Clinical trials: Modification
Weight Gain
Oxytocin and Eating
In this protocol, the investigators propose a randomised controlled trial to explore the effects of intra-nasal oxytocin administration on appetite regulation.
- Trial name
- NCT03225456
- Testing
- Syntocinon
- Where
- Singapore
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yale-NUS College
Regional Anesthesia Morbidity
M-TAPA vs Intraperitoneal Bupivacain vs Intraperitoneal Bupivacain +Dexmedetomidin
Laparoscopic cholecystectomy is a common abdominal surgery in Western countries, favored for its minimal invasiveness, leading to less pain, smaller scars, and quicker recovery.
- Trial name
- NCT06482229
- Testing
- application for postoperative analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Sivas State Hospital
Obesity & Overweight, Prediabetes
Precision Nutrition for Obesity and Prediabetes Prevention in Under-supported Communities
This randomized controlled trial will evaluate the effectiveness of a culturally sensitive precision nutrition intervention for improving obesity- and diabetes-related outcomes among African American and Hispanic/Latino adults…
- Trial name
- PNOD (NCT07850531)
- Testing
- Precision Nutrition Intervention, Standard Nutrition Counseling
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Prairie View A&M University
Discomfort Symptoms, Changed Lung Function
Dose Response Relations for Health Effects Caused by Office Dust
The study is focused at the dose response relation for office dust and such office dust spiked with components from fungi known from damp buildings.
- Trial name
- NCT00143637
- Testing
- Office dust, clean air
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Osteoporosis
Changes in Biochemical Markers of Bone Turnover (Serum CTX and PlNP) After Initiation of a "Drug Holiday" From Bisphosphonates
Bisphosphonates (BP) are widely used in the prevention and treatment of osteoporosis in postmenopausal women and older men. Recently, there has been concern about the risk of adverse events after several years of using these…
- Trial name
- NCT02575157
- Testing
- No intervention
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- National Bone Health Alliance
Fongal Infection
Fungal Infection on a Joint Prosthesis
It is generally accepted that the fungal infection on a joint prosthesis is to be treated in two surgical time: implant removal and prosthetic reconstruction.
- Trial name
- NCT02467712
- Volunteers
- 4 people
- Sponsor
- University Hospital, Strasbourg, France
Weight Loss
MyBehavior: Persuasion by Adapting to User Behavior and User Preference
MyBehavior is a mobile application with a suggestion engine that learns a user's physical activity and dietary behavior, and provides finely-tuned personalized suggestions.
- Trial name
- NCT02359981
- Testing
- MyBehavior, Generic suggestions, Smartphone
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Cornell University
Allogeneic Hematopoietic Stem Cell Transplantation, Allogeneic Stem Cell Transplantation
Risk-ADAPTed Conditioning Regimen for Allogeneic Hematopoietic Stem Cell Transplantation
This is a prospective, single-arm, phase II study. Patients will be treated with an allogeneic stem cell transplantation (AHSCT) using fludarabine, melphalan and total body irradiation (TBI) conditioning with different melphalan…
- Conditions
- Allogeneic Hematopoietic Stem Cell Transplantation, Allogeneic Stem Cell Transplantation, Hematologic Malignancies
- Trial name
- ADAPT (NCT06028828)
- Testing
- Fludarabine, Melphalan, Total Body Irradiation
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of California, Irvine
Taste Perception, Fixed Orthodontic Appliances
Taste Changes With Fixed Orthodontic Appliances
The aim of this research: 1. To analyze the possible influence of fixed orthodontic appliances on taste perception among patients undergoing conventional orthodontic treatment. 2.
- Trial name
- NCT06093256
- Testing
- Fixed orthodontic appliances
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Riyadh Elm University
Colorectal Cancer
The Benefits of Deep Neuromuscular Block and Sugammadex in Laparoscopic Colorectal Surgery
Pneumoperitoneum, the use of carbon dioxide, presents some disadvantages, including a risk of hypercarbia and respiratory acidosis during surgery in the respiratory system, and of an increased mean arterial pressure and systemic…
- Trial name
- NCT02266056
- Testing
- Deep neuromuscular block using rocuronium and reversal with suggamadex, Moderate neuromuscular block using rocuronium and reversal with suggamadex
- Where
- South Korea
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Weight Loss
Safety and Efficacy of IQP- AK-102 in Reducing Body Weight
The individual ingredients in IQP-AK-102 have been widely used. Backed by data from several studies demonstrating their efficacy, we are conducting this study to look into the efficacy and safety of this novel combination of…
- Trial name
- NCT01905956
- Testing
- IQP-AK-102
- Where
- Germany
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- InQpharm Group
Child, Only, Narration
Effects of a Group EMDR Intervention on Narrative Complexity and Specificity of Autobiographical Memories: the Hug the Child Study (HTC)
Background and study aims: The Eye Movement Desensitization and Reprocessing Group Protocol with Children (EMDR-GP/C) was first developed by Korkmazlar following the Marmara earthquake in Turkey in 1999 and can be adapted for…
- Conditions
- Child, Only, Narration, Memory Dysfunction, Distress, Emotional
- Trial name
- HTC (NCT05319002)
- Testing
- Group EMDR
- Where
- Italy
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Pisa
Weight Loss, Hormone Disturbance
Effects of Weight Loss on Nutritional Mediated Hormone Secretion
Investigative trial with aim of 1. the description of the hormonal and metabolic response to meals containing different compositions of macronutrients 2.
- Conditions
- Weight Loss, Hormone Disturbance, Weight Gain
- Trial name
- RepDiet (NCT02649907)
- Testing
- nutritional stimulation via different testmeals, Nutritional counseling, formula diet
- Where
- Germany
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Brain Metastases, Brain Metastases, Adult
Developing a New MRI Technique to Understand Changes in Brain Tumors After Treatment
The purpose of this study is to develop and test a new magnetic resonance imaging (MRI) technique to see if it can be used to tell the difference between tumor growth from worsening of cancer and growth from the effects of…
- Conditions
- Brain Metastases, Brain Metastases, Adult, Metastatic Brain Tumor, Metastatic Brain Cancer
- Trial name
- NCT05559853
- Testing
- CEST-MRF
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
HIV Infections
The CogNaive Study: Assessing Changes in Neurocognitive Function in Treatment Naïve HIV-1 Positive Subjects
The purpose of this study is to investigate the possibility of an association between changes in neurocognitive function, as measured by a computerised test battery, and the use of two different highly active antiretroviral…
- Trial name
- NCT00540137
- Testing
- nevirapine, atazanavir/ritonavir
- Where
- 2 sites in United Kingdom
- Volunteers
- 21 people
- Sponsor
- Imperial College London
Primary Angle Closure Glaucoma
Optical Coherence Tomography Quantitative Analysis of Changes in Anterior Chamber After Laser Peripheral Lridotomy
The purpose of this study is to analysis changes in anterior segment morphology after laser peripheral lrldotomy measured by optical coherence tomography, and to evaluate treatment effectiveness
- Trial name
- NCT02279472
- Testing
- Laserex Tango Nd:YAG, Ellex-SuperQ Medical, Australia
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Second Xiangya Hospital of Central South University
Fatty Liver
Insulin Resistance in Non-alcoholic Fatty Liver Disease
The study is designed to investigate the relationship between insulin resistance and non-alcoholic fatty liver disease (NAFLD) and to investigate potential mechanisms underlying insulin resistance in NAFLD by determining…
- Trial name
- NCT01289639
- Testing
- fenofibrate, pioglitazone
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Erector Spinae Plane Block, Modified Radical Mastectomy
Perioperative Analgesic Effect of Two Different Volumes of Local Anesthetic Solution in Erector Spinae Plane Block in Patients Undergoing Modified Radical Mastectomy
Comparing the perioperative analgesic effect of two different volumes of local anesthetic solution in erector spinae plane block in patients undergoing modified radical mastectomy. A randomized comparative study.
- Trial name
- NCT06498739
- Testing
- Erector spinae plane block(15 ml bupivacaine 0.5%), Erector spinae plane block (15 ml bupivacaine 0.5% and 15ml normal saline)
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Cairo University
Self Harm, Substance-Related Disorders
CMAP Plus Intervention for Self-harm in Individuals With Substance Use Disorder in Pakistan
Objectives: To determine the feasibility and acceptability of the culturally adapted CMAP Plus CBT based Motivational Interviewing (MICBT) called CMAP Plus for self-harm in individuals with substance use disorder (SUD) in a…
- Trial name
- CMAP Plus (NCT05476601)
- Testing
- CMAP Plus
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Pakistan Institute of Living and Learning
Female Infertility, Polycystic Ovary Syndrome
Evaluation of Clinical Outcomes and Costs of a Lifestyle Intervention in Obese Infertile Women
BACKGROUND: Obesity increases the risk of polycystic ovary syndrome (PCOS), characterized by anovulatory cycles, but it is also associated with reduced fertility even in ovulatory women.
- Conditions
- Female Infertility, Polycystic Ovary Syndrome, Obesity
- Trial name
- OF (NCT01483612)
- Testing
- Interdisciplinary lifestyle intervention
- Where
- Canada
- Volunteers
- 130 people
- Sponsor
- Université de Sherbrooke
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