Clinical trials: Mood Change
Cognitive Change
Cognitive and Cerebral Blood Flow Effects of Zanthozylum Armatum Fruit Extract in Healthy Adults Aged 30 - 55
Zanthozylum armatum (Z. armatum)-otherwise known as Nepalese pepper, or timut-is an perennial shrub found in India and across Southeast Asia. Preparations of the bark, fruit and seeds of Z.
- Trial name
- NCT03673930
- Testing
- Zanthozylum armatum
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Aging, Protein Metabolism
Metabolite Changes Following Consumption Of Different Protein Drinks In Singapore Older Adults
The study aims to investigate the acute effects of different protein sources (i.e., casein, whey, soy) on metabolomic profiles (e.g., amino acids in the blood), along with other outcomes such as cognitive function, mood, and…
- Trial name
- NCT06956131
- Testing
- Casein Protein Isolate Drink, Whey Protein Isolate Drink, Soy Protein Isolate Drink
- Where
- Singapore
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Mood Change, Emotion Regulation
Interoception and Emotion Regulation
The goal of this observational study is to examine the role of interoception in emotion regulation of negative mood in healthy individuals. Participants will fulfill several questionnaires and perform the Heartbeat Counting Task.
- Trial name
- INTEROEMOTION3 (NCT05684614)
- Testing
- Negative mood induction procedure, Spontaneous emotion regulation task, Positive mood induction procedure
- Where
- 3 sites in Spain
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Mood, Cognitive Change
Investigating the Effects of Dietary Phospholipids on Measures of Human Brain Health and Psychological Wellbeing
The aim of this study is to investigate the effects of 6- and 12-week supplementation of a bioactive whey protein concentrate drink containing dairy phospholipids on cognitive function and mood in healthy young to middle aged…
- Conditions
- Mood, Cognitive Change, Well-Being, Psychological
- Trial name
- NCT06107075
- Testing
- Active
- Where
- United Kingdom
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Northumbria University
LPS, Mood Disorders
Resistance Exercise Plus Vinegar Ingestion on Biomarkers in Healthy Adults
Given its capacity to stimulate exercise-induced neuroplasticity at lower doses compared to aerobic exercise, resistance exercise has become the top-recommended rehabilitation approach for individuals with neurocognitive…
- Conditions
- LPS, Mood Disorders, Cognitive Change
- Trial name
- NCT06437405
- Testing
- Vinegar liquid, vinegar pill
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Behavioral Problem, Irritable Mood
Stop, Focus, Plan, and Change: Predicting Parent and Child Responses to a Brief, Telehealth Parent Training
This study will look at who does not improve after doing a behavioral parent training program briefly through telehealth. It will also study ways to make the intervention better for those that do not improve.
- Conditions
- Behavioral Problem, Irritable Mood, Parenting, Stress
- Trial name
- NCT06505980
- Testing
- Brief Behavioral Parenting Program
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Overweight, Pregnancy
Effects of Antenatal Nutrition Counseling on Maternal and Infant Outcomes
This randomized controlled trial evaluated whether individualized antenatal nutrition counseling provided between 24 and 36 weeks of gestation could improve maternal dietary quality, dietary inflammatory potential, gestational…
- Trial name
- NCT07845773
- Testing
- Dietitian-Led Nutrition Education and Counseling
- Where
- Cyprus
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Subthreshold Depression, Exercise
The Effect of Exercise on Cognition and Preventing Depression in Young People
It is estimated that approximately 30% of child and adolescents manifest subthreshold depression (including other specified depressive disorder and unspecified depressive disorder), which can further develop into major depression…
- Conditions
- Subthreshold Depression, Exercise, Clinically-well, Cognitive Change
- Trial name
- NCT04816617
- Testing
- Aerobic exercise intervention, Psycho-education
- Where
- China
- Volunteers
- 628 people, healthy volunteers welcome
- Sponsor
- Guangzhou Psychiatric Hospital
Bipolar Disorder, Covid19
Genetics of COVID-19 Risks & Resilience in Bipolar Disorder
BIPGEN is a cross-sectional study on the genetics of bipolar disorder. As a subproject of BIPGEN, BIP-COVID is a cross-sectional genetics study about risks \& resilience in the COVID-19 (Coronavirus disease) pandemic in bipolar…
- Conditions
- Bipolar Disorder, Covid19, Stress
- Trial name
- BIPCOVID (NCT04972708)
- Testing
- Cross-sectional genetics study
- Where
- Austria
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Major Depressive Disorder 1
Cultural Adaptation of EMDR for Major Depressive Disorder and Compaire Its Online and Face-to-Face Testing
The present study aims to develop a culturally and methodologically adapted EMDR therapy protocol, determine its treatment fidelity, and then clinically test its efficacy in the treatment of Major Depressive Disorder in Pakistan…
- Trial name
- EMDR (NCT06439043)
- Testing
- EMDR Psychotherapy, Online EMDR Psychotherapy
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Khushal Khan Khattak Univeristy, Karak, Pakistan
Emotional Instability, Borderline Personality
Exploring a New Measure of Emotion Regulation
Background: Emotion regulation has been established as an important concept in mental health research across a range of different diagnoses.
- Trial name
- EMER (NCT04779619)
- Testing
- Online self-report questionnaire completion
- Where
- United Kingdom
- Volunteers
- 903 people, healthy volunteers welcome
- Sponsor
- Sussex Partnership NHS Foundation Trust
Daily Self-weighing, Daily Temperature-taking
Self-Weighing: an Ecological Momentary Assessment
The primary objective of this study is to experimentally test the momentary and more distal psychological effects of daily self weighing as compared to an active control group.
- Trial name
- SWEMA (NCT03273491)
- Testing
- daily self-weighing, daily temperature-taking
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Nicotine Dependence
IV Nicotine Induced Changes in Hormone Function, Mood States and Behavior
Clinical studies are proposed to analyze the interactions between nicotine, alterations in endocrine hormones, mood and cardiovascular measures.
- Trial name
- NCT01589055
- Testing
- Intravenous Nicotine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mclean Hospital
Major Depressive Disorder, Inflammation
The Relations Among Endotoxin, Inflammatory Cytokines, Cognitive Markers and Brain MRI Changes in Subjects With Depressive Disorder
Major depressive disorder (MDD) is a chronic mental illness, with 60% lifetime risk of recurrence after the first MDD episode. Despite available treatment options for MDD, only about half to two-thirds of patients respond to…
- Conditions
- Major Depressive Disorder, Inflammation, Cognitive Dysfunction, Endotoxemia
- Trial name
- NCT06203015
- Testing
- The Cambridge Neuropsychological Test Automated Battery., Venous blood samples, brain MRI
- Where
- 2 sites in Lithuania
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Lithuanian University of Health Sciences
Neurologic Disorders, Schizophrenia
Characterization of High-Level Cognitive Impairments in Patients With Neuropsychiatric Disorders
Neuropsychiatric disorders are extremely common, severe, and disabling conditions. In the field of psychiatry, they notably include schizophrenia, mood disorders (depressive and bipolar disorders), autism spectrum or…
- Conditions
- Neurologic Disorders, Schizophrenia, Bipolar Disorder (BD), Depressive Disorder
- Trial name
- COGPSY (NCT07295652)
- Testing
- Cognitive assessment, Brain MRI (optional), Electroencephalography (optional)
- Where
- 3 sites in France
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier St Anne
Mood
Effects of Theobromine and Caffeine on Mood, Cognition and Blood Pressure
The purpose of this study was to measure potential mood, cognition and blood pressure effects of theobromine and caffeine in healthy women
- Trial name
- NCT01288547
- Testing
- theobromine, Caffeine, caffeine + theobromine
- Where
- Netherlands
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Unilever R&D
Overweight/Obesity (BMI: 27 and 35 kg/m2)
tVNS and Obesity-related Mechanisms
The overarching goal of the project is to assess whether transcutaneous Vagus Nerve Stimulation (tVNS) induced reduction of central and peripheral inflammation is associated with tVNS induced changes in mood and motivation in a…
- Trial name
- NCT06954844
- Testing
- Transcutaneous non-invasive vagus nerve stimulation (tVNS), Low intensity stimulation
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Bonn
Alcohol Craving, Mood Changes
A Dose Response Effect of Atomoxetine to the Acute Effects of Alcohol
This two-stage study will examine the effects of a 5 day course of atomoxetine (placebo, 40, 60 or 80 mg/day; Strattera) (a selective NE transporter (NET) inhibitor) on alcohol-elicited craving and sensitivity to alcohol.
- Trial name
- ATX_COMT (NCT01408589)
- Testing
- Atomoxetine, Strattera
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Boulder
Memory Deficits, Mood Change
The Effects of Microbiological Spectrum Changes to Improve Cognitive Health in Aging Population
The goal of this project is to develop probiotic dietary supplements intended for the elderly, which can modify the composition of the intestinal microbiota typically occurring in the aging population.
- Conditions
- Memory Deficits, Mood Change, Gut Health, Aging Problems
- Trial name
- CleverAgeBiota (NCT05051501)
- Testing
- Probiotics C2P
- Where
- 2 sites in Czechia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health, Czech Republic
Obesity, Eating Behavior
The Effects of Chia on Overweight/Obese Women
The purpose of the study is to examine the effect of chia seed consumption on body composition, blood pressure, blood glucose, satiety, mood, joint pain, and dietary displacement in overweight and obese females (18-45years).
- Conditions
- Obesity, Eating Behavior, Mood, Glucose
- Trial name
- NCT03233906
- Testing
- Chia Seeds- Salvia Hispanica
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- California State Polytechnic University, Pomona