Clinical trials: Motor Recovery
Fracture Femur, Hip Arthroplasty Replacement
Cognitive and Physical Recovery After Hip Fracture in Frail Patients Using Digital Rehabilitation Technology
The aim of this study is to evaluate whether integrating a technology-based rehabilitation approach with conventional therapies in the rehabilitation of patients with proximal femoral fracture may be advantageous compared with…
- Conditions
- Fracture Femur, Hip Arthroplasty Replacement, Total Hip Arthroplasty (THA)
- Trial name
- FEWF (NCT07392515)
- Testing
- Experimental intervention - integrated treatment with a sensor-based device, Conventional rehabilitation intervention
- Where
- 2 sites in Italy
- Volunteers
- 30 people
- Sponsor
- C.O.T. Cure Ortopediche Traumatologiche S.p.A.
Stroke, Upper Limb Paresis
Thermal Stimulation for Stroke Patients
Sensory and/or motor deficits in upper limb following stroke often have negative impacts on their daily living. Thermal stimulation with hot and cold pack alternatively incorporated into conventional rehabilitation has been…
- Trial name
- TSSP (NCT01658293)
- Testing
- thermal stimulation, control group ergometer exercises
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Buddhist Tzu Chi General Hospital
Anesthesia Outcomes, Anesthesia Complication
Does Style of Pre-sedation Instructions Improve Patient Outcomes in Ambulatory Anesthesia for Oral and Maxillofacial Surgery?
This randomized controlled trial aims to evaluate the impact of a brief guided visualization exercise on anesthesia-related outcomes in oral and maxillofacial surgery in patients scheduled for ambulatory anesthesia in the oral…
- Conditions
- Anesthesia Outcomes, Anesthesia Complication, Anesthesia and Procedure Related Time Intervals, Anesthesia Recovery Period
- Trial name
- NCT06768021
- Testing
- Guided visualization and standardized pre-sedation instructions, Standardized pre-sedation instructions only
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- Alameda Health System
Spinal Cord Injuries, Spinal Cord Injury at C5-C7 Level
Multi-functional Neuroprosthetic System for Restoration of Motor Function in Spinal Cord Injury
This study is to evaluate the use of a fully implanted device for providing hand function, reach, and trunk function to individuals with cervical spinal cord injury. Funding Sources: FDA OOPD NIH NINDS
- Conditions
- Spinal Cord Injuries, Spinal Cord Injury at C5-C7 Level, Spinal Cord Injury Cervical, Spinal Cord Injury at C5-C7 Level With Complete Lesion
- Trial name
- NNP-UE+T (NCT02329652)
- Testing
- Networked Neuroprosthetic System for Grasp and Trunk
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Anne Bryden
Stroke
Is Robot-Assisted Therapy Effective for the Upper Extremity Following a Stroke
The aim of this study was to investigate the effects on upper-limb motor function of the addition of robotic rehabilitation (RR) and conventional rehabilitation (CR) treatments to intensive trunk rehabilitation (ITR).
- Trial name
- NCT05559385
- Testing
- Robot-Assissted Therapy, Conventional Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 41 people
- Sponsor
- Emresenocak
Stroke
Motor rECovery witH eArly imagiNg In STroke
This study will contribute to the field of stroke rehabilitation research by expanding the investigator's understanding of the neural mechanisms responsible for the development and expression of abnormal flexion synergy, a…
- Trial name
- MECHANIST (NCT04165616)
- Where
- 3 sites in United States
- Volunteers
- 120 people
- Sponsor
- Northwestern University
Sports Nutritional Sciences, Sports Nutrition
Whey Protein and Adaptogenic Supplementation in Physically Active Males
The goal of this clinical trial is to learn whether whey protein, with or without an adaptogenic herb blend, can improve strength, recovery, stress, and wellbeing in active males.
- Conditions
- Sports Nutritional Sciences, Sports Nutrition, Recovery, Recovery Following Exercise
- Trial name
- NCT07716904
- Testing
- Whey protein, Dietary Supplement: Whey Protein With Adaptogenic Blend
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sports Performance and Applied Research in Trials and Analysis
Stroke, Hemiplegia
E-Rehabilitation: Aerobic Resistance Training for Stroke Survivors
This pilot study intends to evaluate an online exercise video rehabilitation program for stroke survivors with moderate disability compared to usual care.
- Trial name
- NCT02938000
- Testing
- Theraband with exercise video, usual care with advice to exercise
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Kaiser Permanente
Obstructive Sleep Apnea
The Influences of Intervention With Home-based Recovery Activity in Obstructive Sleep Apnea Syndrome
Background: OSAS is a type of sleep disorder characterized by intermittent, partial or complete upper airway (UA) collapse, seriously impacting sleep apnea and respiratory insufficiency.
- Trial name
- OSAS (NCT02278094)
- Testing
- Tongue Muscle Trainer (TMT), Threshold Inspiratory Muscle Trainer (TIMT), Walking Exercise
- Where
- Taiwan
- Volunteers
- 91 people
- Sponsor
- National Cheng-Kung University Hospital
Spinal Cord Injury, Spinal Cord Injury Subacute
Spinal Stimulation With Gait Training to Improve Lower Limbs Motor Recovery in Spinal Cord Injury
Spinal cord injury (SCI) often results in partial or complete loss of movement. In the subacute phase (< 6 months), the central nervous system shows increased potential for neuroplasticity, making it more responsive to…
- Conditions
- Spinal Cord Injury, Spinal Cord Injury Subacute, Locomotion, Gait Disorder, Sensorimotor
- Trial name
- CIMELocomotion (NCT07375745)
- Testing
- Protocol 2: Gait training combined with an effective tSCS
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Centre for Interdisciplinary Research in Rehabilitation of Greater Montreal
Stroke, Ischemic
Network Properties As Biomarkers for Non-Invasive Brain Stimulation (NIBS) After Stroke
The present study will evaluate the potential of cortico-cerebellar network properties derived from neuroimaging in a group of chronic stroke patients to explain inter-subject variability in responsiveness to transcranial direct…
- Trial name
- MARK-NIBS (NCT05560724)
- Testing
- Transcranial direct current stimulation (tDCS)
- Where
- Germany
- Volunteers
- 81 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Stroke
Effectiveness of Neuromuscular Electrical Stimulation After Stroke
A Randomized Clinical Trial (RCT) was conducted to determine the effects of two neuromuscular electrical stimulation protocols with different stimulation frequencies on motor recovery in older adults with spastic hemiparesis…
- Trial name
- NCT03913624
- Testing
- Neuromuscular electrical stimulation
- Where
- Spain
- Volunteers
- 69 people
- Sponsor
- University of Valencia
Rett Syndrome
Technology-supported Motor Rehabilitation for People With Rett Syndrome
This study focuses on improving purposeful arm use while simultaneously reducing engagement in stereotypies. It is typically expected that the training period for this study will last about 6 months.
- Trial name
- TeMoRett (NCT07418905)
- Testing
- computer gaming
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Georgetown University
Drop Foot
Does Blood Vessel Vasodilation, Caused by Focal Infiltration of Lidocaine Cause Temporary Nerve Functional Recovery for Patients with Common Peroneal Nerve Injury or Entrapment: Testing the 'Phoenix Sign' Effect Between Lidocaine (a Common Local Anesthetic) and Papaverine, a Know Vasodilator
The goal of this clinical trial is to compare lidocaine without epinephrine to papaverine a known vasodilatory agent, in creating improved motor strength in patients with drop foot involving an entrapment of the Common Peroneal…
- Trial name
- NCT06637046
- Testing
- Diagnostic procedures, Lidocaine HCl
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Stephen Barrett
Stroke
ROBOtic Care of Post-stroke Pain.
In agreement to the Initiative on Methods, Measurement, and Pain Assessment in Clinical Trials (IMMPACT) recommendations that support the importance of physical functioning as core outcome for pain this randomized, double-blind…
- Trial name
- Robocop (NCT05288270)
- Testing
- Aramis, Conventional therapy
- Volunteers
- 118 people
- Sponsor
- S.Anna Rehabilitation Institute
Brain Infarction, Brain Ischemia
Transcranial Direct Current Stimulation, Improve Functional Motor Recovery, Affected Arm
Overall goal of this study is to determine if transcranial direct current stimulation (tDCS) plus conventional occupational therapy improves functional motor recovery in the affected arm-hand in patients after an acute ischemic…
- Trial name
- NCT01201629
- Testing
- t DC stimulation, tDCStimulation
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Oklahoma
Cancer Surgery
Multimodal Prehabilitation in Cancer Surgery
The PROPOSE RCT is a two-arm randomized controlled trial that will be conducted to test the efficacy of a personalized, multidisciplinary pre-operative prehabilitation program (preventive prehabilitation) to reduce serious…
- Trial name
- PROPOSE-RCT (NCT06788834)
- Testing
- Multimodal prehabilitation Program
- Where
- 9 sites in Italy
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Università Vita-Salute San Raffaele
Gestational Diabetes
Usability Study of the Sensors and eMOM GDM Application
The principal aim of the eMOM GDM-project is to evaluate the effect of the eMOM GDM -application and the integrated service concept model on maternal and neonatal outcomes.
- Trial name
- eMOMGDM (NCT03941652)
- Where
- Finland
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Acute Stroke, Upper Limb Motor Deficit
Effect of Early Tendon Vibrations on Upper Limb Motor Recovery After a Stroke
Strokes often induce a motor deficit. The resulting immobilization is in itself an aggravation factor since it worsens the motor deficit induced by the stroke itself.
- Trial name
- VIBRASTROKE (NCT07905625)
- Testing
- TVS rehabilitation sessions
- Where
- France
- Volunteers
- 54 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Obesity
Effects of High-intensity Exercise With Hypoxia and Taurine Supplementation on Metabolic and Mitochondrial Parameters
The prevalence of obesity in Brazil is one of the highest in Latin America. As an inflammatory disease, obesity needs to be treated, and one of the best interventions is exercise.
- Trial name
- NCT06579508
- Testing
- Cycle ergometer
- Where
- 2 sites in Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo