Clinical trials: Montelukast
Allergic Rhinitis
Montelukast and Fexofenadine Versus Montelukast and Levocetrizine Combination in Allergic Rhinitis
Objectives: Allergic Rhinitis (AR) is a global health problem. 10-25% of population worldwide is affected by AR. Oral/intranasal H1-antihistamine, decongestants, leukotriene receptor antagonists, intranasal corticosteroids are…
- Trial name
- NCT02551536
- Testing
- Montelukast, Fexofenadine, Levocetrizine
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Indira Gandhi Medical College, Shimla
Healthy
Bioequivalence Study of Montelukast Sodium Chewable Tablets 4mg and 5mg Under Fed Condition
This is an open label, randomised, balanced, two-treatment, two-period, two-sequence, single dose, crossover, oral bioequivalence study.
- Trial name
- NCT01674517
- Testing
- Montelukast sodium chewable tablets 4mg and 5mg
- Where
- India
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Dr. Reddy's Laboratories Limited
To Evaluate PSQ as Clinical Tool in the Decision Between Medical and Surgical Treatment for Adenotonsillar Hypertrophy, To Determine Clinical Response to Montelukast or Nasal Steroids Based on PSQ Results
Medical vs Surgical Treatment in OSA Among Children
Adeno-tonsillar hypertrophy causing OSA are treated surgically however, over the last years it has been shown that montelukast or nasal steroidal spray can significantly improve symptoms, adenoid size, and polysomnographic…
- Trial name
- NCT05651750
- Testing
- Montelukast, Fluticasone Furoate
- Where
- Israel
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Asthma
Bioequivalence Study of Montelukast 10 mg Tablets
The objective of this study was to confirm if two formulations of montelukast tablets are bioequivalent. Test product was Montelukast (10 mg tablets; GlaxoSmithKline) and reference product Singulair (10 mg tablets; Merck Sharp \&…
- Trial name
- NCT01943942
- Testing
- Montelukast 10 mg
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Chronic Otitis Media With Effusion, Conductive Hearing Loss
Montelukast for Children With Chronic Otitis Media With Effusion (COME): A Double-blind, Placebo-controlled Study
The purpose of our double-blind, placebo controlled study is to test the hypothesis that montelukast therapy might be associated with improved hearing in certain sub populations of children suffering from OME.
- Trial name
- COME (NCT01967498)
- Testing
- Montelukast
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Asthma
Bioequivalency Study of Montelukast 10 mg Tablets Under Fed Conditions
The objective of this study was to prove the bioequivalence of Montelukast Tablet under fed conditions
- Trial name
- NCT01659918
- Testing
- Montelukast, Singulair
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Roxane Laboratories
Asthma, Seasonal Allergic Rhinitis
Adolescent and Adult Subjects With Asthma and Seasonal Allergic Rhinitis Receiving Advair Diskus or Placebo
The four respiratory drugs being researched in this study have been approved by the US Food and Drug Administration (FDA) and are currently available by prescription at your drug store.
- Trial name
- NCT00385463
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Creighton University
Asthma, Behavior Problem, Montelukast
To Investigate the Effect of Montelukast on Behavior Problems in Children With Asthma
The purpose of the study to investigate whether montelukast lead to behavior problems in children with asthma.
- Trial name
- NCT01818635
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Fatih University
Healthy
Bioequivalence Study of Montelukast Sodium Oral Granules 4mg Under Fed Condition
This is an open label, randomised, balanced, two-treatment, two-period, two-sequence, single dose, crossover, oral bioequivalence study.
- Trial name
- NCT01691469
- Testing
- Montelukast sodium
- Where
- India
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Dr. Reddy's Laboratories Limited
Healthy
Bioequivalence Study of Torrent Pharmaceutical Ltd.'s Montelukast Sodium Chewable 5mg Tablet Under Fed Conditions
Objective: Primary objective of the present study was to compare the single dose bioavailability of Torrent's Montelukast Sodium chewable 5mg tablet and Innovator's(Merck)Singulair chewable 5mg tablet.
- Trial name
- NCT01931514
- Testing
- Torrent's Montelukast Sodium chewable Tablets 5mg, Singulair® (Montelukast Sodium) Chewable Tablets 5mg
- Where
- India
- Volunteers
- healthy volunteers welcome
- Sponsor
- Torrent Pharmaceuticals Limited
Food-drug Interaction
Effect of Pineapple Juice on the Pharmacokinetics of Celecoxib and Montelukast in Humans
Pineapple (Ananas comosus) is a tropical fruit that is rich in antioxidents, enzymes and vitamins. It is used worldwide due to their anti-inflammatory and analgesic properties.
- Trial name
- NCT04374981
- Testing
- Celecoxib 100mg, Montelukast 10mg
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Damanhour University
Chronic Periodontitis
Role of Leukotriene Receptor Antagonists in Treatment of Chronic Periodontitis
The adjunctive use of Leukotriene Receptor Antagonist (Montelukast) along with scaling and root planing in patients with chronic periodontitis leads to host inflammatory response modulation and decrease in serum C reactive…
- Trial name
- NCT02014532
- Testing
- Montelukast
- Where
- India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tatyasaheb Kore Dental College
Asthma
Analysis of Exhaled Breath by Biosensors in Adults With Asthma
The aim of this study is to investigate the pattern of organic volatile compounds (VOCs) in the exhaled breath detected by biosensors in adults with persistent mild asthma.
- Trial name
- NCT00819676
- Testing
- analysis of exhaled breath by biosensors, measurement of exhaled nitric oxide
- Where
- Italy
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Catholic University of the Sacred Heart
Upper Respiratory Tract Infection
Montelukast as Prophylaxis for Upper Respiratory Tract Infections in Children: a Randomised, Double-blind, Placebo-controlled Study
Viral upper respiratory tract infection (URI) is one of the most common diseases among toddlers and pre-school children.Complete and effective prevention measures for URI are currently unavailable.
- Trial name
- NCT00551382
- Testing
- Muntelukast
- Where
- 3 sites in Israel
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Healthy
Bioequivalence Study of Torrent Pharmaceutical Ltd.'s Montelukast Sodium 10mg Tablet Under Fasted Conditions
Objective: Primary objective of the present study was to compare the single dose bioavailability of Torrent's Montelukast Sodium 10 mg tablet and Innovator's(Merck)Singulair 10 mg tablet.
- Trial name
- NCT01928056
- Testing
- Torrent's Montelukast Sodium Tablets 10 mg
- Where
- India
- Volunteers
- healthy volunteers welcome
- Sponsor
- Torrent Pharmaceuticals Limited
Acne Vulgaris
Serum Intercellular Adhesion Molecule -1 in Acne Vulgaris Patients : Effect of Montelukast
The aim of this study is to: 1. Evaluation of serum soluble intercellular adhesion molecule-1 (sICAM-1) level in acne vulgaris and compare it to control group 2.
- Trial name
- NCT06340984
- Testing
- Montelukast 10 Mg Oral Tablet
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- South Valley University
Asthma
Genotype Stratified Pharmacokinetic Study of Montelukast
Leukotriene receptor antagonists (LTRAs) are frequently prescribed to reduce the symptoms associated with asthma. Singulair (montelukast), manufactured by Merck, is a popular LTRA, however its effectiveness varies greatly between…
- Trial name
- GSPOM (NCT01086527)
- Testing
- 10 mg tablet of montelukast (Singulair)
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Asthma
Bioequivalency Study of Montelukast 10 mg Tablets Under Fasted Conditions
The objective of this study was to prove the bioequivalence of Montelukast Tablet under fasted conditions
- Trial name
- NCT01659931
- Testing
- Montelukast, Singulair
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Roxane Laboratories
Allergic Rhinitis
Comparison of Montelukast and Azelastine in Treatment of Moderate to Severe Allergic Rhinitis
Comparison of Montelukast and Azelastine In treatment of Allergic Rhinitis Allergic intent is one of the most common diseases of the respiratory system that has a devastating effect on the quality of life.
- Trial name
- NCT04561687
- Testing
- Montelukast, Azelastine, Budesonide
- Where
- Iran
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Shiraz University of Medical Sciences
Anemia, Sickle Cell, Sleep-Disordered Breathing
SMILES: Study of Montelukast in Sickle Cell Disease
Sickle cell disease (SCD) is a genetic blood condition causing long term health problems including pain and brain problems which affect quality of life.
- Trial name
- SMILES (NCT04351698)
- Testing
- Montelukast
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust