Clinical trials: Morbid Obesity
Obesity, Morbid, Metabolic Syndrome
Biometabolic Outcomes After Weight Loss Surgery: An Individualized Approach
Variable outcomes after weight loss surgery are likely attributable to complex, poorly understood mechanisms. Due to the significant impact that morbid obesity has on a patient's health, successful management of obesity and its…
- Conditions
- Obesity, Morbid, Metabolic Syndrome, NASH - Nonalcoholic Steatohepatitis
- Trial name
- NCT04841057
- Testing
- 50 cm BP limb length, 100 cm BP limb length, 150 cm BP limb length
- Where
- United States
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Obesity, Morbid
The Effect of Timing of Intravenous Paracetamol Administration on Post-surgical Pain
This study is designed as a population-based prospective randomized cohort study. A prospective cohort of patients admitted to laparoscopic sleeve gastrectomy due to morbid obesity
- Trial name
- NCT03221998
- Testing
- IV paracetamol, IV saline (NaCl 0.9 %)
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Steatohepatitis, Morbid Obesity
Transoral Endoscopic Liver Biopsy During Laparoscopic Gastric Bypass
This research is being done to evaluate the ability to obtain a liver sample using upper endoscopy rather than through a laparoscopic procedure.
- Trial name
- NCT00512512
- Testing
- Transoral Endoscopic Liver Biopsy
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Obesity
Deep Transcranial Magnetic Stimulation (TMS) With Paired Associative Stimulation (PAS) for the Treatment of Food Addiction in Obesity
The neurobiological underpinnings of obesity point to brain asymmetry in cortical and deeper brain regions. Furthermore, chemical, structural and functional imbalance in cortical and sub-cortical brain regions alters reward…
- Trial name
- FAOB (NCT02761369)
- Testing
- A multi-channel deep TMS device with an H-coil (Brainsway Ltd)
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Obesity, Weight Loss
Bariatric Embolization Trial for the Obese Nonsurgical
The purpose of this study is to assess the safety profile of bariatric embolizations and confirm published reports of sustained post-procedural weight loss, and pathologically assess post-procedural metabolic effects.
- Conditions
- Obesity, Weight Loss, Body Weight, Morbid Obesity
- Trial name
- BET-ON (NCT03601273)
- Testing
- Left gastric artery embolization
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Physical Inactivity, Obesity, Morbid
Investigation of the Effectiveness of Whatsapp-Based Physical Activity Incentive Program in Morbidly Obese Individuals
The limited number of studies on the effectiveness of physical activity incentive programs for morbidly obese individuals in the literature shows the need in this area.
- Trial name
- NCT05519423
- Testing
- Physical Activity Incentive Program
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Morbid Obesity, Metabolically Healthy Obesity
Establishment of the Human Intestinal and Salivary Microbiota Biobank - Obesity
This is a prospective, clinical, multicentre study aimed to collect biological samples and study microbiota from subjects with morbid obesity, metabolically healthy obesity and from healthy volunteers.
- Trial name
- BIOMIS-Endo (NCT04698135)
- Testing
- Biological samples collection, Questionnaire, Medical/laboratory examinations
- Where
- Italy
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari
Diabetes
Personalised Medicine for Morbid Obesity
The prevalence of morbid obesity (BMI > 40 kg/m2) is increasing rapidly in the UK, but the investigators lack a coherent strategy for detailed assessment and treatment of the individuals affected, who are at high risk of…
- Trial name
- NCT01365416
- Where
- United Kingdom
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Obesity, Morbid, Eating Disorder Symptom
Mindfulness Based Eating Awareness Training for Bariatric Surgery Patients
The purpose of this study is to evaluate the effects of Mindfulness Based Eating Awareness Training (MB-EAT) for patients who have had bariatric surgery on their weight and mental and physical health compared to patients who do…
- Trial name
- MB-EAT (NCT03488966)
- Testing
- Mindfulness Based Eating and Awareness Training
- Where
- Canada
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Morbid Obesity
Sleeve-gastrectomy Efficacy in Morbid Obese Patient With a Focus on the Role of Inflammation
Despite the wide range of studies concerning the positive effects of bariatric surgery on metabolic state of morbid obese patient, it is necessary to further investigate the specific role of the "sleeve-gastrectomy" intervention…
- Trial name
- NCT03559842
- Where
- Italy
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University Of Perugia
Pain, Postoperative, Obesity, Morbid
Effect of Bilateral Rectointercostal Fascial Plane Block on Postoperative Pain After Laparoscopic Sleeve Gastrectomy
This randomized controlled study aims to evaluate the effectiveness of the bilateral rectointercostal fascial plane (RIB) block for postoperative pain management in patients undergoing laparoscopic sleeve gastrectomy.
- Conditions
- Pain, Postoperative, Obesity, Morbid, Laparoscopic Sleeve Gastrectomy (LSG), Opioid Use
- Trial name
- NCT07253610
- Testing
- Bilateral Rectointercostal Fascial Plane Block, Intravenous Patient-Controlled Analgesia (IV PCA) with Morphine
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Samsun University
Physical Capacity
Lifestyle Intervention and Physical Capacity in Patients With Morbid Obesity
Lifestyle intervention and physical capacity in patients with morbid Obesity (LEICO)
- Trial name
- LEICO (NCT03593798)
- Testing
- Lifestyle
- Where
- 2 sites in Norway
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sykehuset i Vestfold HF
Morbid Obesity
Single Incision Laparoscopic Gastric Banding Versus Conventional Five Port Laparoscopic Gastric Banding
Gastric banding has been shown to significantly reduce weight and has been approved as a treatment of morbid obesity. The standard laparoscopic operation requires five small incisions for the introduction of instruments and the…
- Trial name
- NCT01039077
- Testing
- Laparoscopic gastric banding
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Severe Obesity, Hypoxia
Use of Non-Invasive Positive Pressure Ventilation in Patients With Severe Obesity Undergoing Upper Endoscopy Procedures
The study evaluated the effect of non-invasive positive pressure ventilation (NIPPV) to decrease the incidence of desaturation events in patients with severe obesity undergoing upper endoscopy.
- Trial name
- NCT03529461
- Testing
- Non-invasive positive pressure ventilation through nasal mask, Rescue non-invasive positive pressure ventilation through nasal mask, Secondary rescue maneuvers
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Bristol Hospital
Obesity, Morbid, Bariatric Surgery
Photographic Food Recognition and Meal Size Estimation Before and After Roux-en-Y Gastric Bypass
Direct measurements of changes in food selection in humans after RYGB have been limited by the unreliability of patients, which poses significant methodological and conceptual challenges to researchers and study design.
- Conditions
- Obesity, Morbid, Bariatric Surgery, Roux-en-Y Gastric Bypass, Food Preferences
- Trial name
- NCT04600596
- Testing
- Recording of food intake.
- Where
- Switzerland
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Marco Bueter
Morbid Obesity, Bariatric Surgery Candidate
Physical Activity in Bariatric Patients
The aim of the current study was to explore the effect of a 6-months motivational physical activity intervention (MPAI) on different psychosocial variables (e.g.
- Trial name
- NCT03666481
- Testing
- Motivational Physical Activity Intervention (MPAI)
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidad Miguel Hernandez de Elche
Obesity, Weight Loss
Self-compassion and Nutrition (SCAN) Study
The purpose of this study is to examine the feasibility of two approaches for improving long-term weight loss success among individuals with severe obesity.
- Trial name
- NCT04289636
- Testing
- Behavioral weight loss program, Self-compassion, Nutrition and cooking education
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
Intubation;Difficult, Morbid Obesity
Comparison of Intubation Success Rates of 3 Different Laryngoscope Blade Types in Morbidly Obese Patients
Reusable laryngoscope blades, which are the most commonly used devices for airway management, have been reported to be frequently contaminated and a possible source of infection.
- Trial name
- NCT04477148
- Testing
- endotracheal intubation
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- Turkish Society of Anesthesiology and Reanimation
Morbid Obesity
Micafungin Pharmacokinetics in Obese Patients
Because micafungin is generally well tolerated and appears to have limited interaction with other drugs, it is a potential important agent in the treatment of invasive fungal infections.
- Trial name
- MICADO (NCT03102658)
- Testing
- Micafungin
- Where
- 2 sites in Netherlands
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Obesity, Morbid
Preoxygenation With Optiflow™ in Morbidly Obese Patients is Superior to Face Mask
Optiflow™ may provide an opportunity to prolong apnea time in the morbidly obese patient population. This study will examine whether Optiflow can do this, and compare the pre-oxygenation with Optiflow to the pre-oxygenation…
- Trial name
- NCT03009877
- Testing
- Optiflow F&P 850™ System, facemask, Rocuronium
- Volunteers
- healthy volunteers welcome
- Sponsor
- Montefiore Medical Center