Clinical trials: Modification
Decreased Vascular Flow
Optic Nerve Head Autoregulation During Changes in Arterial Blood Pressure
Constant despite changes in perfusion pressure. It is observed in many vascular beds of the human body to prevent that variations in perfusion pressure are directly transmitted into changes in blood flow.
- Trial name
- NCT01663883
- Testing
- Isometric exercise
- Where
- Austria
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Ozone, Exercise Intensity
Investigating Changes in Responses to Controlled Effective Doses of Ozone at Different Exercise Intensities
The project will look to investigate whether exercise during ozone exposure performed for a shorter duration at a higher intensity is more harmful than exercise performed for a longer duration at a lighter intensity.
- Trial name
- NCT06513754
- Testing
- Ozone, Heavy Intensity, Moderate Intensity
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Michael Koehle
Cognitive Change, Motor Activity
Group Music Practice Enhances Development
This randomized controlled trial shows for the first time that focused musical instrumental practice as compared to traditional sensitization to music provokes multiple transfer effects in the cognitive and sensorimotor domain.
- Trial name
- OC (NCT04200794)
- Testing
- musical instrumental training, sensitization to music
- Where
- Switzerland
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- School of Health Sciences Geneva
Emotions
Ketamine-Induced Brain Changes and Their Modulation by Lamotrigine
This study is firstly designed to investigate acute and delayed effects of a single dose of ketamine on functional brain changes during emotional and cognitive challenges and at rest.
- Trial name
- NCT04156035
- Testing
- Lamotrigine, Ketamine
- Where
- Germany
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Nursing Caries, Postoperative Pain
The Effect of Active Warming During General Anaesthesia on Postoperative Body Temperature, Shivering and Thermal Comfort
Adult patients who undergo surgery under general anaesthesia often experience inadvertent perioperative hypothermia. This common problem has serious consequences such as surgical site infection, coagulopathy, increased need for…
- Conditions
- Nursing Caries, Postoperative Pain, Postoperative Nausea and Vomiting
- Trial name
- NCT04907617
- Testing
- FAW, Warmed fluids, Combination
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Bozok University
Muscle Oxigenation, Strength
Changes in Oxygen Saturation in Two Exercise Modalities
The investigator will proceed to assess changes in oxygenation of muscle tissue, electromyographic activation and strength in healthy subjects.
- Trial name
- NCT02695017
- Testing
- Iso inertial, Conventional machine
- Where
- Spain
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Centro Universitario La Salle
Dehydration
Transdermal Optical Imaging (TOI) as a Non-invasive Measure to Detect Changes in Hydration Status in Healthy Adults and Athletes
The primary objective of this study is to analyze smart phone-based Transdermal Optical Imaging (TOI) features to develop a model that can discern hydration status, including: 1) at various timepoints throughout a 24-hour period…
- Trial name
- NCT06212518
- Testing
- GENPOP ad libitum fluid intake, GENPOP fluid restriction, ATHLETE ad libitum fluid intake
- Where
- 4 sites in United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Healthy, Overweight
The Effect of Blood Volume Changes on the Glucose Tolerance
In this study the investigators would like to elaborate on the mechanisms that lead to a higher insulin sensitivity after exercise training and a lower insulin sensitivity after bedrest.
- Trial name
- BV-GT (NCT02612597)
- Testing
- Bedrest, Exercise Training
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Carsten Lundby
Damage Muscle, Body Weight Changes
Chronic Study on Body Composition, Training, Performance, and Recovery
The chronic phase of the study will evaluate the effects of pre-exercise and post-exercise ingestion of a multi-ingredient supplement on adaptations to a 6-week exercise program consisting of both resistance training and high…
- Conditions
- Damage Muscle, Body Weight Changes, Performance Enhancing Product Use
- Trial name
- NCT04230824
- Testing
- Pre-workout plus and Protein recovery plus, 6-week resistance training program
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Pharmanex
Social Anxiety Disorder
Flushing in Social Anxiety Disorder on Cipralex
To add to our understanding of the relationship between blushing, symptom severity and potential mechanisms that underlie blushing in patients with SP, we propose comparing SP patients' vascular responses to topical m-N pre and…
- Trial name
- NCT00485888
- Testing
- Cipralex
- Where
- Canada
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- START Clinic for Mood and Anxiety Disorders
Lipids, Lipid Metabolism
RISSCI-1 Blood Cholesterol Response Study
Raised blood cholesterol (also referred to as blood LDL-cholesterol) is a major risk factor for developing heart disease. Dietary saturated fat is recognised as the main dietary component responsible for raising blood…
- Conditions
- Lipids, Lipid Metabolism, Healthy
- Trial name
- RISSCI-1 (NCT03270527)
- Testing
- High SFA diet (Diet 1), Low SFA diet (Diet 2)
- Where
- 2 sites in United Kingdom
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- University of Surrey
Physical Activity, Sedentary Lifestyle
Together we Move: A Multi-component Intervention to Increase Physical Activity for Ethnic Minority Older Adults
The benefits of physical activity (PA) for healthy aging are well known; however < 16% of U.S. older adults meet the federal recommendations for moderate to vigorous PA (MVPA).
- Trial name
- NCT03684070
- Testing
- Self-Monitoring, peer support and motivational prompts, Self-monitoring
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Boston College
Cognitive Change, Cognitive Impairment
The Everyday Function Intervention Trial
Loss of independence, cognitive decline, and difficulties in everyday function are areas of great concern for older adults and their families.
- Conditions
- Cognitive Change, Cognitive Impairment, Healthy Aging, Dementia
- Trial name
- EFIT (NCT04651582)
- Testing
- Cognitive Training, Cognitive Stimulating Activities
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Clemson University
HIV/AIDS, Gender
Transgender Youth and PrEP: PK, Safety, Uptake & Adherence - PK Study
To address the critical scientific gaps in PrEP safety for transgender youth and to plan for appropriate implementation of PrEP in transgender youth communities, the study will be conducted in 3 integrated phases.
- Conditions
- HIV/AIDS, Gender, Behavior and Behavior Mechanisms
- Trial name
- NCT03652623
- Testing
- TDF/FTC
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Hektoen Institute for Medical Research
Proliferative Diabetic Retinopathy
Intravitreal Bevacizumab vs Laser vs Combination of Bevacizumab and Modified Laser in PDR
In this randomized 3-armed clinical trial, 105 eyes with PDR will be included and divided randomly into 3 groups: IVB group (35 eyes) that receive 4 monthly IVB injections and then rescue IVB, PRP group (35 eyes) that undergo…
- Trial name
- NCT04800679
- Testing
- receive 4 monthly IVB injections and then rescue IVB, PRP group, IVB injections and a modified laser
- Where
- Iran
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Climate Change Awareness, Environmental Health Education
Effectiveness of Climate Change Awareness Education in Secondary School Students
This study aimed to evaluate the effect of a climate change awareness education program on knowledge, attitudes, and behaviors among secondary school students.
- Conditions
- Climate Change Awareness, Environmental Health Education, Health Behavior, Environmental Attitudes
- Trial name
- NCT07654686
- Testing
- Climate Change Awareness Education Program
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Postmortem Care
The Effect of Simulation-Based Postmortem Care on Nursing Students' Knowledge, Skills, and Self-Efficacy Levels
PURPOSE AND TYPE OF THE RESEARCH This study is designed as a randomized controlled experimental study to investigate the impact of simulation-based learning experiences in the teaching of postmortem care on the knowledge, skills…
- Trial name
- NCT07125456
- Testing
- Postmortem Care Teaching Simulation
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Bone Diseases, Metabolic, Acid-Base Imbalance
The Effect of Potassium Bicarbonate on Bone and Several Physiological Systems During Immobilisation
Mainly due to the absence of gravitational forces in weightlessness, astronauts suffer from an increased bone loss- negatively affecting health and vitality during a mission.
- Conditions
- Bone Diseases, Metabolic, Acid-Base Imbalance, Muscular Atrophy, Sprains and Strains
- Trial name
- NUC (NCT01509456)
- Testing
- Potassium Bicarbonate
- Where
- Germany
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- DLR German Aerospace Center
Quality of Life, Anal Fistula
Changes in Patients' Quality of Life With Differences in Seton Application
Investigators aim to investigate the changes in patients' quality of life with different type of seton application.
- Trial name
- NCT05348473
- Testing
- Alpha type, Beta type, Comfort type
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Ankara University
Cognitive Change
Sharing History Through Active Reminiscence and Photo-imagery (SHARP) Pilot Program
SHARP is a neighborhood-based and technology-supported approach to brain health for older Black adults that integrates walking and image-prompted social reminiscence to maintain or improve brain health.
- Trial name
- SHARP (NCT05906654)
- Testing
- Sharing History through Active Reminiscence and Photo-imagery (SHARP)
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
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