Clinical trials: Movement Abnormalities
Parkinson's Disease
Genetic Polymorphism and Parkinson's Disease in Taiwanese
To observe and analyze the correlation between Single Nucleotide polymorphisms (SNPs) and the incidence of Parkinson's disease in Taiwanese.
- Trial name
- NCT01996878
- Where
- Taiwan
- Volunteers
- 334 people, healthy volunteers welcome
- Sponsor
- Changhua Christian Hospital
Motor Control, Parkinson Disease
Online Motor Control in People With Parkinson's Disease
This study aims to better understand how people with Parkinson's control reaching movements. Specifically, we are asking how these individuals respond to different environmental perturbations.
- Trial name
- NCT04616508
- Testing
- motor control assessment
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Tourette Syndrome, Tic Disorder
Sensorimotor and Psychosocial Trajectories in Adolescents With Tic Disorder
Individuals with tic disorders have lower quality of life, sensory and movement difficulties, and poorer mental, social, and physical health compared to the general population.
- Trial name
- NCT06576726
- Testing
- This study involves no intervention.
- Where
- United States
- Volunteers
- 351 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Alzheimer Disease, Huntington Disease
Dimebon (PF-01913539)-Digoxin Drug-Drug Interaction Study In Healthy Subjects
This study has been designed to confirm, in healthy subjects, the lack of a clinically important pharmacokinetic interaction between Dimebon, at the proposed maximum commercial dose of 20 mg TID (administered every 8 hours), and…
- Trial name
- NCT00831506
- Testing
- digoxin, dimebon
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pfizer
Parkinson's Disease, Parkinsonism
Parkinson's Families Project
One person in every 500 has Parkinson's and around 127,000 people are living with the condition in the UK. The aim of the study is to identify new genes that predispose or cause Parkinson's Disease or Parkinsonism.
- Trial name
- PFP (NCT02760108)
- Where
- 2 sites in United Kingdom
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University College, London
Alzheimer Disease, Parkinson Disease
Clinical Applicantion of Multi-Tracer PET/MR Imaging in Neurological Disorders/Disease
The goal of this clinical trial is to learn about the application of domestic PET/MR in major brain diseases. The main questions it aims to answer are: Overcome the bottleneck of early accurate diagnosis and treatment in major…
- Conditions
- Alzheimer Disease, Parkinson Disease, Epilepsy, Malignant Brain Tumor
- Trial name
- CAMIND (NCT06092125)
- Testing
- PET/MR
- Where
- China
- Volunteers
- 2,300 people, healthy volunteers welcome
- Sponsor
- Xuanwu Hospital, Beijing
Alzheimer Disease, Mild Cognitive Impairment
Clinical Feasibility of Speech Phenotyping for Remote Assessment of Neurodegenerative and Psychiatric Disorders
The primary objective of the study is to evaluate the feasibility of eliciting continuous narrative speech in different neurodegenerative and psychiatric indications, using remote, self-administered speech tasks, as measured by…
- Conditions
- Alzheimer Disease, Mild Cognitive Impairment, Dementia With Lewy Bodies, Dementia, Vascular
- Trial name
- RHAPSODY (NCT04939818)
- Where
- 2 sites in United Kingdom
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Novoic Limited
Parkinson Disease
Chinese DENOVO PD Registry
The main objective of this longitudinal, multi-center study is to explore the clinical characteristics of PD and confirm biomarkers for PD evolution or progression.
- Trial name
- NCT05767151
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Xiangya Hospital of Central South University
Dementia (Diagnosis), Alzheimer Dementia (AD)
Speech-Based Artificial Intelligence for Detection of Dementia in Danish Patients (DetectAI)
The goal of this observational study is to learn if an artificial intelligence (AI)-based speech analysis tool can identify which patients with memory problems need specialist evaluation at a memory clinic.
- Conditions
- Dementia (Diagnosis), Alzheimer Dementia (AD), Vascular Dementia (VaD), Lewy Body Dementia (LBD)
- Trial name
- DetectAI (NCT07200739)
- Testing
- Mini-mental State Examination, Addenbrooke's Cognitive Examination, Speech Task - Picture Description
- Where
- Denmark
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Speech Disorders, Voice Disorders
The Effect of Combined Speech and Music-therapy on the Speech Characteristics of People With Parkinson's Disease (PD)
Speech and voice disorders are observed in almost 90% of patients with PD during their course of illness. Reduced voice pitch inflections or monotone speech, reduced vocal loudness, prosody disorders, the imprecise articulation…
- Conditions
- Speech Disorders, Voice Disorders, Parkinson Disease
- Trial name
- NCT04966689
- Testing
- combined speech and music therapy, speech therapy, music therapy
- Where
- Iran
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Iran University of Medical Sciences
Parkinson's Disease (PD), Healthy Aging
Exoskeleton-Assisted Mobility in Aging and in Parkinson's Disease
This study will evaluate whether a wearable robotic exoskeleton can improve mobility, balance, and walking in healthy older adults and in individuals living with Parkinson's disease, populations at high risk of falls and mobility…
- Trial name
- NCT07567482
- Testing
- Exoskeleton
- Where
- Canada
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Centre intégré de santé et de services sociaux de l'Outaouais
Parkinson Disease
Quantification of Parkinson's Disease Patients as a Biomarker for Classification, Prediction and Response to Treatment
This is a three-armed open investigational study that aims to differentiate, quantify, and categorize abnormal eye movements and upper limbs movements in patients with Parkinson's disease.
- Trial name
- NCT06586320
- Testing
- 150% of their routine home dopaminergic medications dose right in the clinic, Evaluation of mathematical models
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Stardots AB
Parkinson Disease, Parkinsonism
Events Exposure as a Trigger of the Clinical Manifestations of Parkinson's Disease
Stress has been implicated as a trigger of many diseases, throughout different mechanisms. Potentially traumatic/stressful events exposure might be a factor that triggers subclinical disabilities related to PD becoming evident to…
- Trial name
- NCT05308485
- Testing
- Events exposure questionnaire
- Where
- Argentina
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia
Parkinson Disease
Virtual Reality in Parkinson Disease
Patients affected by Parkinson disease (PD) can benefit from rehabilitation although the evidences are scattered. In the last years there are increased evidences that virtual reality can improve functional outcome in Parkinson's…
- Trial name
- VRPark (NCT02807740)
- Testing
- Virtual reality, Conventional rehabilitation program
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Parkinson Disease, Fatigue
Lifestyle and Non-motor Symptom Management in Parkinson's Disease
Parkinson's Disease (PD) has generally been thought of as a movement disorder however other health-related symptoms, known as non-motor symptoms, are also very common.
- Trial name
- NCT04837976
- Testing
- Semi-structured interviews and a consensus workshops using nominal group techniques.
- Where
- United Kingdom
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Oxford Brookes University
Parkinson's Disease, Mild Cognitive Impairment
Longitudinal Study of Mild Cognitive Impairment in Parkinson's Disease
Parkinson's disease (PD) is known for its motor symptoms and affects more than 100,000 Canadians. However, PD patients also show cognitive deficits and neuropsychiatric problems that significantly impair their quality of life.
- Trial name
- PD-MCI (NCT02637089)
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Dementia With Lewy Bodies, Alzheimer Disease
DIagnostic Biomarkers and Symptoms in Patients With Alzheimer's Disease and Lewy bodY Dementia
This a study to improve diagnosis of dementia with Lewy bodies with RT-QuIC in different biospecimens.
- Conditions
- Dementia With Lewy Bodies, Alzheimer Disease, Mild Cognitive Impairment
- Trial name
- DISPLAY (NCT05768425)
- Testing
- Real-time quaking-induced conversion (RT-QuIC), Cognitive test, Motor examination
- Where
- Denmark
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Danish Dementia Research Centre
Parkinson's Disease
Pharmacokinetics of BIA 9-1067 in Subjects With Hepatic Impairment
The purpose of this study is to assess the pharmacokinetics (PK) of BIA 9-1067 in patients with moderate chronic hepatic impairment and in matched healthy subjects.
- Trial name
- NCT02101190
- Testing
- BIA 9-1067
- Where
- 3 sites in France, Russia
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Bial - Portela C S.A.
Alzheimer's Disease, Mild Cognitive Impairment
Retinal Imaging in Neurodegenerative Disease
This study aims to develop and evaluate biomarkers using non-invasive optical coherence tomography (OCT) and OCT angiography (OCTA) as well as ultra-widefield (UWF) fundus photography to assess the structure and function of the…
- Conditions
- Alzheimer's Disease, Mild Cognitive Impairment, Parkinson's Disease, Multiple Sclerosis
- Trial name
- NCT03233646
- Testing
- Retinal and Choroidal Imaging
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Duke University
Parkinson Disease, Stroke
Arousal Response Tool for Neurological Disease
The present study therefore aims at studying and evaluating the state of activation by psycho-physiological, behavioral, and subjective responses of individuals with Stroke and Parkinson's disease in contexts from the gradual…
- Conditions
- Parkinson Disease, Stroke, Healthy
- Trial name
- ART_ND (NCT03425877)
- Testing
- MS Band 2, Emotion Assessment, Single Task
- Where
- 2 sites in Italy
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- IRCCS San Camillo, Venezia, Italy
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.