Clinical trials: Morphine
Abdominal Surgery, Thoracic Surgery
Parent/Nurse Controlled Analgesia in the Neonatal Intensive Care Unit
The aim of this study is to examine the safety and effectiveness of 2 morphine delivery systems for post-surgical neonates. The investigators hypothesize that this study will be feasible to conduct, and that neonates receiving…
- Trial name
- PNCA (NCT01823497)
- Testing
- Morphine
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Medical College of Wisconsin
Cancer Pain, Opioid Use
Epidural Association of Morphine and Ropivacaine for Cancer Pain Treatment
In 2012, more than 14 million cases of cancer were diagnosed worldwide, with the forecast for 2025 exceeding 20 million. Pain is the most critical symptom that accompanies cancer.
- Conditions
- Cancer Pain, Opioid Use, Cost Analysis, Palliative Care
- Trial name
- NCT05558397
- Testing
- Interventional Group (Epidural morphine), Control Group (Oral morphine)
- Where
- Brazil
- Volunteers
- 32 people
- Sponsor
- Universidade Federal de Alfenas
Abdominal Muscles/Ultrasonography, Adult
TAP Catheters Versus Intrathecal Morphine for Cesarean Section
Morphine, when given as part of spinal anesthesia, is associated high incidence of nausea and pruritus, which may affect quality of recovery.
- Conditions
- Abdominal Muscles/Ultrasonography, Adult, Anesthetics, Local/Administration & Dosage, Ropivacaine/Administration & Dosage
- Trial name
- NCT01593280
- Testing
- TAP catheter, intrathecal morphine
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Stamford Anesthesiology Services, PC
Pain, Postoperative
Morphine-Sparing Effect And Safety Of Parecoxib Administered Intravenously For The Treatment Of Postoperative Pain
To validate the morphine-sparing effect and safety of parecoxib administered intravenously for the treatment of Chinese subjects with postoperative pain following gynecological or orthopedic surgery.
- Trial name
- NCT00143169
- Where
- 8 sites in China
- Volunteers
- 220 people
- Sponsor
- Pfizer
Dialysis Access Malfunction
The ReModel IHC Study for ESRD Patients
There will be two phases of this study. The phases of this study may occur simultaneously. In Phase I, eligible subjects will be asked to acutely wear the Alio Medical RMS SmartPatch during regularly scheduled dialysis sessions.
- Trial name
- NCT05039541
- Testing
- Alio Device
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Alio, Inc.
Postoperative Pain
Open-Label Placebo Treatment for Acute Postoperative Pain
This study is to evaluate whether the amount of morphine intake in acute postoperative pain following minimally invasive Transforaminal Lumbar Interbody Fusion (TLIF) can be decreased with an Open-Label Placebo (OLP) intervention…
- Trial name
- OLP-POP (NCT04339023)
- Testing
- treatment as usual
- Where
- Switzerland
- Volunteers
- 76 people
- Sponsor
- University Hospital, Basel, Switzerland
Osteoarthritis, Knee
Postoperative Pain Control After Periarticular Injection During Total Knee Arthroplasty
This study will evaluate the use of a local injection around the knee (periarticular) during total knee replacement (TKR) surgery to see if it reduces postoperative pain levels.
- Trial name
- NCT02570503
- Testing
- Ropivacaine, Ketorolac, Clonidine
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Severe Traumatic Pain, Numeric Pain Rating Scale > 5 / 10
Intra Nasal Sufentanil Versus Intravenous Morphine for Acute Severe Traumatic Pain Analgesia in Emergency Setting
Intranasal (IN) administration of opiates is an appealing non-invasive way of treating acute traumatic pain in prehospital and Emergency departments (ED).
- Trial name
- ALGOFINE-2 (NCT02095366)
- Testing
- Morphine, Sufentanil
- Where
- 6 sites in France
- Volunteers
- 194 people
- Sponsor
- University Hospital, Grenoble
Intubation Complication
Comparison of Hemodynamic Changes With Morphine Versus Esmolol During Induction of Anaesthesia
Comparing hemodynamic changes with morphine versus esmolol as an adjuvant agent during induction of Anaesthesia
- Trial name
- NCT06065956
- Testing
- Intravenous morphine
- Where
- Pakistan
- Volunteers
- 110 people
- Sponsor
- Pakistan Navy Station Shifa Hospital
Anesthesia, Analgesia
Subcostal Approach to Anterior Quadratus Block Versus Thoracic Paravertebral Block for Laparoscopic Nephrectomy
In this study, it was aimed to evaluate the effects of subcostal anterior quadratus lumborum block (S-QLB3) and thoracic paravertebral block (TPVB) on postoperative acute pain scores and opioid consumption in the first 24 hours…
- Conditions
- Anesthesia, Analgesia, Acute Pain, Patient Controlled Analgesia
- Trial name
- NCT05191966
- Testing
- Subcostal Anterior Quadratus Lumborum Block, Thoracic Paravertebral Block
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Ondokuz Mayıs University
Laparoscopic Gynecological Surgery
Effect of Intrathecal Morphine on Quality of Recovery After Laparoscopic Gynecological Surgery
Minimally invasive gynecologic surgery has become the standard approach for the treatment of benign and malignant gynecologic diseases, offering the advantages of reduced surgical trauma and faster recovery.
- Trial name
- NCT07322029
- Testing
- Intrathecal morphine group, TAPB, Intrathecal saline injection
- Where
- China
- Volunteers
- 252 people
- Sponsor
- Sun Yat-sen University
Anesthesia
Decreased Neuraxial Morphine After Cesarean Delivery
The purpose of this study is to compare 50mcg to 150mcg morphine in epidural for the goal of decreasing side effects of medication with lower dose in patients who receive a QL block
- Trial name
- NCT04279054
- Testing
- Morphine Sulfate 150 mcg, Morphine Sulfate 50mcg
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- University of Alabama at Birmingham
Cesarean Section
Role of Prophylactic Antiemetics in Women Receiving Intrathecal Morphine and Lipophilic Opioids Added to Bupivacaine for Cesarean Section
Because the majority of Caesarean deliveries are performed under neuraxial anaesthesia, Intrathecal morphine has become the gold standard for post-Caesarean delivery analgesia.
- Trial name
- NCT06704139
- Testing
- Morphine - .25 mg, fentanyl + morphine, Ondansetron + Dexamethasone
- Volunteers
- 100 people
- Sponsor
- Assiut University
Abdominal Pain
Patient Satisfaction With Subdissociative Dose Ketamine Versus Morphine for Emergency Department Pain Control
The proposed research will be a single blinded (patient) randomized controlled prospective trial of adult patients receiving treatment for moderate to severe abdominal pain to test the hypothesis that patient satisfaction with…
- Trial name
- NCT04698772
- Testing
- Ketamine, Morphine
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- CHRISTUS Health
Post Operative Pain
Effects of a Combination of IV-PCA With Continuous IV Infusion of MO, Versus IV-PCA MO on Postoperative Pain
After major surgery, such as abdominal or thoracic surgery, the majority of patients experience moderate to severe pain that may not be optimally controlled.
- Trial name
- NCT00849719
- Testing
- a combination of PCA MO and continuous infusion of MO, PCA MO only
- Where
- Israel
- Volunteers
- 150 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Pain, Postoperative
Preventive Skin Analgesia With Lidocaine Patch 5% for Controlling Post-thoracotomy Pain
Thoracotomy is one of the most painful surgical incision. Uncontrolled acute post-thoracotomy pain reducing deep breathing exercises and secretion clearance increased the incidence of postoperative pulmonary complications…
- Trial name
- NCT02751619
- Testing
- Lidocaine patch 5%
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Campania Luigi Vanvitelli
Anesthesia
Impact of Dexamethasone Added to Intra-articular Morphine and Bupivacaine for Post-operative Analgesia After Knee Arthroscopy
A randomized double-blinded clinical trial was carried out on 40 patients undergoing knee arthroscopy. Patients were divided randomly into two equal groups.
- Trial name
- NCT04790292
- Testing
- group M, group MD
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Age Problem, Abdominal Cancer
Dosage of Epidural Morphine in Elderly Patients
This a clinical trial that evaluates the efficacy and safety of three different doses of morphine, namely 1.5 mg, 3 mg and 4.5 mg, via the epidural route regarding reducing pain in elderly patients after a cancer surgery in the…
- Trial name
- NCT04316871
- Testing
- 1.5 mg of Morphine Sulfate, Normal saline, 3 mg of Morphine Sulfate
- Where
- Egypt
- Volunteers
- 96 people
- Sponsor
- Assiut University
Postoperative Pain
An Efficacy and Safety Study to Compare Morphine 6-glucuronide (M6G) and Morphine in Patients Suffering With Post-Operative Pain for at Least 24 Hours
To compare the incidence and severity of nausea in the study treatment groups, during the 18-hour period starting 6 hours after titration to pain relief; following confirmation of the assumption of non-inferiority between the two…
- Trial name
- NCT01082471
- Testing
- Morphine 6-glucuronide, Morphine
- Where
- 7 sites in Czechia, France and 4 more
- Volunteers
- 517 people
- Sponsor
- Paion UK Ltd.
Knee Disease, Arthritis Knee
Intraosseous Morphine in Primary TKA
The research team wants to investigate if an intraosseous injection (directly into the bone marrow) of morphine during primary total knee replacement helps with post-operative pain following primary total knee replacement…
- Conditions
- Knee Disease, Arthritis Knee, Pain, Acute
- Trial name
- NCT04388111
- Testing
- Morphine
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- The Methodist Hospital Research Institute