Clinical trials: Morbidity, Multiple
Bronchopulmonary Dysplasia
The Role of Volatile Organic Compounds (VOCs), Airway Mucins and the Microbiome in the Early Prediction of Bronchopulmonary Dysplasia (BPD)
Bronchopulmonary dysplasia (BPD), the most common respiratory complication of extremely preterm birth, significantly impacts healthcare with high morbidity and mortality rates.
- Trial name
- INFANCY (NCT06342752)
- Testing
- Breath test, Throat swabs, Placental samples
- Where
- Belgium
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Old Age, Family Members
The Chit-Chat Educational Intervention to Promote Advance Care Planning in the Community
The purpose of this study is to estimate the effect size of the Chit-Chat intervention on ACP engagement among family members of older adults with multi-morbidity.
- Trial name
- NCT06296719
- Testing
- Chit-Chat
- Where
- Hong Kong
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Aging, Hiv
2nd AC+: New Village Model
This study evaluates implementation of the Village Model to support older people living with HIV.
- Conditions
- Aging, Hiv, Loneliness, Social Isolation
- Trial name
- 2nd AC+ (NCT04323176)
- Testing
- Village Model implementation
- Where
- 2 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Postural Tachycardia Syndrome
Periaqueductal Gray-vagus Nerve Interface Malfunction Explain the Natural History With Its Numerous Co-morbidities?
This study is being conducted to see how people with Postural tachycardia syndrome (POTS) make sense of the things they see. The information may help doctors to learn more about how the different parts of people's brains…
- Trial name
- NCT05618054
- Testing
- Looming task
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Hypertension, Diabetes Mellitus
Cohort Study on Patient Outcomes, Effectiveness and Cost-effectiveness of Intervention Programmes for DM/HT Patients
Objectives: To determine the outcome trajectories of patients with hypertension (HT) and/or diabetes mellitus (DM), and evaluate the long-term effectiveness and cost-effectiveness of the Risk Assessment and Management Programmes…
- Conditions
- Hypertension, Diabetes Mellitus, Cardiovascular Diseases, Morbidity, Multiple
- Trial name
- TRACC (NCT04302974)
- Testing
- Different structures and processes of primary care management strategies, Multi-disciplinary Risk Factor Assessment and Management Programmes for diabetes (RAMP-DM), Multi-disciplinary Risk Factor Assessment and Management Programmes for hypertension (RAMP-HT)
- Where
- China
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Covid19, Morbidity
BCG to Reduce Absenteeism Among Health Care Workers During the COVID-19 Pandemic
The COVID-19 pandemic challenges available hospital capacity. Strategies to protect health care workers (HCW) are desperately needed.
- Conditions
- Covid19, Morbidity, Absenteeism
- Trial name
- EDCTP (NCT04641858)
- Testing
- BCG-Denmark, Saline
- Where
- 2 sites in Guinea-Bissau, Mozambique
- Volunteers
- 668 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Breast Cancer, Shoulder
Morbidity After Diagnosis and Treatment of Breast Cancer Patients
This study will examine the frequency and severity of problems in women with breast cancer for 2 years following initial medical treatment, including: Physical impairments, such as loss of strength or flexibility, increased…
- Conditions
- Breast Cancer, Shoulder, Lymphedema, Fatigue
- Trial name
- NCT00027118
- Where
- United States
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Degeneration Muscle, Multiple Morbidities
Cardiopulmonary Training in the Victims With Multiple Morbidities by Application of Novel Heart Rate Sensing Clothes
Investigators assume that the wearable clothes can be applied to home-based health care and integrated into a case management model through telehealthcare.
- Conditions
- Degeneration Muscle, Multiple Morbidities, Heart; Complications
- Trial name
- NCT04022590
- Testing
- E-clothes, Healthy consultation
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shang-Lin Chiang
POTS - Postural Orthostatic Tachycardia Syndrome
Does a Periaqueductal Gray-vagus Nerve Interface Malfunction Explain the Nat hx With Its Numerous Co-morbidities?
Postural tachycardia syndrome (POTS) is a common and disabling disorder among adolescents. No epidemiologic data exist to support the often cited 0.5 to 2% prevalence.
- Trial name
- NCT06616363
- Testing
- Questionnaires to be competed, Provide list of medication and lifetime events, Use phone App to record new life events
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Syphilis
Multi-site Study of Rapid Diagnostic Syphilis Assays
The performance of an investigational immunochromatographic strip (ICS) test for the diagnosis of syphilis is compared with the Abbott Laboratories Determine ICS test.
- Trial name
- NCT00300534
- Testing
- Abbott Laboratories Determine test for syphilis, Investigational syphilis immunochromatographic strip test
- Where
- 5 sites in United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Covid19, Thymic Hypoplasia
Is Thymus Size of Infants Who Born to COVID-19 Positive Mothers Associated With Neonatal Morbidities?
COVID-19 infected pregnant women is thought to have variable degrees of inflammatory response against the disease. Investigators of present study, suggested that fetuses are affected from the possible fetal inflammatory syndrome…
- Trial name
- NCT04470739
- Testing
- chest x-ray
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
COVID-19, SARS-CoV 2 Infection, Health Disparities
EMPOWER - BAME vs COVID
The COVID-19 virus pandemic has massively affected us all. Moreover, there is a disproportionately high number of COVID-19 severe infections and deaths in British Black, Asian and minority ethnic (BAME) patients.
- Trial name
- NCT04399733
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- Future Genetics Limited
Gingival Recession, Generalized
Comparison of De-Epithelialized Gingival Graft With or Without Platelet Rich Fibrin in Multiple Gingival Recessions
The aim of this study is to compare the clinical efficacy and patient reported outcome measures of de-epithelialized gingival graft (DGG) with or without platelet rich fibrin on treatment of multiple adjacent gingival recessions…
- Trial name
- NCT06509867
- Testing
- DGG, Platelet rich fibrin
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Atrial Fibrillation, Coronary Heart Disease
EMPOWER-1: A Multi-site Clinical Cohort Research Study to Reduce Health Inequality
Health inequality and genetic disparity are a significant issue in the United Kingdom (UK). This study focuses on diseases that are associated with significant morbidity and mortality in the UK, and specifically examines the…
- Conditions
- Atrial Fibrillation, Coronary Heart Disease, Cardiovascular Diseases, Heart Failure
- Trial name
- EMPOWER (NCT03987633)
- Where
- United Kingdom
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- Future Genetics Limited
COVID-19, Non-specific Effects of Vaccines
Using BCG Vaccine to Protect Health Care Workers in the COVID-19 Pandemic
Background: The COVID-19 pandemic challenges the available hospital capacity, and this will be augmented by absenteeism of healthcare workers (HCW).
- Conditions
- COVID-19, Non-specific Effects of Vaccines, Morbidity, Absenteeism
- Trial name
- NCT04373291
- Testing
- BCG-Denmark, Saline
- Where
- Denmark
- Volunteers
- 1,293 people, healthy volunteers welcome
- Sponsor
- Bandim Health Project
Sarcopenia, Aging
STRIDE: Strength of The Calf Muscles and Their Role In Declining Effectiveness of Movement With Aging
The calf muscles (plantarflexors) are the most important muscles for walking, running and daily activities. Weakness of these muscles through aging and disease significantly impact a person's ability to walk and complete daily…
- Conditions
- Sarcopenia, Aging, Muscle Weakness or Atrophy, Frailty
- Trial name
- STRIDE (NCT07726498)
- Testing
- No intervention (observational study)
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Maternal Malnutrition, Growth Failure
Women First: Preconception Maternal Nutrition
Multi-country three-arm, individually randomized, non-masked, controlled trial to ascertain the benefits of ensuring optimal maternal nutrition before conception and providing an evidence base for programmatic priority directed…
- Conditions
- Maternal Malnutrition, Growth Failure, Mortality, Morbidity
- Trial name
- WF (NCT01883193)
- Testing
- Comprehensive Maternal Nutrition Intervention
- Where
- 4 sites in Democratic Republic of the Congo, Guatemala and 2 more
- Volunteers
- 7,374 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Child Malnutrition, Infant Morbidity
Effectiveness of Nutritional Supplementation in Preventing Malnutrition in Children With Infection in Karamoja, Uganda
The purpose of this study is to determine whether 14 days nutritional supplementation with Ready to use therapeutic Food (RUTF) or micronutrients alone to children having an infection will prevent malnutrition and reduce the…
- Trial name
- MSF-nutcon03 (NCT01497236)
- Testing
- Dietary Supplement: Nutrition supplement with RUTF or MNP
- Where
- Uganda
- Volunteers
- 2,202 people, healthy volunteers welcome
- Sponsor
- Medecins Sans Frontieres, Spain