Clinical trials: Mouthwash
Periodontal Index, Pain
Efficacy of Zinc L-Carnosine Mouth Rinse
A clinical trial to assess the effect of a Zinc-L-Carnosine-based mouth rinse on periodontal tissues and pain after scaling and root planing
- Trial name
- NCT04430998
- Testing
- Zinc L-Carnosine, Chlorhexidine, Water
- Where
- Italy
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Milan
Streptococcus Mutans
Streptococcus Mutans Pathogenicity by Real-time Polymerase Chain Reaction (PCR) in High Caries Risk Patients
In patients with high caries risk, will the use of sage extract or chlorohexidine based mouthwashes have an effect on the percentage recovery of Streptococcus Mutans (SM) and its pathogenicity detected by Real-Time Polymerase…
- Trial name
- NCT04565912
- Testing
- Sage extract mouthwash, Chlorohexidine based mouthwash
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Cairo University
Postoperative Pain, Tonsillectomy
Ketamine Gargle for Pain After Pediatric Tonsillectomy
Post-tonsillectomy pain in children is a common and clinically significant problem that may lead to poor oral intake, dehydration, and delayed recovery.
- Conditions
- Postoperative Pain, Tonsillectomy, Adenotonsillectomy
- Trial name
- KET-TONSIL (NCT07558044)
- Testing
- Ketamine Hydrochloride in saline, Normal Saline (0.9% NaCl)
- Where
- Venezuela
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario de Caracas
COVID-19
The Role of Chlorhexidine in Minimizing the Viral Load Among COVID-19 Patients
Existing evidence confirmed that saliva and oral cavity to be a reservoir for SARS-CoV-2. In dental clinic aerosol-producing-procedures pose a significant risk for transmission of the infection .
- Trial name
- NCT04941131
- Testing
- Chlorhexidine digluconate, povidone iodine
- Where
- Saudi Arabia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Healthy
A Study of Virtually Supervised Mouth Rinses and Flossing
The purpose of this study is to evaluate the efficacy of brushing, flossing, and rinsing with essential oil mouth rinses; brushing and flossing; versus brushing and rinsing with essential oil mouth rinses; and brushing only for…
- Trial name
- NCT05600231
- Testing
- LISTERINE COOL MINT Antiseptic Mouthwash, LISTERINE COOL MINT ZERO Alcohol Mouthwash, Reach Unflavored Waxed Dental Floss
- Where
- United States
- Volunteers
- 284 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
Oral Mucositis
Hexetidine and Chlorobutanol for Lesions Due to Prostheses
Objectives: The study aimed at assessing the efficacy of a new mouthwash in treating oral lesions due to removable prostheses. Methods: The present prospective randomized clinical trial was performed on 44 patients.
- Trial name
- NCT01115049
- Testing
- chlorobutanol, hexetidine, Chlorhexidine
- Where
- Italy
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Federico II University
Bacterial Contamination
Effectiveness of Pre-Procedural CPC and Zinc Mouthwash in Reducing Dental Aerosols
This clinical trial evaluates the effectiveness of pre-procedural mouthwashes in reducing bacterial contamination in dental aerosols generated during ultrasonic scaling.
- Trial name
- NCT07880509
- Testing
- 0.09% CPC + Zinc Lactate Mouthwash, 0.2% Chlorhexidine Mouthwash, Water
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Cough
The Safety, Tolerability, PK and PD of GSK2339345 in Healthy Subjects
This is a First Time in Human (FTIH) study for the sodium channel inhibitor, GSK2339345. The study is split into two parts. Part A will assess the safety and tolerability of the new drug.
- Trial name
- FTIH (NCT01494636)
- Testing
- GSK2339345 (solution), GSK2339345 (nebulised), Lidocaine
- Where
- United Kingdom
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
The Retention of Iodine in Saliva Over the Time, The Comparison of Iodine in Saliva Between Gargle and Swab
Alternative Application Methods of Pre-procedural Povidone Iodine Mouthrinse
To compare the iodine remaining in saliva between gargle method and swab method
- Trial name
- NCT06272019
- Testing
- Iodine gargle
- Where
- Thailand
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Healthy
Biological Specimen Collection for Laboratory Methods Development and Training Purposes
This study will collect biological samples-buccal cells, blood sample, skin sample-to be used in developing and testing laboratory methods for measuring and analyzing genes.
- Trial name
- NCT00025831
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Plaque
A Clinical Study to Evaluate Effects of an Oral Rinse on Plaque and Gingivitis
Rinse contains an anti-plaque agent that helps prevent the accumulation of dental plaque associated with gingivitis.
- Trial name
- NCT03421145
- Testing
- 3M™ Oral Rinse, Vehicle Control Oral Rinse, PerioShield™ Oral Health Rinse
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Solventum US LLC
Plaque, Dental
Comparative Clinical Effects of Salvadora Persica Oral Rinse And A Phenolic Commercial Mouth Wash On Human Oral Health
ABSTRACT: OBJECTIVE: To compare the clinical effects of Salvadora persica (miswak) oral rinse and commercial Listerein mouth wash on oral health of socially deprived madrasa girls.
- Trial name
- RCT (NCT04713566)
- Testing
- oral rinces
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Multan Medical And Dental College
Dental Caries Prevention
Silver Nanoparticle vs Chlorhexidine Mouthwashes for Reducing Streptococcus Mutans and Improving Salivary pH in Children
Dental caries remains one of the most common chronic diseases in children, with Streptococcus mutans playing a major role in its development.
- Trial name
- SMILE (NCT07728409)
- Testing
- Silver nanoparticle mouthwash (10 ppm), Chlorhexidine mouthwash (0.2%)
- Where
- Egypt
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Assiut University
Gingivitis
A Clinical Trial to Test the Effect of Experimental Mouth Rinse on Gum Disease
Participants will be given special instructions about taking care of their teeth during the 18 hours before they come to the dentist's office for screening/baseline, 1 week, 2 weeks and 4 weeks.
- Trial name
- NCT02065414
- Testing
- Listerine Advance Gum Defense, Mouth rinse containing Chlorhexidine, Mouth rinse containing 5% Hydroalcohol
- Where
- United Kingdom
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
Halitosis
Effect of Mouth Rinses in Oral Malodor
Bad breath or halitosis is caused by specific gases originating from the mouth or the expired air. In most cases the pathology lies within the mouth and in this case receives the name pathologic halitosis of oral cause or oral…
- Trial name
- MR2012 (NCT01747226)
- Testing
- Fluoride rinse, Halita, Meridol Halitosis
- Where
- Belgium
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Caries
Effect of Enzyme-containing Mouth Rinse on Dental Biofilm in Patients With Fixed Orthodontic Appliances
Caries is a biofilm-mediated global public health problem causing health, social and economic consequences for individuals, communities and countries.
- Trial name
- NCT05033015
- Testing
- Mouth rinse
- Where
- Sweden
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Malmö University
Gingivitis, Dental Plaque
Antiplaque, Antigingivitis and Anti-inflammatory Effects of Myrrh Mouthwash
Myrrh-based mouthwash has the potential to be a suitable alternative to the gold standard chlorhexidine mouthwash for dental plaque and gingivitis reduction.
- Trial name
- NCT04723732
- Testing
- Myrrh mouthwash, Chlorhexidine mouthwash, Normal saline
- Where
- Saudi Arabia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University