Clinical trials: Movement Disorders, Functional
Tenosynovitis
Mobilization With Movement Versus Joint-Specific Manipulation in De Quervain's Tenosynovitis
A comparative study on the effectiveness of mobilization with movement (MWM) versus joint-specific manipulation (JSM) in patients with De Quervain's tenosynovitis typically aims to assess how each technique impacts pain relief…
- Trial name
- NCT06918158
- Testing
- Mobilization with Movement, Joint Specific Manipulation
- Where
- Pakistan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Parkinson's Disease
A Study Assessing Change in Sense of Smell After Rasagiline Use in Parkinson's Patients
A decrease or loss of the sense of smell is very common in patients with Parkinson's Disease even in the earliest stages of the disease.
- Trial name
- PD-SOAR (NCT01007630)
- Testing
- Rasagiline
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- The Parkinson's Institute
Parkinson's Disease
DBS Frequency on Swallowing Function in Parkinson's Disease
The stimulation frequency has been found to affect the axial symptoms of freezing of gait (FOG) and speech in advanced Parkinson's disease (PD) patients with subthalamic nucleus deep brain stimulation (STN DBS), with the…
- Trial name
- NCT01935011
- Testing
- PD, DBS
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Chicago
Cerebral Cortex Dysfunction
Brain Function in Primary Lateral Sclerosis and Amyotrophic Lateral Sclerosis
This study will test whether primary lateral sclerosis (PLS) and amyotrophic lateral sclerosis (ALS) affect parts of the brain responsible for thinking, planning, memory and emotion.
- Trial name
- NCT00334516
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Conversion Disorder
Efficacy of Dorso-lateral Prefrontal Cortex Stimulation by tDCS in Motor Conversion Disorder Patients
Conversion disorder refers to impaired voluntary motor or sensory functions that are not compatible with a well-known neurological condition.
- Trial name
- CONVERSTIM (NCT04097184)
- Testing
- Neurostimulation with non-implanted electrodes
- Where
- 8 sites in France
- Volunteers
- 96 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Parkinson Disease
Use of a Non-Invasive Brainstem Neuromodulation Device to Improve Neurovascular Status in Parkinson's Disease
This study is a single-site, double-blinded, randomized clinical trial designed to elucidate mechanism(s) of action for symptomatic benefits observed in Parkinson's disease (PD)
- Trial name
- NCT04598828
- Testing
- Non-invasive brainstem stimulation
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Wake Forest University Health Sciences
Parkinson Disease, Parkinsonian Disorders
Effect of Undenatured Cysteine-Rich Whey Protein Isolate (HMS 90®) in Patients With Parkinson's Disease
This is a double-blind, placebo-controlled, Phase IV trial , comparing HMS 90® versus placebo (soy protein) as add-on (adjuvant) therapy in subjects with idiopathic Parkinson's Disease.
- Conditions
- Parkinson Disease, Parkinsonian Disorders, Basal Ganglia Diseases, Brain Diseases
- Trial name
- NCT01662414
- Testing
- Whey protein, Soy protein
- Where
- Thailand
- Volunteers
- 38 people
- Sponsor
- Chulalongkorn University
Parkinson Disease(PD)
Cycling and Treadmill With Dual Task for Parkinson's Disease Improvement
Motor impairment in lower extremities is common in individuals with Parkinson disease (PD). Development sensitive test for early motor deviations is important.
- Trial name
- NCT06355947
- Testing
- Cognitive cycling training, Cognitive treadmill training
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Chang Gung University
Spinal Amyotrophy
SMAdult - Monitoring of Movement on Spinal Muscular Atrophy
Spinal muscular atrophy (SMA) is a rare neuromuscular disease causing progressive muscle weakness related to degeneration of motor neurons.
- Trial name
- SMAdult (NCT07894185)
- Testing
- wearable sensors
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Universitaire de Liege
Parkinson Disease
Neocortical Microarchitecture of Executive Function
This study is being done to the determine the ability and utility of using the Neuropixels probes in the human brain. A Neuropixels probe will be inserted into and removed from the brain of awake human patients who are undergoing…
- Trial name
- NCT06778135
- Testing
- Temporary implatation of large-scale intracranial electrode., brain electrode
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Colorado, Denver
Cerebral Palsy
A Trial Comparing Two Methods of CIMT in the Hemiplegic Child
Cerebral palsy remains a major cause of lifelong disability affecting approximately 2 per 1,000 children. Of those about 30% have hemiplegic cerebral palsy (HPC),a unilateral impairment, which can often lead to major difficulties…
- Trial name
- HCPCIMT (NCT01770678)
- Testing
- Constraint Induced Movement Therapy
- Volunteers
- 62 people
- Sponsor
- University of Birmingham
Parkinson Disease, Mild Cognitive Impairment
Financial Abilities in Neurological Diseases. Development of a Telerehabilitation Program: FINAGE
Financial Abilities (FA) are a set of capacities that allow a person to independently manage her/his financial affairs in a manner consistent with personal self-interests and values.
- Conditions
- Parkinson Disease, Mild Cognitive Impairment, Stroke
- Trial name
- FINAGE (NCT05826548)
- Testing
- Telerehabilitation group, Conventioanl treatment group
- Where
- Italy
- Volunteers
- 140 people
- Sponsor
- IRCCS San Camillo, Venezia, Italy
Total Hip Replacement, Hip Dislocation
How Spinopelvic Movements Affect Hip Function After Total Hip Arthroplasty
Our study aims to evaluate the effect of spinopelvic movement on hip functions in individuals who have undergone total hip arthroplasty (THA).
- Conditions
- Total Hip Replacement, Hip Dislocation, Hip Osteoarthritis
- Trial name
- THA (NCT06711042)
- Testing
- functional tests and radiographic analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ordu University
Glenohumeral Internal Rotation Deficit (GIRD)
Effect of Joint Mobilization and Movement Control Exercises on Shoulder Pain and Function in Fast Bowlers (RCT)
The goal of this clinical trial is to determine combined effects of the Kinetic control for shoulder on pain, range, and function among fast bowlers.
- Trial name
- RCT (NCT07229274)
- Testing
- Kinetic control for shoulder internal rotation with mobilization with movement, stretches, strengthening and mobilization with movement
- Where
- 2 sites in Pakistan
- Volunteers
- 50 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Parkinson Disease
Incentive Spirometer and Inspiratory Muscle Trainer
Patients suffering from parkinsonism have respiratory function abnormalities. This study compared the effects of incentive spirometer and inspiratory muscle trainer on pulmonary functions in patients with parkinsonism.
- Trial name
- NCT05201742
- Testing
- Inspiratory muscle training, Incentive Spirometry
- Where
- Saudi Arabia
- Volunteers
- 18 people
- Sponsor
- King Saud University
Parkinson Disease
Acute Effects of AMPS on Cardiovascular, Functional Capacity and Postural Control in Patients With Parkinson's Disease
Considering that Parkinson's Disease (PD) can significantly compromise functional mobility and cardiovascular system in patients with PD, therapies aimed at improving these aspects, mainly by non-pharmacological and non-invasive…
- Trial name
- NCT05456282
- Testing
- Automated mechanical peripheral stimulation
- Where
- Chile
- Volunteers
- 40 people
- Sponsor
- Universidad Católica del Maule
Intellectual Disability, Rubinstein-Taybi Syndrome
Functional Tests to Resolve Unsolved Rare Diseases. Rares.
Rares diseases are a heterogeneous group of conditions which need important tools for diagnosis. The use of high-throughput sequencing is able to diagnose half of the patients.
- Conditions
- Intellectual Disability, Rubinstein-Taybi Syndrome, Cystic Fibrosis, Congenital Heart Defect
- Trial name
- RID (NCT05696912)
- Testing
- Ex-vivo approach concerning 25 patients, In-vitro approach concerning 25 patients
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Bordeaux
Somatoform Disorders, Globus Hystericus
Treatment of Globus Sensations With Psychotherapy
The purpose of this study is to determine whether psychotherapy (based on exposure techniques) is effective in the treatment of functional somatic symptoms (FSS)/Somatoform Disorders (as exemplified here in subjects with globus…
- Trial name
- NCT01590992
- Testing
- Exposure-based psychotherapy for somatic symptoms, Relaxation therapy
- Where
- Switzerland
- Volunteers
- 175 people
- Sponsor
- University Hospital, Basel, Switzerland
Globus Pharyngeus
Prevalence of Salivary Hypofunction in Patients With Globus Pharyngeus
It is well known that 'globus sensation in throat' is caused by the chronic irritation and inflammation of oral, pharyngeal, or laryngeal mucosa, such as laryngopharyngeal reflux and chronic postnasal drip.
- Trial name
- NCT00381771
- Testing
- Conservative management for xerostomia
- Where
- South Korea
- Volunteers
- 340 people
- Sponsor
- Samsung Medical Center
Neurodegenerative Diseases
Exploring the Recovery Function of Sleep in Neurodegeneration
The overall objective of this study is to identify the best approach for assessing the recovery function of sleep in neurodegenerative diseases associated with abnormal protein aggregation with regard to the conception of future…
- Trial name
- RFSN (NCT05402488)
- Testing
- Auditory stimulation
- Where
- Switzerland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Zurich