Clinical trials: Mitral Valve Stenosis
Valvular Heart Disease
Age and Sex-Specific PREValence of AcqUirEd VALVular Heart DiseasE
The PREVUE-VALVE study will establish reliable, population-based estimates of Valvular Heart Disease (VHD) prevalence among older Americans and allow for the development and validation of several innovative tools to aid in the…
- Trial name
- PREVUE-VALVE (NCT05357404)
- Where
- United States
- Volunteers
- 2,870 people, healthy volunteers welcome
- Sponsor
- Cardiovascular Research Foundation, New York
Mitral Valve Stenosis
Mitral Valve Area Assessment: Comparison With Transthoracic Echocardiography and Magnetic Resonance Imaging
To compare mitral valve area in rheumatic mitral valve stenosis with cardiac magnetic resonance imaging and conventional transthoracic echocardiography.
- Trial name
- NCT00654472
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Florence Nightingale Hospital, Istanbul
Valvular Heart Disease
Home-Based Cardiac Rehabilitation Using a Novel Mobile Health Exercise Regimen Following Transcatheter Heart Valve Interventions
The vast majority of cardiac rehabilitation eligible individuals do not participate in center based cardiac rehabilitation (CBCR).
- Trial name
- HOMERUNHITTER (NCT06077201)
- Testing
- HBCR hands-off, HBCR interactive
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Vanderbilt University Medical Center
Mitral Valve Reconstruction
Neurologic Outcome After Mitral Valve Surgery
Reconstructive mitral valve surgery is increasingly done by minimal- invasive anterolateral thoracotomy technique in contrast to surgical approach by sternotomy.
- Trial name
- NCT03798015
- Testing
- mitral valve surgery
- Where
- Switzerland
- Sponsor
- University Hospital, Basel, Switzerland
Valvular Heart Diseases, Valvular Heart Disease Stenosis and Regurgitation
ECG and CXR for Predicting Cardiovascular Diseases
This retrospective multicenter cohort study aims to develop and validate an artificial intelligence model integrating electrocardiography (ECG) and chest radiography (CXR) to predict future progression of regurgitant valvular…
- Conditions
- Valvular Heart Diseases, Valvular Heart Disease Stenosis and Regurgitation, Regurgitation, Aortic Valve, Regurgitation, Mitral
- Trial name
- NCT07573852
- Where
- China
- Volunteers
- 116,380 people, healthy volunteers welcome
- Sponsor
- Shanghai Zhongshan Hospital
Mitral Valve Stenosis
Late Clinical Outcomes of Percutaneous Mitral Commissurotomy in Patients With Mitral Stenosis
In this retrospective cohort study, out of 220 patients who had undergone successful PTMC between 2006 and 2018, the clinical course of 186 patients could be successfully followed.
- Trial name
- NCT04112108
- Testing
- PTMC
- Where
- Iran
- Volunteers
- 220 people
- Sponsor
- Shiraz University of Medical Sciences
Mitral Stenosis
Impact of Percutaneous Transvenous Mitral Commissurotomy on The Left Atrial Appendage Function in Patients With Mitral Stenosis.
Evaluation of the effect of PTMC on LAA function by TEE at least one month after the procedure and its effectiveness in prevention of thrombi formation and cerebrovascular complications.
- Trial name
- NCT06340997
- Testing
- Transesophageal echocardiography
- Volunteers
- 25 people
- Sponsor
- Assiut University
Hypertrophic Obstructive Cardiomyopathy
Transapical Beating-Heart Septal Myectomy in Patient With Hypertrophic Obstructive Cardiomyopathy: a Multi-Center Study
The primary purpose of this study is to evaluate the feasibility, the safety and the efficacy of the transapical beating-heart septal myectomy for the treatment of hypertrophic obstructive cardiomyopathy.
- Trial name
- NCT05957419
- Testing
- Transapical beating-heart septal myectomy
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Xiang Wei
Valve Disease, Aortic, Mitral Regurgitation (MR)
DELINEATE-Prospective
Heart disease is the leading cause of death in the United States, and echocardiography (or "echo") is the most common way doctors look at the heart.
- Conditions
- Valve Disease, Aortic, Mitral Regurgitation (MR), Aortic Stenosis, Valvular Heart Disease
- Trial name
- DELINEATE (NCT07197736)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Columbia University
Mitral Valve Disease, Mitral Regurgitation
Clinical Investigation for the Foldax Tria Mitral Valve- India
The purpose of this study is to conduct a clinical investigation of the Foldax Tria Mitral Valve to collect evidence on the device's safety and performance.
- Conditions
- Mitral Valve Disease, Mitral Regurgitation, Mitral Stenosis, Mitral Valve Insufficiency
- Trial name
- NCT06191718
- Testing
- Mitral Valve Replacement
- Where
- 10 sites in India
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Foldax, Inc
Aortic Stenosis, Mitral Regurgitation
Evaluating Infrasonic Hemodynography
This comparative diagnostic accuracy study will determine the accuracy of a noninvasive wearable infrasonic sensor to detect the mechanical, electrical, and hemodynamic function of the cardiovascular system.
- Conditions
- Aortic Stenosis, Mitral Regurgitation, Pulmonary Hypertension, Heart Failure, Systolic
- Trial name
- NCT04636892
- Testing
- MindMics earbud
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Scripps Health
Development of Standardized Assessment TAVI and MitraClip Procedures by Echocardiography, Aortic Stenosis
Examination of Valve Insufficiency Before and After MitraClip or TAVI Procedure by 3D Echocardiography Compared to MRI
Aim of the study is the definition of criteria for a standardized assessment of heart function by 3D echocardiographic procedures.
- Conditions
- Development of Standardized Assessment TAVI and MitraClip Procedures by Echocardiography, Aortic Stenosis, Mitral Valve Insufficiency
- Trial name
- 3D_TTE_TAVI (NCT01966146)
- Testing
- Echography GE Healthcare Vivid E9
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- RWTH Aachen University
Coronary Artery Disease, Aortic Valve Stenosis
Comparative Analysis of the Microcirculation During Cardiac Surgery With Minimal Invasive Versus Conventional Extracorporeal Circulation
The aim of the proposed study is to evaluate microcirculatory alterations in patients undergoing open heart surgery with minimal invasive versus conventional extracorporeal circulation.
- Conditions
- Coronary Artery Disease, Aortic Valve Stenosis, Mitral Disease
- Trial name
- NCT05479188
- Testing
- Sublingual microscopy
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- Aristotle University Of Thessaloniki
Mitral Stenosis
French National Observatory of Percutaneous Mitral Commissurotomy
The aim of this study is to validate prospectively the predictive score of late results about a diverse population recruited in France and to evaluate the contribution in predicting the outcome of the PMC scanner to study the…
- Trial name
- CALCIMIT (NCT02783248)
- Where
- France
- Volunteers
- 301 people
- Sponsor
- French Cardiology Society
Mitral Valve Insufficiency, Aortic Stenosis Senile
Clinical and Geriatric Assessment in Elderly Patients Before and After TAVI or MitraClip Positioning
Since October of 2014, the Policlinico Umberto I Hospital has an "Heart Team", a group of selected specialists with the task of assessing and identifying eligible patients for valvular aortic transcatheter implantation (TAVI) or…
- Trial name
- NCT03145376
- Testing
- geriatric assessment
- Where
- 2 sites in Italy
- Volunteers
- 100 people
- Sponsor
- University of Roma La Sapienza
Heart Valve Diseases or Prosthesis, Aortic Valve Stenosis
Comparison of Early Postoperative Outcomes Between Minimally Invasive Valve Surgery Via Right Thoracotomy and Conventional Valve Surgery Via Sternotomy.
This randomized controlled trial aims to compare early postoperative outcomes between Minimally Invasive Valve Surgery (MIVS) via right thoracotomy and Conventional Valve Surgery via median sternotomy in patients undergoing…
- Conditions
- Heart Valve Diseases or Prosthesis, Aortic Valve Stenosis, Aortic Valve Insufficiency, Valvular Heart Disease Stenosis and Regurgitation (Diagnosis)
- Trial name
- NCT07251660
- Testing
- Minimally Invasive Valve Surgery, Conventional Valve Surgery
- Volunteers
- 32 people
- Sponsor
- Chaudhry Pervaiz Elahi Institute of Cardiology
Mitral Valve Disease
Management and Clinical Outcomes of Patients With Severe Mitral Valve Disease Not Suitable for Surgery
The objective of this study is to collect in a prospective registry all cases of French patients undergoing an assessment for percutaneous treatment of mitral valve disease on a native valve or due to deterioration after surgical…
- Trial name
- MITRAGISTER (NCT02925819)
- Where
- 3 sites in France
- Volunteers
- 500 people
- Sponsor
- French Cardiology Society
Rheumatic Heart Disease, Acute Rheumatic Fever
Rheumatic Heart Disease in Peru: Prevalence and Cardiovascular Outcomes Among Schoolchildren
Rheumatic heart disease remains a major challenge in low and middle income countries. Early detection of clinically silent valvular lesions by screening echocardiography allows timely implementation of secondary antibiotic…
- Trial name
- NCT02353663
- Testing
- Echocardiography
- Where
- 2 sites in Peru, Switzerland
- Volunteers
- 1,023 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Cardiac Disease, Pulmonary Disease, Healthy Volunteer
Exploratory Study of the Diagnostic Potential of an Innovative Thoracic Vibration Analysis Technique
Heart and lung disease are two major causes of hospitalisation and mortality in France (4-8). Together, these two diseases affect several million people in France, either acutely or chronically.
- Conditions
- Cardiac Disease, Pulmonary Disease, Healthy Volunteer, Aortic Stenosis Disease, Mitral Regurgitation
- Trial name
- AIRFORCE2 (NCT06661200)
- Testing
- SMC signal recording
- Where
- France
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Isolated Aortic Stenosis, Mitral Regurgitation
A Study to Evaluate a Computerized Stethoscope Called ©Voqx to Diagnose Heart Disease
The purpose of this study is to determine whether recording heart sounds with an acoustic stethoscope, combined with artificial intelligence (computer information), will show similar abnormalities to an echocardiogram or cardiac…
- Trial name
- NCT04960280
- Testing
- ©VoqX stethoscope
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Mayo Clinic