Clinical trials: Motor Function
Metabolic Syndrome, Obesity
Three Lifestyle Interventions on Endothelial Function and Cardiometabolic Risk in Obese Patients With Metabolic Syndrome
Obese patients with metabolic syndrome without diabetes or ischemic heart disease were randomized to three lifestyle interventions: 1. hypocaloric tailored diet with standard recommendations 2.
- Trial name
- NCT00943865
- Testing
- hypocaloric diet, Exercise recommendations, Pragmatic diet
- Where
- Brazil
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Obesity
Effect of Weight Loss and Exercise on Liver and Muscle Fat in Obese Elderly
The purpose of this study is to determine the effect of weight loss and exercise on liver and muscle fat.
- Trial name
- NCT00779207
- Testing
- weight loss and exercise, weight loss
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
People With Impaired Motor Function in the Cervical Region
Cervical Functionality and Posture (CERFUPOS)
BACKGROUND: Musculoskeletal alterations of the cervical region constitute clinical situations with a high prevalence that may be related to posture mismatches.
- Trial name
- CERFUPOS (NCT04299672)
- Testing
- Postural reconstruction
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidad Antonio de Nebrija
Cognitive Function, Physical Activity
Change Physical Activity and School Play Space. Randomized Study Protocol.
Physical activity is a factor that contributes to a motor and cognitive development in early childhood. Currently, childhood obesity has grown steadily in Chile.
- Conditions
- Cognitive Function, Physical Activity, Children, Behavior, Child
- Trial name
- Play&Cognition (NCT05020041)
- Testing
- Physical activity
- Where
- Chile
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Universidad Autónoma de Chile
Cerebral Palsy, Typically Developing Children
Repetitive Transcranial Magnetic Stimulation on Motor Function and Meta-Plasticity in Cerebral Palsy: TMS-EEG Study
This project examines the use of repetitive transcranial magnetic stimulation (rTMS) as a therapeutic approach to improve motor function in children with cerebral palsy (CP).
- Trial name
- NCT07567053
- Testing
- MRI, HD-EEG Recording, rTMS
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cook Children's Health Care System
Developmental Dyslexia, Developmental Coordination Disorder
Functional MRI Study in Children With a Developmental Coordination Disorder (DCD) and/or Developmental Dyslexia (DD)
All the studies underlined the high frequency of co-morbid associations in specific learning disorders. Understanding the reasons for these associations could enable us to determine the cerebral bases that underlie each disorder.
- Trial name
- FMRI-DCD-DD (NCT02393729)
- Testing
- Neuropsychological assessment, MRI Study
- Where
- France
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Obesity, Insulin Resistance
Effects of Exercise Training Intensity on Fitness and Insulin Sensitivity in African Americans
African Americans are at a substantially greater type 2 diabetes risk compared to Caucasians; however, very little data are available on the effects of exercise training on type 2 diabetes risk factors in at risk African…
- Conditions
- Obesity, Insulin Resistance, Sedentary Lifestyle
- Trial name
- HI-PACE (NCT02892331)
- Testing
- Moderate intensity exercise training (MOD-INT), High Intensity exercise training (HI-INT)
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- East Carolina University
Exercise Performance, Cognitive Function
The Effects of a Novel Mitochondrial Substrate Supplement on Exercise Performance and Cognitive Function
The goal of this clinical trial is to compare the effects of taking a new supplement for 16 days on cognitive function and exercise performance, compared to a placebo (a supplement that looks and tastes the same, but doesn't have…
- Trial name
- MCh1 (NCT06374641)
- Testing
- Mitochondrial Substrate Supplement
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Healthy
Non-erythroid Effects of Erythropoietin on Cognitive Function and Exercise Capacity in Humans
The blood hormone Erythropoietin (Epo) is not only produced by the kidneys but also by the brain, especially under hypoxic conditions. It has been shown in animal studies and human studies that Epo has neuroprotective properties.
- Trial name
- NCT01889056
- Testing
- Erythropoietin (Epoetin beta)
- Where
- Switzerland
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Parkinson's Disease, Multiple Sclerosis
Blood Lactate Concentrations With and Without Exercise in Parkinson's Disease and Multiple Sclerosis Patients
Fatigue is one of the most common and debilitating symptoms experienced in Parkinson's Disease (PD) and Multiple Sclerosis (MS).
- Trial name
- PDMSLac (NCT02184494)
- Testing
- pro5 AIRdaptive Power Plate (Badhoevedorp, The Netherlands)
- Where
- 2 sites in United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Florida State University
Cognitive Ability, General
Neuropsychological Effects of Strengthening Exercise for Older Adults
This study aims to examine the benefits to thinking processes of a low intensity, strengthening exercise program for older adults.
- Trial name
- NCT00894205
- Testing
- strengthening exercise program
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Union College, New York
COPD, Tetrahydrobiopterin Deficiency
O2 Transport and Utilization in Health and Lung Disease
Skeletal muscle dysfunction is a frequent and clinically relevant systemic manifestation of Chronic Pulmonary Obstructive Disease (COPD), which is still poorly understood.
- Conditions
- COPD, Tetrahydrobiopterin Deficiency, Oxidative Stress
- Trial name
- NCT04014712
- Testing
- Tetrahydrobiopterin
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Massachusetts, Amherst
Sarcopenia, Aging
Dual-benefits of Aerobic and Resistance Training
This study evaluates the effect of three different exercise strategies on physical function in older adults. Participants will be randomly assigned to one of three exercise groups: resistance training, moderate-intensity…
- Conditions
- Sarcopenia, Aging, Disability Physical
- Trial name
- DART (NCT03978572)
- Testing
- Resistance Training, Moderate-Intensity Continuous Cycling, High-Intensity Interval Cycling
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ohio University
Creativity, Executive Function (Cognition)
Active Breaks and Executive Function in Scholars
This study aims to examine whether short bouts of exercise (10 minutes) performed during the school day can improve thinking skills, creativity and emotional wellbeing in primary school children.
- Conditions
- Creativity, Executive Function (Cognition), Psychological Wellbeing
- Trial name
- ACTISTOP (NCT07538453)
- Testing
- Active Break
- Where
- Spain
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Universitat Jaume I
Physical Activity, Blood Pressure
Multilevel Intervention for Physical Activity in Retirement Communities
The purpose of this study was to assess whether a 6-month multilevel physical activity intervention can significantly increase physical activity levels in sedentary adults, 65 and older, living in Continuing Care Retirement…
- Conditions
- Physical Activity, Blood Pressure, Physical Functioning, Quality of Life
- Trial name
- MIPARC (NCT01155011)
- Testing
- Physical Activity, Group educational sessions, Phone counseling call
- Where
- United States
- Volunteers
- 307 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Mental Health, Multiple Sclerosis
Upper Limb Function in Mental Health Disorders
Background: Individuals with mental disorders (MD) often experience motor issues, yet upper limb functionality remains understudied.
- Trial name
- UFMC-MH2025 (NCT06949449)
- Where
- Spain
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Universidad de Burgos
Real Neurofeedback From DMN, Sham Neurofeedback From Motor Cortex
Neurofeedback in Clinical High Risk
The goal of this trial is to test whether fMRI based neurofeedback from default mode network (DMN) will reduce DMN hyperconnectivity in clinical high risk individuals, which will lead to reductions in clinical symptoms and…
- Trial name
- NCT06492343
- Testing
- fMRI based neurofeedback
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Boston VA Research Institute, Inc.
Worksite Health Promotion, Lifestyle Risk Reduction
Intervention to Increase Physical Activity and Wellbeing Among Staff and Residents in Assisted Living Facilities
The purpose of the study is to test a program that aims to help staff increase wellness behaviors and test the impact of this program on staff and work outcomes.
- Conditions
- Worksite Health Promotion, Lifestyle Risk Reduction, Occupational Burnout, Healthcare Workers
- Trial name
- WHHIP+FFC 2026 (NCT07785947)
- Testing
- WHHIP, FFC
- Where
- United States
- Volunteers
- 344 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Athletes, Sports Performance
Neuro-Psychophysiological Characteristics of Athletes With Varying Levels of Experience
This study aims to investigate the effects of an 8-week volleyball-specific stroboscopic training program on neuro-psychophysiological outcomes in female volleyball players with different levels of competitive experience.
- Conditions
- Athletes, Sports Performance, Visual-Motor Processing, Neuro-Psychophysiological Responses in Athletes
- Trial name
- NEPSY-SPORT (NCT07392385)
- Testing
- Stroboscopic Volleyball Training, Conventional Volleyball Training (Control)
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Bozok University
Exercise, Square Step Exercises
Square Step Exercises in Healthy Young Adults
This study aims to compare the effectiveness of Square Stepping Exercise and aerobic exercise on cognitive function and physical fitness in young adults.
- Conditions
- Exercise, Square Step Exercises, Aerobic Exercise, Cognitive Function
- Trial name
- NCT06331078
- Testing
- Square Stepping Exercise training, Aerobic Exercise Training
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Fenerbahce University
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