Clinical trials: Motor Recovery
Acute Stroke, Stroke, Ischemic
Measuring Ambulation, Motor, and Behavioral Outcomes With Post-Stroke Fluoxetine in Tanzania
This is a phase II, randomized study of 120 adults age 18 or above who will prescribed 20mg daily Fluoxetine for 90 days following acute, ischemic stroke.
- Trial name
- MAMBO (NCT03728153)
- Testing
- Fluoxetine 20 MG Oral Tablet
- Where
- Tanzania
- Volunteers
- 34 people
- Sponsor
- Massachusetts General Hospital
Acute Stroke
Focal Muscle Vibrations in Acute Stroke
A prospective, randomized, double-blind, sham-controlled trial designed to evaluate the effects of Repeated Muscle Vibration (rMV) on motor recovery in acute stroke patients treated within 72 hours of symptom onset
- Trial name
- VIBRAMAIN2 (NCT06793566)
- Testing
- Repeated Muscle Vibration (rMV)
- Where
- France
- Sponsor
- Centre Hospitalier Régional d'Orléans
Cerebrovascular Accident
Comparative Efficacy Research of Uni- vs Bi-lateral Arm Training Poststroke
This proposed project aims to compare the effects of dose-matched unilateral vs bilateral vs unilateral combined with bilateral upper limb rehabilitation based on task-related practice compare the effects of unilateral vs…
- Trial name
- NCT01525979
- Testing
- Task-related unilateral arm training, Task-related bilateral arm training, Robot-assisted bilateral arm training
- Where
- Taiwan
- Volunteers
- 42 people
- Sponsor
- Chang Gung Memorial Hospital
Brain Concussion
Examination of Balance, Vestibular, and Ocular Functions and Activity Following Concussion
Previous research and position statements have outlined the necessity of balance and gait testing in the post-concussion evaluation of athletes.
- Trial name
- NCT02317107
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Rehabilitation
Active MOBility Early After Stroke : What Should be the Best Physiotherapy Early After Stroke ?
This study is designed to observe the respective effects of 2 types of physiotherapy early after a cerebral stroke. The hypothesis is that an intensive physiotherapy early delivered (Day 2 to D15) after a stroke could induce…
- Trial name
- AMOBES (NCT01520636)
- Testing
- standard physiotherapy, experimental physiotherapy
- Where
- 2 sites in France
- Volunteers
- 104 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Stroke
Repetitive Nerve Stimulation to Improve Recovery After Stroke
Upper limb paresis is the most common type of post-stroke neurological impairment and a major cause of functional disability. Repetitive peripheral sensory stimulation (RPSS) is a novel strategy to improve upper limb motor…
- Trial name
- RESTORES (NCT03956407)
- Testing
- Suprathreshold repetitive peripheral sensory stimulation, Subthreshold repetitive sensory stimulation
- Where
- Brazil
- Volunteers
- 51 people
- Sponsor
- Hospital Israelita Albert Einstein
Brain Tumors, Transcranial Magnetic Stimulation
rTMS for Postoperative Brain Tumor Patients
When doctors perform surgery to remove brain tumors, the goal is to take out as much of the tumor as possible while keeping the patient's brain functions intact.
- Conditions
- Brain Tumors, Transcranial Magnetic Stimulation, Motor Deficit, Quality of Life
- Trial name
- NCT07530536
- Testing
- Transcranial magnetic stimulation (TMS)
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Brian J.Gill
Thoracic Surgery
Surgical Prehabilitation on Autonomic Nervous System (TUNE)
This study will be a multicenter interventional randomized trial evaluating the effect of a multimodal prehabilitation program on heart rate variability (HRV).
- Trial name
- TUNE (NCT06398301)
- Testing
- Multimodal prehabilitation Program
- Where
- 2 sites in Italy
- Volunteers
- 100 people
- Sponsor
- Università Vita-Salute San Raffaele
Cardiac Surgery, Enhanced Recovery
Preventing Cardiac Surgery Readmission With Patient Activity Tracking Technology
The aim of this study is to detect decreased patient activity level after discharge after cardiac surgery to prevent readmissions.
- Trial name
- NCT04348981
- Testing
- Wearable fitness tracking device
- Sponsor
- Brigham and Women's Hospital
Breast Cancer, Mobility Limitation
Breast: Recovery After Axillary Node Clearance - Evaluating Limbs With E-Technology (the BRACELET Study)
This work aims to use wearable sensors to record the return towards normal physical activity after breast surgery. It will build on current evidence by using objective measures of activity and arm movements rather than patient…
- Trial name
- BRACELET (NCT03635723)
- Testing
- Activity monitor
- Where
- United Kingdom
- Volunteers
- 75 people
- Sponsor
- Imperial College London
Spinal Anesthesia, Dexamethasone
Evaluating the Effect of Intravenous Dexamethasone on the Duration of Spinal Anesthesia After Cesarean Delivery
The goal of this clinical trial is to determine the effects of intravenous (IV) dexamethasone on spinal anesthesia in healthy women having an elective Cesarean delivery (CD) at the IWK Health Centre.
- Trial name
- NCT05731960
- Testing
- Dexamethasone, Metoclopramide
- Where
- Canada
- Volunteers
- 192 people
- Sponsor
- IWK Health Centre
Stroke
Psychometric Properties of Motor Recovery Assessment Scales for Stroke
Stroke is a common global health-care problem that is serious and disabling. In high-income countries, stroke is the third most common cause of death and is the main cause of acquired adult disability.
- Trial name
- NCT05973058
- Where
- Pakistan
- Volunteers
- 57 people
- Sponsor
- Riphah International University
Physical Activity, Bariatric Surgery
The Effect of Encouraging Patients Undergoing Obesity Surgery to Move on Physical Mobility, Recovery and Negative Effects of Surgery
Early mobilization and physical mobility have a critical role in minimizing complications after surgical procedures. Although there are a limited number of studies in the literature on the step count of bariatric surgery…
- Conditions
- Physical Activity, Bariatric Surgery, Quality of Recovery, Mobilization
- Trial name
- NCT07068828
- Testing
- Mobilization Encouragement Protocol, Smart Watch for Physical Activity Monitoring
- Volunteers
- 70 people
- Sponsor
- TC Erciyes University
Acute Stroke Intervention, Acute Stroke
Using AI Systems to Optimize the Clinical Outcome of Stroke Patients
This project addresses the imminent challenge of providing adequate motor rehabilitation to a growing number of stroke survivors amidst the ageing population, decreasing age of stroke, and shortage of physical/occupational…
- Conditions
- Acute Stroke Intervention, Acute Stroke, Acute Ischemic Stroke
- Trial name
- NCT06828679
- Testing
- Acupuncture, control group, Robotic Training
- Where
- Hong Kong
- Volunteers
- 400 people
- Sponsor
- Chinese University of Hong Kong
Peripheral Nerve Injury, Peripheral Nerve Discontinuity
Study Comparing Avance Nerve Graft and Autograft for Functional Recovery Following Mixed and Motor Peripheral Nerve Reconstruction
This is a multicenter, 1:1 randomized, prospective, comparative study in participants requiring reconstruction of a mixed or motor nerve in the upper extremity.
- Conditions
- Peripheral Nerve Injury, Peripheral Nerve Discontinuity, Mixed Peripheral Nerve Injury, Motor Peripheral Nerve Injury
- Trial name
- Nerve-RESTORE℠ (NCT07657182)
- Testing
- Avance Nerve Graft, Sural nerve autograft
- Where
- 3 sites in United States
- Volunteers
- 178 people
- Sponsor
- Axogen Corporation
Spinal Cord Injury
Spinal Cord Stimulation for Functional Recovery in Humans With Tetraplegia
In support of the long-term goal of developing new strategies to increase limb function after SCI, the objectives of this proposal are to: 1) Examine the behavioral and physiological effects of TESS on upper-limb muscles after…
- Trial name
- NCT05157282
- Testing
- TESS, Training, Motor Task
- Where
- 2 sites in United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Stroke
Brain-computer Interface With Plantar Pneumoorthoses for Post-stroke Rehabilitation
STUDY PURPOSE The investigators are testing a new rehabilitation system that helps stroke patients recover their ability to walk and think more clearly.
- Trial name
- BRAIN-WALK (NCT07081308)
- Testing
- NIRS-BCI-pneumoorthesis
- Where
- Russia
- Volunteers
- 30 people
- Sponsor
- Research Center of Neurology, Russia
Pediatric Brain Tumor, Cognitive Impairment
Fitness to Aid the Brain and Cognitive Skills
The study will assess the feasibility of a pilot clinical trial of community-led aerobic exercise training for paediatric brain tumour survivors (PBTS) and the feasibility of a web-based platform to deliver this exercise…
- Trial name
- Fit ABCS (NCT05367076)
- Testing
- Web-based Aerobic Exercise Program
- Where
- Canada
- Volunteers
- 26 people
- Sponsor
- The Hospital for Sick Children
Healthy
Dual Site-Dual Channel Non-invasive Brain Stimulation for Language and Cognitive Function in Healthy Subjects
The aim of this study is to investigate the effect of dual site-dual channel non-invasive brain stimulation for recovery of language and cognitive function in healthy.
- Trial name
- NCT03486808
- Testing
- IFG stimulation, DLPFC stimulation
- Where
- South Korea
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Stroke, Cerebrovascular Disorders
Cost-effectiveness of Forced Aerobic Exercise for Stroke Rehabilitation
The purpose of this study is to investigate whether aerobic exercise improves the participant's ability to recover function in the arm and leg affected by the participant's stroke.
- Conditions
- Stroke, Cerebrovascular Disorders, Brain Diseases, Central Nervous System Diseases
- Trial name
- NCT03819764
- Testing
- Aerobic Exercise, Upper Extremity Repetitive Task Practice
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- The Cleveland Clinic