Clinical trials: Moderate Sedation
Undesired Intrauterine Pregnancy, First Trimester Pregnancy
Trial Comparing Intravenous and Oral Moderate Sedation for First Trimester Surgical Abortions
In the United States, the majority of first-trimester surgical abortions are performed in outpatient clinics that utilize a wide variety of oral and intravenous regimens for pain control.
- Trial name
- NCT01011634
- Testing
- Intravenous moderate sedation versus oral medication
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Sedative Adverse Reaction
Target Controlled Infusion Using Propofol and Remifentanil for Moderate Sedation in Dentistry
The purpose of this university study is to evaluate the use of an advanced dental sedation technique involving two syringe-type pumps called Target Controlled Infusion (TCI) pumps.
- Trial name
- NCT03995134
- Testing
- Propofol and Remifentanil administered by TCI pump
- Where
- 2 sites in Canada, New Zealand
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Conscious Sedation
Effects of Oral Midazolam in Comparison Promethazine With Nitrous Oxide for Uncooperative Children
The purpose of this study is to compare the safety and efficacy of sedation using orally administered midazolam and promethazine with nitrous oxide/oxygen in uncooperative children receiving dental treatments.
- Trial name
- NCT01118884
- Testing
- Promethazine
- Where
- Iran
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University
Conscious Sedation, Patient Satisfaction
Use of Ketamine for Conscious Sedation in Flexible Bronchoscopy
In this study, the investigators plan to conduct a single blinded randomized controlled trial in the Pulmonary Service to demonstrate the efficacy of ketamine and its utility in moderate sedation.
- Conditions
- Conscious Sedation, Patient Satisfaction, Ketamine
- Trial name
- NCT06181188
- Testing
- Ketamine, Midazolam, Fentanyl
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Brooke Army Medical Center
Conscious Sedation
Intranasal Sedation With Dexmedetomidine
For patients with eye surgery and shorter surgery, sedation is a well-established method in preserved consciousness and has been successfully used for several years. We have also developed and published a valid protocol (1).
- Trial name
- NCT03251222
- Testing
- Dexmedetomidine
- Where
- Slovenia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Dental Anxiety, Dental Fear
The Effect of Conscious Sedation on Acute Stress
The specific aims of the present study were to evaluate sAA responses to impacted third molar extractions at different time points in the patients under conscious sedation with local anesthesia and to examine the relationship…
- Conditions
- Dental Anxiety, Dental Fear, Tooth Extraction Status Nos
- Trial name
- NCT04207515
- Testing
- Procedures of wisdom tooth removal surgery under conscious sedation, Procedures of wisdom tooth removal surgery under local anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Beykent
Cataract
Conscious Sedation Efficacy of the MKO Melt (Midazolam, Ketamine, Ondansetron)
The investigators hypothesized that the combination of Valium, Tramadol and Zofran is superior to the substantially more expensive MKO melt in patient satisfaction after cataract surgery.
- Trial name
- NCT03653520
- Testing
- Diazepam, Tramadol, Ondansetron
- Where
- United States
- Volunteers
- 651 people, healthy volunteers welcome
- Sponsor
- Avanti Anesthesia
Bronchoscopy, Obstructive Sleep Apnea
Upper Airway Collapsibility Evaluation in Different Sedative Levels by Sleep Endoscopy
The purpose of this study is to evaluate the upper airway collapsibility by sleep endoscopy in different sedative levels. Propofol pump infusion will be used to achieve conscious sedation.
- Conditions
- Bronchoscopy, Obstructive Sleep Apnea, Conscious Sedation
- Trial name
- NCT01100554
- Testing
- Sleep endoscopy
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Bronchoscopy
Narcotrend Versus Bispectral Index Monitoring During Sufentanil-Midazolam Anesthesia for Bronchoscopy
This study was aimed to determine whether narcotrend monitoring was better than bispectral index monitoring during sufentanil-midazolam anesthesia for bronchoscopy under conscious sedation.
- Trial name
- NCT03738137
- Testing
- Narotrend, BIS, Sufentanil
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Guangzhou Institute of Respiratory Disease
Conscious Sedation
Ondansetron Reduce Vomiting Associated With Ketamine PSA
Ondansetron, a commonly used anti-vomiting medication, may reduce the occurrence of vomiting associated with ketamine during procedural sedation in the pediatric emergency department.
- Trial name
- NCT00387556
- Testing
- Ondansetron
- Where
- United States
- Volunteers
- 268 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Glaucoma
Comparing Conscious Sedation to Retrobulbar Block Anesthetics During Trans-scleral Diode Laser
This is a non-inferiority trial with a prospective randomized controlled design assessing patient satisfaction and complications associated with both retrobulbar block anesthetics (current gold standard) and conscious IV sedation…
- Trial name
- NCT03646500
- Testing
- Retrobulbar Block, Remifentanil
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Queen's University
Conscious Sedation
Sedasys Post Approval Study Users Response to System Alarms
The purpose of this study is to evaluate the users' responses to the SEDASYS® System alarms during esophagogastroduodenoscopy (EGD) or colonoscopy.
- Trial name
- NCT02573818
- Testing
- SEDASYS System
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Ethicon Endo-Surgery
Bronchoscopy, Sedation
Safety and Efficacy of Sufentanil Combined With Midazolam in Bronchoscopy Under Conscious Sedation: Retrospective Study
The aim of this study was to determine the safety and efficacy of sufentanil combined with midazolam in bronchoscopy under conscious sedation.
- Trial name
- NCT03890094
- Testing
- Sufentanil
- Where
- China
- Volunteers
- 11,158 people, healthy volunteers welcome
- Sponsor
- Guangzhou Institute of Respiratory Disease
Childrens 0 to 18 Years of Age Who Require Moderate Sedation
Sedation for Brainstem Evoked Auditory Response (BEAR) Testing Using Intravenous Pentobarbital
This is a retrospective chart review study (700 charts from 2002 to 2010)of children from 0 to 18 years of age who have undergone Brainstem Evoked Auditory Response (BEAR)testing using midazolam and pentobarbital protocol for…
- Trial name
- NCT01282112
- Where
- United States
- Volunteers
- 416 people, healthy volunteers welcome
- Sponsor
- Akron Children's Hospital
Anxiety, Pain
Bispectral Index and Clinical Parameters Evaluation in Dental Procedures
BACKGROUND: The degree of consciousness during nitrous oxide use is still a matter of concern for both dentists and anesthesiologists.
- Trial name
- BIS-01 (NCT02671578)
- Testing
- Nitrous Oxide
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Francisco Groppo
Heavy Uterine Bleeding
ThermaChoice III Under Local Sedation in the Office Setting
Investigational study to determine if an endometrial ablation for heavy uterine bleeding, can be tolerated in the office setting without the use of intravenous medication.
- Trial name
- NCT00420264
- Testing
- Uterine Ablation
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Female Pelvic Medicine & Urogynecology Institute of Michigan
Failed Conscious Sedation During Procedure
Controlled Sedation for Cataract Surgery
This study evaluates the surgeon and patient´s satisfaction who undergoes cataract surgery using either dexmedetomidine or remifentanil as sedation
- Trial name
- NCT03401606
- Testing
- remifentanil, Dexmedetomidine
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Fundación Universitaria de Ciencias de la Salud