Clinical trials: Morning Sickness
Hyperemesis Gravidarum
Pregnancy Specific Nausea Questionnaire (PUQE) Translated and Tested in Norwegian
Nausea in early pregnancy (emesis gravidarum) is very common but most often self-limiting. Hyperemesis gravidarum; where nausea and vomiting is severe and protracted is potentially dangerous for the woman and her foetus and…
- Trial name
- PUQE-N (NCT01836835)
- Testing
- Pregnancy Unique Questionnaire of Emesis (PUQE), 24 hours self-reported nutritional intake form
- Where
- 2 sites in Norway
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Nausea and Vomiting
Prevalence of Hyperemesis Gravidarum
Nausea and vomiting during pregnancy represent one of the most common symptoms of pregnancy, affecting 35 to 91% of women. Most often, the symptoms are mild, without impairment of quality of life and disappear at the end of the…
- Trial name
- PHyperEG1 (NCT06415084)
- Where
- France
- Volunteers
- 619 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Hyperemesis Gravidarum, Pregnancy
Effects Of Emotional Freedom Technique and Hypermesis Gravidarum
The purpose of this clinical study is to determine whether EFT (Emotional Freedom Techniques) is effective in alleviating nausea and vomiting in pregnant women with hyperemesis.
- Trial name
- PREGNANCY (NCT06442813)
- Testing
- EFT GROUP
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Morning Sickness
A Multicenter Trial of the Efficacy and Safety of Diclegis® for Nausea and Vomiting of Pregnancy in Pregnant Adolescents
The primary objective of this study is to compare the efficacy of Diclegis for the treatment of nausea and vomiting of pregnancy (NVP) in pregnant adolescents aged 12 to 17 years with placebo.
- Trial name
- PED-301 (NCT02045901)
- Testing
- Diclegis
- Where
- 8 sites in United States
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Duchesnay Inc.
Hyperemesis Gravidarum
The Effect of Guided Imagery and Diaphragmatic Breathing Exercise in Pregnant Women With Hyperemesis Gravidarum
Objective: The aim of the researchers is to determine the effects of guided imagery and diaphragmatic breathing exercise application on nausea, vomiting severity, and anxiety level in pregnant with hyperemesis gravidarum.
- Trial name
- NCT05829473
- Testing
- Breathing Exercise Group, Guided Imagery Group
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Gaziantep Islam Science and Technology University
Hyperemesis; Gravidarum, With Dehydration
Endothelial Dysfunction in Hyperemesis Gravidarum
The purpose of the study is to determine serum inflammatory adhesion molecules levels in hyperemesis gravidarum
- Trial name
- NCT02989337
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Kayseri Education and Research Hospital
Morning Sickness
The Efficacy and Safety of Bonjesta® for Nausea and Vomiting of Pregnancy in Pregnant Adolescents
The primary objective of this study is to compare the efficacy of Bonjesta for the treatment of nausea and vomiting of pregnancy (NVP) in pregnant adolescents aged 12 to 17 years with placebo.
- Trial name
- NCT05289557
- Testing
- Bonjesta
- Where
- 10 sites in United States
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- Duchesnay Inc.
Pregnancy, Pregnancy Complications
PregSource: Crowdsourcing to Understand Pregnancy
PregSource uses a crowd-sourcing approach, asking pregnant women to enter information regularly and directly about their pregnancies throughout gestation and the early infancy of their babies into online surveys and trackers via…
- Conditions
- Pregnancy, Pregnancy Complications, Morning Sickness, Diabetes, Gestational
- Trial name
- PregSource (NCT02577536)
- Testing
- No Interventions
- Where
- United States
- Volunteers
- 2,359 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Hyperemesis Gravidarum - Severe, Resistin
First Trimester Resistin Levels in HG
This cross-sectional case-control study was conducted in Tuzla State Hospital Obstetrics Clinic in Turkey. The study evaluated 400 pregnant women during their first trimester of pregnancy.
- Conditions
- Hyperemesis Gravidarum - Severe, Resistin, Gestational Diabetes Mellitus (GDM)
- Trial name
- NCT06757374
- Testing
- Resistin
- Where
- Turkey (Türkiye)
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Hyperemesis Gravidarum, Nausea Gravidarum
Validating the Effect og Ondansetron and Mirtazapine in Treating Hyperemesis Gravidarum
The aim is to investigate the efficacy of mirtazapine and ondansetron as treatment for hyperemesis gravidarum(HG). The setup is a double-blind multicenter trial where patients suffering from HG will be randomized to treatment…
- Conditions
- Hyperemesis Gravidarum, Nausea Gravidarum, Vomiting of Pregnancy
- Trial name
- VOMIT (NCT03785691)
- Testing
- Mirtazapine, Ondansetron
- Where
- 7 sites in Denmark
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Nordsjaellands Hospital
Hyperemesis Gravidarum
The Effect of Mint Flavored Chewing Gum on Hyperemesis Gravidarum Nausea Vomiting Severity, Coping With Stress and Anxiety Level in Pregnants With Hyperemesis Gravidarum
In the research planned as a randomized controlled study, the experimental groups will be administered routine hyperemesis gravidarum (HG) treatment as well as chewing mint-flavored gum, while the control group will only receive…
- Trial name
- NCT06266819
- Testing
- chewing gum
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Ordu University
Hyperemesis Gravidarum
The Association of Helicobacter Pylori in the Pathogenesis of Hyperemesis Gravidarum in Pregnant Women
The purpose of this study to explore the association between Hyperemesis Gravidarum in pregnant women and Helicobacter pylori infection.
- Trial name
- AOHPIPOHGIPW (NCT02830321)
- Testing
- helicopacter pylori stool antigen test (CER TEST BIOTEC)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- rasha fawzy abd el kader
Hyperemesis Gravidarum, Pregnancy
Nutritional Markers in Normal and Hyperemesis Pregnancies
This study evaluate the rate of nausea and nutritional status in patients with hyperemesis gravidarum (severe nausea and vomiting in pregnancy) and healthy pregnant women using a questionnaire (PUQE-score), self-reported…
- Trial name
- PUQE-M (NCT02619188)
- Testing
- PUQE-form inclusion, Nutritional form inclusion, Blood sampling inclusion
- Where
- Norway
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Hyperemesis Gravidarum
Hyperemesis Gravidarum Risk Reduction With Metformin
The goal of this clinical trial is to evaluate whether daily oral metformin extended-release (metformin-XR), taken prior to and in early pregnancy, can reduce the risk and severity of Hyperemesis Gravidarum (HG), a severe nausea…
- Trial name
- NCT07129473
- Testing
- Metformin Extended Release Oral Tablet
- Where
- 2 sites in United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Hyperemesis Gravidarum, Temperament
Assessment of the Relationship Between Affective Temperament and the Severity of Nausea and Vomiting in Early Pregnancy
In this study, the investigators aimed to research the relationship between affective temperament with the severity of the symptoms of nausea and vomiting in early pregnancy.
- Conditions
- Hyperemesis Gravidarum, Temperament, Morning Sickness
- Trial name
- NCT02541682
- Testing
- TEMPS-A (Temperament Evaluation of Memphis, Pisa, Paris and San Diego Auto-questionnaire)
- Where
- Turkey (Türkiye)
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Mustafa Kemalpasa Government Hospital
Hyperemesis Gravidarum, Pregnant With Complication
Pepsinogen-1 Serum Levels in Hyperemesis Gravidarum
In this study, the investigators planned to investigate maternal serum pepsinogen-1 (MSPG-1) levels in pregnant women with severe hyperemesis gravidarum (HG) and pregnant women without severe HG.
- Trial name
- NCT06581796
- Testing
- pepsinogen-1
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ankara Etlik City Hospital
Hyperemesis; Gravidarum, With Dehydration, Gestational Diabetes
Hyperemesis Gravidarum and 75 Gram Oral Glucose Tolerance Test
Hyperemesis gravidarum (HEG) is not only nausea and vomiting of pregnancy, but it is also a clinical syndrome including endocrine and metabolic complications.
- Trial name
- NCT02963753
- Volunteers
- 560 people, healthy volunteers welcome
- Sponsor
- Kayseri Education and Research Hospital
Hyperemesis Gravidarum, Pregnancy Related
Gallbladder Functions & Serum Cholecystokinin Levels in Women Diagnosed With Hyperemesis Gravidarum
This study evaluates the gallbladder functions and serum cholecystokinin levels in pregnant women diagnosed with hyperemesis gravidarum.
- Trial name
- NCT03950167
- Where
- Turkey (Türkiye)
- Volunteers
- 325 people, healthy volunteers welcome
- Sponsor
- Müge Keskin
Hyperemesis Gravidarum
Hyperemesis Gravidarum and Osteoporosis
Hyperemesis Gravidarum (HG) is a common disorder for hospitalization in the first trimester of pregnancy and related to protracted vomiting and nausea. It can be accompanied by ketonuria, dehydration and weight loss.
- Trial name
- NCT03127293
- Testing
- DEXA
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Adana Numune Training and Research Hospital
Morning Sickness
Freezie Remedy to Alleviate Morning Sickness
The primary objective of this study is to assess the effectiveness of Lillipops in the improvement of morning sickness symptoms.
- Trial name
- NCT01668940
- Testing
- Lillipops Iced Soothies (4 flavours), Mr. Freeze Freezies, Lillipop Iced Soothies (Ginger flavour)
- Where
- Canada
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children