Clinical trials: Movement Disorder
Breast Cancer, Kinesiophobia
Breast Cancer and Kinesiophobia and Physical Activity
Breast cancer is the most common type of cancer in women worldwide. A significant number of breast cancer survivors develop many complications.
- Trial name
- NCT05090098
- Testing
- None intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Pain Management, Injury Prevention
Can Micro-Doppler Predict Human Movement?
The analysis of human motion using radar has become an increasingly active topic of study due to the diverse applications offered by such an analysis (Lai et al., 2008; Fairchild \& Narayanan, 2016; Narayanan et al., 2014).
- Trial name
- NCT04468828
- Volunteers
- healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Dystonia, Dystonic Cerebral Palsy
Enhancing Sensorimotor Processing in Children With Dystonia
Dystonia is a severely disabling movement disorder with no cure, in which people suffer painful muscle spasms causing twisting movements and abnormal postures. There are many causes, including genetic conditions and brain injury.
- Conditions
- Dystonia, Dystonic Cerebral Palsy, Dystonia, Secondary, Dystonia, Primary
- Trial name
- NCT05612464
- Testing
- No intervention
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- King's College London
Parkinson's Disease, Parkinsonism
Exploratory Study Using Nanotechnology to Detect Biomarkers of Parkinson's Disease From Exhaled Breath
Parkinson's disease is diagnosed clinically, because biomarkers that may help in diagnosis and differential diagnosis are not yet available.
- Trial name
- NCT01246336
- Testing
- collection of exhaled breath
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Laser, Intrusion
Histological Change of The Dentinal-Pulp Complex and Root Resorption
The purpose of the study is evaluate the histological changes of the dentinal-pulp complex and root resorption in maxillary premolars with intrusive orthodontic movement under a low power laser effects.
- Conditions
- Laser, Intrusion, Histology, Resorption
- Trial name
- NCT01642693
- Testing
- Low power laser in teeth after intrusive movement, Simulated laser in teeth with intrusive movements
- Where
- Colombia
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Universidad de Antioquia
Multiple System Atrophy (MSA), Parkinson's Disease (PD)
A Study to Evaluate Satety, Tolerability, Biodistribution, Radiation Dosimetry, and Pharmacokinetics of SST001 in Healthy Volunteers, Patients With PD and Patients With MSA
The non-randomized, open-label phase I study aims to evaluate the safety, tolerability, biodistribution, radiation dosimetry, and pharmacokinetics of SST001 in healthy volunteers, patients with MSA and patients with PD.
- Trial name
- NCT07604116
- Testing
- SST001
- Where
- 2 sites in China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Synusight Biotech (Shanghai) Co., Ltd.
Malocclusion
The Use of Clear Aligners With Movement Enhancement Techniques
The purpose of this study is to use clear aligners to measure tooth movement and length of treatment.
- Trial name
- NCT02087163
- Testing
- Movement Enhancement Technique, Clear Aligner
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Align Technology, Inc.
Parkinson's Disease, Depression
Validation of the Hebrew Version of the Montreal Affective Voices.
Today, no non-verbal auditory stimuli that assess mental processing are available in Israel. The goal of this study is to make available a validated set of auditory stimuli in Israel.
- Trial name
- NCT01512732
- Where
- Israel
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Parkinson Disease, Healthy
Neurofeedback Training for PD
The goal of this clinical trial is to test neurofeedback training in both people with Parkinson's disease and healthy control. The main questions it aims to answer are: To demonstrate that EEG based or STN LFP based neurofeedback…
- Trial name
- NCT05987865
- Testing
- Neurofeedback training
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Parkinson's Disease, HIV Infections
Using Heavy Water to Study Cell Dynamics in Parkinson's Disease
This pilot study will assess the feasibility of using heavy water as a safe 'tracer' for biomarker studies of diseases of the brain and spinal cord, that, together, are also called the central nervous system (CNS).
- Trial name
- NCT00990379
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Salena Killion
Angelman Syndrome
Angelman Syndrome Video Assessment (ASVA) Source Material Study
This is a longitudinal, observational, nonrandomized, fully remote study enrolling approximately 55 participant-caregiver dyads.
- Trial name
- ASVA SMS (NCT05637697)
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- The Emmes Company, LLC
Parkinson Disease
Molecular Epidemiology of Parkinson's Disease
The aim of this research is to discover genes which modify risk for Parkinson's disease. The study includes 800 patients with Parkinson's disease, and their estimated 1,222 available siblings.
- Trial name
- NCT00042107
- Where
- United States
- Volunteers
- 2,022 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Dystonia, Focal Dystonia
Brain Changes in Blepharospasm
This study will examine the role of certain areas of the brain in blepharospasm, a type of dystonia (abnormality of movement and muscle tone) that causes unwanted or uncontrollable blinking or closing of the eyelids.
- Conditions
- Dystonia, Focal Dystonia, Cerebellar Disease
- Trial name
- NCT00487383
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Parkinson Disease, Multiple System Atrophy
Facilitating Diagnostics and Prognostics of Parkinsonian Syndromes Using Neuroimaging
The goals of this study are: 1) to identify biomarkers using neuroimaging that are associated with progression rate using statistical methods, and 2) to identify biomarkers that are associated with the differential diagnosis of…
- Conditions
- Parkinson Disease, Multiple System Atrophy, Progressive Supranuclear Palsy
- Trial name
- NCT03872102
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Subluxation
Simulated vs Genuine Manual Chiropractic Adjustments
Our primary aim with this trial is to measure participant blinding following two simulated/sham or genuine/real high velocity, low amplitude (HVLA) manual chiropractic adjustments to assess if participants are able to identify…
- Trial name
- SHA (NCT06931600)
- Testing
- Chiropractic adjustment
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Life University
Impulsive Behavior, Impulse Disorders
Clinical Response of Impulsivity After Brain Stimulation in Parkinson's Disease
The objective of this prospective observational cohort study is to answer the following clinically important questions: 1. In patients with a pre-operative history of ICBs, what is the likelihood of improvement or deterioration…
- Conditions
- Impulsive Behavior, Impulse Disorders, Gambling, Pathological, Eating, Binge
- Trial name
- CRIPS (NCT04811807)
- Testing
- Subthalamic Nucleaus Deep brain stimulation
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- King's College London
Parkinson, Multiple Sclerosis
Driving Performance in Parkinson's Disease and Multiple Sclerosis Using a Driving Simulator
This prospective observational study investigates whether driving performance measured in a standardized driving simulator differs between people with Parkinson's disease, people with multiple sclerosis, and healthy drivers.
- Trial name
- NeuroSimDrive (NCT07809828)
- Testing
- Standardized Driving Simulator Assessment
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital Olomouc
Parkinson's Disease
Biomarker Discovery in Parkinson's Disease
There are approximately one million Americans who live with Parkinson's disease with 50,000 new cases per year and this rate is expected to rise with an aging population.
- Trial name
- DISCOVERY-PD (NCT02016092)
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- The Parkinson's Institute
Parkinson's Disease
to Evaluate the Safety, Tolerability and Pharmacokinetics of Four Formulations of LY03009 in Healthy Volunteers
The purpose of this study is to Evaluate the Safety, Tolerability and Pharmacokinetics of Four Formulations of LY03009 in Healthy Volunteers.
- Trial name
- NCT04593511
- Testing
- LY03009 F1, LY03009 F2, LY03009 F3
- Where
- Australia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Luye Pharma Group Ltd.
Depression, Stress, Psychological
Rural Dementia Caregiver Project
Rural caregivers face challenges of geographic isolation and lower health care access and quality. Many rural dementia caregivers experience serious health consequences due to caregiving responsibilities that can limit their…
- Conditions
- Depression, Stress, Psychological, Self Efficacy, Loneliness
- Trial name
- NCT04428112
- Testing
- Building Better Caregivers Workshop, Attention Control
- Where
- United States
- Volunteers
- 418 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
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