Clinical trials: Modification
Hypothermia, Postoperative Pain
Optimal Temperature Control in Body Contouring Procedures
The goal of this clinical trial is to compare different strategies for normothermia prevention in patients undergoing body contouring and other Aesthetic Plastic Surgery procedures.
- Conditions
- Hypothermia, Postoperative Pain, Postoperative Nausea, Postoperative Complications
- Trial name
- NCT06238739
- Testing
- Control - Standard Strategies for hypothermia prevention, Fluid warming before infusion and infiltration, Thermal convection blanket by water flow (Blanketrol)
- Where
- Colombia
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- Total Definer Research Group
Functional Dyspepsia
Mucosal Barrier Defects in Functional Dyspepsia by Confocal Laser Endomicroscopy
There has been recent interest into the potential role of mucosal barrier defects in the pathophysiology of functional gastrointestinal disorders (FGIDs).
- Trial name
- NCT01006642
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Shandong University
COVID19, Herbal Medicine
Changing Susceptible Body Constitution for COVID-19 Prevention by Chinese Medicine in Hong Kong Residents
Chinese medicine has been used for thousands of years in the treatment of epidemic diseases. Through the long-term struggle with the epidemic, Investigators have accumulated and explored a lot of prevention and control…
- Trial name
- NCT04668222
- Testing
- Yu-Ping-Feng formula, Xiang-Sha-Liu-Jun formula, Liu-Wei-Di-Huang formula
- Where
- Hong Kong
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Obesity, Overweight
The Effect of Repeated Lifestyle Intervention on Weight Loss Maintenance
In Denmark and the western world, there is an increasing prevalence of obesity probably due to a combination of inadequate daily physical activity and a high energy intake.
- Trial name
- NCT02040753
- Testing
- Intensive Lifestyle Intervention
- Where
- Denmark
- Volunteers
- 2,120 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Type 1 Diabetes Mellitus Maturity Onset
Altered Faecal Microbiome and Metabolome in CT1D, AT1D and T2D
To elucidate the characteristics of global gut microbiota and fecal/serum metabolites in patients with childhood-onset type 1 diabetes, adult-onset type 1 diabetes or type 2 diabetes.
- Trial name
- NCT05252728
- Where
- China
- Volunteers
- 372 people, healthy volunteers welcome
- Sponsor
- Second Xiangya Hospital of Central South University
Shift Work
Measuring the Cardio-metabolic Response to Diet Quality Modification During Night Work.
The aim of this pilot study is to investigate the acute impact of diet quality modification during night work on 24-hr glucose variability (GV) and heart rate variability (HRV) in healthy free-living employees.
- Trial name
- NCT04182867
- Testing
- Dietary intervention
- Where
- United Kingdom
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- King's College London
Postural Balance, Foot
Changes in Stabilometry After Neural Mobilisation in Foot
Investigation will consist of measuring before and after applying nerve mobilization exercise. Measurements will be made on the same day without the need to go at another time.
- Conditions
- Postural Balance, Foot, Therapy, Rehabilitation
- Trial name
- NCT05190900
- Testing
- neural mobilization
- Where
- Spain
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Mayuben Private Clinic
Heat Stress, Physiological Stress
Impact of Indoor Overheating on Physiological Strain in Children
Communities worldwide are experiencing increasing heat extremes that challenge the limits of human thermoregulation, particularly among vulnerable populations such as children.
- Conditions
- Heat Stress, Physiological Stress, Cognitive Change
- Trial name
- NCT07261202
- Testing
- Simulated exposure to indoor overheating
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Cardiovascular Diseases, Metabolic Disorders
Chinese Migrant Population Health Cohort
The Chinese Migrant Population Health Cohort is a prospective, multi-center study jointly initiated by Professor Yong Ji, President of Harbin Medical University, and Academician Guoqiang Chen, President of Hainan Medical…
- Conditions
- Cardiovascular Diseases, Metabolic Disorders, Ageing and Geriatric Health, Climate Adaptation
- Trial name
- NCT07124949
- Testing
- No intervention
- Where
- China
- Volunteers
- 26,000 people, healthy volunteers welcome
- Sponsor
- Jinwei Tian
Olfactory Impairment
The Efficacy of Modified Olfactory Training for Patients With Olfactory Dysfunction
The goal of this clinical trial is to validate the effectiveness of the modified olfactory training device, the main questions it aims to answer are: Is it possible that the device can treat olfactory disorders in adults?…
- Trial name
- NCT06353139
- Testing
- Modified olfactory training device
- Where
- China
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Diabetic Retinopathy, Neurodegeneration
Glycemic Control and Retinal Microvascular Changes
The goal of this prospective, observational study is to compare in the association of glycemic control and retinal microvascular changes in patients with type 2 diabetes mellitus (T2DM) without diabetic retinopathy (DR).
- Conditions
- Diabetic Retinopathy, Neurodegeneration, Blood Sugar; High
- Trial name
- NCT06150495
- Where
- South Korea
- Volunteers
- 259 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Chemotherapy-induced Peripheral Neuropathy, Peripheral Neuropathy
Visualize Nociceptor Changes in Neuropathic Human
The purpose of this experiment is to establish a solid medical foundation for the successful development of non-invasive harmonic generation (HGM) microscopic slicing methods.
- Trial name
- NCT03112057
- Testing
- harmonic generation (HGM) microscopic methods.
- Where
- Taiwan
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Primary Glaucoma
Changes of Trace Elements in Aqueous Humor, Blood and Tears and Analysis of Related Factors
Trace elements are one of the indispensable substances in human body and play an important physiological role. Zinc is a trace element second only to iron in organisms, which is widely distributed in various systems and organs…
- Trial name
- NCT04515030
- Where
- China
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Obesity, Obesity, Morbid
Effects of Differences in Body Composition on Retina and Choroid
The goal of this observational study is to examine the effects of body composition differences on retinal and choroidal structures.
- Conditions
- Obesity, Obesity, Morbid, Body Composition
- Trial name
- NCT06888765
- Testing
- Optical Coherence Tomography (OCT) and Body Composition Analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 261 people, healthy volunteers welcome
- Sponsor
- Bayram Meydan
Cognitive Change
Immediate and Residual Effects of Functional Chewing Gum on Concentration
Previous research suggests that chewing gum may influence several functions including attention and alertness. Gum can also be used as a vehicle for delivering ingredients that have the ability to modulate attention and mood.
- Trial name
- NCT05544500
- Testing
- Functional Gum, Basic Chewing Gum
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Obesity
"Efficacy in Adolescents of Continued Behavior Modification Following a Six Month Sibutramine-based Weight Management Intervention"
There are few studies that look at sustained weight loss in the adolescent population. This study uses a multidisciplinary approach along with pharmacotherapy (use of Meridia)to motivate and establish behavior changes in…
- Trial name
- AOS (NCT01023139)
- Testing
- Sibutramine
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Brooke Army Medical Center
Choroid Disease, Hypertension Ocular
Study of Changes in Retrofoveolar Choroidal Thickness During Aerobic Exercise
Study the change of retrofoveolar choroidal thickness measured by optical coherence tomography during aerobic exercise inducing an increase in systolic blood pressure in healthy subjects.Ten healthy participants will perform an…
- Trial name
- MOPAS (NCT03532867)
- Testing
- Examination of pressures before stopping the exercise, Examination of pressure during the exercise, Examination of pressures after stopping the exercise
- Where
- France
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Smallpox
ACAM 3000 MVA at Harvard Medical School
The purpose of this study is to assess the safety of an experimental smallpox vaccine (MVA: Modified Vaccinia Ankara) and to compare the body's immune (system that fights disease) response to this vaccine.
- Trial name
- NCT00133575
- Testing
- MVA Smallpox Vaccine, Live vaccinia virus vaccine
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
COVID-19 Infection
Changes in Seroprevalence and Wellness Over Time in Healthcare Workers (CONSERVE-HCW)
The Investigators propose a multi-center, observational, longitudinal, cohort study of the serology and wellness of HCWs over a year of the COVID-19 pandemic.
- Trial name
- CONSERVE-HCW (NCT04595175)
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Brian Tiffany, MD
Ventral Hernia, Abdominal Wall Defect
Intraoperative Biomechanics in Complex Abdominal Wall Reconstruction
Background: A detailed study of the biomechanical changes before and after abdominal wall reconstruction (AWR) has not been performed.
- Trial name
- NCT03296475
- Testing
- Abdominal Wall Closure Force (N).
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University College, London
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