Clinical trials: Movement Disorders, Functional
Parkinson's Disease
Development of a Face Valid Executive Functioning Task
The purpose of this study is to develop a task to measure executive thinking skills that can be performed in a laboratory setting, but has clear parallels to the thinking demands of real life situations, and can be administered…
- Trial name
- MedTask (NCT00918112)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Stroke, Rehabilitation
Augmented-reality Based Mirror Therapy in Stroke Rehabilitation
In the proposed study, the investigators assumed that mirror therapy combined with augmented reality technology will provide a better treatment effects than traditional mirror therapy for the patients with unilateral stroke.
- Conditions
- Stroke, Rehabilitation, Technology, Mirror Movement Therapy
- Trial name
- NCT05580744
- Testing
- Traditional occupational therapy, Mirror therapy using a mirror box, Augmented reality-based mirror therapy
- Where
- Taiwan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Parkinson's Disease, Physical Activity
Effect of High Intensity Interval Training on Mechanisms of Neuroplasticity in Parkinson's Disease Patients
There are experimental evidences of the important role of high intensity physical exercise in Parkinson's disease (PD) treatment, that induces similar effects to pharmacotherapy.
- Conditions
- Parkinson's Disease, Physical Activity, Neurorehabilitation, Neuroplasticity
- Trial name
- NCT04204551
- Testing
- high-intensity interval training (HIIT), conventional physical therapy
- Where
- Poland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Wroclaw University of Health and Sport Sciences
Joint Loose Bodies
Different Methods of Physical Therapy for Stroke
It is estimated that worldwide, about 15 million people are affected by vascular accident (CVA) per year, and in Brazil, the stroke is a major cause of death and disability, generating too much economic and social impact by…
- Trial name
- NCT02932631
- Testing
- THERAPY CONTROL AND MOVEMENT OF INDUCTION
- Where
- Brazil
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Universidade Metodista de Piracicaba
Parkinson Disease
Subthalamic Nucleus Connectivity in Parkinson's Disease With Ultra-high Field Magnetic Resonance Imaging
The purpose of this study is to investigate the segregation of the subthalamic nucleus into its motor and non-motor regions in patients with Parkinson's disease and healthy controls with the aid of ultra-high field magnetic…
- Trial name
- NCT01981577
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Parkinson Disease
Robotic Assessments of Hand Function in Patients With Parkinson's Disease
It has been shown that patients with Parkinson's disease (PD) have impaired kinaesthesia and haptic perception of the upper limbs.
- Trial name
- RHK Parkinson (NCT05245955)
- Testing
- Assessments of the hand sensory function with the ReHapticKnob
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Parkinson's Disease
Psychiatric and Cognitive Manifestations of Parkinson's Disease
Parkinson's Disease (PD) is often thought of as affecting movement only. In fact, most patients also experience psychiatric and cognitive symptoms, sometimes from the disease itself, and sometimes as a side-effect of PD…
- Trial name
- NCT00360633
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Parkinson Disease
Mapping Levodopa Effects on Cortico-basal Ganglia Circuit Function in Parkinson's Disease
Levodopa-induced dyskinesia (LID) in Parkinson's disease (PD) are involuntary movements caused by long-term treatment with dopaminergic replacement therapy (levodopa). During the cause of PD, most patients develop LID.
- Trial name
- Dyn-fMRI-PD (NCT06240624)
- Testing
- No intervention
- Where
- Denmark
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Danish Research Centre for Magnetic Resonance
Patellofemoral Pain
Bilateral Knee Pain and Dry Needling
This project will evaluate the effects of bilateral knee pain and dry needling (DN) on laterality recognition, movement and muscle function.
- Trial name
- NCT05976269
- Testing
- Dry needling
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Parkinson's Disease, REM Sleep Behavior Disorder
Exploration of the Reward System by Functional MRI in Parkinson's Disease Patients With and Without REM Sleep Behavior Disorder
Up to 60% of Parkinson's Disease (PD) patients suffer from REM sleep behavior disorder (RBD), a parasomnia. This disorder is thought to be related to a dysfunction of limbic system and brainstem.
- Trial name
- MP-TCSP-IRMf (NCT02824341)
- Testing
- fMRI
- Where
- France
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Sports Physical Therapy, Physical Functional Performance
Outdoor Horseback Riding and Its Effects on Muscle Strength, Balance, Sleep, and Movement
This study aims to investigate the effects of regular outdoor horseback riding on lower extremity muscle strength, core stabilization, balance, functional movement capacity, sleep quality, and overall well-being in healthy…
- Conditions
- Sports Physical Therapy, Physical Functional Performance, Horseback Riding
- Trial name
- NCT07286864
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Istinye University
Parkinson's Disease
Investigating the Microstructural and Functional Alterations of Brain in Parkinson's Disease Patients
The objective of this protocol is to investigate the microstructural alterations and monoaminergic function in Parkinson's disease patients with impulse control disorders and cognitive impairment by multimodal MRI and 18F-DTBZ…
- Trial name
- NCT02599753
- Testing
- 18-FDTBZ
- Where
- Taiwan
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Parkinson's Disease
A Study in Healthy Male Volunteers to Investigate a New Drug for the Treatment of Parkinson's Disease
The main purpose of the study is to identify the best dose of V81444 to use in future trials in patients with Parkinson's disease.
- Trial name
- NCT02764892
- Testing
- V81444
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Vernalis (R&D) Ltd
Parkinson Disease
Mapping Functional Networks of Brain Activity (Brain Network Activation, BNA) Based on Analysis of Evoked Response Potential (ERP) Signals for Healthy Controls Evoked Response Potential (ERP) Signals for Healthy Controls and Patients With Parkinson Disease
A cornerstone in PD research is the investigation of neurophysiological changes as potential biomarkers that could help in tracking disease progression and response to therapies.
- Trial name
- NCT02149498
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Dr. Oren Cohen
Stroke, Healthy
Use of Transcranial Direct Current Stimulation (tDCS) Coupled With Constraint Induced Movement Therapy in Stroke Patient
The purpose of this study is to determine whether noninvasive brain stimulation associated with motor learning offers an additional benefit than motor learning alone in patients with stroke.
- Trial name
- tdcs (NCT01143649)
- Testing
- transcranial direct current stimulation (tDCS), constraint induced movement therapy (CIMT), transcranial alternating current stimulation (tACS)
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Spaulding Rehabilitation Hospital
Healthy
Use of Real-Time Functional Magnetic Resonance Imaging Neurofeedback to Improve Motor Function in Cerebellar Ataxia
This project will study the feasibility of motor rehabilitation in people with cerebellar ataxia using real-time functional magnetic resonance imaging neurofeedback (rt-fMRI NF) in conjunction with motor imagery.
- Trial name
- fMRI (NCT05436249)
- Testing
- Neurofeedback treatment, At-home therapy
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Scapular Dyskinesis, Cervicalgia
Global Postural Reeducation and Segmental Exercises in Patients With Scapular Dyskinesis and Cervicalgia
The purpose of this study is to assess the effectiveness of global postural reeducation relative to segmental exercises in the treatment of scapular dyskinesis with cervicalgia.
- Trial name
- NCT01568840
- Testing
- Global Postural Reeducation Group, Segmental Exercises Group
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Irmandade da Santa Casa de Misericordia de Sao Paulo
Seizure Disorder, Seizure Disorder, Post Traumatic
Neuroimaging Biomarker for Seizures
This multi-site study will examine patients with epilepsy (ES) following head injury [i.e., posttraumatic epilepsy (PTE)] and posttraumatic psychogenic Non-epileptic seizures (PNES) and will compare them to patients with…
- Conditions
- Seizure Disorder, Seizure Disorder, Post Traumatic, Traumatic Brain Injury, Non-Epileptic Seizure
- Trial name
- NIBMSZS (NCT03441867)
- Testing
- Cognitive Behavioral Therapy for Seizures, Standard Medical Care
- Where
- 3 sites in United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Providence VA Medical Center
Essential Tremor
Functional Outcomes of Awake vs. Asleep Deep Brain Stimulation (DBS) for Essential Tremor
Recently, there has been increasing interest in performing DBS under general anesthesia, where the stimulated targets are located anatomically (i.e.
- Trial name
- NCT02418858
- Testing
- Deep Brain Stimulation surgery
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- St. Joseph's Hospital and Medical Center, Phoenix
Parkinson Disease
BIG for Life: a Pilot Study
This research study will aim to evaluate BIG for LIFE as a group exercise program, and determine whether three time a week exercise sessions with heart rate monitoring is beneficial to maintain or improve physical function…
- Trial name
- NCT04090476
- Testing
- Exercise
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University