Clinical trials: Modification
Advance Care Planning
The R4R Advance Care Planning Pilot Study
Affordable housing residents continue to experience multi-faceted insecurity and advance care planning (ACP) challenges even after obtaining secure housing, resulting in significant inequities in quality of care during times of…
- Trial name
- R4RACP (NCT06129149)
- Testing
- Trauma-Informed Care-adapted and Checklist-guided ACP intervention
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Breast Cancer, Obesity
Nutritional Intervention-induced Weight Loss During the Oncological Treatment of Obesity-related Breast Cancer
Obesity could become the first evitable cause of breast cancer in the near future. Due to the relatively slow rate of development in this field, greater efforts must be applied in this area.
- Conditions
- Breast Cancer, Obesity, Weight Change, Body, Epigenetic Disorder
- Trial name
- NUTOBREST (NCT06046755)
- Testing
- Very low calorie ketogenic diet (VLCKD), Group educational intervention program (IGOBE)
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Hospital Clinico Universitario de Santiago
Spinal Injury
MRI-changes in Morphometry and Cerebro Spinale Fluid (CSF) Flow in Spinal Cord Disorders
Understanding the onset and progression of spinal cord disorders is an important aim in clinical neurology. An early diagnosis with consequent therapy might prevent the progression of disability.
- Trial name
- NCT02170155
- Where
- Switzerland
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Vitamin D Deficiency
The Effect of Vitamin D3 Therapy in Post Menopausal Women and Assessment of Changes in Bone Mineral Density After Orally Vitamin D3 Administration
a study design based on vitamin D deficiency in postmenopausal women with low bone density. pre-test for BMD will be done then vitamin D oral supplements will be provided for the period of 3 months.
- Trial name
- NCT05389943
- Testing
- Oral administration of vitamin D3, Vitamin D3 50000 UNT Oral Capsule, milk, Dietary and life style modifications.
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Sargodha
Pain, Traumatic Brain Injury
The NRC Dataset. Developing a Minimum Dataset for Multidisciplinary Rehabilitation: a Modified E-Delphi Study
Several rehabilitation datasets are presently in use for specific patient groups in England. The 'National Clinical Audit of Specialist Rehabilitation for patients with complex needs following major injury' (NCASRI) evaluated…
- Conditions
- Pain, Traumatic Brain Injury, Major Trauma, Multiple Sclerosis
- Trial name
- NCT06726135
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- ThomasCorbett
Liver Fat
Liver, Diet and Genetic Background
PNPLA3 rs738409 (I148M) variant is associated with hepatic liver accumulation and chronic liver diseases including non-alcoholic fatty liver disease.
- Trial name
- LIDIGE (NCT04644887)
- Testing
- Dietary intervention: Healthy diet, Dietary intervention: Control diet
- Where
- Finland
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University of Eastern Finland
Obesity
Study of BMF-650 in Otherwise Healthy Overweight or Obese Adult Participants
A Phase 1, Randomized, Double-Blind, Placebo-Controlled, Single and Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BMF-650 in Otherwise Healthy Overweight or Obese…
- Trial name
- NCT07223216
- Testing
- BMF-650
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Biomea Fusion Inc.
Health Behavior, Physical Activity
Development of a Blended Lifestyle Intervention to Promote Physical Activity, Diet, and Health in Hong Kong Older Adults
This pilot study will provide a theory-based low-cost and easy-to-operate program in the area of healthy lifestyle promotion among community dwelling older adults.
- Conditions
- Health Behavior, Physical Activity, Healthy Diet
- Trial name
- NCT05729087
- Testing
- Blended intervention group
- Where
- Hong Kong
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hong Kong Baptist University
Obesity
Improving Weight Loss Maintenance Through Alternative Schedules of Treatment
This project examines the effects of differing schedules of extended care contact following weight loss treatment in order to prevent weight regain following treatment.
- Trial name
- ImWeL (NCT02487121)
- Testing
- variable interval schedule, self-directed treatment
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Arterial Stiffness
Pulse Wave Velocity and Hemodynamic Response During Anesthesia Induction in Hypertensive Patients
Hypertension is a disease with increasing and serious complications all over the world. In particular, the incidence of hypertension increases with advancing age.
- Trial name
- AS (NCT05155514)
- Testing
- Mobil-O-Graph PWA
- Where
- Turkey (Türkiye)
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Metabolic Health, Weight Loss
A Study to Evaluate the Effect of SlimBiotics Probiotic Formula on Weight Management and Metabolic Health Outcomes
This study is to evaluate the efficacy of a probiotic supplement on weight management and metabolic health. This study will be conducted as a hybrid trial consisting of both in-person visits and virtual assessments.
- Conditions
- Metabolic Health, Weight Loss, Stress, Well-Being, Psychological
- Trial name
- NCT05917314
- Testing
- Slimbiotic Probiotic
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Slimbiotics
Insufficient Keratinized Gingiva
Reharvested Free Gingival Grafts: 3D Shrinkage and Histological Changes
The purpose of this study is to evaluate the dimensional stability of free gingival grafts (FGG) and to investigate the relationship between graft shrinkage (GS) and the histological and biochemical characteristics of grafts…
- Trial name
- NCT07617987
- Testing
- Free gingival graft, Re-harvested free gingival graft
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Biruni University
Stress, Psychological, Depression and/or Anxiety in the Mild-to-moderate Range
Testing Adapted Self-Help Plus (SH+) for Stress and Well-Being in International Students at a U.S. University
The goal of this clinical trial is to learn if an adapted version of Self-Help Plus (SH+), a stress management program developed by the World Health Organization, can reduce stress and improve well-being in international students…
- Conditions
- Stress, Psychological, Depression and/or Anxiety in the Mild-to-moderate Range, Loneliness, Adjustment, Psychological
- Trial name
- NCT07188467
- Testing
- Digitized SH+
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The New School
Anterior Pelvic Tilt, Sprint Kinematics
"Ecological Program Changes Pelvic Kinematics in Soccer Players: Pilot Study on Hamstring Injury Implications"
The present pilot study aimed to investigate whether a 6-week multicomponent intervention, comprising a structural lumbopelvic and sprint technique program, could reduce anterior pelvic tilt in soccer players who regularly…
- Trial name
- NCT06551532
- Testing
- Multicomponent program
- Where
- Spain
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- RX2 Sports and Health
Survivorship, Cancer
Title: Leveraging Technology to Address Health Outcomes of Cancer Survivors
At the end of cancer treatment, many patients are still dealing with symptoms of cancer and side effects of treatment. Many are also left in a surreal mental state with uncertainty regarding the future of their health.
- Conditions
- Survivorship, Cancer, Symptoms and Signs
- Trial name
- POSTHOC (NCT05499663)
- Testing
- POSTHOC app
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Obesity, Gestational Weight Gain
Diet Versus Control Pregnant Barbadian Women Gestational Weight Gain Trial
The researcher will study a group of pregnant Barbadians with BMI at booking of greater than or equal to 35. All of the women will be given leaflets telling them about healthy diets in pregnancy and how to limit weight gain.
- Conditions
- Obesity, Gestational Weight Gain, Obesity, Maternal
- Trial name
- NCT05575414
- Testing
- Didactic dietary sessions, Education Tool
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- The University of The West Indies
Oxygen Metabolism, Muscle Spasticity
Hemodynamic Changes During Dry Cupping Therapy on Low Back Pain
This study aims to investigate the hemodynamic changes during dry cupping therapy (DCT) on low back pain. 50 patients with low back pain as experimental group and 50 healthy people as control group are treated by DCT.
- Trial name
- NCT03816787
- Testing
- Negative pressure therapy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Medical Sciences
Overweight, Physical Capacity
Physical Exercise, Dietary Counseling and Cognitive Behavioral Training as a Combined Intervention to Reduce Weight and Increase Workability in Health Care Workers
The purpose of this study is to evaluate whether a 1 year worksite based life-style intervention can reduce body weight and increase physical capacity and subsequently reduce musculoskeletal disorders and increase workability in…
- Conditions
- Overweight, Physical Capacity, Musculoskeletal Diseases, Work Ability
- Trial name
- FINALE-Health (NCT01015716)
- Testing
- Intervention-group, Control-group
- Where
- Denmark
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Physical Activity, Diet Modification
Dietary Carbohydrate Manipulation and Energy Balance: RCT
This study will investigate how dietary sugar and carbohydrates influence metabolism and health across a 12-week period, with a focus on physical activity.
- Trial name
- NCT03574987
- Testing
- Diet
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Bath
Chronic Kidney Disease
Study of the Influence of Liver Function on Blood Concentrations of Runcaciguat in Participants With Different Degrees of Liver Impairment
Researchers are looking for a better way to treat people with chronic kidney diseases. Before a treatment can be approved for patients to take, researchers do clinical studies to better understand its safety and what happens to…
- Trial name
- NCT04820621
- Testing
- Runcaciguat (BAY1101042)
- Where
- Germany
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Bayer
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