Clinical trials: Movement; Disorder, Treatment-Induced
Infant Development, Hemiplegia
CIMT and taVNS for Hemiplegia in Infants
Newborns who are born premature or suffer brain injury at birth are at risk for motor problems that may cause weakness in reaching and grasping on one side of the body.
- Conditions
- Infant Development, Hemiplegia, Constraint Induced Movement Therapy
- Trial name
- NCT05101707
- Testing
- transcutaneous auricular vagus nerve stimulation, Constraint induced movement therapy
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Medical University of South Carolina
Erb's Palsy
Neuromuscular Electrical Stimulation With and Without Constraint Induced Movement Therapy in Erb's Palsy
Erb's Duchenne paralysis constitutes the single commonest form of brachial plexus injury, brachial plexus injury (BPI) is unfortunately a rather common injury in newborn children.
- Trial name
- NCT05723042
- Testing
- EMS with CIMT, EMS
- Where
- Pakistan
- Volunteers
- 22 people
- Sponsor
- Riphah International University
CVA (Cerebrovascular Accident), Stroke
Constraint-Induced Movement Therapy Plus Sensory Components After Stroke
Constraint-Induced Movement Therapy or CI Therapy is a form of treatment that systematically employs the application of selected behavioral techniques delivered in intensive treatment over consecutive day with the following…
- Conditions
- CVA (Cerebrovascular Accident), Stroke, Upper Extremity Paresis
- Trial name
- NCT05515237
- Testing
- Grade 2-5 CI Therapy + Sensory Components
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Alabama at Birmingham
Stroke, Hemispatial Neglect
mCIMT and Eye Patching for Neglect Rehabilitation Post Stroke: A Longitudinal Study of Separate and Combined Effects
The purpose of the current study is to evaluate relative efficacy of (1)modified constraint-induced movement therapy (mCIMT) combined with eye patching, (2)mCIMT, and (3) traditional rehabilitation on motor, attentional, and…
- Trial name
- NCT00253825
- Testing
- mCIMT combined with or without eye patching
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Stroke, Feedback, Psychological
Intervention Study of EMG Biofeedback Assisted Force Control to Treat Stroke Movement Disorder
Force generation and force level control are important neuromuscular control mechanism for successful execution of movement for our daily activities.
- Conditions
- Stroke, Feedback, Psychological, Motor Deficit
- Trial name
- NCT01962662
- Testing
- EMG biofeedback training, U/E exercise
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Cerebral Palsy
Feasibility of the Blended Care Pirate Group
Rationale: In 2010 Aarts developed the pirate group in which children received constrained induced movement therapy (constrained with a sling) followed by bilateral therapy.
- Trial name
- NCT06507631
- Testing
- Blended care pirate group
- Where
- Netherlands
- Volunteers
- 17 people
- Sponsor
- Sint Maartenskliniek
Hemiparesis, Cerebral Palsy
A Modified Constraint-Induced Movement Therapy Program in Rehabilitation of Arm Paresis in Children With Cerebral Palsy
The purpose of this study is to determine if a modified protocol of constraint-induced movement therapy (CIT) is effective in rehabilitation treatment of arm paresis in children with cerebral palsy.
- Trial name
- mCIT (NCT00473447)
- Testing
- Modified Constraint-induced movement therapy
- Volunteers
- 10 people
- Sponsor
- Universita di Verona
Parkinson Disease
Phase 1/2a Study of ANPD001 in Parkinson Disease
This clinical trial is designed to test the safety and tolerability of injecting ANPD001 cells that will mature into dopamine-producing cells into the brain of participants with Parkinson Disease.
- Trial name
- ASPIRO (NCT06344026)
- Testing
- ANPD001, Custom Device
- Where
- 9 sites in United States
- Volunteers
- 9 people
- Sponsor
- Aspen Neuroscience
Parkinson's Disease and Parkinsonism
Biomarker Validation Following Sargramostim Treatment in Parkinson's Disease
Investigators will evaluate the safety of a 48 week regimen of Leukine administered as a weight-based dose at 3 ug/kg/ day for 5 days followed by a 2-day holiday.
- Trial name
- NCT05677633
- Testing
- Sargramostim
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Nebraska
Cerebral Palsy (CP)
Constraint-induced Movement Therapy Combined With Functional Electrical Stimulation in Children With Cerebral Palsy
This randomized controlled trial aims to compare the effectiveness of Constraint-Induced Movement Therapy (CIMT) combined with Functional Electrical Stimulation (FES) versus CIMT alone in improving upper limb function, reducing…
- Trial name
- CIMT-FES-CP (NCT07587476)
- Testing
- Constraint-Induced Movement Therapy Combined with Functional Electrical Stimulation, Constraint-Induced Movement Therapy
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- Montiha Azeem
Stroke
Kinesiotaping and Constraint Induced Movement Therapy in Subacute Stroke
In stroke patients, the most common neurological deficits were motor impairment, loss of somatosensation, abnormal muscle tone, and impaired fractionated movement at affected limbs.
- Trial name
- NCT03682666
- Testing
- Kinesiotaping, modified Constraint Induced Movement Training
- Where
- Taiwan
- Volunteers
- 35 people
- Sponsor
- Chang Gung Memorial Hospital
Tardive Dyskinesia
Addressing Involuntary Movements in Tardive Dyskinesia
The purpose of this study is to determine whether fixed-doses of an investigational drug, SD-809 (deutetrabenazine), will reduce the severity of abnormal involuntary movements of tardive dyskinesia.
- Trial name
- AIM-TD (NCT02291861)
- Testing
- SD-809
- Where
- 106 sites in United States, Czechia and 4 more
- Volunteers
- 298 people
- Sponsor
- Auspex Pharmaceuticals, Inc.
Constraint Induced Movement Therapy, Task Oriented Training
Constraint-induced Movement Therapy Versus Task-oriented Training On Upper Extremity Function Post-Botox Injection in Stroke Patients
This study will be conducted to determine the impact of Constraint-Induced Movement Therapy versus Task-Oriented Training on upper extremity function post-Botox injection in stroke patients.
- Conditions
- Constraint Induced Movement Therapy, Task Oriented Training, Botox Injection, Upper Extremity Function
- Trial name
- NCT07057050
- Testing
- The designed physiotherapy program, The Botulinum toxin injection, Task oriented training
- Where
- Egypt
- Volunteers
- 51 people
- Sponsor
- Cairo University
Stroke
Effects of tDCS Combined With mCIMT or Mental Practice in Poststroke Patients
This study aims to evaluate systematically and controlled the effectiveness of mental practice techniques and modified constraint- induced movement therapy (mCIMT)in the treatment of post-stroke patients with motor deficit in the…
- Trial name
- NCT01879787
- Testing
- tDCS
- Where
- Brazil
- Volunteers
- 84 people
- Sponsor
- Universidade Federal de Pernambuco
Tardive Dyskinesia
Efficacy and Safety of MT-5199 in Subjects With Tardive Dyskinesia
The purpose of this study is to evaluate the efficacy and safety of MT-5199 administered once daily for the treatment of Tardive Dyskinesia (TD) symptoms.
- Trial name
- NCT03176771
- Testing
- MT-5199
- Where
- 82 sites in Japan
- Volunteers
- 256 people
- Sponsor
- Tanabe Pharma Corporation
Dyskinesia, Medication-induced
Levetiracetam in the Treatment of Neuroleptic-induced Tardive Dyskinesia
An 8-week study to examine safety and efficacy of levetiracetam in patients with neuroleptic-induced tardive dyskinesia
- Trial name
- NCT00175955
- Testing
- Levetiracetam
- Where
- 7 sites in Belgium, Bulgaria
- Volunteers
- 70 people
- Sponsor
- UCB Pharma
Stroke
Comparative Effects of Mirror Therapy, Proprioceptive Neuromuscular Facilitation, and Constraint-Induced Movement Therapy on Upper Limb Motor Recovery in Stroke Survivors: A Three-Arm Randomized Controlled Trial
This study aimed to compare the effects of these three interventions on upper limb motor recovery in stroke survivors. A three-arm randomized controlled trial was conducted in which eligible participants (N=90) with post-stroke…
- Trial name
- NCT07683130
- Testing
- mirror therapy, PNF, Constraint-induced movement therapy
- Where
- Pakistan
- Volunteers
- 90 people
- Sponsor
- Foundation of Medical Research and Laboratories, Pakistan
Cerebral Palsy Spastic Hemiplegic, Functionnal Neurological Disorder
Virtual Reality-Augmented Constraint-Induced Movement Therapy Versus Conventional Constraint-Induced Therapy for Upper Limb Rehabilitation in Children With Unilateral Cerebral Palsy.
Cerebral palsy (CP) causes persistent motor and postural impairments that can limit children's functional independence and participation.
- Conditions
- Cerebral Palsy Spastic Hemiplegic, Functionnal Neurological Disorder, Upper Limb Functions, Virtual Reality Based Therapy
- Trial name
- NCT07853937
- Testing
- Rehabilitation intervention
- Where
- Tunisia
- Volunteers
- 30 people
- Sponsor
- Faculty of Medicine, Sousse
PARKINSON DISEASE (Disorder), Cell Therapy
A Phase 1 Study of NCR201 in Parkinson's Disease Patients With Prior DBS
This is a Phase 1 clinical trial to evaluate the safety and tolerability of a new cell therapy called NCR201. The study will enroll adults with moderate-to-advanced primary Parkinson's disease who have previously undergone deep…
- Conditions
- PARKINSON DISEASE (Disorder), Cell Therapy, Human Induced Pluripotent Stem Cells, Deep Brain Stimulation
- Trial name
- NCR201-2004 (NCT07896187)
- Testing
- NCR201
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Nuwacell Biotechnologies Co., Ltd.
Stroke
Comparative Effects of PNF and mCIMT on Lower Limb Function in Patient With Stroke
Stroke, which is frequently characterized by weakness, poor balance, and decreased mobility that impede independence in everyday activities, has been identified as a major cause of long-term impairment globally.
- Trial name
- NCT07331714
- Testing
- PNF, mCIMT
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Riphah International University