Clinical trials: Motor Recovery
Cerebrovascular Accident, Hemiplegia
Post Stroke Hand Functions: Bilateral Movements and Electrical Stimulation Treatments
The purpose of this study was to determine the effect of two amounts of treatment therapy on post stroke motor recovery in the arms.
- Trial name
- NCT00369668
- Testing
- Bilateral movements and neuromuscular electrical stimulation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Florida
Stroke
How do Psychosocial Factors Relate to Completing a Home Exercise Program for Arm and Hand Recovery in Veteran Stroke Survivors?
Research shows that exercising at home can improve arm and hand movement after a stroke. Unfortunately, it can be hard to exercise enough to make a difference in arm and hand movement after stroke.
- Trial name
- VHE (NCT05616832)
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- VA Office of Research and Development
Stroke, Ischemic, Motor Activity
Transcranial Direct Current Stimulation for Post-stroke Motor Recovery
This research study is to find out if brain stimulation at different dosage level combined with an efficacy-proven rehabilitation therapy can improve arm function.
- Conditions
- Stroke, Ischemic, Motor Activity, Upper Extremity Paralysis
- Trial name
- TRANSPORT 2 (NCT03826030)
- Testing
- Low dose tDCS, High dose tDCS, mCIMT
- Where
- 14 sites in United States
- Volunteers
- 129 people
- Sponsor
- Duke University
Cerebrovascular Disease; Sequelae
Machines Assisting Recovery From Stroke
Locomotor disability remains a major obstacle to community function in stroke survivors. This disability is best characterized by the reduced gait speed and enhanced risk of falls that is observed in the majority of stroke…
- Trial name
- MARS (NCT02787694)
- Testing
- Factor Targeted Walking Training, treadmill
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Alabama at Birmingham
Aortic Valve Stenosis
Home-Based Exercise Program For Recovery After Transcatheter Aortic Valve Replacement
Transcatheter aortic valve replacement (TAVR) is a minimally invasive procedure for older adults with severe symptomatic aortic stenosis who are considered high risk for surgical aortic valve replacement.
- Trial name
- REHAB-TAVR (NCT02805309)
- Testing
- Exercise, Cognitive behavioral interventions, Attention control education program
- Where
- 3 sites in United States
- Volunteers
- 64 people
- Sponsor
- Brigham and Women's Hospital
Stroke, Hemiparesis
Translating Intensive Arm Rehabilitation in Stroke to a Telerehabilitation Format
Loss of arm use and strength are common problems after stroke that greatly affects independence in activities of daily living. Arm rehabilitation using robot-assisted repetitive task training has shown to improve motor recovery.
- Trial name
- TeleBATRAC (NCT02665052)
- Testing
- Home-Based BATRAC plus TTT, Lab-based BATRAC plus TTT, Delayed Entry Usual Care
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- VA Office of Research and Development
Stroke
Ipsihand Device Use in Stroke Patients to Assess Functional Motor Outcomes
This study aims to evaluate the impact of the Neurolutions Upper Extremity Rehabilitation System, known as IpsiHand, on improving functional motor control for post-stroke patients with hemiparesis.
- Trial name
- NCT04338971
- Testing
- IpsiHand Therapy
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- Neurolutions, Inc.
Stroke, Cerebrovascular Accident
Enhancing Plasticity in Stroke Patients With Severe Motor Deficit
This study will evaluate the effectiveness of sustained peripheral nerve stimulation coupled with functional motor training, to improve hand motor function in poorly recovered stroke patients.
- Trial name
- NCT02633215
- Testing
- S88 Dual Output Stimulator by Grass Technologies
- Volunteers
- 36 people
- Sponsor
- Lumy Sawaki
Stroke, Cerebrovascular Accident
Combining Armodafinil With Neuro-rehabilitation to Improve Neurological Recovery and Reduce Disability Post-Stroke
Armodafinil is an FDA approved medication with wakefulness-promoting properties. It is a relatively safe agent with interesting neurochemical effects on the catecholamine system, producing an improvement in cognitive function…
- Conditions
- Stroke, Cerebrovascular Accident, Hemiparesis
- Trial name
- NCT01896128
- Testing
- Armodafinil
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Burke Rehabilitation Hospital
Stroke
Effects of Device-assisted Practice of ADL on Arm/Hand Recovery in Individuals With Moderate to Severe Stroke
A large number of post-stroke survivors cannot functionally use their paretic upper extremity (UE). This study therefore investigates effects of device-assisted practice of activities of daily living (ADL) in a close-to-normal…
- Trial name
- NCT04077073
- Testing
- ReIn-Hand, Robot
- Where
- 2 sites in United States
- Volunteers
- 53 people
- Sponsor
- Northwestern University
Stroke, Sensorimotor Impairment
Learning in Stroke
After a stroke, plasticity occurs in the brain from microscopic to network level with positive but also negative consequences for functional recovery.
- Trial name
- NCT05511467
- Testing
- Visuomotor learning task
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Parkinson's Disease, Drug-induced Parkinsonism
Effect of Exercise in Parkinsonism
Parkinson's disease (PD) is a common neurodegenerative disorder affecting approximately 80,000 Veterans, representing a priority area for VA research.
- Trial name
- NCT02598973
- Testing
- Exercise
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- VA Office of Research and Development
Stroke, Motor Function
Effects rTMS Combined With Fluoxetine on Motor Recovery in Stroke Patients
In this study investigator's aim to assess the effect of a type of non-invasive brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) in conjunction with fluoxetine on motor recovery after stroke.
- Trial name
- NCT02208466
- Testing
- Active Repetitive Transcranial Magnetic Stimulation (rTMS), Fluoxetine
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Spaulding Rehabilitation Hospital
Stroke, Hemiparesis
Electrical Stimulation for Recovery of Ankle Dorsiflexion in Chronic Stroke Survivors
Ankle dorsiflexor weakness (paresis) is one of the most frequently persisting consequences of stroke. The purpose of this exploratory study is to compare two different treatments -- Contralaterally Controlled Neuromuscular…
- Conditions
- Stroke, Hemiparesis, Lower Extremity Paresis
- Trial name
- NCT01029912
- Testing
- Electrical stimulator
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- MetroHealth Medical Center
Atomoxetine Hydrochloride, Placebos
Post-stroke Neural Plasticity With Atomoxetine
This proposal evaluates the safety and effectiveness of a noradrenergic drug named atomoxetine combined with motor training to enhance cortical plasticity and improve hand function after stroke.
- Trial name
- NCT02788357
- Testing
- Atomoxetine
- Volunteers
- 12 people
- Sponsor
- Lumy Sawaki
Whiplash Associated Disorders (WAD), Whiplash
Neuromuscular Mechanisms Underlying Poor Recovery From Whiplash Injuries
This study is investigating whether changes in the shape and size of bodily muscles and spinal cord anatomy can influence recovery rates following a motor vehicle collision (MVC).
- Trial name
- NCT02157038
- Testing
- Pedometer, MRI
- Where
- United States
- Volunteers
- 97 people
- Sponsor
- Northwestern University
Stroke
Improving Rehabilitation by Magnetic Brain Stimulation
We hope to understand the properties of the motor cortex in the brain of people with stroke using non-invasive magnetic stimulation.
- Trial name
- NCT00636701
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Stroke
Robots Paired With tDCS in Stroke Recovery
The purpose of this study is to evaluate if multiple therapy sessions of Transcranial Direct Current Stimulation (tDCS non-invasive brain stimulation) combined with robotic arm therapy lead to a greater functional recovery in…
- Trial name
- NCT01726673
- Testing
- Transcranial Direct Current Stimulation (tDCS)
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Northwell Health
Stroke, Cerebrovascular Accident
Driving Neuroplasticity With Nerve Stimulation and Modified CIT
The investigators proposed to evaluate the effectiveness of sustained peripheral nerve stimulation (PNS) to enhance the therapeutic effects of a modified form CIT (mCIT).
- Trial name
- NCT02587234
- Testing
- peripheral nerve stimulation
- Volunteers
- 21 people
- Sponsor
- University of Kentucky
Cerebrovascular Accident
Mechanisms of Upper-Extremity Motor Recovery in Post-stroke Hemiparesis
The results of this study will provide sound, scientific evidence of physiologic mechanisms responsible for upper-extremity weakness; evidence of the processes involved in neuromuscular adaptation; and will elucidate the…
- Trial name
- NCT00125658
- Testing
- Control, Experimental
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development