Clinical trials: Military Exposure
Hearing Loss, Noise-Induced
Risk Factors for Hearing Loss as a Result of Exposure to Noise During Military Training in the IDF
As part of the proposed work, the investigators would like to examine whether there is a need to use a training video to train IDF combat soldiers to improve the use of ear plugs and to prevent hearing loss from exposure to…
- Trial name
- NCT03314116
- Testing
- Guidance on auditory protection
- Where
- Israel
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Medical Corps, Israel Defense Force
Burn Pit Exposure, Airborne Hazard Exposure
Project PHOENIX: Molecular Signatures of Burn Pit Exposure
Project PHOENIX is an observational clinical research study designed to characterize molecular, genomic, cellular, and functional features in blood specimens from former U.S.
- Conditions
- Burn Pit Exposure, Airborne Hazard Exposure, Veteran Health, Deployment-Related Toxic Exposure
- Trial name
- PHOENIX (NCT07562243)
- Testing
- Prior Burn Pit Exposure, No Known Burn Pit Exposure
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Creative Medical Technology Holdings Inc
Health Adult Subjects, Exposure Occupational
French Military Firefighters to Assess Relationships Between Exposome and Health.
The aim of the study is to describe professional exposures and health events among French military firefighters (both active-duty personnel and veterans) and identify potential relationships between the exposome (the total…
- Conditions
- Health Adult Subjects, Exposure Occupational, Health Behavior, Risky, Occupational Health
- Trial name
- COMITEX-BSPP (NCT07270627)
- Where
- France
- Volunteers
- 1,811 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Spine Health, Spine Injuries and Disorders
Occupational Exposure to Whole Body Vibration Among U.S. Military Veterans: Acute and Chronic Contributions to Musculoskeletal Disorders and Spine-Area Pain
Significance to VA: There is a lack of prospective longitudinal studies investigating the relationship between risk factors to Veterans and development and progression of musculoskeletal (MSK) spine injury and pain.
- Conditions
- Spine Health, Spine Injuries and Disorders, Spine Degeneration, Whole Body Vibration
- Trial name
- NCT07367139
- Testing
- Water
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Milwaukee VA Medical Center
PFAS, Environmental Exposures
Use of Bile Acid Binding Resins to Decrease PFAS Levels Via Colesevalem in Veterans Study
The goal of this study is to test the efficacy and feasibility of Colesevelam administration (50% of the recommended dose) to reduce serum PFAS concentration in the Veteran population who have serum PFAS levels that exceed the…
- Conditions
- PFAS, Environmental Exposures, Occupational Exposure to Chemicals, Military Exposure
- Trial name
- PAVERS (NCT07592858)
- Testing
- Colesevelam
- Where
- 3 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Rhode Island
Burn Pit Exposure
Tele-Exercise for MERP
During Operations Desert Shield and Desert Storm, Veterans in combat were exposed to a variety of airborne hazards, including oil well fire smoke, emissions from burn pits, and other substances associated with negative health…
- Trial name
- TEMPO (NCT07018466)
- Testing
- Tele-exercise, Standard of Care
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Gastrointestinal Injury, Acute Mountain Sickness
Gut-microbiota Targeted Nutritional Intervention for Gut Barrier Integrity at High Altitude
The aim of this randomized, crossover clinical trial is to determine the efficacy of a gut microbiota-targeted nutritional intervention containing a blend of fermentable fibers and polyphenols (FP) for mitigating increases in GI…
- Trial name
- NCT04111263
- Testing
- FP, High altitude, Sea level
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Cold-water Immersion, High Heat Sauna
Thermodynamic Exposure and Sleep in Military Cadets
This pilot study investigates the effects of cold-water immersion, traditional sauna use, and their combination on sleep architecture and psychological health in military cadets.
- Conditions
- Cold-water Immersion, High Heat Sauna, Combination of Cold-water Immersion and High Heat Sauna
- Trial name
- NCT07201935
- Testing
- Cold Water Immersion, High Heat Sauna
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Stress Disorders, Post-Traumatic
Combining Stellate Ganglion Block With Prolonged Exposure for PTSD
The goal of this clinical trial is to compare the combination of Massed Prolonged Exposure (PE); a behavioral therapy for PTSD) and a stellate ganglion block (SGB; an injection of a local anesthetic into the front of the neck)…
- Trial name
- NCT05889741
- Testing
- Ropivacaine injection, Normal saline
- Where
- 2 sites in United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Post Traumatic Stress Disorder, Written Exposure Therapy
Behavioral Health Technician Delivered Written Exposure Therapy
This study has two main goals. First, it aims to test a treatment called written exposure therapy to see if it can help military service members who have posttraumatic stress disorder (PTSD).
- Trial name
- NCT06789887
- Testing
- Written Exposure Therapy, Treatment as Usual (TAU)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Palo Alto Veterans Institute for Research
Post-traumatic Stress Disorder (PTSD)
Prospective Cohort Study of Accelerated Resolution Therapy (ART) for Treatment of Military Psychological Trauma
This is a prospective cohort treatment intervention study (n=200) whereby U.S. service members and veterans with symptoms of PTSD will undergo 2-5 sessions of ART delivered by Florida licensed mental health professionals trained…
- Trial name
- NCT02030522
- Testing
- Accelerated Resolution Therapy (ART)
- Where
- 8 sites in United States
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Traumatic Brain Injury
Impact of Pre-Military Life Experiences/Exposures on Active-Duty Service Members' Psychological Health
The goal of this observational study is to learn about the impact of historic and current Traumatic Brain Injuries on a Marine Battalion.
- Trial name
- NCT06070025
- Where
- United States
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- University of Southern California
PTSD
Effectiveness of Trauma Management Therapy and Prolonged Exposure Therapy
The purpose of this requirement is to identify an effective exposure psychotherapy paradigm for the treatment of Post-Traumatic Stress Disorder (PTSD) in active duty service members and veterans by comparing different exposure…
- Trial name
- NCT04549493
- Testing
- Exposure Therapy
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Posttraumatic Stress Disorder
Couple HOPES and COVID-19
Posttraumatic Stress Disorder (PTSD) will be a severe problem in Canada in the wake of COVID-19, especially for Military Members, Veterans, First Responders, and Healthcare Workers (MVFH).
- Trial name
- HOPES (NCT04763681)
- Testing
- Couple HOPES Guided, Internet-Delivered, Self-Help Intervention
- Where
- Canada
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- York University
Iraq and Afghanistan Era Veterans
Service and Health During the Iraq and Afghanistan Era
The primary objective of CSP #595, "Service and Health During the Iraq and Afghanistan Era," is to characterize the impact of deployment to Iraq and Afghanistan on the respiratory health of Veterans.
- Trial name
- CSP #595 Pilot (NCT01987401)
- Where
- 2 sites in United States
- Volunteers
- 1,242 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
PTSD
Implementation of Prolonged Exposure in the Military
This randomized study examines how prolonged exposure (PE) therapy, an evidence-based treatment for posttraumatic stress disorder (PTSD), can be successfully disseminated and implemented in the Army.
- Trial name
- NCT02982538
- Testing
- Extended Training in Prolonged Exposure Therapy for PTSD, Standard Training in Prolonged Exposure Therapy for PTSD
- Where
- 3 sites in United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Mental Health, Stress Disorders, Post-Traumatic
Integrating Clinical Practice Guidelines for Smoking Cessation Into Mental Health Care for Veterans With Posttraumatic Stress Disorder
The primary study objective is to conduct a prospective, randomized controlled clinical trial that compares the effectiveness of two approaches for delivering smoking cessation treatment for veterans with posttraumatic stress…
- Conditions
- Mental Health, Stress Disorders, Post-Traumatic, Substance-Related Disorders, Tobacco Use Disorder
- Trial name
- NCT00118534
- Testing
- Integrated Care for Smoking Cessation in PTSD patients, Standard of Care
- Where
- 11 sites in United States
- Volunteers
- 943 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Pulmonary Function
Service and Health Among Deployed Veterans
The purpose of the study is to better understand the health, including lung health, of Veterans who deployed in support of Operation Enduring Freedom (OEF), Operation Iraqi Freedom (OIF), or Operation New Dawn (OND) and other…
- Trial name
- SHADE (NCT02825654)
- Where
- 6 sites in United States
- Volunteers
- 6,200 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development