Clinical trials: Minimally Invasive Surgery
Surgery Complications, Surgery
SurgWeek-2: Identifying the Global Burden of Post Operative Complications: an International Prospective Cohort Study Protocol
This study aims to assess and improve the global outcomes following surgery. Every year approximately 313 million operations are performed, with 50 million people experiencing a complication and unfortunately 3.5 million people…
- Conditions
- Surgery Complications, Surgery, Global Surgery, Robotic
- Trial name
- SurgWeek-2 (NCT07785076)
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Coronary Artery Disease (CAD), Bypass, Cardiopulmonary
Multivessel Minimally Invasive Coronary Bypass Grafting as HYBRID Revascularization Versus Conventional Off-pump Coronary Artery Bypass Grafting
The MICRA-HYBRID trial is a prospective, multicenter, randomized controlled study comparing multivessel hybrid coronary revascularization (HCR) as minimally invasive arterial bypass grafting to left-sided coronary targets (LAD…
- Conditions
- Coronary Artery Disease (CAD), Bypass, Cardiopulmonary, Minimally Invasive Coronary Revascularization Surgery, Off-pump Coronary Artery Bypass
- Trial name
- MICRA-HYBRID (NCT07314138)
- Testing
- Multivessel Hybrid Coronary Revascularization, Off-pump coronary arterial bypass grafting (OPCAB)
- Where
- 2 sites in Belgium, Netherlands
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Catharina Ziekenhuis Eindhoven
Surgical Simulation Education
Assessment of the Transferability of Skills From Robotic to Laparoscopic Simulation Platforms
This is a randomized controlled trial that will randomize 40 surgical skill naive medical students to practice on a robotic simulator or laparoscopic simulator after first completing a baseline evaluation on both surgical…
- Trial name
- NCT02370407
- Testing
- a laparoscopic simulator (Fundamentals of Laparoscopic Surgery (FLS), VT Medical Inc, Waltham, MA), Mimic da Vinci robotic simulator
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Periodontal Diseases
Effect of Internal and External Micro-needling in Treatment of Stage III Periodontitis
Periodontitis is a dysbiotic disease characterized by the destruction of the periodontium (alveolar bone, cementum, periodontal ligament, gingiva) and considered the main cause of tooth loss which is linked to a change in the…
- Trial name
- NCT06578403
- Testing
- external microneedling, minimally invasive non- surgical periodontal therapy, internal micro_needling
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Misr University for Science and Technology
Periareolar Minimally Invasive Cardiac Surgery
Periareolar Approach in Minimally Invasive Cardiac Surgery
Overall Goal: To study the feasibility and safety of "periareolar minimally invasive surgery" protocol in patients undergoing periareolar minimally invasive surgery vs. Control group (inframammary approach).
- Trial name
- PAMI (NCT04726488)
- Testing
- Periareolar Approach in Minimally Invasive Cardiac Surgery (PAMI Technique), inframammary approach
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Assiut University
Intrabony Periodontal Defect
Clinical and Radiographic Evaluation of the Entire Papilla Preservation (EPP) Technique Versus Modified Minimally Invasive Surgical Technique (M-MIST) in Treatment of Intraosseous Defects in Patients With Stage III Periodontitis: A Randomized Clinical Trial
Periodontitis is defined as loss of periodontal attachment due to microbial associated host mediated inflammation. This would lead to the apical migration of the junctional epithelium allowing the bacterial biofilm to undergo…
- Trial name
- NCT04100798
- Testing
- Entire Papilla Preservation technique, Modified Minimally invasive Surgical Technique
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Cairo University
Trigger Thumb
Study of Open and Percutaneous Release of Acquired Trigger Thumb
Trigger finger, also known as trigger digit or stenosing tenovaginitis, is caused by a size mismatch between the flexor tendon and the A1 pulley, which is generally characterized by pain, swelling, the limitation of finger range…
- Trial name
- NCT03679793
- Testing
- Open Release Group, Percutaneous Release Group
- Where
- Hong Kong
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Surgical Technique
A Randomized Controlled Trial of Open Surgical vs. Minimally-invasive Voluntary Adult Male Circumcision
This proposed randomized controlled trial will provide important data which will inform and enable the Mozambican government and global health programs to more effectively scale-up circumcision services.
- Trial name
- NCT01688310
- Testing
- Gomco Clamp with Tissue Adhesive, Open surgical circumcision
- Where
- Mozambique
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Universidade Católica de Moçambique
Distal Cholangiocarcinoma
Minimally Invasive Pancreatoduodenectomy for Distal Cholangiocarcinoma
Outcomes for minimally invasive and open pancreatoduodenectomy for distal cholangiocarcinoma have not been compared. This is an international multicenter propensity score matched cohort study including patients after MIPD or OPD…
- Trial name
- NCT05478889
- Testing
- Minimally invasive pancreatoduodenectomy
- Where
- Italy
- Volunteers
- 478 people, healthy volunteers welcome
- Sponsor
- Fondazione Poliambulanza Istituto Ospedaliero
Degenerative Spine Diseases, Surgical Wound
Effect of Topical Tranexamic Acid on Postoperative Drainage in Minimally Invasive Transforaminal Lumbar Interbody Fusion (MI-TLIF)
The randomized controlled study which compare the efficacy outcomes (reducing blood loss and drainage output in patients) in patients undergoing single-level minimally invasive transforaminal lumbar interbody fusion (MI-TLIF) and…
- Trial name
- NCT06427850
- Testing
- Tranexamic acid, Normal saline
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Thanawan Longsuwan
Intrabony Periodontal Defects
Minimally Invasive Non Surgical Treatment Using Injectable Platelet Concentrate in Treatment of Deep Pockets.
The purpose of this study is to evaluate change in pocket depth following using minimally invasive non surgical combined with injectable platelet concentrate .
- Trial name
- NCT07722390
- Testing
- Injectable PRF, MINST
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Cairo University
Colorectal Disorders, Regional Anesthesia Morbidity
Transversus Abdominis Plane Blocks With and Without Dexamethasone
Dexamethasone will be used as an adjunct to local anesthetics (bupivacaine) to prolong the duration of laparoscopically-placed transversus-abdominis plane blocks in elective colorectal resection.
- Conditions
- Colorectal Disorders, Regional Anesthesia Morbidity, Analgesia, Local Anesthetic Complication
- Trial name
- TAP-DEX (NCT05432934)
- Testing
- Dexamethasone
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Post-operative Pain, Gynecologic Surgery
Ultrasound Guided Posterior Quadratus Lumborum Block for Postoperative Analgesia in Gynecologic Surgery
The challenge to achieve adequate analgesia has led to the development of directed, multi-modal protocols specific to management of post-laparoscopy pain in effort to decrease the amount of additional administration of narcotic…
- Conditions
- Post-operative Pain, Gynecologic Surgery, Regional Anesthesia
- Trial name
- NCT04549090
- Testing
- QL (quadratus lumborum) block administration
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Pedram Bral
Osteoarthritis, Knee
Technology and System for Minimally Invasive TKA Surgery Robot
Developed a robot for minimally invasive TKA surgery and prepare for the subsequent CFDA application of the minimally invasive total knee replacement robot system.
- Trial name
- NCT04953988
- Testing
- Robotic TKA, Manual operation
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Postoperative Pain, Narcotic Use
Novel Multimodal Pain Control Protocol for Minimally Invasive Gynecologic Surgery
The study is a randomized controlled trial investigating a multimodal postoperative pain management protocol which will include use of ice therapy and scheduled opioid-sparing medications for pain control after minimally invasive…
- Conditions
- Postoperative Pain, Narcotic Use, Cryotherapy Effect
- Trial name
- NCT04710277
- Testing
- Opioid-sparing multimodal pain management, Usual care
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Periodontal Regeneration, Clinical and Radiographic Results, Modified Minimal Invasive Surgery
Evaluation of Healing of Intra-bony Defects in Modified Minimal Invasive Surgical Technique
This study is aiming to compare the clinical and radiographic outcomes after complete versus incomplete removal of granulation tissue during modified minimally invasive surgical technique for management of periodontal intrabony…
- Trial name
- NCT03562039
- Testing
- M-MIST
- Where
- 2 sites in Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Cairo University
Minimally Invasive Surgical Technique, Open Flap Debridement
Evaluation of Gain In Clinical Attachment And Bone Levels After Treatment of Patients With Intra-bony Defects By Minimally Invasive Surgical Technique Versus Open Flap Debridement.
Hypothesis:The conventional surgical approach is to raise large flaps to completely and exceedingly expose the area of interest.
- Conditions
- Minimally Invasive Surgical Technique, Open Flap Debridement, Microsurgery
- Trial name
- NCT03570736
- Testing
- Minimal invasive surgical technique, Open Flap Debridement
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
Periodontitis
The Use of Adhesion Molecule Loaded Hydrogel With Minimally Invasive Surgical Technique in Treatment of Periodontal Intrabony Defect
Primary aim of the study is to evaluate efficacy of RGD adhesion molecule loaded hydrogel with minimally invasive surgical technique in treatment of periodontal intrabony defect at baseline and 6months.
- Trial name
- NCT05653245
- Testing
- RGD Peptide
- Where
- 2 sites in Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Minia University
Surgery
Development and Validation of a Virtual Teaching Method for Minimally Invasive Surgery Skills
The goal of this observational study is to develop and evaluate a virtual teaching method for minimally invasive surgery (MIS) skills among novice learners, using widely available technology and incorporating objective…
- Trial name
- NCT06355596
- Testing
- Virtual teaching
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Imperial College London
No Disease or Condition is Being Studied, Surgical Procedures, Minimally Invasive
Hand Versus Foot Controls for Robotic Surgery Simulation
Why is the study being done? Robotic-assisted surgery offers high precision and ergonomic benefits, but it requires specialized console skills that differ significantly from traditional open or laparoscopic surgery.
- Trial name
- CLUTCH WAR (NCT07618429)
- Testing
- Hand Clutch, Foot Clutch
- Where
- Thailand
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Prince of Songkla University