Clinical trials: Mobility Impairments
Parkinson Disease, Freezing of Gait
Use of CereGate Therapy for Freezing of Gait in PD
A Multi-Center, Controlled Study to Evaluate Use of CereGate Therapy to Reduce Freezing of Gait in Participants Diagnosed with Parkinson's Disease.
- Conditions
- Parkinson Disease, Freezing of Gait, Deep Brain Stimulation
- Trial name
- NCT05292794
- Testing
- CereGate Software; BSN cDBS Programmer; BSN Burst Programmer
- Where
- 7 sites in United States
- Volunteers
- 41 people
- Sponsor
- CereGate Inc.
Cerebral Small Vessel Disease
Neural Correlates (EEG and fMRI) of Gait in Small Vessel Disease
What is the purpose of this study? This observational study is being done to understand how cerebral small vessel disease (SVD) affects walking and balance.
- Trial name
- doesn't exist (NCT07372937)
- Testing
- No Intervention: Observational
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Mobility Limitation, Cognitive Impairment
Combining tDCS and Neurorehabilitation to Treat Age-related Deficits of Mobility and Cognition: UPfront Walking Study
Loss of mobility and cognitive ability are serious conditions that threaten the independence of older adults. The objective of this study is to initiate a line of research to develop a novel therapeutic intervention to enhance…
- Trial name
- NCT03122236
- Testing
- Neurorehabilitation of Standard Walking, Neurorehabilitation of Complex Walking, Active Transcranial Direct Current Stimulation (Active tDCS)
- Where
- 3 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Florida
Aging
Safety and Feasibility of Dasatinib and Quercetin in Adults at Risk for Alzheimer's Disease
The purpose of this pilot study is to demonstrate the safety and feasibility of administering intermittent doses of Dasatinib and Quercetin (D+Q) in older adults at risk of Alzheimer's disease (AD).
- Trial name
- STAMINA (NCT05422885)
- Testing
- Dasatinib, Quercetin
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Lewis Lipsitz
Hip Fractures, Mild Cognitive Impairment
Reducing Fall Risk Post Hip Fracture in Mild Cognitive Impairment
Hip fracture is recognized as one of the most serious consequences of osteoporosis, less than half regain pre-fracture independence. 95% of all hip fractures in older adults are due to falls.
- Trial name
- NCT04748354
- Testing
- Otago Exercise Program, Usual Care
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of British Columbia
Traumatic Lower Limb Amputation, Fatigue
Effect of Adding Progressive Muscle Relaxation to Physical Therapy Program on Fatigue, Mobility and Stress Among Individuals With Traumatic Lower Limb Amputation in the Gaza Strip
Lower limb amputation is a life-altering condition with profound physical and psychological consequences, including fatigue, impaired mobility, stress, and asymmetrical weight-bearing.
- Conditions
- Traumatic Lower Limb Amputation, Fatigue, Mobility Impairment, Psychological Stress
- Trial name
- PMR-AMP (NCT07139145)
- Testing
- Progressive Muscle Relaxation + Standard Physiotherapy, Standard Physiotherapy
- Where
- Palestinian Territories
- Volunteers
- 60 people
- Sponsor
- Marah Radi
Low Vision, Aged
Evaluation of a Standardised Orientation and Mobility Training in Older Adults With Low Vision
The purpose of this study is: 1. to develop a standardised orientation and mobility training (O\&M-training) in the use of an identification/symbol cane by older adults with low vision, and; 2.
- Trial name
- NCT00946062
- Testing
- orientation and mobility training
- Where
- 3 sites in Netherlands
- Volunteers
- 190 people
- Sponsor
- Maastricht University Medical Center
Aging Disorder
Physical Impairments in Elderly Individuals
There are no studies in the literature reporting the dyspnea, posture, strength, physical activity, functional mobility and balance in elderly individuals.
- Trial name
- NCT06267625
- Testing
- Physical Evaluations of individuals
- Where
- Turkey (Türkiye)
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Izmir Democracy University
Multiple Sclerosis, Balance Impairment, Gait Disorders, Fatigue
The Effect of Task-Oriented Training and Virtual Reality Training on Balance, Gait and Fatigue in Individuals With Multiple Sclerosis
Introduction: Multiple sclerosis (MS) is a chronic disease of the central nervous system. Task-focused training is an approach that relies on multiple repetitions of motor performance.
- Conditions
- Multiple Sclerosis, Balance Impairment, Gait Disorders, Fatigue, Multiple Sclerosis Bening, Multiple Sclerosis Relapsing Remitting
- Trial name
- NCT07000968
- Testing
- Virtual Reality Training Group, Task-Oriented Training Group, Conventional Training Group
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Inonu University
Multiple Sclerosis, Gait Disorders, Neurologic
Investigating the Effects of Wearable Robotic Exoskeleton for Improving Mobility and Cognition in Persons With MS
The purpose of this research study is to evaluate the usefulness of a wearable robotic exoskeleton device (Ekso-GT), to improve learning and memory, and gait therapy in persons with walking disability due to Multiple Sclerosis.
- Conditions
- Multiple Sclerosis, Gait Disorders, Neurologic, Motility Disorder, Cognitive Impairment
- Trial name
- NCT04855825
- Testing
- Robotic Exoskeleton Rehabilitation, Conventional Gait Therapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Kessler Foundation
Mild Cognitive Impairment (MCI), Exercises
High-Amplitude Functional Exercises in Older Adults With Mild Cognitive Impairment
This study will investigate the effects of dual-task-based high-amplitude functional exercises on balance and functional mobility in older adults with mild cognitive impairment.
- Trial name
- NCT07762235
- Testing
- Dual-Task-Based High-Amplitude Functional Exercise Program, Traditional Balance and Mobility Exercise Group
- Volunteers
- 36 people
- Sponsor
- Istinye University
Cognitive Impairment
Cognitive Sensorimotor Training With Whole Body Vibration for Cognitive Impairment
Aging is associated with cognitive decline, ranging from normal to mild cognitive impairment or dementia. This leads to physical and cognitive impairment, which are risk factors for loss of autonomy therefore physical and…
- Trial name
- NCT06927492
- Testing
- Cognitive Sensorimotor training along with whole body vibration, Cognitive Sensorimotor training
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Riphah International University
Cardiovascular Diseases
Dysphagia in Cardiac Surgical Patients_
The proposed study seeks to determine the incidence of dysphagia and vocal fold mobility impairment (VFMI) in individuals undergoing cardiovascular surgical procedures.
- Trial name
- NCT04496986
- Testing
- Fiberoptic Endoscopic Evaluation of Swallowing, Simultaneous FEES and Videofluoroscopy instrumental swallowing exam, Voluntary Cough Peak Expiratory Flow (PEF) Testing
- Sponsor
- University of Florida
Cognitive Impairment, Dementia
Older Adults With Cognitive Impairment Doing Sit to Stands, Walking in Transitional Care Programs: A Feasibility Study
The goal of this intervention study is to test the effects of a nurse-led mobility intervention (known as the OASIS Walking Intervention (Older Adults performing Sit to Stands and Walking Intervention)) in older adults with…
- Conditions
- Cognitive Impairment, Dementia, Delirium, Functional Decline
- Trial name
- OASIS (NCT06150339)
- Testing
- OASIS Walking Intervention
- Where
- 2 sites in Canada
- Volunteers
- 6 people
- Sponsor
- University Health Network, Toronto
Cerebral Palsy, Arthrogryposis
Effects of Power Mobility on Young Children With Severe Motor Impairments
The purpose this study is to determine the effects of power mobility on the development and function of young children of young children whose severe physical disabilities limit their exploratory behaviors and may unnecessarily…
- Conditions
- Cerebral Palsy, Arthrogryposis, Spinal Muscular Atrophy, Other Central Nervous System or Musculoskeletal Disorders
- Trial name
- NCT01028833
- Testing
- Power mobility
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- University of Oklahoma
Lower Limb Amputation, Prosthesis Users
Dual-Task Balance Training in Traumatic Lower-Limb Prosthesis Users
This randomized controlled trial will evaluate the effectiveness of dual-task balance training on balance, mobility, and mental health among traumatic lower-limb prosthesis users in the Gaza Strip.
- Conditions
- Lower Limb Amputation, Prosthesis Users, Balance Impairment, Mobility Limitations
- Trial name
- DTBT-LLA (NCT07706452)
- Testing
- Dual-Task Balance Training, Standard Rehabilitation
- Where
- Palestinian Territories
- Volunteers
- 63 people
- Sponsor
- Al-Azhar University - Gaza
Mobility Limitation, Balance Impairment
TIME™ at Home Feasibility Study: Evaluation of a Virtually Delivered, Community-based, Task-oriented Exercise Program
Balance and mobility limitations can lead to increased difficulty with everyday function and increased dependence on caregivers.
- Trial name
- NCT05369741
- Testing
- TIME™ at Home
- Where
- 2 sites in Canada
- Volunteers
- 20 people
- Sponsor
- University of Toronto
Chronic Ischemic Stroke
CC-101 (f/k/a NR1) Neural Stem Cell Transplantation for Adults With Chronic Ischemic Stroke
The suNR1se II Study is a Phase 2b randomized, controlled, multi-center clinical trial evaluating the efficacy and safety of stereotactic intracerebral administration of CC-101 (f/k/a NR1), an investigational allogeneic neural…
- Trial name
- suNR1se II (NCT07709845)
- Testing
- CC-101 (f/k/a NR1) Intracerebral Transplantation, Tacrolimus
- Volunteers
- 36 people
- Sponsor
- Clarion Cells, Inc.
Fall Prevention, Functional Independence
A Strategy for Fall Prevention in Aging Women
This retrospective study examined the effects of a 12-month training program on physical performance and functional ability in healthy older women.
- Conditions
- Fall Prevention, Functional Independence, Balance Impairment
- Trial name
- STABLE-WOMEN (NCT07481409)
- Testing
- Multicomponent and Stability Exercise Program
- Where
- Serbia
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Novi Sad
Charcot Marie Tooth Disease (CMT), Pes Cavovarus
Walking Function Outcomes Following Surgical Correction With Rehabilitation Versus Physical Therapy Alone in Charcot-Marie-Tooth Disease: A Bidirectional Cohort Study
The goal of this study is to compare changes in walking ability in people with Charcot-Marie-Tooth disease (CMT) who receive two different treatment approaches for foot deformities that affect walking.
- Conditions
- Charcot Marie Tooth Disease (CMT), Pes Cavovarus, Surgery, Exercise Training
- Trial name
- CMT-WALK (NCT07432035)
- Testing
- Functional Surgery plus Rehabilitation, Physical Exercise
- Volunteers
- 200 people
- Sponsor
- Peking University Third Hospital