Clinical trials: Montelukast
Healthy
Effects of Repeated Doses of Foliglurax on Drug Metabolizing Enzymes in Healthy Subjects
The purpose of this study is to help determine which types of drugs that may interact with foliglurax
- Trial name
- NCT04275115
- Testing
- Drug Cocktail, Foliglurax, midazolam iv
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- H. Lundbeck A/S
Respiratory Disorders
Relative Bioavailability Study of Two Montelukast Sodium (GW483100) 5 Milligrams (mg) Chewable Tablets and One Reference Montelukast Sodium 5 mg Chewable Tablet in Healthy Adult Subjects
This study is designed to estimate the bioavailability of montelukast from the 5 milligrams (mg) montelukast sodium (GW483100) test formulations relative to 5 mg montelukast sodium reference chewable tablets (innovator product).
- Trial name
- NCT02322671
- Testing
- Reference Montelukast, Test 1 Montelukast, Test 2 Montelukast
- Where
- India
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Respiratory Disorders, Asthma and Rhinitis
Bioequivalence of GW483100 10 Milligram (mg) Tablets in Healthy Subjects Under Fasting Conditions
This study is conducted to determine whether the test product (GW483100 10 mg containing montelukast sodium equivalent to 10 mg of montelukast) is bioequivalent to the reference montelukast sodium 10 mg tablets (innovator…
- Trial name
- NCT02658422
- Testing
- Test Montelukast, Reference Montelukast
- Where
- India
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Asthmatic Smokers, Non-asthmatic Smokers
The Effects of Montelukast on Smokers With Asthma
The purpose of this study is: 1. To compare neutrophilia, eosinophilic inflammatory markers and asthma symptom indices between smokers and non-smokers. 2.
- Trial name
- NCT00712335
- Testing
- Fluticasone Propionate, Montelukast, Salmeterol
- Where
- South Korea
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Inje University
Healthy
Drug-Drug Interaction Study: ASP2151 and Montelukast
CYP2C8 is involved in the metabolism of many drugs. So, it is important to assess in vivo the inhibitory effect of ASP2151 on that enzyme to determine any possible drug interactions.
- Trial name
- NCT02321748
- Testing
- Montelukast, ASP2151
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Maruho Europe Limited
Acne Vulgaris
Serum Intercellular Adhesion Molecule -1 in Acne Vulgaris Patients : Effect of Montelukast
The aim of this study is to: 1. Evaluation of serum soluble intercellular adhesion molecule-1 (sICAM-1) level in acne vulgaris and compare it to control group 2.
- Trial name
- NCT06340984
- Testing
- Montelukast 10 Mg Oral Tablet
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- South Valley University
Allergy
Effects of Intranasal Corticosteroid and Montelukast On Nasal Allergen Challenges*
This study will be a randomized, double blind, placebo-controlled, parallel group study and will include subjects with ragweed-induced seasonal allergic rhinitis.
- Trial name
- Roche (NCT01240889)
- Testing
- Fluticasone, Fluticason
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Creighton University
Food-drug Interaction
Effect of Pineapple Juice on the Pharmacokinetics of Celecoxib and Montelukast in Humans
Pineapple (Ananas comosus) is a tropical fruit that is rich in antioxidents, enzymes and vitamins. It is used worldwide due to their anti-inflammatory and analgesic properties.
- Trial name
- NCT04374981
- Testing
- Celecoxib 100mg, Montelukast 10mg
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Damanhour University
Rheumatoid Arthritis
Effects of Concomitant Administration of BMS-986195 on Methotrexate, Caffeine, Montelukast, Flurbiprofen, Omeprazole, Midazolam, Digoxin, and Pravastatin
Drug-drug interaction study in healthy men and women not of childbearing potential. Assess the effect of BMS-986195 on the pharmacokinetics of methotrexate, caffeine, montelukast, flurbiprofen, omeprazole, midazolam, digoxin, and…
- Trial name
- NCT03131973
- Testing
- BMS-986195, Methotrexate, Leucovorin
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
HIV Infections
Study on Effects of BMS-955176 on the Pharmacokinetics of Probe Substrates
The purpose of the study is to study the effects of BMS-955176 on the single-dose PK parameters of probe substrates caffeine, metoprolol, montelukast, flurbiprofen, omeprazole, midazolam, digoxin, and pravastatin
- Trial name
- NCT02578277
- Testing
- CYP and transporter probe substrates, BMS-955176, BMS-955176 plus CYP and transporter probe substrates
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- ViiV Healthcare
Asthma, Behavior Problem, Montelukast
To Investigate the Effect of Montelukast on Behavior Problems in Children With Asthma
The purpose of the study to investigate whether montelukast lead to behavior problems in children with asthma.
- Trial name
- NCT01818635
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Fatih University
Healthy
Bioequivalence Study of Montelukast Sodium Tablets 10mg Under Fed Condition
This is an open label, randomised, balanced, two-treatment, two-period, two-sequence, single dose, crossover, oral bioequivalence study.
- Trial name
- NCT01671722
- Testing
- Montelukast sodium
- Where
- India
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Dr. Reddy's Laboratories Limited
Wheezing
Wheeze and Intermittent Treatment
The clinical aim of this trial is to assess whether intermittent montelukast is an effective treatment strategy in preschool wheeze.
- Trial name
- WAIT (NCT01142505)
- Testing
- Mannitol, Montelukast
- Where
- United Kingdom
- Volunteers
- 1,358 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Exercise-Induced Bronchospasm
Effects of Montelukast on Occult Exercise-Induced Bronchospasm in Athletes
The purpose of this study is to determine if treatment of exercise-induced Bronchospasm with montelukast will help college athletes train more effectively and thus become more competitive in a non ergogenic manner.
- Trial name
- NCT00375232
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Indiana University
Healthy
Bioequivalence Study of Torrent Pharmaceutical Ltd.'s Montelukast Sodium 10mg Tablet Under Fasted Conditions
Objective: Primary objective of the present study was to compare the single dose bioavailability of Torrent's Montelukast Sodium 10 mg tablet and Innovator's(Merck)Singulair 10 mg tablet.
- Trial name
- NCT01928056
- Testing
- Torrent's Montelukast Sodium Tablets 10 mg
- Where
- India
- Volunteers
- healthy volunteers welcome
- Sponsor
- Torrent Pharmaceuticals Limited
Asthma and Allergic Rhinitis
Safety and the Pharmacokinetic Study of Characteristics of MKT-N2 (Montelukast) and Singulair® (Montelukast Sodium)to Treat Asthma
The Purpose of A center, Randomized, Open label, single dose, Placebo-controlled, 2-Treatment, 2-Way, 2-Period Crossover Study to Compare the Safety and the Pharmacokinetic Characteristics of MKT-N2 (Montelukast) and Singulair®…
- Trial name
- NCT02029313
- Testing
- Montelukast, Montelukast sodium
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- PharmaKing
Healthy Volunteers
Bioequivalence Study of Montelukast Sodium Oral Thin Film and Chewable Tablet in Fed Healthy Volunteers
This study aimed to evaluate the pharmacokinetic characteristics of montelukast sodium oral thin films and the bioequivalence between oral thin films and chewable tablets in healthy chinese volunteers under fed condition.
- Trial name
- NCT05531994
- Testing
- Montelukast sodium oral thin films with water (T), Montelukast sodium chewable tablets with water (R)
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Qilu Pharmaceutical Co., Ltd.
Asthma
Bioequivalency Study of Montelukast 10 mg Tablets Under Fed Conditions
The objective of this study was to prove the bioequivalence of Montelukast Tablet under fed conditions
- Trial name
- NCT01659918
- Testing
- Montelukast, Singulair
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Roxane Laboratories
Asthma
Bioequivalence Study of Montelukast 10 mg Tablets
The objective of this study was to confirm if two formulations of montelukast tablets are bioequivalent. Test product was Montelukast (10 mg tablets; GlaxoSmithKline) and reference product Singulair (10 mg tablets; Merck Sharp \&…
- Trial name
- NCT01943942
- Testing
- Montelukast 10 mg
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Drug-drug Interaction Study
A Phase 1 Drug-drug Interaction Study in Healthy Volunteers
This is an open-label, single-sequence, drug-drug interaction study in healthy male and female subjects. There is no formal research hypothesis to be statistically tested.
- Trial name
- DDI (NCT02227173)
- Testing
- BMS-986020, Montelukast, Flurbiprofen
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb