Clinical trials: Modification
Erb's Palsy
Effects of Modified Constraint-induced Movement Therapy With and Without Electrical Stimulation in Erb's Palsy
ERB's palsy is an injury of upper section of the brachial plexus (C5-6) leading to an internally rotated and adducted shoulder and a pronated forearm.
- Trial name
- NCT06303427
- Testing
- Modified constraint-induced movement therapy, Electrical stimulation
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- Riphah International University
Cognitive Change
Understanding Individual Differences in Working Memory Training and Transfer in Older Adults
The present study investigates how individual differences in cognitive processing contribute to the efficacy of working memory training programs in an older adult population.
- Trial name
- NCT05396586
- Testing
- N-back, Span, Multisensory
- Where
- 2 sites in United States
- Volunteers
- 313 people, healthy volunteers welcome
- Sponsor
- Northeastern University
Aldosteronism
Postoperative Cardiovascular Index Change of Primary Aldosteronism
Primary aldosteronism (PA), characterized by an inappropriate production of aldosterone, is far more common than is usually perceived.
- Trial name
- TAIPAI (NCT00746070)
- Testing
- with the clinical treatment ( ex adrenalectomy or spironolactone
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Breast Cancer
PEAK PlasmaBlade™ 4.0 Versus Traditional Electrosurgery in Lumpectomy
The purpose of this clinical study is to quantify the difference in thermal injury depth at the surgical margin in breast lumpectomy specimens excised with the PlasmaBlade; to subjectively assess histopathologic sample quality…
- Trial name
- PRECISE (NCT00960154)
- Testing
- PEAK PlasmaBlade, Traditional Electrosurgery with scalpel
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Medtronic Surgical Technologies
Overtraining Syndrome
Changes in the Hormonal and Inflammatory Profile of Young Sprint- and Endurance-trained Athletes.
One essential element of athlete training is conditioning camps, where athletes undergo a rigorous and targeted training schedule to prepare for upcoming sporting events.
- Trial name
- CHIPYA (NCT06150105)
- Testing
- Exercise training
- Where
- Poland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Obesity
Banded Sleeve Gastrectomy Versus Banded Ring Gastric Bypass in Morbidly Obese Patients
Obesity is a multifactorial disease that affects millions of people worldwide. It is the main independent risk factor for developing type 2 diabetes mellitus (T2DM).
- Trial name
- NCT00873405
- Testing
- Silastic® ring sleeve gastrectomy, Silastic® ring gastric bypass
- Where
- Brazil
- Volunteers
- 65 people
- Sponsor
- Federal University of Espirito Santo
Gait, Flexibility
Age-Related Gait Changes and Hip Flexibility
Based on their preliminary quantitative gait findings suggesting that limited passive hip extension range is a key functionally limiting impairment affecting gait, the investigators propose a supervised, specific stretching…
- Trial name
- NCT00924261
- Testing
- Hip Stretch, Shoulder Stretch
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Autism Spectrum Disorder, Autism
Autism Spectrum Disorder (ASD) Neurodevelopmental Disorder With Issues Social Behavior, Communication Issues, GI Dysfunction. Study is Multimodal Interventions Targeting These Pathways With cSVF, Stored MSCs, FMT and Diet Modification. Role of Autoimmunity, Gut-brain Issues, & Issues Examined.
Autism spectrum disorder (ASD) is a neurodevelopmental condition with core deficits in social communication and behavior, often accompanied by gastrointestinal (GI) and metabolic dysfunction.
- Conditions
- Autism Spectrum Disorder, Autism, Autism Spectral Disorder
- Trial name
- GARM-Autism (NCT07546942)
- Testing
- Autologous MSC isolation, concentration, and cryopreservation of adult mesenchymal stem cells, Fecal Biomicrome Transplantation (FMT), Ketogenic RESET Diet Protocol
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Black Tie Medical, Inc.
Temperature Change
Clinical Trials for Comparison of Two Kinds of Moxibustion
The purpose of this study is to evaluate efficacy of Shingigu and Charcoal moxibustion scientifically and objectively.
- Trial name
- NCT01366456
- Testing
- Moxibustion
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Semyung University
Malnourished Children With Watery Diarrhoea
Modified ORS Solution for Severely Malnourished Children
Diarrhoea and malnutrition are the common childhood illnesses responsible for higher deaths in developing counties. Physiologically, malnourished children excrete lower amounts of salts and water in diarrhoeal stools, and they…
- Trial name
- NCT01821586
- Testing
- Modified ORS-1, Modified ORS-2 (ReSoMal), Modified ORS-3 (Benefibre)
- Where
- Bangladesh
- Volunteers
- 189 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Parkinson's Disease
Managing Changes in Life After Deep Brain Stimulation for Parkinson's Disease
Parkinson's disease is a chronic progressive neurological disorder. Symptoms are tremor, slowness in movement, rigidity and postural instability.
- Trial name
- NCT01681641
- Testing
- A psycho-social intervention
- Where
- 3 sites in Denmark
- Volunteers
- 32 people
- Sponsor
- University of Aarhus
Osteoarthritis, Knee, Menopause
Efficacy Study of Shortwave Diathermy for the Treatment of Patients With Knee Osteoarthritis
The purpose of this study is to determine whether shortwave diathermy is effective in reducing knee pain and increasing function of the patients with knee osteoarthritis.
- Trial name
- NCT00199914
- Testing
- Shortwave diathermy
- Where
- Thailand
- Volunteers
- 113 people
- Sponsor
- Mahidol University
Dental Caries, Dental Occlusion
Occlusal Impact of Hall Crowns in Primary Molars
Hall Technique is a non-invasive restorative approach for managing carious primary molars, increasingly used in pediatric dentistry due to its simplicity and patient tolerance.
- Conditions
- Dental Caries, Dental Occlusion, Pediatric Dentistry
- Trial name
- NCT07134114
- Testing
- Hall Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Childhood Obesity, Feeding Behavior
Evaluation of a Primary Care Weight Management Program in Children Aged 2 to 5 Years
Primary care offers a promising setting for promoting parenting practices that shape healthy eating and physical activity behaviors of young children.
- Conditions
- Childhood Obesity, Feeding Behavior, Physical Activity
- Trial name
- NCT03487614
- Testing
- Behavior-based parental intervention
- Volunteers
- 184 people
- Sponsor
- Corewell Health West
Diabetes Mellitus, Type 2
The FreeStyle Libre Enabled Reduction of A1c Through Effective Eating and Exercise Study
This two-year multisite, real-world, before-after prospective six-month pilot study utilizing a single-group cohort design (n=184) which will first occur in London, Ontario (n=92) through the St.
- Trial name
- LIBERATE (NCT05261906)
- Testing
- LIBERATE
- Where
- Canada
- Volunteers
- 184 people
- Sponsor
- Western University, Canada
Obesity, Overweight
Bariatric Outcomes Longitudinal Database (BOLD)
The primary purpose of the Bariatric Outcomes Longitudinal Database (BOLD) study is to assess the mid- and long-term outcomes of bariatric surgeries and to analyze the relationship between these outcomes and 1) patient…
- Conditions
- Obesity, Overweight, Diabetes
- Trial name
- BOLD (NCT01002352)
- Where
- United States
- Volunteers
- 600,000 people
- Sponsor
- Surgical Review Corporation
Melanoma
Neoadjuvant Dabrafenib + Trametinib for AJCC Stage IIIB-C BRAF V600 Mutation Positive Melanoma
This is an open label, single centre, phase II study of neoadjuvant drug treatment with dabrafenib + trametinib in patients with resectable American Joint Committee on Cancer (AJCC) Stage IIIB-C BRAF V600 mutation positive…
- Trial name
- Neo Combi (NCT01972347)
- Testing
- Dabrafenib, Trametinib
- Where
- Australia
- Volunteers
- 35 people
- Sponsor
- Melanoma Institute Australia
Sedation
Pharmacokinetics and Pharmacodynamics of Oral Transmucosal Dexmedetomidine.
Oral trans-mucosal administration is relatively easy and convenient, it also reduces first pass metabolism and has been used successfully for fentanyl, ketamine, and midazolam premedication.
- Trial name
- OTM/DEX/PK (NCT03120247)
- Testing
- OTM Dexmedetomidine 1µg/ kg., OTM Dexmedetomidine 0.75µg/ kg., OTM Dexmedetomidine 0.5µg/ kg.
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Assiut University
Antiphospholipid Syndrome, COVID-19 Infection
Prospective Observational Study to Evaluate a Possible Change in APS Antibody Profiles After COVID-19 Infection or Vaccination
Prospective observational study to evaluate a possible change in APS antibody profiles after COVID-19 infection or vaccination
- Conditions
- Antiphospholipid Syndrome, COVID-19 Infection, COVID-19 Vaccination
- Trial name
- APSantiCo (NCT05313048)
- Where
- Germany
- Volunteers
- 82 people
- Sponsor
- Cardioangiologisches Centrum Bethanien
Pit and Fissure Sealants
Clinical Evaluation of Pit and Fissure Sealants
Pit and fissure sealants are considered an effective preventive approach in protecting teeth from caries, particularly by transforming deep, plaque-retentive occlusal surfaces into smooth, easily cleanable areas.
- Trial name
- NCT06987955
- Testing
- Biocoat Pit and fissure sealant, Fissurit FX Pit and fissure sealant
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Canan Bayraktar Nahir
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