Clinical trials: Modification
Weight Gain, Disorder of Bone Density and Structure, Unspecified
Drug Exposure and Depot Medroxyprogesterone Acetate (DMPA) in Adolescent Subjects
The investigators are doing this study to look at how different doses of the Depot medroxyprogesterone acetate (DMPA) shot effect weight gain and bone mineral density in teens.
- Conditions
- Weight Gain, Disorder of Bone Density and Structure, Unspecified, Uterine Bleeding
- Trial name
- NCT01461824
- Testing
- Depot medroxyprogesterone acetate (DMPA)
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Nationwide Children's Hospital
Depression, Bipolar
Functional and Neurochemical Brain Changes Bipolar Depression
The purpose of the research is to study brain structure, function and chemistry of patients with bipolar disorder who are receiving quetiapine or lithium, in order to better understand who benefits from treatment and why they…
- Trial name
- NCT00608296
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Cincinnati
Endometrial Cancer, Obesity
Protein-Sparing Modified Fast Intervention for Weight Loss in Obese Endometrial Cancer Survivors
This pilot clinical trial studies protein-sparing modified fast (PSMF) intervention for weight loss in obese endometrial cancer survivors.
- Trial name
- NCT02135562
- Testing
- Dietary Intervention, Informational Material, Dietary Education
- Where
- 2 sites in United States
- Volunteers
- 11 people
- Sponsor
- Case Comprehensive Cancer Center
Exclusive Breastfeeding, Feeding Patterns
SPOON: Sustained Program for Improving Nutrition - Mexico
The primary goal of this study is to assess the impact of an innovative strategy to prevent undernutrition and obesity in early childhood in children 0-24 months in Mexico.
- Conditions
- Exclusive Breastfeeding, Feeding Patterns, Stunting, Obesity, Childhood
- Trial name
- NCT03752762
- Testing
- SQ-LNS, SPOON behavioral change strategy
- Where
- Mexico
- Volunteers
- healthy volunteers welcome
- Sponsor
- Inter-American Development Bank
Obesity, Hypertension
Improving Heart Health in Appalachia
Individuals in Appalachian Kentucky are vulnerable to cardiovascular disease (CVD) by virtue of having high rates of multiple CVD risk factors.
- Conditions
- Obesity, Hypertension, Hyperlipidemia, Depression
- Trial name
- HeartHealth (NCT01884246)
- Testing
- Self-care CVD risk reduction, Referral to primary care provider for CVD risk management
- Where
- United States
- Volunteers
- 330 people
- Sponsor
- Debra Moser
Bariatric Surgery Candidate
Clinical-functional Effects of Bariatric Surgery on the Musculoskeletal System in Relation to Bone Turnover.
By studying "in vivo" new possible predictive factors of increased bone turnover and risk of fractures after bariatric surgery, our study aims to improve health not only musculoskeletal but general of patients with severe…
- Trial name
- NCT06299085
- Testing
- 50 adult patients suffering from severe or morbid obesity, male and female, candidates for bariatric surgery.
- Volunteers
- 50 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Estimated Age Calculated Based on Modified Demirjian Method Using Mandibular Left Third Molar
Assessment of Reliability of Demirjian Formula for Age Estimation Using Mandibular Third Molar in a Sample of Egyptian Population Using CBT: a Cross-sectional Study
Aim: To assess the reliability of age estimation in Egyptian adolescents and young adults using mandibular third molar stages of calcification, based on the Demirjian method, on CBCT scans.
- Trial name
- NCT06232135
- Testing
- CBCT scan
- Where
- Egypt
- Volunteers
- 145 people
- Sponsor
- Cairo University
Heart Disease, Diabetes
Automated Guidance Tool for Medical Encounters Addressing Therapeutic Lifestyle Changes (AuGMEnT).
ABSTRACT Although most primary healthcare practitioners recognize the important relationship among nutrition, physical activity and health, few incorporate either dietary or physical activity counseling into routine practice.
- Trial name
- NCT00790491
- Testing
- guidance tool for providers for lifestyle changes
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Griffin Hospital
Chronic Hepatitis B
A Study to Evaluate the Safety, Tolerability and Pharmacokinetics and Pharmacodynamics of RO7062931in Healthy Volunteers and Subjects With Chronic Hepatitis B
This randomized study will be conducted in two parts to evaluate the safety, tolerability, pharmacodynamics, and pharmacokinetics of subcutaneous administration of RO7062931.
- Trial name
- NCT03038113
- Testing
- RO7062931, Immune Modulator
- Where
- 19 sites in Australia, Hong Kong and 5 more
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Obesity, Patient Education
Teaching Obesity Treatment Options to Adult Learners Trial
Obesity is the second leading cause of death in the U.S. The treatment of obesity and its related health issues, including cardiovascular disease and diabetes, exceeds $150 billion annually.
- Conditions
- Obesity, Patient Education, Weight Loss
- Trial name
- TOTAL (NCT03856320)
- Testing
- Educational Video
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- VA Office of Research and Development
Alzheimer's Disease, Huntington Disease
A Study In Healthy Volunteers To Estimate The Pharmacokinetics Of Four Modified-Release Formulations Of Dimebon (Latrepirdine)
This study will evaluate four different modified release formulation to estimate the amount of dimebon available to the body relative to the current dimebon formulation that is given three times a day.
- Trial name
- NCT00988624
- Testing
- Dimebon IR Tablet, Dimebon MR1, Dimebon MR2
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Pfizer
Metabolism; Disorder, Postprocedural, Resting Metabolic Rate
Changes in Resting Metabolic Rate Following Orthopedic Surgery
This project is intended to determine the magnitude and duration of RMR changes in patients receiving orthopedic surgery. The result will help to guide postoperative nutrition recommendations in patients receiving orthopedic…
- Conditions
- Metabolism; Disorder, Postprocedural, Resting Metabolic Rate, Post Operative Nutrition
- Trial name
- NCT06107959
- Testing
- Pre-surgical nutrition, hydration, RMR, and body composition assessments, Post-surgical nutrition, hydration, RMR and body composition assessments
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Kansas Medical Center
Prediabetic State, Gestational Weight Gain
Healthy Hearts: Leveraging the Diabetes Prevention Program to Decrease Health Disparities in Women of Reproductive Age
Nearly half of women have obesity and/or hypertension (HTN). Specific to women, pregnancy creates a vulnerable window for excess gestational weight gain (GWG), exacerbating intergenerational risks for obesity, HTN, type 2…
- Conditions
- Prediabetic State, Gestational Weight Gain, Hypertension, Overweight or Obesity
- Trial name
- HH (NCT05379296)
- Testing
- Diabetes Prevention Program Plus (DPP+), Diabetes Prevention Program (DPP)
- Sponsor
- The University of Texas Medical Branch, Galveston
Lifestyle-related Condition, COVID-19 Pandemic
Lifestyle Changes by the COVID-19 (Coronavirus Disease 2019) Pandemic in Children With Developmental Delays
To evaluate the lifestyle changes caused by the COVID-19 pandemic in children with developmental delays in Taiwan.
- Conditions
- Lifestyle-related Condition, COVID-19 Pandemic, Children With Developmental Delays
- Trial name
- COVID-19 (NCT05770362)
- Testing
- lifestyle questionnaire
- Where
- Taiwan
- Volunteers
- 260 people
- Sponsor
- Taipei Medical University
CABG-Patients
Changes in Cerebrovascular Reactivity During Cognitive Activation After Cardiopulmonary Bypass: Relation With Intraoperative Embolic Load and Postoperative Neuropsychological Dysfunctions
The study aims to evaluate neuropsychological disorders in CABG patients. Measurements are performed 1 day before, 6 days, 6 months and 3-5 years after the surgery.
- Trial name
- NCT00394108
- Testing
- Determination of neuropsychological status
- Where
- Belgium
- Volunteers
- 66 people
- Sponsor
- University Ghent
Cardiovascular Diseases (CVD), Metabolic Syndrome
Ambient Air and Noise Effect on Cardiovascular Health Risk and Lifestyle Intervention to Attenuate It (METSGREEN)
This study, combining both an observational study and an interventional clinical trial, aims to assess how exposure to ultrafine particulate matter (PM0.1) and noise pollution affects the risk of cardiovascular diseases and…
- Conditions
- Cardiovascular Diseases (CVD), Metabolic Syndrome, Air Pollution Exposure, Environmental Exposure
- Trial name
- METSGREEN (NCT07111208)
- Testing
- Green Space Activity Group - Daily Physical Activity, Mediterranean Diet Group - Dietary Intervention
- Where
- 2 sites in Lithuania
- Volunteers
- 180 people
- Sponsor
- Regina Grazuleviciene
Sedentary Lifestyle
The Psychology of Physical Activity
This study plans to learn more about psychosocial factors that contribute to adopting physical activity. The goal of this study is to improve upon existing theories of behavior change in order to help other people become more…
- Trial name
- NCT02538068
- Testing
- Daily Surveys, Random Surveys (8)
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Dietary Modification
Penn State ProduceRx Feasibility Study
To provide "prescriptions" for weekly Community Supported Agriculture (CSA) boxes of fruits and vegetables to patients, accompanied by nutritional education (e.g.
- Trial name
- NCT02794818
- Testing
- Produce boxes with nutritional education
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Obesity, Weight Loss
Efficacy of Diet and Hypnotic Suggestions or Telemedicine in Obesity Management
The aim of the study is the assessment of the effectiveness of medical nutrition therapy (MNT) among obese patients, including a well-balanced low-calories diet, an individual dietary counseling conducted by dietitians and…
- Trial name
- TASTY (NCT03811197)
- Testing
- Dietary counseling via face to face meeting, Telemedicine, Hypnotic Suggestions
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Warsaw University of Life Sciences
Vulvovaginal Atrophy, Dyspareunia
Vulvoscopy Changes of the Vulva, Vestibule and Vagina With Daily Ospemifene in Women With Dyspareunia From VVA
This is an unblinded study to be conducted at a single research center, San Diego Sexual Medicine. Subjects meeting inclusion and exclusion criteria will receive 60 mg ospemifene daily for twenty weeks.
- Trial name
- NCT02784613
- Testing
- Ospemifene
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Sue Goldstein
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