Clinical trials: Motor Recovery
Transcranial Magnetic Stimulation
Theta Burst Stimulation for Motor Recovery
Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive neuromodulation technology. This study will compare efficacy of different doses iTBS in combination with inhibitory rTMS on motor recovery and cortical…
- Trial name
- NCT05613686
- Testing
- repetitive transcranial magnetic stimulation
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Muscular Injury
Almond Supplementation and Exercise Recovery
The PURPOSE of this study is to see if eating almonds for four weeks will reduce muscle damage, soreness, and inflammation during several days of recovery from eccentric exercise.
- Trial name
- NCT04958018
- Testing
- Almonds, Snack bars
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Appalachian State University
Stroke
Robots Paired With tDCS in Stroke Recovery
The purpose of this study is to evaluate if multiple therapy sessions of Transcranial Direct Current Stimulation (tDCS non-invasive brain stimulation) combined with robotic arm therapy lead to a greater functional recovery in…
- Trial name
- NCT01726673
- Testing
- Transcranial Direct Current Stimulation (tDCS)
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Northwell Health
Acute Stroke
Effect of tDCS Timing on Motor Recovery in Acute Stroke Rehabilitation
This randomized, double-blind, sham-controlled clinical trial investigates how the timing of transcranial direct current stimulation (tDCS) influences functional recovery during acute stroke rehabilitation.
- Trial name
- NCT07331779
- Testing
- tDCS
- Volunteers
- 60 people
- Sponsor
- University of Liege
Stroke
Effects of Using Advanced NEUROrehabilitation TECHnologies in Upper Limb Motor Function and Capacity Recovery in People With Stroke
This study aims to evaluate the effect of a personalized technology-based rehabilitative intervention on Upper Limb (UL) motor function and capacity recovery in People with Stroke (PwS).
- Trial name
- NEURO-TECH (NCT07698405)
- Testing
- Technology-based UL rehabilitation
- Where
- Italy
- Volunteers
- 25 people
- Sponsor
- Azienda Unita Sanitaria Locale di Piacenza
Stroke
Dose-Finding of Lower Limb Mirror Therapy After Stroke.
This study will investigate the maximum dose per day of using mirror therapy for ankle exercise after stroke. The design is a 3+3 rule based, dose- finding study. Each cohort will consist of three participants.
- Trial name
- NCT04339803
- Testing
- rehabilitation intervention
- Where
- United Kingdom
- Volunteers
- 19 people
- Sponsor
- University of East Anglia
Motor Neuropathy
Stroke Recovery Research Based on EEG-fMRI
This study is aimed to investigate the post-stroke motor recovery of patients with ischemic stroke based on their neural features extracted from EEG-fMRI data.
- Trial name
- EEG-fMRI (NCT05427422)
- Testing
- MRI recording, EEG recording
- Where
- China
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Xi'an Jiaotong University
Quality of Life, Physical Activity
The Effectiveness of an Online Exercise Program on Well-being of Postpartum Women
The aim of this quasi-experimental study was to assess the effectiveness of a 6-week online exercise program on self-assessed quality of life (QoL), physical activity (PA), and dysfunctions of pelvic floor muscles of postpartum…
- Conditions
- Quality of Life, Physical Activity, Urinary Incontinence, Pelvic Organ Prolapse
- Trial name
- NCT06268782
- Testing
- Rehabilitate your core
- Where
- Finland
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- University of Turku
Ictus, Severe Acquired Brain Injury
Personality Traits as a Variable in the Recovery of Patients With Acquired Brain Injury
This study aims to evaluate the potential effects of premorbid personality on the short- and long-term global cognitive recovery in patients with severe acquired brain injury (sABI) or stroke.
- Conditions
- Ictus, Severe Acquired Brain Injury, sABI
- Trial name
- NCT07119827
- Testing
- Motor, cognitive and psychological assessment
- Where
- Italy
- Volunteers
- 250 people
- Sponsor
- Universita di Verona
Schizophrenia
Aerobic Exercise for the Improvement of Cognition and Enhancement of Recovery in Post-acute Schizophrenia
The study investigates the efficacy of aerobic exercise on cognitive performance and brain plasticity in schizophrenia.
- Trial name
- NCT03466112
- Testing
- endurance training, balance and tone program
- Where
- Germany
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Ludwig-Maximilians - University of Munich
Stroke
Clinical Study to Investigate the Safety and Efficacy of MLC601 in 150 Iranian Patients After Stroke
To investigate the safety and efficacy of MLC601 (NeuroAideTM) as a Traditional Chinese Medicine on motor recovery after ischemic stroke.
- Trial name
- NCT01336153
- Testing
- MLC601
- Volunteers
- 150 people
- Sponsor
- Shahid Beheshti University
Cerebral Palsy (CP)
Structured Graphic Motor Therapy in Pediatric CP
Structured Graphic Motor Therapy (SGMT) is a novel task-oriented rehabilitation approach that uses standardized, progressively challenging drawing trajectories to improve upper-limb motor function in children with cerebral palsy.
- Trial name
- SGMT-CP (NCT07753083)
- Testing
- Structured Graphic Motor Therapy (SGMT), Conventional Upper-Limb Rehabilitation
- Where
- Armenia
- Volunteers
- 12 people
- Sponsor
- Armenian State Institute of Physical Culture and Sport
SARS-CoV Infection
Recovery of Exertion Ability Following COVID-19 Infection in Military Staff
The Paris Fire Brigade staff have been particularly exposed to COVID-19 due to rescue and care activities for victims at risk in Paris area (where the virus was actively circulating).
- Trial name
- CovEx (NCT04548505)
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Stroke
Transcranial Direct Current Stimulation and Robotic Therapy in Upper Limb Motor Recovery After Stroke
The objective of the study is to evaluate the effectiveness of transcranial direct current stimulation (tDCS) integrated with wrist robot-assisted treatment.
- Trial name
- NCT02496026
- Testing
- tDCS plus wrist robot therapy
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Auxilium Vitae Volterra
Stroke, Ischemic, Stroke Hemorrhagic
Multicenter Study on the Efficacy of Transcranial Direct Current Stimulation (tDCS) in Post-stroke Motor Recovery
Several previous studies have used tDCS as a neuromodulation tool, showing improvements in several diseases (Lefaucheur et al., 2017).
- Trial name
- NCT04166968
- Testing
- Anodal transcranial direct current stimulation (A-tDCS), Cathodal transcranial direct current stimulation (C-tDCS), Neuromotor training
- Where
- Italy
- Volunteers
- 162 people
- Sponsor
- IRCCS Centro San Giovanni di Dio Fatebenefratelli
Stroke, Ischemic, Motor Activity
Transcranial Direct Current Stimulation for Post-stroke Motor Recovery
This research study is to find out if brain stimulation at different dosage level combined with an efficacy-proven rehabilitation therapy can improve arm function.
- Conditions
- Stroke, Ischemic, Motor Activity, Upper Extremity Paralysis
- Trial name
- TRANSPORT 2 (NCT03826030)
- Testing
- Low dose tDCS, High dose tDCS, mCIMT
- Where
- 14 sites in United States
- Volunteers
- 129 people
- Sponsor
- Duke University
Stroke (Subacute)
Upper Extremity Orthoses Combined With Occupational Therapy in Subacute Stroke
This randomized controlled trial will investigate whether static or dynamic hand orthoses used as adjuncts to occupational therapy improve upper extremity recovery in adults with subacute stroke.
- Trial name
- NCT07864090
- Testing
- Standardized Occupational Therapy, Dynamic Hand Orthosis, Static Resting Hand Orthosis
- Where
- Greece
- Volunteers
- 102 people
- Sponsor
- University of Western Macedonia
Patients (>=60 Years Old) Suffering From Mild-moderate Stroke (Ischemic or Hemorrhagic, Stroke Severity Assessed by NIHSS <16 Points)
IMAGINE Study Protocol
Background: Rehabilitation pathways are crucial to reduce stroke-related disability. Motivational Interviewing (MI), a centred-person intervention aimed to empower and motivate the patient, could be a resource to improve…
- Trial name
- IMAGINE (NCT03434938)
- Testing
- Motivational interviewing
- Where
- 6 sites in Spain, Sweden
- Volunteers
- 272 people
- Sponsor
- Parc Sanitari Pere Virgili
Stroke, Stroke, Ischemic
MLC1501 Study Assessing Efficacy in Post STrOke Subjects With mOtor Deficits
This is a multi-center, randomized, double-blind, placebo-controlled trial of MLC1501 in patients with stroke. Eligible participants will be randomized in a 1:1:1 ratio to orally receive MLC1501 high-dose twice a day, MLC1501…
- Conditions
- Stroke, Stroke, Ischemic, Strokes Thrombotic, Stroke Sequelae
- Trial name
- MAESTOSO (NCT05289947)
- Testing
- MLC1501
- Where
- 11 sites in Philippines, Singapore
- Volunteers
- 303 people
- Sponsor
- Moleac Pte Ltd.
Stroke, Cerebrovascular Disorders
Dose Optimization for Stroke Evaluation
This study is about rehabilitation of arm function after a stroke. The investigators are testing the dosage of therapy that is needed for meaningful recovery of arm and hand function.
- Conditions
- Stroke, Cerebrovascular Disorders, Brain Ischemia, Infarction
- Trial name
- DOSE (NCT01749358)
- Testing
- Accelerated Skill Acquisition Program (ASAP), Active Monitoring
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Southern California