Clinical trials: Mohs Surgery
Surgical Wounds, Mohs Surgery
The Effects of Timolol On Healing and Cosmesis of Mohs Scalp Wounds: An Open Label Trial
The goal of this study clinical trial is to learn if topical timolol can accelerate healing and improve the cosmetic appearance of surgical wounds on the scalp following Mohs surgery.
- Trial name
- NCT07583862
- Testing
- Topical Timolol, Normal Saline
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Geisinger Clinic
Wound Healing, Mohs Micrographic Surgery
Topical 0.5% Timolol Solution for Healing Lower Extremity Wounds
Topical timolol, a β2-Adrenergic receptor (B2AR) antagonist, has demonstrated promise in wound healing over the past several years.
- Trial name
- NCT06941467
- Testing
- Timolol Maleate Solution, Standard of Care
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Pain, Procedural Pain
E-MOHS Trial of TENS and Vibration During Local Anesthesia
The E-MOHS Trial is a randomized controlled trial evaluating whether active vibration plus transcutaneous electrical nerve stimulation reduces pain during local anesthetic infiltration in adults undergoing Mohs micrographic…
- Conditions
- Pain, Procedural Pain, Local Anesthesia, Mohs Surgery
- Trial name
- E-MOHS (NCT07852455)
- Testing
- Active Vibration:TENS
- Where
- 3 sites in United States
- Volunteers
- 90 people
- Sponsor
- University of Minnesota
Mohs Micrographic Surgery, Cutaneous Malignancy
Efficacy of a Novel Cellular, Acellular, Matrix-like Product (CAMP) Plus Standard of Care Versus Standard of Care Alone in the Management of Post-Mohs Micrographic Surgery Defects.
A multicenter, prospective, randomized controlled clinical trial assessing the efficacy of a novel cellular, acellular, matrix-like product (CAMP) plus standard of care versus standard of care alone in the management of post-mohs…
- Conditions
- Mohs Micrographic Surgery, Cutaneous Malignancy, Mohs Surgical Defect
- Trial name
- BIOMOHS (NCT07695389)
- Testing
- Control Dressing + Standard of Care, CAMP + Standard of Care
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- BioLab Holdings
Postoperative Pain, Acute Pain
Suzetrigine Versus Standard Analgesia After Skin Cancer Surgery
This randomized clinical trial will compare suzetrigine with standard analgesia for postoperative pain management after skin cancer surgery.
- Conditions
- Postoperative Pain, Acute Pain, Skin Cancer, Cutaneous Malignancy
- Trial name
- NCT07843134
- Testing
- Suzetrigine, Acetaminophen Plus Ibuprofen
- Where
- 3 sites in United States
- Volunteers
- 230 people
- Sponsor
- University of Minnesota
Wound Healing, Mohs Micrographic Surgery
Hydrocolloid Dressings for Oculofacial Plastic and Reconstructive Wound Healing
This study aims to explore the use of a hydrocolloid dressing (DuoDERM EXTRA THIN) as an alternative to the current standard of care.
- Conditions
- Wound Healing, Mohs Micrographic Surgery, Oculofacial Reconstruction
- Trial name
- HCD Wound Heal (NCT07075159)
- Testing
- Hydrocolloid Wound Dressing
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Janice Hernandez, MD
Mohs Micrographic Surgery, Excision Margin
Efficacy and Safety of Topical Timolol in Secondary Intention Surgical Wounds Healing
The purpose of this research study is to evaluate the efficacy and safety of topical timolol 0.5% for secondary intention wound healing following 1) Mohs micrographic surgery, 2) standard surgical excision, OR 3)…
- Trial name
- NCT07384767
- Testing
- Timolol 0.5% Ophthalmic Solution
- Where
- 2 sites in United States
- Volunteers
- 220 people
- Sponsor
- University of California, Davis
Mohs Micrographic Surgery, Anesthesia, Local
Local Anesthetic Clinical Trial
To compare several local anesthetics when used during dermatological surgery.
- Trial name
- NCT07601750
- Testing
- Lidocaine, Bupivacaine Hydrochloride, Mepivacaine Hydrochloride
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Baylor Research Institute
Cutaneous Tumors, Mohs Micrographic Surgery
Suzetrigine vs Norco-postoperative Mohs Pain
To compare suzetrigine versus hydrocodone/acetaminophen for postoperative pain control following dermatologic surgery.
- Trial name
- NCT07575230
- Testing
- Norco 5Mg-325Mg Tablet, Suzetrigine
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Baylor Research Institute
Wounds and Injuries, Burns
Clinical Registry Collecting Real World Evidence on Wound Care Treatments
The proposed registry Sponsor (Siddhey LLC) will collect data on various wound treatments in real life settings. Data collection will facilitate the analysis of the safety and efficacy of wound treatments.
- Conditions
- Wounds and Injuries, Burns, Mohs Surgery, Diabetic Foot Ulcer Mixed
- Trial name
- SIDDX (NCT06328010)
- Testing
- Various types of wound care treatments
- Where
- 12 sites in United States
- Volunteers
- 5,000 people
- Sponsor
- Siddhey LLC
Suture, Suture Dermatologic
Effect of Petrolatum Coating on Fast-absorbing Gut Suture
This study is designed to evaluate the effect of using petrolatum to coat gut suture. This coating is commonly performed to make the suture more easy to handle; however, it was unknown if it affects the absorption rate of the…
- Conditions
- Suture, Suture Dermatologic, Mohs Micrographic Surgery, Suture Techniques
- Trial name
- NCT07127029
- Testing
- Petrolatum coating of fast-absorbing gut suture
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- San Antonio Uniformed Services Health Education Consortium
Wound Healing and Scar Quality Following Mohs Surgery and Excisional Dermatologic Surgery
Porcine Xenograft Versus Second Intention Healing
The purpose of this research study is to test whether it is better to allow patients with post- operative wounds on the legs to heal on their own without a covering or to use a porcine xenograft (skin graft that is made from pig…
- Trial name
- NCT03931746
- Testing
- Porcine xenograft
- Where
- 2 sites in United States
- Volunteers
- 14 people
- Sponsor
- Northwell Health
Mohs Micrographic Surgery
3D Printed Models in Mohs Micrographic Surgery
Patients undergoing Mohs micrographic surgery (MMS) frequently experience anxiety. It has been suggested that enhanced patient education prior to the procedure may decrease patient anxiety.
- Trial name
- NCT03461965
- Testing
- 3D printed model, Verbal Counselling
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Case Comprehensive Cancer Center
Skin Cancer, Non-Melanoma, Skin Cancer Melanoma
Interpolated Flap Study
The primary purpose of this study is to address the limited knowledge regarding patient well- being and nasal function after interpolated flap repair of post-Mohs surgical defects on the nose.
- Conditions
- Skin Cancer, Non-Melanoma, Skin Cancer Melanoma, Mohs Micrographic Surgery
- Trial name
- NCT04164550
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- University of Pennsylvania
Lidocaine, Bupivacaine
Comparing the Efficacy of Local Anesthetics in Mohs Surgery
Mohs surgery is a very effective option in removing non-melanoma skin cancers, as the tissue being removed is analyzed the same day.
- Conditions
- Lidocaine, Bupivacaine, Mohs Surgery, Anesthetic
- Trial name
- NCT03871478
- Testing
- Lidocaine, Bupivacaine, Lidocaine and Bupivacaine
- Where
- Canada
- Volunteers
- 105 people
- Sponsor
- Ottawa Hospital Research Institute
Scar, Surgical Wound
Correlation of Early Postoperative Scar Appearance With Long-term Scar Outcomes
A retrospective cohort study of early and late period postoperative scars using previously validated survey measures and clinical photographs.
- Conditions
- Scar, Surgical Wound, Quality of Life, Mohs Micrographic Surgery
- Trial name
- NCT04015453
- Testing
- Mohs micrographic surgery
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Abramson Cancer Center at Penn Medicine
Skin Cancer, Mohs Micrographic Surgery
Mohs Micrographic Surgery and Reconstruction in the Optum Insurance Claims Database
Mohs micrographic surgery (MMS) followed by skin reconstruction has been widely accepted for treatment of many skin cancers. To further characterize the trends in MMS and reconstruction for skin cancer, a retrospective analysis…
- Conditions
- Skin Cancer, Mohs Micrographic Surgery, Interpolated Flap Repair
- Trial name
- NCT04117373
- Where
- United States
- Sponsor
- University of Pennsylvania
Mohs Surgery
Briagen Observational Study
This research study is evaluating a study product called Briagen™ as a possible treatment for wound healing after Mohs procedure.
- Trial name
- BOS (NCT04090970)
- Testing
- Briagen
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Gemstone Biotherapeutics
Mohs Surgery
Impact of Videos on Patient Anxiety and Satisfaction
The purpose of this research is to look at how educational videos might affect patient satisfaction and anxiety before Mohs surgery day.
- Trial name
- NCT03485937
- Testing
- Pre-Operative Videos, verbal instructions, written instructions
- Sponsor
- Case Comprehensive Cancer Center
Mohs Surgery
Study of EB-001 in Facial Scar Reduction
This study will evaluate the safety and efficacy of EB-001 in improving wound healing and reducing scar formation in patients undergoing Mohs surgery for skin lesions in the forehead area following a single treatment of EB-001…
- Trial name
- NCT03346902
- Testing
- EB-001, 0.9% Sodium Chloride Injection
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Bonti, Inc.