Clinical trials: Movement Disorder
Parkinson's Disease
Genetic Polymorphism and Parkinson's Disease in Taiwanese
To observe and analyze the correlation between Single Nucleotide polymorphisms (SNPs) and the incidence of Parkinson's disease in Taiwanese.
- Trial name
- NCT01996878
- Where
- Taiwan
- Volunteers
- 334 people, healthy volunteers welcome
- Sponsor
- Changhua Christian Hospital
Cerebellar Disease, Dementia
Effects of Brain Stimulation on Learning and Reasoning
Imaging studies of the brain have revealed the different areas involved in the processes of learning and reasoning. However, the specific role these regions play in these processes, or if stimulating these areas can improve these…
- Conditions
- Cerebellar Disease, Dementia, Healthy, Parkinson's Disease
- Trial name
- NCT00001776
- Testing
- Cadwell Rapid Rate Magnetic Stimulator
- Where
- United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Huntington's Disease
Escalating Dose Study in Healthy Volunteers With SEN0014196
This is a trial in healthy volunteers to study the safety, tolerability and pharmacokinetics of single and multiple escalating doses of SEN0014196.
- Trial name
- NCT01521832
- Testing
- SEN0014196
- Where
- United Kingdom
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Siena Biotech S.p.A.
Parkinson Disease
Distribution of Non-Motor Symptoms in Idiopathic Parkinson's Disease and Secondary Parkinsonism
BACKGROUND: Non-Motor Symptoms (NMS) are frequent in patients with Idiopathic Parkinson's Disease (IPD). Clinical expressions, postulated pathophysiological mechanisms and responsiveness to antiparkinson medication represent…
- Trial name
- NCT03432338
- Testing
- inquiries
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Örjan Skogar
Cerebral Palsy
Piloting Movement-to-Music With Arm-based Sprint-Intensity Interval Training Among Children With Physical Disabilities
This study is investigating the potential effects of a high-intensity home-exercise program among children with cerebral palsy. The program includes rhythmic movements to music that are adapted for wheelchair uses and…
- Trial name
- NCT05619211
- Testing
- Sprint-Intensity Interval Training with Telecoaching
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Schizophrenia, Bipolar
Bipolar and Schizophrenia Consortium for Parsing Intermediate Phenotypes
Briefly, this multisite study is designed to identify endophenotypes (i.e., heritable biomarkers) associated with either schizophrenia or bipolar disorder alone, or both together.
- Trial name
- NCT00666432
- Testing
- This is an observational study model that is family based
- Where
- 6 sites in United States
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Parkinson's Disease
Striatal and Extra-striatal Mechanisms of Falling in Parkinson's Disease
This research study will evaluate functions of memory, thinking, eye movements and walking and how these relate to the measurement of certain chemicals (acetylcholine and dopamine) in the brain using an imaging procedure called…
- Trial name
- NCT00736671
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Dementia, Vascular, Dementia
Systematic Care for Informal Caregivers of Dementia Patients: An Efficient Approach?
The objective is to ascertain the potential efficiency of a systematic care programme for caregivers of dementia patients. The research questions are: What are the costs and benefits of the Systematic Care Programme - Dementia…
- Conditions
- Dementia, Vascular, Dementia, Alzheimer Disease, Lewy Body Disease
- Trial name
- NCT00147693
- Testing
- Diagnosis of caregivers' problems, Professional service: treatment of problems by counseling or practical support
- Where
- Netherlands
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Frontotemporal Lobar Degeneration (FTLD), Progressive Supranuclear Palsy (PSP)
ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)
ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD) represents the formalized integration of ARTFL (U54 NS092089; funded through 2019) and LEFFTDS (U01 AG045390; funded through 2019) as a single North American…
- Conditions
- Frontotemporal Lobar Degeneration (FTLD), Progressive Supranuclear Palsy (PSP), Corticobasal Degeneration (CBD), Behavioral Variant Frontotemporal Dementia (bvFTD)
- Trial name
- NCT04363684
- Where
- 26 sites in United States, Canada
- Volunteers
- 2,100 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Spinal Cord Injuries
Neural Facilitation of Movements in People With SCI
Spinal cord injury leads to long-lasting paralysis and impairment. Re-enabling movement of paralyzed areas is challenging and more information is needed about neurological recovery.
- Trial name
- NCT05354206
- Testing
- Electrophysiology assessment - corticospinal tract, Electrophysiology assessment - reticulospinal tract, Training with some stimulation
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Aging, Parkinson Disease
Beam Walking Across the Lifespan for Falls Prediction
Background: Dynamic balance keeps the vertical projection of the center of mass within the base of support while the center of mass moves. The age-related decrease in dynamic balance is a risk factor for falls.
- Conditions
- Aging, Parkinson Disease, Stroke, Dementia
- Trial name
- BEAM (NCT03532984)
- Testing
- Beam test to predict falls
- Where
- 5 sites in Brazil, Germany and 3 more
- Volunteers
- 432 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Parkinson's Disease
Investigation of Road-crossing Safety Before and After Training Between Parkinson Disease Pedestrians and Older Pedestrians
As society ages, a large amount of human factors related research has been carried out into the subject of the safety of the elderly in their daily lives.
- Trial name
- NCT01727687
- Testing
- behavioral training for crossing road
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Parkinson's Disease
Safety and Tolerability Study of Cogane™ in Healthy Volunteers and Parkinson's Disease Patients
Phytopharm plc is developing Cogane™ which is a new medicine for the treatment of Parkinson's disease (PD). The purpose of the study is to find out if Cogane is safe and well tolerated in both healthy volunteers and Parkinson's…
- Trial name
- NCT00875316
- Testing
- Cogane™ (PYM50028)
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Phytopharm
Moderate and Severe Crowding in Lower Dental Arch
Evaluation of Effects of Bracket's Slot System on the Quantity and Quality of Teeth Movements During Orthodontic Leveling and Alignment Stage
Evaluation of effect of bracket slot system on the quality and quantity of tooth movement during leveling and alignment stage
- Trial name
- NCT05537506
- Testing
- Bracket slot 0.018, Bracket slot 0.022
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Stroke, Multiple Sclerosis
New Interactive Sensor-home-based Hand Training to Improve Dexterity
Primary objective of this study is to explore the impact of a 3-week upper limb hand function training in patients with PD, MS or stroke. The benefits on hand function of this training program will be evaluated.
- Conditions
- Stroke, Multiple Sclerosis, Parkinson Disease
- Trial name
- NCT06062693
- Testing
- smart sensor egg training
- Where
- Switzerland
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Luzerner Kantonsspital
Post-traumatic Stress Disorder (PTSD), Trauma and Stress Related Disorders
Grappling With Trauma: Brazilian Jiu-Jitsu for First Responders
This study explores whether participating in an 8-week Brazilian Jiu-Jitsu (BJJ) program is linked to changes in trauma-related symptoms among first responders.
- Conditions
- Post-traumatic Stress Disorder (PTSD), Trauma and Stress Related Disorders, Occupational Stress, Emotional Regulation Difficulties
- Trial name
- CAM-GRIP (NCT07783516)
- Testing
- Brazilian Jiu-Jitsu Program
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Sam Houston State University
Stroke
Control of Degrees of Freedom Post-stroke for the Recovery of the Upper Limb
The study's methodology will be a single-blind, multicenter, parallel-group randomized controlled trial (RCT). The sample consists of stroke patients (supratentorial ischemic and hemorrhagic stroke of anterior territory) between…
- Trial name
- DoF_UL_S (NCT05371444)
- Testing
- Training with restriction of the DoF, Training without restriction of the DoF
- Where
- Chile
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Chile
Functional Movement Disorder
Study of Sensory Attenuation in Functional Movement Disorders
Functional movement disorders (FMD) are conditions where people experience unusual movements or difficulties with walking, not caused by a specific brain or nerve injury but related to how the brain controls movements.
- Trial name
- NCT06872788
- Where
- Canada
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Exercise, Gait
Rhythmically Entrained Exercise in Community-Dwelling Older Adults
Researchers at the University of North Carolina at Greensboro conduct a single-arm intervention trial to investigate the efficacy of a music-based group exercise program for community-dwelling older adults.
- Conditions
- Exercise, Gait, Cognitive Decline, Caregiver Burden
- Trial name
- REECO (NCT05462977)
- Testing
- Group exercise program
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Greensboro
Parkinson´s Disease, REM Sleep Behavior Disorder (iRBD)
The Swedish BioFINDER Sleep Study
BioFINDER-Sleep study was established in 2021 and will include patients with early Parkinson´s disease (PD) and persons with iRBD to provide essential insights into the underlying mechanisms of the progressive neurodegenerative…
- Conditions
- Parkinson´s Disease, REM Sleep Behavior Disorder (iRBD), Lewy Body Disease, Synucleinopathy
- Trial name
- NCT07533799
- Testing
- Dopamine transporter PET scan with [18F]FE-PE2I, Magnetic resonance imaging (MRI), [123I] MIBG scintigraphy of the heart
- Where
- Sweden
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Skane University Hospital
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