Clinical trials: Motor Recovery
Upper Extremity Paresis, Disability Physical
Hand Rehabilitation Study for Stroke Patients
The purpose of this study is to find out what are the best settings for applying electrical nerve stimulation over the skin for the short-term improvement of hand dysfunction after a stroke.
- Conditions
- Upper Extremity Paresis, Disability Physical, Chronic Stroke, Motor Disorders
- Trial name
- DOSES (NCT03148106)
- Testing
- Somatosensory Electrical Stimulation
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of California, San Francisco
Stroke, Stroke, Cardiovascular
EMG Control Assistance Virtual Reality Interface Coupled With Cerebellar-iTBS for Arm Recovery After Stroke (ERICA)
The investigators hypothesize that a myoelectric (EMG) controlled virtual reality (VR) interface allows for effective upper limb motor recovery of stroke patients.
- Trial name
- ERICA (NCT06911671)
- Testing
- Virtual Reality Interface + Cerebellar iTBS (c-iTBS), Physical Therapy
- Where
- Italy
- Volunteers
- 45 people
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia
Aortic Valve Stenosis
Home-Based Exercise Program For Recovery After Transcatheter Aortic Valve Replacement
Transcatheter aortic valve replacement (TAVR) is a minimally invasive procedure for older adults with severe symptomatic aortic stenosis who are considered high risk for surgical aortic valve replacement.
- Trial name
- REHAB-TAVR (NCT02805309)
- Testing
- Exercise, Cognitive behavioral interventions, Attention control education program
- Where
- 3 sites in United States
- Volunteers
- 64 people
- Sponsor
- Brigham and Women's Hospital
Sports Nutritional Sciences, Recovery
Whey Protein and Adaptogenic Supplementation in Physically Active Females
The goal of this clinical trial is to learn whether whey protein or plant protein supplements, with or without an adaptogenic herb blend, can improve strength, recovery, stress, and wellbeing in active females.
- Conditions
- Sports Nutritional Sciences, Recovery, Muscle Strength Recovery, Muscle Strength
- Trial name
- NCT07594444
- Testing
- Whey protein, Whey Protein With Adaptogenic Blend, Plant Protein Supplement
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sports Performance and Applied Research in Trials and Analysis
Low Back Pain, Orthopedic Disorder
Evaluation on the Effects of Two Rehabilitation Treatment and Tape for Functional and Motor Recovery of LBP Patients
The objective of this study is to verify which is the most effective type of rehabilitation treatment (rehabilitation based on core strengthening vs pilates) in patients suffering from low back pain.
- Conditions
- Low Back Pain, Orthopedic Disorder, Physical Therapy, Core Strengthening
- Trial name
- LBPT001 (NCT05419310)
- Testing
- Rehabilitation - core strengthening, Rehabilitation - rehabilitation pilates, Elastic taping application
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Campus Bio-Medico University
Cerebral Stroke
Can we Train Patients With Chronic Stroke Out of Abnormal Hand Synergy?
This study plans to determine whether training can change abnormal flexion synergy in chronic stroke patients.
- Trial name
- NCT03255590
- Testing
- Configuration task
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Johns Hopkins University
Stroke
Potential for Recovery of Voluntary Finger Extension After Stroke
Stroke patients with absent voluntary finger extension (VFE) 6-months after stroke are not expected to recover hand function. However, experience from the Queen Square Upper Limb neurorehabilitation service contradicts this view.
- Trial name
- PROVES (NCT07592247)
- Testing
- Neuromuscular Electrical Stimulation and Home Exercise Programme
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- University College, London
Stroke, Chronic Stroke
Psychedelic Healing: Adjunct Therapy Harnessing Opened Malleability
The main purpose of the current studies is to evaluate the safety and tolerability of psilocybin in patients with chronic stroke.
- Conditions
- Stroke, Chronic Stroke, Intracerebral Haemorrhage, Intracerebral Haemorrhage (ICH)
- Trial name
- PHATHOM (NCT07053917)
- Testing
- Psilocybin (Usona Institute)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Johns Hopkins University
Colorectal Surgery
Enhancing Outcomes After Colon Surgery
Most patients find that recovering from surgery is difficult particularly after abdominal surgery for cancer or other intestinal disorders.
- Trial name
- NCT00227526
- Testing
- Prehabilitation
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- McGill University
Stroke
Biopsychosocial and Motor Predictor of Functional Recovery in Stroke Survivors
Up to the researcher knowledge, there is currently limited literature available that thoroughly investigates the biopsychosocial and motor predictors of functional recovery in stroke survivors.
- Trial name
- NCT06140316
- Where
- Pakistan
- Volunteers
- 104 people
- Sponsor
- Riphah International University
Stroke
Non-Invasive Brain Signal Training to Induce Motor Control Recovery After Stroke
The purpose of this trial was to evaluate the benefits of combination motor learning training and brain computer interface training for restoring arm function in people with stroke.
- Trial name
- NCT00746525
- Testing
- Surface functional electrical stimulation (FES), Motor learning, Brain computer interface (BCI) training
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Louis Stokes VA Medical Center
Spinal Cord Injuries
BioFLO for Respiratory Recovery in SCI
Acute intermittent hypoxia (AIH) involves brief (1 min), repeated episodes (~15) of breathing low oxygen air to stimulate spinal neuroplasticity.
- Trial name
- NCT06011876
- Testing
- Acute Intermittent Hypoxia (AIH), Acute Intermittent Hypercapnic-Hypoxia (AIHH)
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- University of Florida
Glioma
Accelerating Motor Recovery in Glioma Patients Using Postoperative nrTMS
Project Name Clinical Research Protocol on Accelerating Motor Rehabilitation in Postoperative Motor-Deficient Glioma Patients Using nrTMS Research Objectives 1.
- Trial name
- NCT07285525
- Testing
- transcranial magnetic stimulation (TMS)
- Where
- China
- Volunteers
- 43 people
- Sponsor
- Beijing Neurosurgical Institute
Muscle Recovery
Investigating the Efficacy of Low or High Dose Tart Cherry on Recovery From Exercise Induced Muscle Damage and Establishing Its Molecular Mechanisms of Action
To determine the dose-response effects of 10-day tart cherry product consumption (0, 30 ml, and 60 ml) on knee extensor isometric strength 24-h and 48-h after muscle damaging exercise and to elucidate the mechanisms of action for…
- Trial name
- NCT04725149
- Testing
- 500 ml base solution, 500 ml containing 30 ml tart cherry concentrate diluted with water and base solution, 500 ml containing 60 ml tart cherry concentrate diluted with water only
- Where
- United Kingdom
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Stroke, Upper Extremity Dysfunction
Effects of Combined vs. Sequential Attentional Focus Instructions on Upper Extremity Function in Subacute Stroke
Stroke is a leading cause of long-term disability, and upper extremity impairments-affecting about 80% of survivors-limit functional reach, grasp, and manipulation more severely than lower limb deficits.
- Conditions
- Stroke, Upper Extremity Dysfunction, Cue, Threat
- Trial name
- NCT07289308
- Testing
- Combined Focus of Attention Instructions, Sequential Focus of Attention Instructions, standart rehabilitation program
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Bahçeşehir University
Stroke, Hemiplegia
Efficacy and Safety Study of rTMS for Upper Extremity Motor Function Recovery in Ischemic Stroke Patients
The purpose of this study is to Evaluate Efficacy and Safety of rTMS 『TMS』 for Upper Extremity Motor Function Recovery in Patients with Ischemic Stroke
- Trial name
- TAMAS (NCT02082015)
- Testing
- Low frequency rTMS
- Where
- 3 sites in South Korea
- Volunteers
- 77 people
- Sponsor
- Seoul National University Bundang Hospital
Stroke, Hemiparesis
Efficacy of Tele-CPASS Compared to In-person CPASS Therapy for Upper Extremity Motor Recovery
This study evaluates whether a home-based telerehabilitation program (tele-CPASS) is as effective as an in-person rehabilitation program (CPASS) for improving arm and hand function after stroke.
- Conditions
- Stroke, Hemiparesis, Upper Extremity Impairments, Stroke Rehabilitation
- Trial name
- NCT07661849
- Testing
- Tele-CPASS, In-person CPASS therapy
- Where
- 3 sites in United States
- Volunteers
- 42 people
- Sponsor
- University of Texas, El Paso
Cerebral Vascular Accident (CVA)/Stroke
The Natural History of Recovery After Stroke
The goal of this longitudinal observational study is to learn the course of recovery after stroke. Specifically, in this study we will learn and describe the changes in cognitive, motor and sensory function over time in stroke…
- Trial name
- RESTRO (NCT06441552)
- Testing
- non-interventional
- Where
- 3 sites in Israel, Palestinian Territories
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Adi Negev-Nahalat Eran
Stroke
AdaptRehab imVR: Exploring the Feasibility of imVR for Upper Limb Stroke Rehabilitation in Ethiopia
Stroke is a major cause of long-term disability worldwide, particularly in low- and middle-income countries (LMICs). Upper limb impairments following stroke can substantially limit an individual's ability to perform daily…
- Trial name
- imVR (NCT07412899)
- Testing
- Virtual Reality Headset with immersive exercises.
- Where
- Ethiopia
- Volunteers
- 18 people
- Sponsor
- Jimma University
Stroke
Upper Limb tDCS in Chronic Stroke Patients (NOURISH)
This study is a randomized double-blinded trial investigating the effect of Transcranial Direct Current stimulation (tDCS) on upper limb motor function rehabilitation in chronic stroke patients.
- Trial name
- NCT05608525
- Testing
- transcranial current stimulation, GRASP
- Where
- Singapore
- Volunteers
- 11 people
- Sponsor
- National University Hospital, Singapore