Clinical trials: Mini-Mental State Examination
Missing Posterior Occlusal Contact
Brain and Cognitive Function of Patients With RPD
To evaluate the influence of restoring lost posterior occlusal contacts with removable partial denture (RPD) on the brain activity and cognitive function in controlled type 2 diabetic patients
- Trial name
- NCT04554199
- Testing
- Flexible partial denture
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- National Research Centre, Egypt
Dementia With Lewy Bodies
Study To Evaluate the Efficacy, Safety and Tolerability of E2027 (Hereinafter Referred to as Irsenontrine) in Participants With Dementia With Lewy Bodies
This study will be conducted to compare Irsenontrine to placebo on the cognitive endpoint of Montreal Cognitive Assessment (MoCA) and the global clinical endpoint of Clinician's Interview Based Impression of Change Plus…
- Trial name
- NCT03467152
- Testing
- Irsenontrine
- Where
- 74 sites in United States, France and 5 more
- Volunteers
- 326 people
- Sponsor
- Eisai Inc.
Postoperative Cognitive Dysfunction
Minimal-flow Anesthesia and Cognitive Outcomes in Elderly Surgical Patients
Purpose: Postoperative cognitive dysfunction (POCD) is a common complication in elderly patients following major surgery and is associated with impaired attention, memory, and executive functions.
- Trial name
- NCT07424729
- Testing
- Mini-Mental State Examination
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Ankara Etlik City Hospital
Menstrual Cycle, Optic Nerve Sheath Diameter
Effects of Menstrual Cycle on Optic Nerve Sheath Diameter in Patients Undergoing Laparoscopic Gynecologic Surgery
This observational study aims to evaluate the effect of menstrual cycle phase on optic nerve sheath diameter (ONSD) in women undergoing elective laparoscopic gynecologic surgery.
- Conditions
- Menstrual Cycle, Optic Nerve Sheath Diameter, Postoperative Nausea and Vomiting
- Trial name
- NCT07539831
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Konya City Hospital
Quality Of Recovery
Effect of Preoperative Oral Carbohydrate Loading on Elderly Patient Quality of Recovery in Total Knee Arthroplasty
This prospective randomized controlled study will be aimed to evaluate the effect of preoperative oral carbohydrate loading on the elderly patient's quality of recovery and satisfaction in undergoing knee arthroplasty (TKA)…
- Trial name
- NCT05582356
- Testing
- Carbohydrate group (Group OC)
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Karaman Training and Research Hospital
Alzheimer's Disease, Dementia
Safety and Efficacy of High Dose, Rapid Titration Galantamine in Patients With Alzheimer's Disease
The purpose of this study was to determine the safety and effectiveness of a relatively high dose of galantamine, 32 mg /day in a three-times daily dosage, compared with placebo in treating patients with Alzheimer's disease.
- Trial name
- NCT00338117
- Testing
- Galantamine hydrobromide
- Volunteers
- 554 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Fibromyalgia Syndrome, Fibromyalgia
Can a Relaxometer Improve Cognitive Impairment of Fibromyalgia Patients
The aim of the study is to evaluate the differences in cognitive performance and quality of life, after a cycle of treatment with the relaxometer, between a group of patients affected by fibromyalgia and a control group.
- Conditions
- Fibromyalgia Syndrome, Fibromyalgia, Pain, Chronic, Impairment
- Trial name
- Fibrorilax (NCT04170387)
- Testing
- Relaxometer
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Alzheimer Disease, Mini-Mental State Examination
Predictive Factors for Initial MMSE Score and Rapid Decline in Alzheimer's Disease Patients
This study looks at people with Alzheimer's disease to find out which factors are linked to their initial score on the Mini-Mental State Examination (MMSE) and which factors may predict a fast decline in their score over 12…
- Conditions
- Alzheimer Disease, Mini-Mental State Examination, Cognitive Dysfunction, Neuropsychological Tests
- Trial name
- NCT07122856
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier de Gonesse
ATRIAL FIBRILLATION
Blinded Randomized Trial of Anticoagulation to Prevent Ischemic Stroke and Neurocognitive Impairment in AF
This is a prospective, multicenter, randomized, double-blinded clinical trial exploring the efficacy and safety of rivaroxaban as compared to standard of care in reducing stroke, transient ischemic attack (TIA) and neurocognitive…
- Trial name
- BRAIN-AF (NCT02387229)
- Testing
- Rivaroxaban, standard of care
- Where
- 41 sites in Canada
- Volunteers
- 1,238 people
- Sponsor
- Montreal Heart Institute
Stroke, Cerebrovascular Disease
Functional Changes and Home Discharge After Inpatient Stroke Rehabilitation
This retrospective observational study will evaluate whether changes in functional status during inpatient rehabilitation are associated with discharge destination in patients with stroke treated at a post-acute rehabilitation…
- Trial name
- NCT07502326
- Testing
- Inpatient Rehabilitation
- Where
- South Korea
- Volunteers
- 119 people
- Sponsor
- SeongKi Min
Alzheimer s Disease, Vascular Cognitive Impairment
Adaptation of the Mini-Mental State Examination (MMSE) for the Reunion Island Population
The Mini-Mental State Examination (MMSE) is the most widely used cognitive screening and monitoring test for neurocognitive disorders in current clinical practice.
- Trial name
- MMSE-RUN (NCT07251647)
- Testing
- MMSE-RUN and MMSE GRECO
- Where
- 7 sites in Reunion
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Alzheimer Dementia, Dementia Disorders
Medication Repurposing to Stop Cognitive Decline in Dementia
Dementia creates a great personal and societal burden and there are currently no treatments to stop memory loss. Many patients with dementia take medications to treat other conditions, e.g. high blood pressure and cholesterol.
- Trial name
- NCT05817188
- Testing
- No intervention
- Where
- Sweden
- Volunteers
- 100,000 people
- Sponsor
- Karolinska Institutet
Postoperative Cognitive Dysfunction
Postoperative Cognitive Dysfunction in Elderly
Interventional Study of Early Postoperative Cognitive Dysfunction in Elderly Patients Undergoing General Anesthesia The main purpose of this study is to determine the incidence of early postoperative cognitive dysfunction in…
- Trial name
- ElderlyPOCD (NCT02068742)
- Testing
- battery neuropsychological tests
- Where
- Italy
- Volunteers
- 160 people
- Sponsor
- Università degli Studi dell'Insubria
Gait Disorder, Sensorimotor, Diabetes Mellitus, Type 2
Factors That Effect the Gait Speed in Diabetic Individuals Without Neuropathy
This study planned to investigate the role of potential explanatory factors effecting the speed of gait such as muscle mass, aerobic capacity, physical activity status, cognitive function, blood pressure, and metabolic measures…
- Trial name
- NCT04758364
- Testing
- measurement of gait speed
- Where
- Turkey (Türkiye)
- Volunteers
- 71 people
- Sponsor
- GULIN FINDIKOGLU
Neurocognitive Disorder, General Anesthesia
EVALUATION OF POSTOPERATIVE NEUROCOGNITIVE IMPAIRMENT
In this prospective study, the effects of different anesthesia methods (total intravenous anesthesia and inhaled anesthesia) on neurocognitive function will be examined in patients undergoing breast-conserving surgery without…
- Conditions
- Neurocognitive Disorder, General Anesthesia, Total Intravenous Anesthesia, Sevoflurane Anaesthesia
- Trial name
- NCT06685770
- Testing
- Mini mental state assessment test, Mini-cog test
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Haseki Training and Research Hospital
Cognitive Recovery, Sedation
Effects of Different Sedation Techniques on Early Cognitive Recovery After Ambulatory Gynecologic Surgery
This prospective, randomized, double-blind clinical trial aims to compare the effects of three commonly used sedoanalgesia regimens on early cognitive recovery in patients undergoing ambulatory gynecologic surgery (dilatation and…
- Conditions
- Cognitive Recovery, Sedation, Ambulatory Gynecologic Surgery, Postoperative Recovery
- Trial name
- SEDCOG (NCT07267377)
- Testing
- Propofol-Fentanyl, Ketamine-Fentanyl, Propofol + Ketamine + Fentanyl (Ketofol)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Sait Fatih Öner
Deep Hypnotic Time, Emergence Time
Comparison of DHT Duration in Geriatric Patients Using BIS Monitoring
Without adequate monitoring, administration of anesthetic agents can create unnecessary deeper anesthetic plane in geriatric population.
- Conditions
- Deep Hypnotic Time, Emergence Time, Geriatric Population, General Anesthesia
- Trial name
- NCT06394362
- Testing
- Bispectral index monitor
- Where
- Indonesia
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Cognitive Decline, Cognitive Dysfunction
Open-label, Post-marketing, Prospective Study to Assess Impact of COVID-19 on Cognitive Function in Patients
The objective of this study is to compare the impact of the coronavirus disease (SARS-CoV-2, or COVID-19) on cognitive function in the population of patients who have been diagnosed, treated and recovered from the COVID-19…
- Conditions
- Cognitive Decline, Cognitive Dysfunction, Brain Health, Post CoV-2 Syndrome
- Trial name
- COVID19 (NCT04950673)
- Testing
- Cognivue
- Where
- 4 sites in United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Cognivue, Inc.