Clinical trials: Modification
Renal Dialysis, Hyperphosphatemia
Decreasing Intakes & Absorption of Phosphorus in Haemodialysis Patients Through Food Choices
Based on new evidence renal dietitians in Ireland are revising the diet sheet that is used to teach patients about reducing blood phosphate.
- Conditions
- Renal Dialysis, Hyperphosphatemia, Dietary Modification
- Trial name
- DIP HD (NCT03146923)
- Testing
- Current Low Phosphorus Diet Prescription, Modified Low Phosphorus Diet Prescription
- Where
- 10 sites in Ireland
- Volunteers
- 74 people
- Sponsor
- University College Cork
Obesity, Childhood, Asthma in Children
Asthma and Obesity Diet Versus Exercise
Obesity is recognized as a pro-inflammatory condition associated with multiple chronic diseases, including asthma. The specific mechanisms linking asthma and obesity remain hypothetical.
- Conditions
- Obesity, Childhood, Asthma in Children, Inflammatory Response, Metabolic Syndrome
- Trial name
- NCT03644355
- Testing
- Lifestyle counseling
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Chronic Obstructive Pulmonary Disease (COPD) With Cachexia
BYM338 in Chronic Obstructive Pulmonary Disease (COPD) Patients With Cachexia
This study will assess the pharmacodynamics, pharmacokinetics, safety and tolerability of BYM338 in patients with COPD and cachexia. The primary outcome will be a change in thigh muscle volume compared to placebo.
- Trial name
- NCT01669174
- Testing
- BYM338
- Where
- 9 sites in United States, Netherlands and 1 more
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Novartis Pharmaceuticals
Obesity, Polycystic Ovary Syndrome
Heat Therapy and Cardiometabolic Health in Obese Women
Traditional medical treatments are often based on research done exclusively in males, and recent research efforts in the physiology community have highlighted critical sex differences in disease presentation and progression.
- Conditions
- Obesity, Polycystic Ovary Syndrome, Prehypertension, PreDiabetes
- Trial name
- CMH (NCT03644524)
- Testing
- Heat therapy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Oregon
HIV Infections
A Study of Fuzeon (Enfuvirtide) With an Integrase Inhibitor Plus Optimized Background in Treatment-Experienced HIV-1 Infected Patients
This 2-arm study evaluated the efficacy and safety of Fuzeon with an integrase inhibitor in an expanded access program plus an optimized background antiviral regimen (AVR) in HIV-1 infected patients naive to Fuzeon and an…
- Trial name
- AMICI (NCT00488059)
- Testing
- enfuvirtide [Fuzeon], Optimized background ARV, Integrase inhibitor
- Where
- 43 sites in United States, Puerto Rico
- Volunteers
- 29 people
- Sponsor
- Hoffmann-La Roche
Type 1 Diabetes (T1D), Obesity (Disorder)
Vey Low-Energy Ketogenic Therapy in Adults With Type 1 Diabetes and Obesity on Intensive Insulin Therapy Using Advanded Hybrid Closed Loop System
Overweight and obesity are frequent in adults with type 1 diabetes (T1D), with prevalence exceeding 50% in recent studies. Excess weight in T1D is associated with higher cardiometabolic risk and therapeutic challenges, while…
- Trial name
- KET1D (NCT07185555)
- Testing
- VLEKT
- Where
- Italy
- Volunteers
- 14 people
- Sponsor
- Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari
Locally Advanced Oral Squamous Cell Carcinoma
Prospective Cohort Study on Oral Microbiome Changes in Patients With Locally Advanced Oral Squamous Cell Carcinoma Following Neoadjuvant Chemoimmunotherapy
Investigating the Relationship Between Oral Microbiome Alterations and Tumor Markers in Locally Advanced Oral Squamous Cell Carcinoma (LA-OSCC) After Neoadjuvant Chemoimmunotherapy: Implications for Therapeutic Efficacy…
- Trial name
- NCT07111455
- Where
- China
- Volunteers
- 32 people
- Sponsor
- Zhujiang Hospital
Intervention, Injury Prevention
Resistance Band Training Versus Nordic Hamstring Exercise on Hamstring Strength Among Football Players
The major aim of this project to compare the effects of Resistance band training and Nordic hamstring exercise on hamstring strength among football players.
- Trial name
- NCT05220215
- Testing
- Nordic Hamstring Exercise, Hamstring Curl with Resistance band
- Where
- Pakistan
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Weight Loss
A Trial of the Ideal Protein System Versus Low Fat Diet for Weight Loss
This study will examine whether, compared to a standard, low-fat, calorie-restricted diet intervention, the clinic-supported Ideal Protein weight loss method will result in greater weight loss and improvement in cardiometabolic…
- Trial name
- RENEWAL (NCT03515889)
- Testing
- Ideal Protein Weight Loss Method, Standard Weight Loss
- Where
- United States
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Tulane University
Xerostomia Following Radiotherapy, Xerostomia Following in Neck or Head After Cancer Surgery
Does Craniosacraltherapy Combined With Exercises That Focuses om Respiration and Posture in the Upper Body Have an Effect on Xerostomia and Other Late Sequelae on People Who Has Been Suffering From Cancer in Mouth and Throat?
The current study aims to assess the efficacy of manual treatment with craniosacral therapy of fascial tissue in throat, neck, cranial and mouth region, on radiation and/or surgery-induced salivary gland hypofunction and…
- Conditions
- Xerostomia Following Radiotherapy, Xerostomia Following in Neck or Head After Cancer Surgery, Other Late Sequelae Following Radiotherapy and Cancer Surgery in Neck or Head
- Trial name
- NCT05882890
- Testing
- Craniosacral Therapy, Exercices Targeting Upper Posture and Respiration
- Where
- 2 sites in Denmark
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Cathrine Rahbek
Contraception
Study to Evaluate the Safety and Efficacy of Two Contraceptive Vaginal Rings Delivering a Daily Dose of 1500 or 2500 μg of CDB-2914
The purpose of this study is to to determine pharmacodynamic effects of a vaginal ring delivering either 1,500 or 2,500 μg of CDB-2914 per day during 6 months of treatment on: 1. follicular function and inhibition of ovulation 2.
- Trial name
- NCT00791297
- Testing
- CDB-2914
- Where
- 3 sites in United States, Chile and 1 more
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Population Council
Overweight, Obesity
Sharing Digital Self-Monitoring Data With Others to Enhance Long-Term Weight Loss
Adults attempting weight loss through lifestyle modification (LM) typically find maintenance of behavior change difficult. Outcomes might be improved if participants are provided with sustained sources of accountability and…
- Trial name
- FitLink (NCT05180448)
- Testing
- Coach Share On, Group Share On, Friend/Family Share On
- Where
- United States
- Volunteers
- 321 people, healthy volunteers welcome
- Sponsor
- Drexel University
Hypertension, Dietary Modification
Hypertension Prevention Program, Implementation and Scale up- a Hybrid Effectiveness Implementation Study
This is an effectiveness-implementation study to assess the effectiveness of a peer-led multi-component lifestyle program that will aim to lower BP among pre-hypertensive individuals in Nepal.
- Conditions
- Hypertension, Dietary Modification, Health Behavior
- Trial name
- NCT04899648
- Testing
- Behavioral Intervention Group
- Volunteers
- 500 people
- Sponsor
- University of Washington
Multiple Sclerosis
Motor Training and White Matter in Multiple Sclerosis (MS)
In the current study the researchers will firstly investigate whether a bimanual coordination training protocol (20 min/day, for 8 consecutive weeks) correlates with changes in white matter architecture and improved upper-limb…
- Trial name
- NCT01279655
- Testing
- tDCS, Bimanual Training
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Kidney Failure, Chronic
Piloting an Intervention for Improving Treatment Adherence
Helping patient with long-term conditions to make informed decisions about adherence to their treatment is an important element in facilitating self-management.
- Trial name
- NCT02250235
- Testing
- Health risk information
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- University of Hertfordshire
Physical Therapy Techniques
Heat Transfer by Three Types of Packs and Its Implication on the Flexibility of the Lower Back
The purpose of this study is to compare the effects generated by the application of three different packs on the flexibility of the lower back of sedentary students.
- Trial name
- NCT02391376
- Testing
- moist heat pack; ;, seed pack, gel pack
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Universidad Católica del Maule
Neurosensory Function of Inferior Alveolar Nerve
Assessment of Nerve Function After Mandible Surgery With a Modified Bilateral Sagittal Split Osteotomy Technique
Several technical modifications based on the anatomical position of the neurovascular bundle and its bony mandibular canal have been developed, aiming to prevent injury to the intraalveolar nerve We hypothesized that the…
- Trial name
- NCT02634840
- Testing
- bilateral sagittal split osteotomy
- Volunteers
- 57 people
- Sponsor
- Chang Gung Memorial Hospital
Iron-deficiency
ProPBM : A Modified Patient Blood Management Protocol
The introduction of a modified perioperative patient blood management protocol with intravenous iron intervention for iron deficiency anaemic patients would reduce the need for allogenic blood transfusion and reduce perioperative…
- Trial name
- NCT03888768
- Testing
- MonoFer
- Where
- Malaysia
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Malaysia
Sjogren's Syndrome
Sjogrens Syndrome Measured by Ultrasound
Ultrasound study focused on salivary gland outcomes in Sjogren's subjects
- Trial name
- NCT03411850
- Testing
- Orencia
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Arthritis & Rheumatism Associates, P.C.
Infant, Premature, Diseases, Premature Birth of Newborn
Elevated Midline Positioning During Diaper Change in Preterm Infants
Diaper changing is one of the most frequent routine care procedures in the neonatal intensive care unit (NICU) and is known to cause physiological instability and behavioral stress responses in preterm infants.
- Conditions
- Infant, Premature, Diseases, Premature Birth of Newborn, Pain
- Trial name
- NCT07865897
- Testing
- 30-Degree Elevated Midline Positioning, Standard Lateral Position Diaper Change
- Volunteers
- 80 people
- Sponsor
- Akdeniz University
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