Clinical trials: Mobility
Obesity & Overweight, Mobility Disability
Proof-of-Concept Study Evaluating Total Body Weight, Physical Function & Safety of Enobosarm in Patients Treated With GLP-1 Receptor Agonist, for Weight Loss
The primary objective of this study is to assess the effect of enobosarm on total body weight
- Conditions
- Obesity & Overweight, Mobility Disability, HOMA-IR
- Trial name
- PLATEAU (NCT07446998)
- Testing
- Enobosarm, Semaglutide (Wegovy) weekly injection
- Where
- 13 sites in United States
- Volunteers
- 239 people
- Sponsor
- Veru Inc.
PHYSIOLOGICAL PHENOMENA, Homeostasis
Truway Whole-Body Digital Twin and Physiologic Resilience Study (TRU-OMNIBODY)
TRU-OMNIBODY is a prospective observational study designed to develop and independently validate a research-only whole-body digital twin.
- Conditions
- PHYSIOLOGICAL PHENOMENA, Homeostasis, Physical Functional Performance, Cardiorespiratory Fitness
- Trial name
- TRU-OMNIBODY (NCT07805044)
- Testing
- Standardized Physiologic Resilience Challenge, Multimodal Whole-Body Physiologic Monitoring, Research-Only Whole-Body Digital Twin Analysis
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Truway Health, Inc.
Hip Fractures, Mobility Limitation
Validation of the French Version of the New Mobility Score (NMS)
The incidence of hip fractures in France is 50,000 cases per year among women and 16,000 among men, with a 1-year mortality rate of 20-24%. After a fracture, 10-30% of patients become functionally dependent.
- Conditions
- Hip Fractures, Mobility Limitation, Independence, Autonomy
- Trial name
- MOB-SCORE (NCT07622095)
- Testing
- Questionnaires
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Hospices Civils de Lyon
Knee Osteoarthritis, Falls
Effects of Tele Rehabilitation vs Onsite Rehabilitation on Balance, Mobility, and Risk of Fall Among Geriatric Population With Knee Osteoarthritis
This randomized controlled trial aims to determine the effects of telerehabilitation versus onsite rehabilitation on balance, mobility, and risk of fall among geriatric patients with knee osteoarthritis (KOA).
- Conditions
- Knee Osteoarthritis, Falls, Balance Impairment, Mobility Limitation
- Trial name
- NCT07798973
- Testing
- Telerehabilitation, Onsite Rehabilitation
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Ibadat International University, Islamabad
Urinary Incontinence, Limited Mobility
An Observational, Multinational, In Hospital Evaluation of Catheter Utilization Rates in Female Patients Using Indwelling Urinary Catheters and the PureWick™ Flex Female External Catheter Across Europe and the Middle East
Urinary catheterization is commonly used in hospitalized patients for the management of urinary incontinence, immobilization, and monitoring of urinary output.
- Trial name
- REDUCE (NCT07798128)
- Testing
- PureWick™ Flex Female External Catheter (FFEC), Indwelling Urinary Catheter (IUC)
- Volunteers
- 240 people
- Sponsor
- Becton, Dickinson and Company
Old Adults, Sleep Quality
Kava Aging and Mobility Study
The goal of this clinical trial is to learn if AB-free kava works to improve mobility and physical function in older adults with sleep difficulties. It will also learn about the safety of AB-free kava.
- Conditions
- Old Adults, Sleep Quality, Kava, Mobility Impairment
- Trial name
- NCT07219186
- Testing
- AB-free kava
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- University of Florida
Nurse-Patient Relations, Implementation Research
Nurses in the Lead - Nursing Leadership and Autonomy in Function Focused Care in Hospital
The goal of this prospective before-after study (observational) is to implement Function Focused Care in Hospital (FFCiH), paying specific attention to the role of nurses and how they can take the leadership and autonomy in the…
- Conditions
- Nurse-Patient Relations, Implementation Research, Physical Inactivity, Physical Activities
- Trial name
- NCT06878820
- Testing
- Function Focused Care
- Where
- 3 sites in Netherlands
- Volunteers
- 425 people
- Sponsor
- Leiden University Medical Center
Hip Replacement Surgery, Hip Replacement, Total
OPPOSED (anteriOr hiP arthroPlasty regiOnal aneSthEsia stuDy) Study
Main indications for total hip arthroplasty (THA) are degenerative osteoarthritis of the coxofemoral joint, osteonecrosis of the hip, congenital disorders such as dysplasia and inflammatory arthritis.
- Conditions
- Hip Replacement Surgery, Hip Replacement, Total, Hip Pain, Hip Arthroplasty
- Trial name
- NCT07017192
- Testing
- SIFI Block, ESP block
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Immobility Syndrome, Deep Venous Thrombosis
Bedside Bike Early Mobilization Program for Inpatients
Hospital immobility leads to serious complications including muscle loss, weakness, delirium, pressure ulcers, and blood clots. Despite being medically stable, hospitalized patients spend over 90% of their time in bed due to…
- Conditions
- Immobility Syndrome, Deep Venous Thrombosis, Delirium, Hospital Acquired Condition
- Trial name
- BB-STEP (NCT07281638)
- Testing
- Bedside Bike
- Volunteers
- healthy volunteers welcome
- Sponsor
- Indiana University
Osteoarthritis (OA), Osteoarthritis (OA) of the Hip
Evaluation of Choose to Move Replacement Ready (CTM-RR)
Choose to Move (CTM) is a 3-month, choice-based health-promoting program for low active older adults being scaled-up across British Columbia (BC), Canada.
- Conditions
- Osteoarthritis (OA), Osteoarthritis (OA) of the Hip, Osteoarthritis (OA) of the Knee, Total Knee Anthroplasty
- Trial name
- CTM-RR (NCT07696650)
- Testing
- Choose to Move Replacement Ready
- Where
- Canada
- Volunteers
- 210 people
- Sponsor
- University of British Columbia
Down Syndrome, Balance Impairment
Vestibular Stimulation Versus Foot Intrinsic Muscle Exercises in Children With Down Syndrome
This study will compare the effects of vestibular stimulation exercises and foot intrinsic muscle exercises on balance and functional mobility in children with Down syndrome aged 4-15 years.
- Conditions
- Down Syndrome, Balance Impairment, Functional Mobility
- Trial name
- VESTIB-FIME (NCT07778654)
- Testing
- Vestibular Stimulation Exercises, Foot Intrinsic Muscle Exercises
- Volunteers
- 48 people
- Sponsor
- Shalamar Institute of Health Sciences
Physical Deconditioning, Mobility Decline
Development of a Power Training Program to Improve Mobility in Older Veterans
The overall purpose of this study is to develop a power training intervention in partnership with Veterans participating in Gerofit and to evaluate the program's acceptability, feasibility, and preliminary participant outcomes…
- Trial name
- NCT07210645
- Testing
- Gerofit Power Training, Gerofit Standard of Care
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- VA Office of Research and Development
Hip Fracture Surgery, Mobility Limitation
Feasibility of a Co-designed Mobility Intervention After Hip Fracture Surgery
This clinical study examines whether a co-designed mobility intervention can be delivered in routine hospital care after hip fracture surgery.
- Conditions
- Hip Fracture Surgery, Mobility Limitation, Postoperative Rehabilitation
- Trial name
- HIP-ME-UP (NCT07561164)
- Testing
- HIP-ME-UP mobility intervention
- Where
- Denmark
- Volunteers
- 25 people
- Sponsor
- Hvidovre University Hospital
Aging, Walking
Effects of a Powered Lower-Limb Exoskeleton on Walking Performance in Older Adults
The goal of this clinical trial is to learn whether a powered wearable lower-limb exoskeleton can improve walking performance in independently ambulatory older adults aged 65 to 75 years.
- Conditions
- Aging, Walking, Physical Function, Mobility Limitation
- Trial name
- E-WALK (NCT07633093)
- Testing
- Powered Lower-Limb Exoskeleton
- Where
- China
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Hunan Normal University
Mobility on the Way to Work and Health-related Outcomes
Promoting Sustainable and Active Mobility Among Employees and Students
The aim of the study is to assess health data (heart rate variability, blood pressure, blood glucose, particulate matter pollution) and travel characteristics (length, duration and type of commute) on the way to and from work…
- Trial name
- DiNaMo-active (NCT06493006)
- Where
- Germany
- Volunteers
- 367 people, healthy volunteers welcome
- Sponsor
- Hannover Medical School
Mobility Disability, Walking Difficulty
Impact of Loss Aversion Messaging and Anticipated Regret for Inaction on Exercise Adherence in Older Adults
The goal of this clinical trial is to learn if messages focused on not losing the functional benefits of exercise can help older adults with walking difficulty continue to exercise regularly.
- Trial name
- NCT07540052
- Testing
- Brief Daily At-Home Strength Training Program, Loss Aversion Messaging, Standard Adherence Reminder Messaging
- Where
- United States
- Volunteers
- 148 people
- Sponsor
- Milton S. Hershey Medical Center
Mobility Limitations, Community-dwelling Older Adults
Smart Nursing AI Agent for Health Self-Management
This study aims to develop and evaluate a smart nursing AI agent to support health self-management among middle-aged and older patients, and further to examine its effectiveness in home care and health self-management.
- Conditions
- Mobility Limitations, Community-dwelling Older Adults, Middle-aged and Older Adults
- Trial name
- NCT07761663
- Testing
- Smart Nursing AI Agent
- Where
- Taiwan
- Volunteers
- 102 people
- Sponsor
- National Yang Ming Chiao Tung University
Impaired Mobility, Impaired Balance
Usability Evaluation of the Safer Seat
This is an initial usability assessment of a vehicle Seat Transfer device, the Safer Seat. The study will involve target end users (individuals with mobility impairments) trialing the Safer Seat and providing feedback via the…
- Trial name
- NCT07011446
- Testing
- Safer Seat Usability Trial
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Julie Faieta
Spinal Cord Injury, Spinal Cord Injury Subacute
Spinal Stimulation With Gait Training to Improve Lower Limbs Motor Recovery in Spinal Cord Injury
Spinal cord injury (SCI) often results in partial or complete loss of movement. In the subacute phase (< 6 months), the central nervous system shows increased potential for neuroplasticity, making it more responsive to…
- Conditions
- Spinal Cord Injury, Spinal Cord Injury Subacute, Locomotion, Gait Disorder, Sensorimotor
- Trial name
- CIMELocomotion (NCT07375745)
- Testing
- Protocol 2: Gait training combined with an effective tSCS
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Centre for Interdisciplinary Research in Rehabilitation of Greater Montreal
Myocardial Infarction, Stroke
Women's Health Initiative Strong and Healthy Study
The WHISH trial applies state-of-the science behavioral principles and currently available technologies to deliver a physical activity intervention without face-to-face contact to ~25,000 older U.S. women expected to consent.
- Conditions
- Myocardial Infarction, Stroke, Cardiovascular Mortality, Hip Fractures
- Trial name
- WHISH (NCT02425345)
- Testing
- Physical Activity
- Volunteers
- 49,331 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center