Clinical trials: Motor Recovery
Erbs Palsy
Electrical Stimulation on Erbs Palsy Infants
This study examined the effect of reciprocal electrical stimulation (RES) across elbow flexors and extensors on the reaction of degeneration percentage and motor function in Erbs palsy infants.
- Trial name
- RES (NCT06631664)
- Testing
- Traditional physical therapy, A computerized electrical stimulator (Vectra®2C; Chattanooga, TS, USA)
- Where
- Saudi Arabia
- Volunteers
- 40 people
- Sponsor
- Badr University
Ischemic Stroke, Upper Extremity Weakness
Memantine for Enhanced Stroke Recovery
This will be a randomized double blind placebo-controlled pilot study using a repeated measures design in which participants with acute ischemic stroke and upper extremity weakness are randomized to either drug or placebo
- Trial name
- NCT02144584
- Testing
- Memantine XR
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Utah
Stroke, Hemiplegia
The Efficacy & Safety of rTMS for Upper-limb Motor Function Recovery in Subcortical and Brainstem Stroke
The purpose of this study is to evaluate the efficacy and safety of repetitive transcranial magnetic stimulation applied with an electromagnetic therapy stimulator 'ALTMS-A' for upper-limb motor function recovery with the sham…
- Conditions
- Stroke, Hemiplegia, Subcortical Infarction
- Trial name
- NCT05535504
- Testing
- Low-frequency rTMS (experimental)
- Where
- 2 sites in South Korea
- Volunteers
- 60 people
- Sponsor
- Seoul National University Bundang Hospital
Stroke, Sensorimotor Impairment
Learning in Stroke
After a stroke, plasticity occurs in the brain from microscopic to network level with positive but also negative consequences for functional recovery.
- Trial name
- NCT05511467
- Testing
- Visuomotor learning task
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Cardiac Surgery, Enhanced Recovery
Preventing Cardiac Surgery Readmission With Patient Activity Tracking Technology
The aim of this study is to detect decreased patient activity level after discharge after cardiac surgery to prevent readmissions.
- Trial name
- NCT04348981
- Testing
- Wearable fitness tracking device
- Sponsor
- Brigham and Women's Hospital
Stroke
Clinical Features and Rehabilitation Effect in Patients With Stroke
Dosage of rehabilitation therapy is a key factor in promoting motor functional recovery after stroke. To date, what is not yet known are the clinical features (e.g.
- Trial name
- PCR (NCT05478577)
- Testing
- Motor rehabilitation
- Where
- Italy
- Volunteers
- 35 people
- Sponsor
- IRCCS San Camillo, Venezia, Italy
Postpartum Pelvic Floor Dysfunction, Postpartum Urinary Incontinence
Exercise-Based Sensorimotor Physiotherapy for Postpartum Pelvic Health and Functional Recovery
This study evaluated whether a 12-week exercise-based sensorimotor physiotherapy program could improve pelvic health and functional recovery in postpartum women.
- Conditions
- Postpartum Pelvic Floor Dysfunction, Postpartum Urinary Incontinence, Postpartum Functional Recovery, Lumbopelvic Motor Control Impairment
- Trial name
- NCT07702565
- Testing
- Exercise-Based Sensorimotor Physiotherapy Program, Standard Postpartum Education and Home Advice
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Özge BAYKAN ÇOPUROĞLU
Obesity
Effects of High-intensity Exercise With Hypoxia and Taurine Supplementation on Metabolic and Mitochondrial Parameters
The prevalence of obesity in Brazil is one of the highest in Latin America. As an inflammatory disease, obesity needs to be treated, and one of the best interventions is exercise.
- Trial name
- NCT06579508
- Testing
- Cycle ergometer
- Where
- 2 sites in Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Neuropathic Pain Management
tACS for Neuropathic Pain Management After SCI
The overall goal is to investigate the effectiveness of a novel intervention - transcranial alternating current stimulation (tACS) for neuropathic pain management in people after spinal cord injury.
- Trial name
- NCT06029075
- Testing
- tACS 10Hz, tACS 20Hz
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- The University of Texas Health Science Center, Houston
Stroke
Effect of the Dose of Training in Upper Limb Motor Recovery After Stroke.
The aim of the study is to analyse the effect of intensive training on upper limb function in stroke patients. 20 stroke patients were randomly divided into two groups: the intensive group and the control group.
- Trial name
- NCT06571292
- Testing
- Intensive training with robotic exoskeleton for upper limbs, Task specific training
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Universidad de Zaragoza
Acute Stroke, Stroke Rehabilitation
Enhancement of Stroke Rehabilitation With Levodopa
Trial investigates the benefits and harms of Levodopa /Carbidopa 100/25mg compared to placebo (given in addition to standardized rehabilitation based on the principles of motor learning) and whether there is an association with a…
- Trial name
- ESTREL (NCT03735901)
- Testing
- IMP Levodopa 100mg/Carbidopa 25mg
- Where
- 24 sites in Switzerland
- Volunteers
- 610 people
- Sponsor
- University Hospital, Basel, Switzerland
Amputation
Enhancing Motor Function in Individuals with Lower Limb Amputation
The overall goal of this research project is to investigate the effectiveness and the science of peer-based prosthetic skill training in individuals with leg amputation.
- Trial name
- NCT06638723
- Testing
- Balance and fall recovery training
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Nevada, Las Vegas
Facial Palsy, Self-rehabilitation
Impacts of Two Rehabilitation Programs on Chronic Peripheral Facial Paresis
Introduction: Peripheral facial paresis (PFP) is a very common disease of various etiologies affecting average adults with no predominance of sex.
- Conditions
- Facial Palsy, Self-rehabilitation, Quality of Life, Motor Recovery
- Trial name
- VISAGE (NCT04074018)
- Testing
- Self-rehabilitation program, Conventional rehabilitation program
- Where
- 3 sites in France
- Volunteers
- 82 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Spinal Cord Injuries
rTMS and Body Weight-support Treadmill Training After Incomplete Spinal Cord Injury
The aim of this study is to verify the efficacy of body weight-support treadmill training combined with high-frequency rTMS in improving the sensory-motor function of adult patients with chronic incomplete thoracolumbar spinal…
- Trial name
- NCT03394560
- Testing
- High frequency repetitive transcranial magnetic stimulation
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Universidade Federal de Pernambuco
Adrenomyeloneuropathy Without Cerebral Involvement
Epidural Spinal Cord Stimulation for Lower-limb Impairment in Adrenomyeloneuropathy
Adrenal spinal neuropathy (AMN) is a rare X-linked genetic disease caused by mutations in the ABCD1 gene, and belongs to a special type of adrenal leukodystrophy.
- Trial name
- EPIC-AMN (NCT06796920)
- Testing
- Spinal cord stimulation
- Where
- 4 sites in China
- Volunteers
- 10 people
- Sponsor
- Third Military Medical University
Delirium - Postoperative, Agitation
Responsive Nature-Driven Imagery to Reduce Delirium After Cardiac Surgery
The goal of this clinical trial is to learn if a novel device (MindfulGarden) is beneficial in a population of patients undergoing cardiac surgery.
- Conditions
- Delirium - Postoperative, Agitation, Anxiety, Cardiac Surgery Recovery
- Trial name
- RESPITE (NCT07051096)
- Testing
- A novel device developed providing nature-driven responsive imagery that responds to the patient's physiological to distract, engage, and de-escalate behaviours of delirium., Routine post-operative management and standard delirium reduction measures.
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of British Columbia
Spinal Cord Injury, Tetraplegia/Tetraparesis
MEP Up-conditioning to Target Corticospinal Plasticity
Individuals with chronic cervical spinal cord injury will complete a 10-week training protocol where participants receive non-invasive brain stimulation and feedback on the size of the corresponding muscle response (wrist…
- Trial name
- uMEP2 (NCT06989905)
- Testing
- Up-conditioning of the wrist extensor motor evoked potential
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Medical University of South Carolina
Dementia, Cognitive Dysfunction ( MMSE < 24 )
Animal-Assisted Therapy Combined With Standard Rehabilitation for Motor Recovery in Dementia Patients in a Medical and Rehabilitation Care Unit
The goal of this randomized study is to find out if animal-assisted therapy (AAT) - a structured program where trained animals take part in care sessions guided by health professionals - can help improve movement abilities in…
- Conditions
- Dementia, Cognitive Dysfunction ( MMSE < 24 ), Motor Skills Disorders
- Trial name
- RéMédi - A (NCT07730983)
- Testing
- Animal-Assisted Therapy, Standard psychomotor rehabilitation
- Where
- France
- Volunteers
- 32 people
- Sponsor
- LNA SANTE
Mental Health Wellness
Two Recovery Strategies at Work, Based on Mindfulness and Physical Exercise, on Levels of Stress and Biological Measures
The present study aims to compare the differential effects of mindfulness meditation (MBI) and physical exercise (PE) on different stress and health variables (self-report means and IgA and cortisol levels).
- Trial name
- ERME2 (NCT05557266)
- Testing
- Mindfulness-based intervention, Physical exercise
- Where
- Spain
- Volunteers
- healthy volunteers welcome
- Sponsor
- Universidad Nacional de Educación a Distancia
Anesthesia, Spinal
Comparison of Clorotekal and Bupivacaine for Short Obstetric Surgery
The following obstetric procedures are commonly performed with spinal anesthesia on labor and delivery: bilateral tubal ligation, external cephalic version, cerclage insertion, cerclage removal, minimally invasive fetal surgery…
- Trial name
- CLIMB (NCT03967288)
- Testing
- Chloroprocaine Injection [Clorotekal], Bupivacaine Hydrochloride 0.75% Injection Solution
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University