor
- Instituto de Investigación Marqués de Valdecilla
Mild Cognitive Impairment
Efficacy and Safety of Cilostazol in Patients of Vascular Cognitive Impairment-no Dementia (VCIND)
Patients of vascular cognitive impairment-no dementia (VCIND) in one group is prescribed cilostazol,in the other group is prescribed aspirin. Evaluate both of them in cognitive function, MRI and other sides at given time.
- Trial name
- NCT01872858
- Testing
- Aspirin, Cilostazol
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Huashan Hospital
Alzheimer Disease
University of Washington Alzheimer's Disease Research Center (UW ADRC) Imaging & Biomarker Core
This is a cross-sectional, observational study that characterizes research participants with Alzheimer's disease (AD) for their patterns of brain degeneration with the investigational tau positron emission tomography (PET)…
- Trial name
- NCT04437290
- Testing
- investigational radiotracer [18F]MK6240
- Volunteers
- 300 people
- Sponsor
- University of Washington
Mild Cognitive Impairment, Spatial Navigation
Active Navigation Training
Pilot testing and development of an immersive virtual reality system for spatial navigation training in mild cognitive impairment syndrome.
- Trial name
- ANTaging (NCT05768620)
- Testing
- CAVE, TAU
- Where
- Italy
- Volunteers
- 32 people
- Sponsor
- Istituto Auxologico Italiano
Mild Cognitive Impairment (MCI)
Evaluation of the Effect of Healthy Lifestyle Intervention for Patients With Mild Cognitive Impairment
This clinical study aims to evaluate the feasibility and preliminary effectiveness of a comprehensive lifestyle intervention program for patients with mild cognitive impairment.
- Trial name
- NCT06942780
- Testing
- Exercise intervention, Social intervention, Dietary intervention
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Xuanwu Hospital, Beijing
Geriatric Patients in a Pre-rehabilitative Treatment, Mild Cognitive Impairment (MCI)
Monitoring and Cognitive Appraisal: The Etiology of Psychological Disorders and The Divergence Between Behavioural and Self-reported Data
The study investigates the etiology of psychogical disorders from a neuropsychological perspective based on monitoring and cognitive appraisal.
- Trial name
- NCT07137676
- Testing
- AX-CPT, No Interventions
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- St. Franziskus Hospital
Mild Cognitive Impairment
Exploratory Trial in Healthy Adults With Mild Cognitive Impairment,16-week Intervention With Mitocholine™
To evaluate the effect of 16-weeks consumption of Mitocholine on Executive Function and Homocysteine levels in a population experiencing Mild Cognitive Impairment.
- Trial name
- NCT05690724
- Where
- Ireland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mitocholine Ltd
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.