Clinical trials: Modification
Cognitive Change
Effects of Seaweed Extract on Mental Performance Following a High-carbohydrate Meal
The current study will explore the impact of seaweed extract on cognitive function following a high-carbohydrate meal at a number of time-points post-consumption.
- Trial name
- NCT03328923
- Testing
- 500mg brown seaweed powder
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Resistance Exercise, Physical Inactivity
Modified Breath Test to Determine Anabolic Sensitivity Across Physical Activity States
Developing tools to detect when our bodies are more resistant towards protein synthesis is valuable for identification of when someone may be at risk of losing body or muscle mass such as with aging or certain diseases.
- Conditions
- Resistance Exercise, Physical Inactivity, Amino Acids, Dietary Protein
- Trial name
- BTLP (NCT06209424)
- Testing
- Habitual Activity, Step-Reduction, Resistance Exercise
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Alzheimer's Disease
Early Markers of Cognitive Change and Alzheimer s Disease
Background: The Baltimore Longitudinal Study of Aging (BLSA) is a long-term study of human aging. To see how the brain changes with age, researchers will study BLSA participants who are at least 60 years old.
- Trial name
- NCT01867346
- Where
- United States
- Volunteers
- 2,850 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Diet Quality, Weight Loss
Alternative Dietary Approaches Online to Promote Tracking
Purpose: Compare the efficacy of two 3-month Internet-based interventions that use a simplified strategy for monitoring of dietary intake among young adult men and women with overweight or obesity.
- Trial name
- ADOPT (NCT05049005)
- Testing
- Simplified dietary tracking
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Climate Change, Adolescent
A Climate Change Education Program for 7th and 8th Grade Students in Istanbul Schools: Does It Improve Climate Knowledge and Health-Protective Behaviors?
Climate is the usual weather pattern of a place over a long time. Climate change means long-term shifts in climate, caused by natural processes and, above all, by human activity.
- Conditions
- Climate Change, Adolescent, Health Education, Health Behavior
- Trial name
- NCT07884279
- Testing
- a climate change education for students in secondary school.
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Berk Öngider
Noise-Induced Hearing Loss
Micronutrients to Prevent Noise-induced Hearing Loss
Noise-induced hearing loss (NIHL) is a significant clinical, social, and economic issue. Studies in animals have allowed us to identify mechanisms contributing to NIHL, including direct mechanical trauma, free radicals formed in…
- Trial name
- NCT00808470
- Testing
- beta-carotene, vitamins C and E, magnesium
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Life Style, Behavior
Welcome to WellnessRX: Steps Toward a Healthier Life!
Wellness Rx is a 6 class prescription for a healthier lifestyle developed for people in Lake County at all levels of health including those struggling with chronic disease.
- Conditions
- Life Style, Behavior, Food Habits, Stress
- Trial name
- WellnessRX (NCT03266666)
- Testing
- WellnessRX Lifestyle Change Classes, Thrive Market Grocery Credits (4x$25 each)
- Volunteers
- healthy volunteers welcome
- Sponsor
- ProofPilot
Peri-implant Mucositis, Soft Tissue Inflammation
Effect of Free Gingival Grafting on Peri-implant Health
The goal of this randomized clinical study is to investigate the impact of soft tissue phenotype modification following free gingival grafting (FGG) in addition to the non-surgical mechanical therapy of peri-implant mucositis…
- Trial name
- NCT06392256
- Testing
- Non surgical therapy, Free gingival Grafting
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Gazi University
Cannabis Dependence
Neural Indices Associated With Relapse in Cannabis Dependence
The aim of this fMRI study is to investigate neural indices of relapse in cannabis dependence. The development and maintenance of drug addictions have been associated with deficits in cognitive control, craving and impaired…
- Trial name
- NCT02801422
- Testing
- fMRI
- Where
- Germany
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Tooth Color
Effects of the Different Orthodontic Fixed Retainers on Enamel Colour Change
The aim of this study is to compare the tooth colour changes caused by retainers made of stainless steel wires and fiber reinforced in long term
- Trial name
- NCT04105829
- Testing
- Bond-a braid, EverStick-Ortho, Ribbond
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Gaziantep
Weight Loss
The Leeds Women's Wellbeing (LWW) Study
The purpose of this parallel design study is to assess the relative effects of two 12-week healthy eating dietary interventions: general healthy eating (Diet A) and general healthy eating combined with advice to increase fibre…
- Trial name
- LWW (NCT01539369)
- Testing
- Healthy eating diet (Diet A) or healthy eating diet combined with advice to increase fibre intake (Diet B) to at least 25g/day
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Diabetes Mellitus, Type 2
Technology Delivered Diabetes-Modified Behavioral Activation Treatment
The overarching goal of this proposal is to test the efficacy of a multi-component, high intensity intervention, technology delivered, diabetes-modified behavioral activation treatment (TECH DM-BAT) that incorporates: 1) diabetes…
- Trial name
- TECHDMBAT (NCT03593694)
- Testing
- TECH DM-BAT, TECH DMBAT Active Comparator, TECH DMBAT Other
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Fever
A Study of Ibuprofen 250 mg / Acetaminophen 500 mg Comparing The Antipyretic Effects in Healthy Male Volunteers
This is a single dose study that will evaluate the efficacy and safety of a Fixed Dose Combination Ibuprofen 250 mg/ Acetaminophen 500 mg tablet in healthy male patients with fever.
- Trial name
- NCT02761980
- Testing
- Ibuprofen 250 mg / Acetaminophen 500 mg, Ibuprofen 250 mg, Acetaminophen 500 mg
- Where
- United States
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Pfizer
Aging, Balance
Effects of Adapted Sports on Balance, Physical Function, and Cognitive Function in Older Adults
This randomized controlled study aims to investigate the effects of adapted sports exercises on balance, physical function, and cognitive function in older adults.
- Conditions
- Aging, Balance, Functional Mobility, Physical Function
- Trial name
- ASF (NCT07457996)
- Testing
- Adapted Sports Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Alanya Alaaddin Keykubat University
Irritable Bowel Syndrome
Altered Faecal Protease Activity in Irritable Bowel Syndrome Patients in China
Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder haracterised by abdominal pain or discomfort associated with altered bowel habits,while the mechanism is still not understood.Recent advances have…
- Trial name
- NCT01060527
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Xi'an Jiaotong University
ALS, Amyotrophic Lateral Sclerosis
Cortex Changes in Real/Imagined Movements in Amyotrophic Lateral Sclerosis (ALS)
The purpose of this study is to track areas of the brain, via functional magnetic resonance imaging (fMRI), that retain structural and functional integrity throughout the lifespan of people with amyotrophic lateral sclerosis…
- Trial name
- NCT00809224
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University of Michigan
SARS-CoV-2, Seasonal Influenza
A Study of Modified mRNA Vaccines in Healthy Adults
The main goal of this study is to evaluate the safety, reactogenicity, and immunogenicity of study vaccines.
- Conditions
- SARS-CoV-2, Seasonal Influenza, Respiratory Syncytial Virus, Cytomegalovirus
- Trial name
- NCT05397223
- Testing
- mRNA-1273, mRNA-1010, mRNA-1345
- Where
- 8 sites in United States
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- ModernaTX, Inc.
Aging
Age-related Changes in Posture Control and Cortex Activity Under a Dynamic Perturbation
With aging, the elderly decreased ability to control postural balance will be accompanied by increased risk of falling (Berg et al, 1992;. Tinetti et al, 1988).
- Trial name
- NCT02706496
- Where
- Taiwan
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Biomarkers of Cardiovascular Disease
Plasma and Urine TMAO Formation and Changes to Oxidized LDL After Ingestion of Different Amounts of Egg
Eggs contain an essential nutrient called choline and adequate levels of choline are required for good health. Studies in mice have demonstrated that high levels of choline may increase risk of heart disease through a process…
- Trial name
- NCT01906554
- Testing
- Egg Dose
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Anti-Mullerian Hormone Deficiency, Post Partum Hemorrhage
Anti-Mullerian Hormone (AMH) is a Marker for Ovarian Reserve. There Are Many Studies About AMH Changes in Ovarian Surgery, But Little is Known for Other Surgeries. We Seek to Investigate the Hormone Variations Before and After Uterine Artey Ligation for Postpartum Hemorrage (PPH)
Anti-Mullerian hormone (AMH) is a marker for ovarian reserve. There are many studies about AMH changes in ovarian surgery, but little is known for other surgeries.
- Trial name
- NCT03907605
- Testing
- anti- mullerian hormone
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
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