Clinical trials: Minor Depression
Depression Minor
Probing Homeostatic Plasticity With Priming Theta-burst Stimulation of the Dorsolateral Prefrontal Cortex
Priming stimulation is a highly promising tool to boost the beneficial effects of therapeutic repetitive transcranial magnetic stimulation (rTMS) in psychiatry.
- Trial name
- NCT04031105
- Testing
- Theta-burst stimulation (TBS)
- Where
- Hong Kong
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Dr Georg Kranz
Depressive Symptoms, Aging
ABSORB (Amount of Blueberries So Older Adults Reap Benefits)
This randomized, cross-over, pilot study aims to compare preliminary impact of a standard dose of blueberry powder (24 g) vs a higher dose (48 g) on the bioavailability of flavonoids and inflammatory biomarkers in older adults…
- Trial name
- NCT05937165
- Testing
- Freeze-dried Blueberry Powder
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Hebrew SeniorLife
Depressive Disorder, Major, Depressive Disorder, Minor
Enhanced Collaborative Depression Treatment in Primary Care: The RESPECT-D-E Trial
Primary care physicians have emerged as the predominant mental health care providers for diagnosing and treating depression. The majority of patients with mood disorders receive treatment in the primary care setting, within which…
- Conditions
- Depressive Disorder, Major, Depressive Disorder, Minor, Dysthymic Disorder
- Trial name
- NCT01583400
- Testing
- RESPECT-D, RESPECT-D-E (Enhanced)
- Where
- United States
- Volunteers
- 131 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Mental Disorders
Study of Mindfulness-based Group Treatment in Patients With Depression and Anxiety
The purpose of this study is to determine the effectiveness, with respect to symptoms and systemic inflammatory level, of mindfulness-based group treatment compared with normal treatment in patients diagnosed with minor to…
- Trial name
- NCT01476371
- Testing
- Mindfulness-based group treatment
- Volunteers
- 215 people
- Sponsor
- Lund University
Depression
Reducing the Risk of Developing Major Depression in Adolescents/Young Adults With Minor Depression/Depression Symptoms
The purpose of this research study is to assess the feasibility of a combined primary care/web-based depression prevention intervention.
- Trial name
- NCT00145951
- Testing
- motivational interviewing, brief advice in primary care
- Where
- United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Depression
Primary Prevention of Major Depression in Later Life
The Institute of Medicine has called for studies of "indicated" preventive interventions to reduce the incidence of mental illness in persons already symptomatic but not yet presenting with fully developed clinical syndromes.
- Trial name
- NCT00326677
- Testing
- Problem Solving Therapy, Dietary Education
- Where
- 2 sites in United States
- Volunteers
- 306 people
- Sponsor
- University of Maryland, College Park
Perimenopausal Depression, Post Menopausal
The Effects of Estrogen Withdrawal on Mood Symptoms in Women
This study evaluates the effects on mood when stopping estrogen replacement therapy. The purpose of this study is to investigate the effects of estrogen levels on perimenopausal depression.
- Conditions
- Perimenopausal Depression, Post Menopausal, Healthy, Depression
- Trial name
- NCT00060736
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- National Institute of Mental Health (NIMH)
Major Depressive Disorder, Minor Depressive Disorder
Evaluation of a Stepped Care Approach to Manage Depression in Diabetes
The study examines the efficacy of a stepped care approach for depressed diabetes patients (first study objective). 256 patients with diabetes and comorbid subthreshold or clinical depression will be randomly assigned to either a…
- Conditions
- Major Depressive Disorder, Minor Depressive Disorder, Sub-Threshold Depression, Diabetes Mellitus
- Trial name
- Ecce_homo (NCT01812291)
- Testing
- Step 1: Diabetes-Specific CBT (5 group sessions), Step 2: Depression-Specific CBT (6 single sessions), Step 3: Referral to Psychotherapist and/or Psychiatrist
- Where
- Germany
- Volunteers
- 260 people
- Sponsor
- Forschungsinstitut der Diabetes Akademie Mergentheim
Minor Depressive Disorder, Major Depressive Disorder
"Mamá, te Entiendo" App-based Intervention for Reducing Depressive Symptoms in Postpartum Women
Title: "Feasibility and acceptability study of "Mamá, te entiendo": an app-based intervention for reducing depressive symptoms in postpartum women" Funding: This work was funded by the Chilean National Agency of Research and…
- Conditions
- Minor Depressive Disorder, Major Depressive Disorder, Post Partum Depression
- Trial name
- NCT05643898
- Testing
- Mamá, te entiendo (Mom, I get you)
- Volunteers
- 66 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Depressive Symptoms, Diabetes Mellitus
Evaluation of a Diabetes-specific Cognitive Behavioural Treatment for Subthreshold Depression
This work is supported by the "Kompetenznetz Diabetes mellitus (Competence Network for Diabetes mellitus)" funded by the Federal Ministry of Education and Research (FKZ 01GI0809).
- Trial name
- NCT01009138
- Testing
- Diabetes-Specific CBT (DS-CBT), Standard Diabetes Education
- Where
- Germany
- Volunteers
- 214 people
- Sponsor
- Forschungsinstitut der Diabetes Akademie Mergentheim
Insomnia, Major Depression
New Clinical Applications for Internet-based Cognitive Behavior Therapy for Insomnia and Depression
This study includes two sub-trials. Both are included in this singe registration since they have parallel inclusion of participants and have been approved by the Swedish ethics board together in one application.
- Conditions
- Insomnia, Major Depression, Minor Depression
- Trial name
- NCT01663844
- Testing
- Therapist guided Internet-CBT for insomnia w. extra support, Therapist guided Internet-CBT for insomnia, Therapist guided Internet-CBT for insomnia and depression
- Where
- Sweden
- Volunteers
- 440 people
- Sponsor
- Karolinska Institutet
Depression
Drug Therapy to Treat Minor Depression
This 6-month study will compare the effectiveness of citalopram (Celexa®), hypericum (St. John's Wort), and placebo for the treatment of minor depression.
- Trial name
- NCT00048815
- Testing
- Citalopram, St. John's Wort
- Where
- 3 sites in United States
- Volunteers
- 73 people
- Sponsor
- Massachusetts General Hospital
Depression, Anxiety
Effects of an Integrative Treatment Model to Reduce Anxiety and Depression in Minor Mental Health Problems and Medically Unexplained Symptoms
Minor mental health problems, MMHP, like mild depression and anxiety, and medically unexplained symptoms, MUS, symptoms with no known underlying organic disease, are strongly associated to each other.
- Conditions
- Depression, Anxiety, Irritable Bowel Syndrome, Fibromyalgia
- Trial name
- NCT01631500
- Testing
- Conventional treatment, Integrative treatment, Therapeutic acupuncture
- Where
- Sweden
- Volunteers
- 120 people
- Sponsor
- Göteborg University
Post Traumatic Stress Disorder, Depression
Acceptance and Commitment Group Therapy for Unaccompanied Minors
Unaccompanied minors (UM) are considered to be a highly vulnerable refugee subgroup. Research has indicated that UM experience traumatic events and consequently develop high levels of psychopathology.
- Conditions
- Post Traumatic Stress Disorder, Depression, Anxiety Disorders
- Trial name
- NCT05218031
- Testing
- Acceptance and Commitment Therapy
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Cyprus
Repetitive Negative Thinking, General Anxiety Disorder
Training Protocol 'Drop it'. The Impact of a Training Protocol Focused on Coping With Negative Repetitive Thinking on Cognitive and Behavioural Functioning of People Suffering From GAD or Minor or Moderate Depressive Disorder or Depressive Disorder in Remission
Repetitive negative thinking (RNT) plays an important role in different psychiatric disorders, such as depressive and anxiety disorders, complicated grief, posttraumatic stress disorders, anorexia nervosa.
- Conditions
- Repetitive Negative Thinking, General Anxiety Disorder, Depressive Disorder, Depression
- Trial name
- Drop It (NCT01983033)
- Testing
- Drop It training session, treatment as usual
- Where
- Belgium
- Volunteers
- 80 people
- Sponsor
- University Hospital, Ghent
Post-Traumatic Stress Disorder (PTSD), Depressive Symptoms
Trauma-Focused Cognitive Behavioral Therapy in Unaccompanied Refugee Minors With PTSD in Greece: An RCT
This single-blinded, multicentered, randomized controlled trial aims to evaluate the effectiveness of Trauma-Focused Cognitive Behavioral Therapy (TF-CBT) compared to Treatment-as-Usual (TAU) in reducing post-traumatic stress…
- Conditions
- Post-Traumatic Stress Disorder (PTSD), Depressive Symptoms, Anxiety Symptoms, Somatic Symptoms
- Trial name
- TF-CBT (NCT06975280)
- Testing
- Trauma - Focused Cognitive Behavioral Therapy, Treatment as Usual (TAU)
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- Theodora Anastasiou
Major Depression, Minor Depression
Neuropattern - Assessment of a Translational Diagnostic Tool for Depression, Adjustment- and Somatoform-disorders
Neuropattern is a first translational tool in stress medicine. Neuropattern is a diagnostic tool, which can be applied by in- and outpatients and physicians to detect dysregulation in the stress response network.
- Conditions
- Major Depression, Minor Depression, Somatoform Disorders, Adjustment Disorders
- Trial name
- Neuropattern (NCT01062880)
- Testing
- self-guided internet modules
- Where
- Germany
- Volunteers
- 2,000 people
- Sponsor
- University of Trier
Dysthymic Disorder, Depressive Disorder NOS
Duloxetine for Chronic Depression: a Double-blind Study
The investigators are studying a new antidepressant medicine, duloxetine, for the treatment of people with chronic depression. Duloxetine (trade name Cymbalta) was recently approved by the FDA for the treatment of major…
- Trial name
- NCT00360724
- Testing
- Duloxetine (Cymbalta)
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- New York State Psychiatric Institute