Clinical trials: Modification
Obesity, Extreme Obesity
Course of Obesity and Extreme Obesity in Adolescents
The rate of adolescent extreme obesity is rapidly rising, and impacting quality of life, psychosocial situation, and health of the affected youth.
- Trial name
- YES (NCT01662271)
- Where
- 5 sites in Germany
- Volunteers
- 429 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Martin Wabitsch
Uterine Fibroids, Adenomyosis
Ovarian Reserve Modification After Lps Hysterectomy With Bilateral Salpingectomy
The aim of this RCT of study is to compare the standard TLH with adnexal preservation with TLH plus prophylactic bilateral salpingectomy (PBS) in terms of ovarian reserve and surgical outcomes
- Conditions
- Uterine Fibroids, Adenomyosis, Pelvic Pain, Pelvic Prolapse
- Trial name
- NCT02086344
- Testing
- PBS, TLH _adnexal preservation
- Where
- Italy
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- University Magna Graecia
Changes in Cerebral Oxygenation During Different Patient Positioning, Coparison of Two Cerebral Oximeters
Comparison of INVOS and FORE SIGHT Cerebral Oximeter
Cerebral oxygenation can be monitored using near infrared spectroscopy. Different devices are available to assess cerebral oxygenation noninvasively. Beach chair position is assumed to influence cerebral oxygenation.
- Trial name
- NCT01275898
- Where
- Germany
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Johannes Gutenberg University Mainz
Health, Children
A Study on the Changes and Prognosis of Intestinal Microbiota and Function in Infants With Food Allergies
Microorganisms maintain a complex interrelationship with the human body, influencing each other. In recent years, people have gradually realized that the formation of the pediatric microecosystem is closely related to the…
- Conditions
- Health, Children, Gut Microbiota
- Trial name
- NCT06854536
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ruijin Hospital
Environmental Exposure, Temperature Change, Body
The Effect of IEQ on Cognition and Health
The goal of this study is to learn about the effect of heat and humidity on cognition and health. The main question[s] it aims to answer are: type of study: interventional participant population: 20-40years, both gender, healthy…
- Conditions
- Environmental Exposure, Temperature Change, Body, Condition, Healthy
- Trial name
- IEQ-HUM (NCT05972187)
- Testing
- Temperature and Humidity
- Where
- Netherlands
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Chronic Kidney Disease
Study of the Influence of Liver Function on Blood Concentrations of Runcaciguat in Participants With Different Degrees of Liver Impairment
Researchers are looking for a better way to treat people with chronic kidney diseases. Before a treatment can be approved for patients to take, researchers do clinical studies to better understand its safety and what happens to…
- Trial name
- NCT04820621
- Testing
- Runcaciguat (BAY1101042)
- Where
- Germany
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Bayer
Healthy, Diet Modification
Uric Acid Metabolism, Endothelial Function and Oxidative Stress in Vegans and Omnivores.
50 vegans and 50 omnivores will be recruited at the Erasme Hospital, Brussels. Hypothesis Relative induced-hyperuricemia by the vegan diet is not associated with impaired endothelial function if vitamin B12 and folic acid levels…
- Trial name
- NCT03849677
- Testing
- Endothelial function and inflammation
- Where
- Belgium
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Erasme University Hospital
Obesity, Diet Modification
Metabolic Impact of Time Restricted Feeding
The investigators are interested in how time-restricted feeding will impact weight, sleep duration and efficacy, and activity levels in obese adults.
- Trial name
- NCT03129581
- Testing
- Dietary Counseling
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Periodontitis
Change in Gingival Volume and Quality of Life Due to Initial Periodontal Therapy in Smokers
The aim of this study is to compare the dimensional changes of the gingiva due to initial periodontal therapy in non-smokers and cigarette smokers and to compare the oral health related quality of life of non-smokers and…
- Trial name
- NCT05719519
- Testing
- Initial periodontal therapy and 3D intraoral scanning
- Where
- Croatia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Rijeka
Retina Disease
Modified P200TE Data Collection
Images will be collected on the modified P200TE
- Trial name
- NCT07796230
- Testing
- imaging device
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Optos, PLC
Covid19, SARS-CoV-2
Changes in Cellular Immune Profile During COVID-19 Infection
Clinical specimens are collected from individuals either recovered from or with active SARS-CoV-2 infection to support process and analytical development for a potential cell-based immunotherapy in preclinical research…
- Trial name
- NCT04470999
- Testing
- Leukapheresis
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Serhat Gumrukcu, MD PhD
Kinesio Taping, Body Temperature Changes
Effect of Kinesio Taping on Lumbar Muscle Temperature
This single-blind, randomized controlled trial aims to investigate the effect of Kinesio Taping (KT) applied to lumbar paravertebral muscles with different tensions (25% and 75%) on local body temperature.
- Trial name
- NCT06760299
- Testing
- %25 tension Kinesio tape, 75% tension Kinesio tape
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Body Temperature Changes, Heat Stress
Exercise Intensity and Heat Responses in Children and Youth
Little is known about how children and youth regulate body temperature during exercise in the heat compared with young adults, including whether differences in whole-body heat exchange contribute to their responses.
- Conditions
- Body Temperature Changes, Heat Stress, Child Development, Heat
- Trial name
- NCT07781592
- Testing
- Low-Intensity Exercise in the Heat, Moderate-Intensity Exercise in the Heat, Vigorous-Intensity Exercise in the Heat
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Sarcopenia, Body Weight Changes
Effects of Resistance Training on Physical Performance, Health and Quality of Life in Elderly (RTCHealth)
Physical exercise is considered an important intervention for promoting well-being and healthy aging. The purpose of the present study was to determine the effects of moderate-to-high intensity resistance training circuit on…
- Conditions
- Sarcopenia, Body Weight Changes, Quality of Life
- Trial name
- RTCHealth (NCT03551132)
- Testing
- Exercise test
- Where
- Spain
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia
Post-osseointegration Biological Failure of Dental Implant, Alveolar Bone Loss
The Influence of Mucosal Tissue Thickness on Soft and Hard Tissue Changes Around Implants
Crestal bone and soft tissue stability around implants is an important issue in implant dentistry. Initial vertical mucosal tissue thickness was shown to be one of the factors having impact on bone stability.
- Trial name
- NCT02580721
- Testing
- Dentsply Astra Tech Implant System EV
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Diabetes Mellitus, Type 1, Diabetic Retinopathy
Choroidal Blood Flow Changes During Dark/Light Transitions in Patients With Insulin-dependent Diabetes Mellitus (IDDM)
There is evidence from a variety of animal studies that choroidal blood flow is under neural control. Recent results in humans indicate that a light/dark transition is associated with a short lasting reduction in choroidal blood…
- Trial name
- NCT00718614
- Testing
- Light will be switched from 0.5µW/cm2/sr to 115µW/cm2/sr.
- Where
- Austria
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Brachial Plexus Birth Palsy, Brachial Plexus Palsy
Evaluation of Pain, Upper Extremity Function, and Social Appearance Anxiety in Adults With Obstetric Brachial Plexus Palsy Who Underwent Shoulder Tendon Transfer Surgery
This observational study aims to evaluate pain and upper extremity function in adults with obstetric brachial plexus palsy who underwent shoulder tendon transfer surgery using the Modified Hoffer technique during childhood.
- Conditions
- Brachial Plexus Birth Palsy, Brachial Plexus Palsy, Brachial Plexus Palsy Due to Birth Trauma
- Trial name
- NCT07655271
- Testing
- Clinical Assessment Battery
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Biruni University
Altered Passive Eruption of Teeth
Gummy Smile and Altered Passive Eruption Prevalence
This observational epidemiological study aims to assess the prevalence of gummy smile and altered passive eruption in a young adult population, with a focus on the second sextant.
- Trial name
- NCT07548398
- Testing
- Clinical assessment
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Corneal Ectasia
Corneal Topographic Changes in Different Grades of OSA
Corneal topographic parameters in different degrees of obstructive sleep apnea
- Trial name
- NCT06347900
- Testing
- Pentacam (corneal topographic changes detection), Polysymnography
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sohag University
Health Behavior
SWAP-MEAT With Athletes for MC-URC: Three Diets on Athletic Performance
This study aims to investigate the impact of two plant-based diets-whole food plant-based (WFPB) and plant-based meat alternatives (PBMA)-vs. an omnivorous diet (Animal) on endurance and muscular strength in recreational athletes.
- Trial name
- NCT06014307
- Testing
- Diet order: PBMA, Animal, Diet order: Animal, PBMA
- Where
- 5 sites in United States, United Kingdom
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Stanford University
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