Clinical trials: Morton Toe
Neuroma
ALGRX 4975 in the Treatment of Patients With Morton's Neuroma
Subjects will have painful primary or post-operative intermetatarsal neuroma. Study drug or placebo will be injected into the space containing the neuroma.
- Trial name
- NCT00130962
- Testing
- ALGRX 4975
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- AlgoRx Pharmaceuticals
Painful Intermetatarsal Neuroma (Morton's Neuroma)
A Study to Evaluate the Efficacy and Safety of CNTX-4975 in Subjects With Painful Intermetatarsal Neuroma (Morton's Neuroma)
Study 4975-MN-202 is a double-blind, placebo-controlled, parallel group, single-injection study in which subjects will be randomized to receive three doses of CNTX-4975 or placebo injected into the intermetatarsal space around a…
- Trial name
- NCT02283957
- Testing
- CNTX-4975
- Where
- 16 sites in United States
- Volunteers
- 119 people
- Sponsor
- Centrexion Therapeutics
Morton Neuroma
Morton's Neuroma: Manipulation Versus Steroid Injection
This study compares manipulative therapy to steroid injection in the treatment of Morton's Neuroma.
- Trial name
- NCT05707572
- Testing
- methylprednisolone, manual manipulation
- Where
- United Kingdom
- Volunteers
- 62 people
- Sponsor
- Dundee Podiatry Clinic
Morton Neuroma
Comparative Effectiveness of Cryoablation Versus Steroid and Lidocaine Alone for Treatment of Morton's Neuroma
Morton's neuroma is a benign thickening involving the plantar interdigital nerve, most common in middle aged women. Morton's neuroma is one of the most frequent diagnoses seen in the investigators podiatry clinic and is difficult…
- Trial name
- NCT05501262
- Testing
- Cryoablation, Nerve block
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Plantar Fasciitis of Both Feet, Metatarsalgia
A Test of Efficacy and Foot Position Alteration in Patients Wearing Good Feet Arch Supports for the Treatment of Pain
This study is a single armed prospective case series designed to evaluate the efficacy of treating common structural-related foot ailments (i.e.
- Conditions
- Plantar Fasciitis of Both Feet, Metatarsalgia, Morton Neuroma, Hallux Valgus Deformity
- Trial name
- Good Feet (NCT07103070)
- Testing
- Arch supports
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Massachusetts General Hospital
Foot Morphology, Morton Toe
Morton's Toe and Neuromuscular Performance
This cross-sectional study compared vastus lateralis contractile properties and drop jump reactive performance between female football players with (MF) and without (NMF) Morton's toe morphology.
- Conditions
- Foot Morphology, Morton Toe, Neuromuscular Properties
- Trial name
- NCT07588048
- Where
- Turkey (Türkiye)
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Giresun University
Intermetatarsal Bursitis, Morton Neuroma
US and MRI of the Forefoot: Intermetatarsal Bursitis or Morton's Neuroma
The aim of this study is to investigate the incidence of intermetatarsal bursitis and Morton's neuroma in patients with metatarsalgia (i.e. pain in the forefoot) and control subjects by diagnostic imaging with ultrasound and MRI.
- Conditions
- Intermetatarsal Bursitis, Morton Neuroma, Intermetatarsal Neuroma
- Trial name
- NCT05685160
- Testing
- MRI with contrast, Ultrasound
- Where
- Denmark
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Morton's Neuroma
Resiniferatoxin for the Management of Refractory Morton s Neuroma Pain
Morton s neuroma is an irritation of the nerves that affect the feet. People with this condition may have burning or shooting pain in the balls of their feet. They may also have numbness in adjacent areas.
- Trial name
- NCT05695339
- Testing
- Resiniferatoxin
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Neuroma, Human Forefoot
Morton's Neuroma: Manipulation Versus Steroid Injection
The aim of this study is to establish which of two treatment options is the preferred intervention in the treatment of Morton's Neuroma. A randomised controlled trial shall be performed.
- Trial name
- NCT02304094
- Testing
- methylprednisolone, Manual manipulation
- Where
- United Kingdom
- Volunteers
- 64 people
- Sponsor
- Queen Margaret University
Morton Neuroma
Insole on Morton's Neuroma
Objective: The aim of the present study was to assess the effectiveness of insole with metatarsal support on pain in patients with Morton's neuroma and the impact of this insole on function, load distribution in the plantar…
- Trial name
- NCT03511677
- Testing
- Insole
- Volunteers
- 72 people
- Sponsor
- Federal University of São Paulo
Carpal Tunnel Surgery, Trigger Finger Disorder
NAC-REPAIR for Post-surgical Pain
This pilot asks whether peri-operative N-acetylcysteine (NAC) improves recovery after common outpatient hand/foot-ankle surgery-specifically, does NAC reduce pain and opioid use and enhance function by modulating…
- Conditions
- Carpal Tunnel Surgery, Trigger Finger Disorder, De Quervain Syndrome, Guyon's Canal
- Trial name
- NCT07227649
- Testing
- NAC
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Arizona
Restless Legs Syndrome
Neuroma Injections to Treat Restless Legs Syndrome - RCT
The purpose of this study is to determine whether, in a randomized, placebo-controlled trial, restless legs syndrome (RLS) can be caused by pinched and damaged foot nerves called neuromas.
- Trial name
- NCT00656110
- Testing
- equal parts of 0.5% plain Marcaine and 2% lidocaine mixed with 0.8 mg Depo-medrol/4% absolute alcohol in a total injection volume of 1 ml, Normal saline - 1ml
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Lowcountry Infectious Diseases
Morton Neuroma, Radriofrequency
Radiofrequency Before to Surgical Removal of a Recalcitrant Morton´s Neuroma
The purpose of this study is to perform a radiofrequency procedure prior to the removal of morton's neuroma. This procedure would be performed to check in which percentage of the nerve ablation has been performed, and whether the…
- Trial name
- REQUIEM (NCT05550831)
- Testing
- Radiofrequency
- Where
- Spain
- Volunteers
- 34 people
- Sponsor
- Universidad de Extremadura
Morton's Neuroma
Study to Evaluate the Safety and Tolerability of CNTX-4975 in Subjects With Painful Intermetatarsal Neuroma (Morton's Neuroma)
The purpose of this study is to confirm that the local anesthetic applied to subjects with Morton's Neuroma satisfactorily mitigates procedure pain and ensures that post-procedure discomfort or pain will not result in bias or…
- Trial name
- NCT02550756
- Testing
- CTNX-4975
- Volunteers
- 11 people
- Sponsor
- Centrexion Therapeutics
Morton's Neuroma
Comparison of Alcohol and Steroid Injection for Treating Morton's Neuroma
Interdigital neuroma is a painful forefoot disorder characterized by plantar pain and toe paresthesias thought to result from entrapment of the interdigital nerve by the overlying transverse metatarsal ligament.
- Trial name
- NCT00284583
- Testing
- Injection of Steroid into Foot, Injection of Alcohol into Foot, Injection of Lidocaine into Foot
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Brown University
Morton Neuroma
Is Ultrasonography Comparable to MRI for the Detection of Morton Neuroma of the Foot?
Patients with Morton neuroma of the foot will undergo either ultrasonography or MRI. The results will be compared. In case of surgery, the pathology report will be compared with the ultrasonographic or MRI findings.
- Trial name
- NCT00284414
- Testing
- Ultrasonography or MRI
- Sponsor
- University Hospital, Ghent
Morton's Neuroma
A Study to Evaluate the Safety and Efficacy of CNTX-4975 in Subjects With Painful Intermetatarsal Neuroma (Morton's Neuroma)
Subjects who have completed study 4975-MN-202 will be eligible to receive open-label treatment with CNTX-4975 200 µg in study 4975-MN-203 if they meet the inclusion/exclusion criteria.
- Trial name
- NCT02678793
- Testing
- CNTX-4975
- Where
- 10 sites in United States
- Volunteers
- 67 people
- Sponsor
- Centrexion Therapeutics
Morton's Neuroma, Pain Management
Cryoanalgesia for the Treatment of Pain in Subjects With Morton's Neuroma
This is a Proof-of-Concept Trial to define the safety, efficacy and feasibility of a cryoanalgesic device (iovera°®) for the treatment of pain in subjects diagnosed with Morton's Neuroma, who have failed conservative therapies.
- Trial name
- NCT05604144
- Testing
- Cryoanalgesia (iovera°®)
- Where
- 2 sites in United States
- Volunteers
- 5 people
- Sponsor
- Northern California Research Trials, Inc.
Morton Neuroma
Blind and Ultrasound Guided Injection in Morton Neuroma
The aim of this work trial is to compare the effectiveness of blind and ultrasound guided injection for Morton neuroma in order to determine which is more appropriate as the initial procedure in conservative treatment
- Trial name
- NCT03046108
- Testing
- blind injection of Morton neuroma, blind injection of Mepivacaine, blind injection of Triamcinolone
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Complejo Hospitalario Universitario de Granada
Symptomatic Neuroma, Morton's Neuroma
Study of AxoGuard® Nerve Cap and Neurectomy for Treatment of Symptomatic Neuroma & Prevention of Recurrent Neuroma Pain
Comparing safety, pain, user experience, healthcare economic costs, work productivity, impairment and quality of life outcomes between Axoguard® Nerve Cap and neurectomy in the treatment of symptomatic neuromas in the foot or…
- Conditions
- Symptomatic Neuroma, Morton's Neuroma, Chronic Nerve Pain
- Trial name
- REPOSE (NCT03940963)
- Testing
- AxoGuard® Nerve Cap, Standard Neurectomy
- Where
- 11 sites in United States
- Volunteers
- 86 people
- Sponsor
- Axogen Corporation