Clinical trials: Modification
Smoking Cessation
Patient Experience Recommender System for Persuasive Communication Tailoring
The purpose of this study is to maximize patient perspective and effectively support lifestyle choices, investigators will develop the "Patient Experience Recommender System for Persuasive Communication Tailoring." PERSPeCT is a…
- Trial name
- PERSPECT (NCT02200432)
- Testing
- PERSPeCT Recommender System
- Where
- United States
- Volunteers
- 972 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Obesity, Weight Loss
Evaluation of Alternative Exercise Treatments on Weight Loss in Overweight Women.
The purpose is to examine the additional effect of either yoga or resistance exercise on weight loss weight combined with a standard behavioral weight loss intervention.
- Trial name
- NCT00177632
- Testing
- behavioral weight loss
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Intrabony Periodontal Defect
Evaluation of Modified Minimally Invasive Surgical Technique and Platelet Rich Fibrin With or Without Vitamin Pool A and C for Management of Periodontal Intrabony Defects
This study aims to assess clinical and radiographic outcomes after the use of vitamins A and C with PRF versus PRF alone in the treatment of periodontal intrabony defect.
- Trial name
- NCT05499598
- Testing
- Experimental: Modified minimally invasive surgical technique with PRF and vitamins A and C, Modified minimally invasive surgical technique with PRF
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Cairo University
Overweight
TeleLifestyleCoaching for Weight Loss
Lifestyle changes often fail due to loss of motivation. Telemedicine and personal coaching have the potential to support lifestyle change and weight loss.
- Trial name
- FitMeFit (NCT01868763)
- Testing
- telemedical devices (weighing machine and step counter), care calls once per week for 12 weeks
- Where
- Germany
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- West German Center of Diabetes and Health
Active Rheumatoid Arthritis
A Phase IIIb Study of BMS-188667 in Subjects With Active Rheumatoid Arthritis and Inadequate Response to Methotrexate
The only trial in participants who are methotrexate-inadequate responders and have active Rheumatoid Arthritis, in which gadolinium-enhanced Magnetic Resonance Imaging; Bone Mineral Density; and biochemical markers of bone…
- Trial name
- NCT00420199
- Testing
- Abatacept
- Where
- 10 sites in Belgium, Germany and 4 more
- Volunteers
- 50 people
- Sponsor
- Bristol-Myers Squibb
Weight Gain
Post Disaster Nutrition Intervention for Under-two-year-old Children in Lombok Indonesia
In 2018, multiple earthquake with magnitude range from 6 to 7 hit Lombok Island, West Nusa Tenggara Province, Indonesia. Following the situational analysis and baseline study in December 2018 (4 months after the first…
- Trial name
- NIELombok (NCT03895398)
- Testing
- nutrition and psychosocial intervention with community participatory
- Where
- Indonesia
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- SEAMEO Regional Centre for Food and Nutrition
Adolescent Obesity, Diet
Chrononutrition and Adolescent Weight Control
Comprehensive lifestyle interventions are recommended for the treatment of adolescent obesity; however, evidence suggests that they are not as effective in teens as they are in children and adults.
- Conditions
- Adolescent Obesity, Diet, Weight Loss, Sleep
- Trial name
- NCT04256863
- Testing
- Breakfast / Lunch, Dinner (DIN)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
High and Increasing Contribution of Energy From Beverages in the Diet May Enhance Positive Energy Balance and Weight Gain
Effects of Food Form and Fitness on Appetite and Digestion.
Energy-yielding fluids induce weaker appetitive and compensatory dietary responses than energy-matched semi-solids or solids. This is problematic because the high and increasing contribution of energy from beverages in the diet…
- Trial name
- NCT01070199
- Testing
- liquid to liquid, liquid to solid, solid to liquid
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Purdue University
Venous Insufficiency
SocknLeg - a User Friendly Medical Compression Study of a Modified Application of a Medical Device
The study intends to investigate a novel compression system termed Socknleg composed of an understocking covering the foot with three added stockings extending from the ankle to the knee without covering the foot.
- Trial name
- Socknleg (NCT02621632)
- Testing
- (Socknleg)To done of a novel compression system
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Spinal Anesthesia, Hemodynamic Changes
Effect of Patient Position on Bupivacaine Dose Requirement and Hemodynamic Stability in Spinal Anesthesia
This study compares different combinations of local anesthetic doses and patient positions during spinal anesthesia for urogenital surgery.
- Conditions
- Spinal Anesthesia, Hemodynamic Changes, Patient Positions, Bupivacaine
- Trial name
- NCT07376798
- Testing
- Bupivacaine %0.5 (hyperbaric)
- Volunteers
- 100 people
- Sponsor
- University of Health Sciences Balikesir Hospital Eduation and Research
Appetite Suppression, Weight Loss
Effects of a Dietary Fibre Supplementation of a Low Calorie Diet on Appetite and Body Weight
This 18 week, randomized, double blind, placebo controlled trial will examine the effects of thick dietary fibre (PGX) supplementation of a low calorie diet (LCD) on appetite, weight loss, body composition, and compliance in…
- Trial name
- NCT01109199
- Testing
- PolyGlycopleX (PGX), Rice flour
- Where
- 2 sites in Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Canadian Center for Functional Medicine
Obesity, Overweight
PACE-CALL: A Weight Control Intervention for Survivors of Childhood Leukemia
The purpose of this National Cancer Institute (NCI) funded study is to develop and test the acceptability and usability of a web \& text message based weight loss intervention for childhood acute lymphoblastic leukemia (ALL)…
- Conditions
- Obesity, Overweight, Weight Loss, Weight Maintenance
- Trial name
- PACE-CALL (NCT01171599)
- Testing
- Fit4Life
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of California, San Diego
Glioblastoma
Multimodal Imaging Analysis During Treatment With Bevacizumab in Patients With Recurrent Glioblastoma
The purpose of this study is to estimate the capacity of the multimodal imaging parameters measured at 15 days and 2 months of initiation of treatment with bevacizumab, to measure changes in clinical status (sensitivity to…
- Trial name
- IMAGLIO (NCT02841332)
- Testing
- F-MISO, Cerebral magnetic resonance imagery, Bevacizumab
- Where
- France
- Volunteers
- 6 people
- Sponsor
- University Hospital, Toulouse
Smoking Cessation, Weight Loss
Comparing Two Treatments That Both Target Smoking Cessation and Weight Loss at the Same Time.
The study has two phases. In Phase 1, the investigators will revise and pilot the distress tolerance (DT) protocol that was originally developed and piloted in a previous study (2P20 GM103430, Spas, PI).
- Trial name
- BREATH (NCT04130698)
- Testing
- Distress Tolerance, transdermal nicotine patch, Active Health Control
- Where
- United States
- Sponsor
- Rhode Island College
Hepatocellular Carcinoma
A Study of Changes in Hepatic Function During Radiation Therapy Using Hepatobiliary Single Photon Emission Tomography (SPECT)
Radiation-induced liver disease (RILD) is a syndrome characterized by the development of anicteric ascites approximately 2 weeks to 4 months after hepatic irradiation.
- Trial name
- NCT01519232
- Testing
- Liver Irradiation
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Michigan Rogel Cancer Center
Parkinson's Disease
Non-invasive Measurement of Brain Oxygen Levels in People With Subthalamic Deep Brain Stimulators
The purpose of this study is to determine if deep brain stimulation can change brain oxygen levels in people with Parkinson's Disease.
- Trial name
- NCT02278406
- Testing
- Deep brain stimulator
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Beth Israel Deaconess Medical Center
Retrospective Study
Predicting Outcomes of Breast-Conserving Surgery in Breast Cancer Patients Using the Modified 5-Item Frailty Index
Background: Breast cancer is the most common malignancy among women worldwide, with breast-conserving surgery (BCS) being a key treatment.
- Trial name
- NCT06770647
- Where
- Germany
- Volunteers
- 96,586 people
- Sponsor
- Technical University of Munich
HIV Infections
Analysis of Changes in Adipose Tissue of Patients With Lipoatrophy HIV Infection Treated With Nucleoside Thymidine, After Switching to Monotherapy With Lopinavir / Ritonavir
The objective is to analyse the changes in the adipose tissue hystological features and the adipogenesis gene expression and related to inflammation after 48 and 96 weeks after the change from AZT+3TC+ABC (Trizivir®) to a…
- Trial name
- BIOKAL (NCT01031849)
- Testing
- Kaletra
- Where
- 2 sites in Spain
- Volunteers
- 7 people
- Sponsor
- Ines Perez
Rewarming by Shivering Heat Production Only, Rewarming by Arm and Leg Immersion in Warm Water
Hypothermia Rewarming With Distal Limb Warming
The study will compare the rewarming effectiveness of heat donation through the distal arms and legs during rewarming of mildly hypothermic subjects.
- Conditions
- Rewarming by Shivering Heat Production Only, Rewarming by Arm and Leg Immersion in Warm Water, Rewarming by Arm and Leg Exposure to Fluidotherapy
- Trial name
- NCT01827449
- Testing
- Fluidotherapy warming device
- Where
- Canada
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Lateral Ankle Instability
Modified Brostrӧm Procedure With and Without Possible Arthroscopy for Lateral Ankle Instability
This study is to show that the investigators believe the Modified Brostrӧm Procedure (MBP) can be completed without a routine ankle arthroscopy.
- Trial name
- NCT02470338
- Testing
- MBP plus arthroscopy (Group A), MBP alone (Group B)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Edna Rath
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.