Clinical trials: Motor Dysfunction
Aging, Elderly
Successful Aging and Age-related Decline
Recent studies have shown promising cognitive and physical interventions aimed at slowing down ageing-related declines in quality of life, but they lack strong ecological validity (brief durations, unrealistic goals, no…
- Conditions
- Aging, Elderly, Cognitive Decline, Physical Decline
- Trial name
- MyAgeWell (NCT06376656)
- Testing
- Cognitive stimulation, Physical activity
- Where
- Malaysia
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Sunway University
Parkinson Disease, Motor Disorders
Motor-cognitive Dual-task in Healthy Older Adults and Early Parkinson's Disease Patients
Neuromuscular dysfunction is common in older adults and even more pronounced in neurodegenerative diseases. In Parkinson's disease (PD), a complex set of factors often prevents effective performance of activities of daily living…
- Conditions
- Parkinson Disease, Motor Disorders, Cognitive Impairment
- Trial name
- TwinBrainPD (NCT05477654)
- Testing
- Extensive motor-cognitive testing protocol
- Where
- Slovenia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Science and Research Centre Koper
Subjective Cognitive Impairment, Mild Cognitive Impairment
Molecular Mediators of Physical Exercise and Carnosine Induced Effects in Patients With Preclinical and Early Stage Neurodegenerative Disease
The purpose of this study is to investigate the beneficial effects of regular exercise and the impact of food supplement carnosine on cognitive, motoric and metabolic functions as well as on specific biologically active…
- Conditions
- Subjective Cognitive Impairment, Mild Cognitive Impairment, Parkinson Disease, Healthy Volunteers
- Trial name
- NCT03330470
- Testing
- exercise, carnosine supplementation, stretching
- Where
- 3 sites in Slovakia, Taiwan
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Slovak Academy of Sciences
Physical Activity, Functional Disturbance
Effects of Dextrose on Knee Osteoarthritis
Using double blind, randomized controlled design to study the immediate, short-term and intermediate-term therapeutic effects of ultrasound guided hyaluronic acid injection and hyaluronic acid combined dextrose injection to…
- Trial name
- NCT03238183
- Testing
- dextrose, hyaluronic acid
- Where
- Taiwan
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Growth Failure, Atopy
The PREWEAN Study. Weaning of Preterm Infants During the First Year of Life.
In this Austrian observational study preterm infants born with a birth weight <1500 g and a gestational age <32 weeks will be investigated at the neonatal outpatient clinic.
- Conditions
- Growth Failure, Atopy, Adiposity, Cognitive Impairment
- Trial name
- PREWEAN (NCT02936219)
- Where
- Austria
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Women Health, Physiotherapy
Pelvic Floor Physiotherapy Combined With Sexual Therapy in Vaginismus Treatment
Studies on pelvic floor physiotherapy in individuals diagnosed with vaginismus are quite limited in the literature. While current studies have focused on certain physiotherapy modalities, the literature is quite limited in terms…
- Conditions
- Women Health, Physiotherapy, Exercise
- Trial name
- NCT06760767
- Testing
- sexual therapy, Pelvic floor physiotherapy combined with sexual therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Medipol University
Vestibular Diseases
2BALANCE: Cognitive-motor Dual-tasking in Persons with Vestibular Disorders
The overall aim of this study is to elucidate the impact of a vestibular dysfunction on the cognitive and motor performance by means of an extensive test protocol, evaluating the vestibular, cognitive and motor function using…
- Trial name
- NCT04126798
- Testing
- Behavioural
- Where
- Belgium
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Memory Deficits, Aging
The Effect of Tai Chi and Therapy by Dance and Movement on Blood Irisin Levels in Older Adults Over 65 Years of Age.
The aim of this project is to estimate the effects of therapy with dance and movement and Tai Chi on irisin plasma levels, a myokine with proven neuroprotective effects, in the context of baseline levels of cognitive function and…
- Conditions
- Memory Deficits, Aging, Cognitive Impairment, Physical Activity
- Trial name
- NCT05363228
- Testing
- Therapy by Dance and Movement, Tai Chi
- Where
- 2 sites in Czechia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
Stroke, Stroke with Hemiparesis
Study of Hemodynamic Markers of Upper Extremity Motor Dysfunction in Stroke Patients Using Functional Near Infrared Spectroscopy (fNIRS)
The aim of the study was to explore potential pathways for recovery and adaptation of the motor cortex by examining cerebral blood flow characteristics and hemodynamic markers analyzed by functional near-infrared spectroscopy…
- Conditions
- Stroke, Stroke with Hemiparesis, Stroke, Ischemic
- Trial name
- NCT06806397
- Testing
- Stimulus response task
- Where
- 2 sites in Russia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Skolkovo Institute of Science and Technology
Mild Cognitive Impairment
WAVE: AudioVisual Stimulation Enhances Cognitive, Mental and Physical Health in Elderly
The goal of this randomized controlled trial is to 1) carry out a screening of cognitive function, depressive symptoms, agility and functional balance and chronic inflammatory conditions in older adults; 2) analyze the influence…
- Trial name
- NCT06686563
- Testing
- Intervention Group: Gamma stimulation, Control Group: Theta stimulation
- Where
- Portugal
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Maria Paço
Memory Disorders, Mild Cognitive Impairment
Physical Exercise for Prevention of Dementia
The principal aim of this study is to verify whether a program of supervised, multimodal physical exercise improves cognitive function and/or reduces the rate of cognitive decline in older adults
- Conditions
- Memory Disorders, Mild Cognitive Impairment, Aging
- Trial name
- EPD (NCT02236416)
- Testing
- Intervention group, Control group
- Where
- Italy
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Molise
Acute Ischemic Stroke
The Effect and Mechanism of wCST-LL Based Precision Rehabilitation Nursing on Motor Dysfunction After Acute Stroke
Ischemic stroke is the main cause of disability in the world. More than 70% of stroke patients show various degrees of neural function impairment.
- Trial name
- NCT03702452
- Testing
- functional rehabilitation nursing program, control group
- Where
- China
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Neurologic Deficits, Neurologic Disorder
NeuroSeq: A Prospective Trial to Evaluate the Diagnostic Yield of Whole Genome Sequencing (WGS) in Adult Neurology
Prospective, multi-site, single-arm study to evaluate the diagnostic yield of cWGS in adults with neurological disorders. A single cohort naive of genetic testing will receive standard of care testing for 180 days followed by…
- Conditions
- Neurologic Deficits, Neurologic Disorder, Neurologic Abnormalities
- Trial name
- NeuroSEQ (NCT04170985)
- Testing
- clinical Whole Genome Sequencing
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Illumina, Inc.