Clinical trials: Minor Ischemic Stroke
Stroke, Acute, Cerebrovascular Disorders
Therapy Evaluation in Patients With Minor Stroke and Large Vessel Occlusion
This multicenter registry study, which record the therapy strategy and follows up these acute ischemic stroke (AIS) patients with low NIHSS and large vessel occlusion (LVO), is intended to provide the important data for therapy…
- Conditions
- Stroke, Acute, Cerebrovascular Disorders, Brain Diseases, Central Nervous System Diseases
- Trial name
- TEMPOS (NCT06633809)
- Testing
- Immediate endovascular therapy
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Sir Run Run Shaw Hospital
Minor Stroke, Non-disabling Stroke
Stroke School -Including Physical Exercise, Patient Education and Individual Follow-up Sessions
In a randomized controlled trial the effect of 12 weeks of cross-sectorial physical exercise combined with patient education and individual follow-up session is investigated in patients with minor stroke or non-disabling stroke.
- Conditions
- Minor Stroke, Non-disabling Stroke, Transient Ischemic Attack
- Trial name
- NCT04945174
- Testing
- Cardiorespiratory exercise combined with patient education and individual follow-up sessions
- Where
- 2 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- Herlev Hospital
Ischemic Stroke
Early Antiplatelet for Minor Stroke Following Thrombolysis (EAST)
The current guideline recommends to give antithrombotic treatment 24 hours after intravenous thrombolysis in acute ischemic stroke.
- Trial name
- NCT05193071
- Testing
- Aspirin 100mg; Clopidogrel 300mg
- Where
- 2 sites in China
- Volunteers
- 1,022 people
- Sponsor
- General Hospital of Shenyang Military Region
Ischemia, Stroke
Edoxaban for TIA and Acute Minor Stroke
Transient ischemic attack (TIA) or minor ischemic stroke has a high risk of early recurrent stroke. As the golden standard, aspirin effect modestly on acute ischemic stroke, and slightly increase the risk of intracerebral…
- Conditions
- Ischemia, Stroke, Cerebral Infarction
- Trial name
- NCT02221102
- Testing
- Aspirin, edoxaban
- Where
- China
- Volunteers
- 3,700 people
- Sponsor
- Xijing Hospital
Ischaemic Stroke
Diagnosis and Treatment of Minor Ischaemic Stroke According to the Etiology and Pathogenesis
Negligence or contempt of the etiology and pathogenesis of minor ischaemic stroke in the early diagnosis and effective treatment leads to more than 40-50% of patient with recurrent episodes, and 10% patient died.
- Trial name
- NCT01665729
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Li Haiyan
Ischemic Stroke, Transient Ischemic Attack (TIA)
Ambulatory Stroke Unit Treatment for Elderly Patients
ARTIFICE is a prospective, multicenter, randomized, controlled, exploratory non-inferiority trial evaluating whether an ambulatory stroke unit model (aSU) is non-inferior to conventional inpatient stroke unit care (SU) in…
- Conditions
- Ischemic Stroke, Transient Ischemic Attack (TIA), Retinal Ischemia
- Trial name
- ARTIFICE (NCT07420374)
- Testing
- Ambulatory Stroke Unit Care, Conventional Stroke Unit Care
- Where
- Germany
- Volunteers
- 400 people
- Sponsor
- University Hospital Heidelberg
Stroke, Transient Ischemic Attack (TIA)
Pharmacogenomics in Stroke: Feasibility of CYP2C19 Testing
The purpose of this research study is to explore whether genetic testing can offer a personalized and timely approach to assist physicians in making more informed medication decisions for stroke or high-risk transient ischemic…
- Trial name
- CYP-FAST (NCT06943586)
- Testing
- CYP2C19 Genotype Guided DAPT (dual antiplatelet therapy)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Alabama at Birmingham
Ischemic Stroke
Aspirin Combined With Clopidogrel Versus Intravenous Alteplase for Acute Minor Stroke
An open-label, blinded endpoint, randomized controlled trial that includes patients diagnosed with non-disabling, non-large vessel occlusion, acute minor stroke within 4.5 hours of onset.
- Trial name
- AGREE (NCT05910125)
- Testing
- Aspirin, Clopidogrel, Alteplase
- Where
- China
- Volunteers
- 472 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Ischemic Stroke
Combining Aspirin With Ticagrelor or Cilostazol in Minor Stroke or TIA
Along with the current clinical trial, the efficacy and safety of a 180 mg loading dose of ticagrelor administered within 24 hours of the first-ever minor stroke or TIA compared to 200mg cilostazol were assessed through NIHSS…
- Trial name
- NCT06591390
- Testing
- Ticagrelor 90 MG, Cilostazol 100 MG
- Where
- Egypt
- Volunteers
- 900 people
- Sponsor
- Kafrelsheikh University
Ischemic Stroke
Balloon Angioplasty for Minor Unstable Stroke With IntraCranial Atherosclerosis Stenosis (BAMUS-ICAS)
Intracranial atherosclerotic stenosis (ICAS) is a common cause of stroke, especially in East and South Asia, and is significantly associated with stroke recurrence and early neurological deterioration (END) despite aggressive…
- Trial name
- BAMUS-ICAS (NCT06763458)
- Testing
- Submaximal balloon angioplasty
- Where
- China
- Volunteers
- 100 people
- Sponsor
- General Hospital of Shenyang Military Region
Transient Ischemic Attack, Minor Stroke
Multiple Interventions to Accelerate the Return to the Pre-event Level of Functioning After a TIA and Minor Stroke
The occurrence of a transient ischemic attack (TIA) or a minor stroke is frequently assumed as a temporary and non-disabling event.
- Trial name
- NCT05369637
- Testing
- Cognitive training, Physical exercise, Behavioral: Nutrition education
- Where
- Portugal
- Volunteers
- 70 people
- Sponsor
- Instituto de Saude Publica da Universidade do Porto
Ischemic Stroke, Minor Stroke
Butylphthalide for Long-term Efficacy in Minor Stroke Study
This study is a multicenter, randomized, double-blind, placebo-controlled trial designed to evaluate the long-term efficacy and safety of butylphthalide in patients with minor acute ischemic stroke (BLESS Trial).
- Trial name
- BLESS (NCT07230587)
- Testing
- Butylphthalide
- Volunteers
- 1,200 people
- Sponsor
- Peking Union Medical College Hospital
Ischemic Stroke
Combining Aspirin With Cilostazol or Clopidogrel in Large-vessel Minor Stroke or TIA
Along with the current clinical trial, the efficacy and safety of a 300 mg loading dose of clopidogrel and 300 mg loading aspirin administered within 24 hours of the first-ever large-vessel minor stroke or TIA compared to 200 mg…
- Trial name
- NCT06591351
- Testing
- Cilostazol 100 MG, Clopidogrel
- Where
- Egypt
- Volunteers
- 870 people
- Sponsor
- Kafrelsheikh University
Stroke Ischemic
BREMISS : Brain Resilience Minor Stroke Study
The objective of this clinical trial is to develop, based on patients' initial characteristics (in the first few weeks following the stroke), a predictive model of quality of life more than 4 years after the stroke in patients…
- Trial name
- BREMISS (NCT06995040)
- Testing
- Cerebral MRI without contrast agent injection, saliva sample, Questionnaires
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Brest
Acute Ischemic Stroke
MRSI Evaluation for Minor Stroke With Large Vessel Occlusion
The goal of this observational study is to understand acute anterior circulation large artery occluded minor stroke (LVO-MIS) evolution using magnetic resonance spectroscopic imaging evaluation.
- Trial name
- MINORITY (NCT06457217)
- Testing
- Magnetic resonance spectroscopic imaging
- Where
- China
- Volunteers
- 75 people
- Sponsor
- Shanghai 6th People's Hospital
Ischemic Stroke
Presence of Minor Anti Phospholipid Antibodies in Blood Samples of Ischemic Stroke Patients and Healthy Controls
The investigators expect to find higher levels of both classical and minor antiphospholipid (APL) antibodies among the stroke cases. Furthermore, the investigators expect to find not only classical APLA but also minor antibodies.
- Trial name
- NCT01487746
- Where
- Israel
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Ischemic Stroke, TIA
Cilostazol and Aspirin in Stroke and TIA
This study is a randomized, open-labelled trial. We randomly assigned patients within 24 hours after the onset of minor ischemic stroke or high-risk TIA to combination therapy with cilostazol and aspirin or to clopidogrel plus…
- Trial name
- NCT06522113
- Testing
- Cilostazol, Clopidogrel
- Where
- South Korea
- Volunteers
- 378 people
- Sponsor
- Incheon St.Mary's Hospital
Stroke, Ischemic, Stroke Hemorrhagic
Lifestyle Counselling as Secondary Prevention in Patients With Minor Stroke and Transient Ischemic Attack
Interventions to improve health behaviour in patients with resent acute stroke are not well established. This study will evaluate the feasibility and effect of an early initiated counselling intervention targeting smoking…
- Conditions
- Stroke, Ischemic, Stroke Hemorrhagic, Transient Ischemic Attack
- Trial name
- NCT03648957
- Testing
- Lifestyle counselling, Usual care, Activity tracker
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Nordsjaellands Hospital
Cerebral Stroke
Conjunctival and Retinal Vascularization and Small Vessel Disease
The purpose of the study is to use a simple photography of conjunctival vessels to search for an association between conjunctival vessels abnormalities and the load of small vessel disease as quantified by MRI in patients with…
- Trial name
- EVACORMA (NCT04447599)
- Testing
- photography of conjunctival vessels
- Where
- France
- Volunteers
- 850 people
- Sponsor
- University Hospital, Toulouse
Ischemic Stroke, Transient Ischemic Attack
Liraglutide in Acute Minor Ischemic Stroke or High-risk Transient Ischemic Attack Patients With Type 2 Diabetes Mellitus
The purpose of this study is to assess the safety and efficacy of glucagon-like peptide-1 (GLP-1) analogue liraglutide in the treatment of acute minor stroke (National Institute of Health stroke scale, NIHSS ≤ 3) or high-risk…
- Conditions
- Ischemic Stroke, Transient Ischemic Attack, Type 2 Diabetes Mellitus
- Trial name
- LAMP (NCT03948347)
- Testing
- Liraglutide
- Where
- China
- Volunteers
- 1,708 people
- Sponsor
- First Affiliated Hospital of Jinan University