Clinical trials: Movement Disorders, Functional
Esophageal Cancer, Esophagectomy
Oesophagectomy and Chest Wall and Respiratory Function
Open surgery for esophageal cancer commonly involves large incisions in the chest, associated with a high rate of pulmonary complications (30-50%).
- Conditions
- Esophageal Cancer, Esophagectomy, Respiratory Function Loss
- Trial name
- NCT03835273
- Testing
- 3D motion capture system, Incentive spirometry, Questionnaires
- Where
- United Kingdom
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Parkinson Disease
Speech and Voice Outcomes Following HD-tDCS Over the Left SMA
Pharmaceutical and neurosurgical treatments reliably ameliorate the cardinal motor symptoms in PD but, they often yield inconsistent outcomes for speech and voice disorders, with some studies showing exacerbation of pre-treatment…
- Trial name
- NCT06245070
- Testing
- Active transcranial direct current stimulation
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Louisiana State University and A&M College
Parkinson's Disease
Use of Noninvasive Brain Stimulation in Parkinson's Disease
The purpose of this research is to determine whether repetitive sessions of transcranial direct current stimulation (tDCS) to the prefrontal cortex can enhance the cognitive, affective and motor functioning of those with…
- Trial name
- NCT01113086
- Testing
- Transcranial direct current stimulation
- Where
- 2 sites in United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Spaulding Rehabilitation Hospital
Parkinson's Disease
Tryptophan Depletion in PD Patients Treated With STN DBS
The purpose of this study is to assess the effect of tryptophan depletion on mood and behavior in Parkinson's disease (PD) patients treated with deep brain stimulation (DBS) of the subthalamic nucleus (STN).
- Trial name
- NCT02632279
- Testing
- Tryptophan (TRP) depletion, Stimulator ON, Stimulator OFF
- Where
- Netherlands
- Volunteers
- 7 people
- Sponsor
- Maastricht University Medical Center
Parkinson Disease
Resistance Training in Patients With Parkinson's Disease.
This is a controlled trial to assess the effects of resistance training on bradykinesia and physical function in patients with Parkinson's Disease.
- Trial name
- NCT02447146
- Testing
- Resistance Training, Lectures on the disease
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Brasilia
Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1
Baby Detect : Genomic Newborn Screening
Newborn screening (NBS) is a global initiative of systematic testing at birth to identify babies with pre-defined severe but treatable conditions.
- Conditions
- Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1, Phosphoglucomutase 1 Deficiency, Maturity Onset Diabetes of the Young
- Trial name
- BabyDetect (NCT05687474)
- Where
- Belgium
- Volunteers
- 6,824 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Liege
Erb's Palsy
Neuromuscular Electrical Stimulation With and Without Constraint Induced Movement Therapy in Erb's Palsy
Erb's Duchenne paralysis constitutes the single commonest form of brachial plexus injury, brachial plexus injury (BPI) is unfortunately a rather common injury in newborn children.
- Trial name
- NCT05723042
- Testing
- EMS with CIMT, EMS
- Where
- Pakistan
- Volunteers
- 22 people
- Sponsor
- Riphah International University
Cerebral Palsy, Hand Function
Constraint-induced Movement Therapy and Hand Arm Bimanual Training in Children With Hemiplegic Cerebral Palsy (CP)
The combination of the constraint-induced movement therapy (CIMT) method as a complement to hand arm bimanual training (HABIT) will improve the frequency and quality of cooperative hand use and function in children with…
- Trial name
- NCT01078766
- Testing
- CIMT+HABIT
- Volunteers
- 9 people
- Sponsor
- Alyn Pediatric & Adolescent Rehabilitation Hospital
Idiopathic Parkinson's Disease, Multiple Sclerosis
Online Cognitive Training in PD, MS and Depressed Patients Treated With Electroconvulsive Therapy
In Parkinson's disease, Multiple Sclerosis and depressed patients treated with electroconvulsive therapy, cognitive dysfunction is prevalent. However, treatment of these dysfunctions is in its infancy.
- Conditions
- Idiopathic Parkinson's Disease, Multiple Sclerosis, Elderly Post Electric Convulsive Therapy
- Trial name
- NCT02525367
- Testing
- Online cognitive training, Active control condition
- Where
- Netherlands
- Volunteers
- 28 people
- Sponsor
- Amsterdam UMC, location VUmc
Knee Osteoarthritis
The Benefit of Functional Movement Control for Patients With Knee Osteoarthritis
The study purpose is to explore the effect of functional movement control for patients who have stage II or III degenerative knee joint disease and also physical inactive.
- Trial name
- NCT03431298
- Testing
- Aerobic exercise & movement control, Aerobic exercise
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Yang Ming Chiao Tung University
Parkinson Disease
Effects of Home Rehabilitation of Balance Based on Functional Exercises in People With Parkinson's Disease
Balance rehabilitation programs in people with Parkinson's disease (PD) that include functional exercises, i.e. using tasks of daily living in training, show improvements in variables related to balance and gait.
- Trial name
- balanceHOME (NCT04963894)
- Testing
- Home functional balance physiotherapy, Conventional physiotherapy
- Where
- 2 sites in Spain
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Foot Injuries, Posterior Tibial Tendon Dysfunction
The CurePPaC Study - Analysing Non-surgical Treatment Strategies to Cure Pes Planovalgus Associated Complaints
Pes planovalgus, also called flat foot, is a common foot deformity characterized by a flattening of the foot's longitudinal arch and is accompanied by a dysfunction of the posterior tibial tendon ("posterior tibial tendon…
- Trial name
- NCT01839669
- Testing
- Foot Orthoses Only, Foot Orthoses and Eccentric Exercise
- Where
- 6 sites in Switzerland
- Volunteers
- 7 people
- Sponsor
- Bern University of Applied Sciences
Parkinson Disease
Cognitive-motor Training in Parkinson Disease
Literature reviews showed the cognitive-motor training that combines cognitive tasks may enhance cognitive functions more effectively than individual interventions.
- Trial name
- NCT06588439
- Testing
- Cognitive-motor training, Conventional physiotherapy
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- National Yang Ming Chiao Tung University
Parkinson Disease (PD), Cognition
Short Term Effects of a Multimodal Intervention With RGM on Cognition in People With Parkinson's Disease.
The goal of this clinical trial is to learn if the Ronnie Gardiner Method (RGM) works to improve cognitive functions in adults with Parkinson's disease (early to mid-stage).
- Conditions
- Parkinson Disease (PD), Cognition, Quality of Life, Functional Mobility
- Trial name
- NCT07863219
- Testing
- Ronnie Gardiner Method
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- University Ghent
Parkinson Disease
The Effect of Whole Body Vibration in Individuals With Parkinson's Disease
Previous studies reported that whole body vibration has the potential impact on balance and walking abilities in individuals with Parkinson's disease; however, the inconsistent treatment protocols and different experimental…
- Trial name
- NCT03777501
- Testing
- non-random whole body vibration, occupational therapy
- Where
- Taiwan
- Volunteers
- 34 people
- Sponsor
- Chang Gung University
PARKINSON DISEASE (Disorder), Proprioceptive Neuromuscular Facilitation
The Effect of Proprioceptive Neuromuscular Facilitation on Trunk Mobility, Gait, Fear of Falling, and Quality of Life in Individuals Diagnosed With Parkinson's Disease
Parkinson's disease (PD) is a neurological disease that includes four main findings: resting tremor, bradykinesia, postural instability, and rigidity, in addition to many motor and non-motor symptoms .
- Conditions
- PARKINSON DISEASE (Disorder), Proprioceptive Neuromuscular Facilitation, Fear of Falling, Gait Performance
- Trial name
- NCT07327645
- Testing
- Proprioceptive Neuromuscular Facilitation (PNF)
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Pamukkale University
Globus, Deglutition Disorders
ACHAT-STUDY, Alternative Treatment of Chronic Globus Sensations
Globus sensations are associated with gastroesophageal reflux disease as well as the presence of a gastric inlet patch. No controlled trial exists on whether ablation of the cervical heterotopic mucosa may lead to improvement of…
- Trial name
- NCT00439439
- Testing
- Beamer Ablation (Argon Plasma Coagulation)
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Technical University of Munich
Cerebral Palsy Spastic Hemiplegic
Investigation of the Effect of Constraint Induced Movement Therapy Applied to the Lower Extremity on Lower Extremity Functions in Individuals With Unilateral Cerebral Palsy
Lower extremity constraint induced movement therapy has been applied to individuals with multiple sclerosis, stroke, subacute and chronic hemiparesis in recent years and positive results have been reported.
- Trial name
- NCT06753812
- Testing
- constraint induced movement therapy, Control (Standard treatment)
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Abant Izzet Baysal University
Muscular Dystrophy, Duchenne, Orthotic Devices
The Effect of a Muscle-mimicking, Fabric-type Shoulder Orthosis on Functional Movements of the Upper Limb in Patients With Neuromuscular Disorder
The goal of this clinical trial is to investigate the effect of a muscle-mimicking, fabric-type shoulder orthosis on functional movements of the upper limb in patients with neuromuscular disorder.
- Conditions
- Muscular Dystrophy, Duchenne, Orthotic Devices, Upper Extremity, Neuromuscular Diseases (NMD)
- Trial name
- NCT06363357
- Testing
- Shoulder orthosis
- Where
- South Korea
- Volunteers
- 8 people
- Sponsor
- Seoul National University Hospital
Parkinson Disease
Quantitative Imaging of Brain Glymphatic Function in Humans
Recent immunological and physiological studies have provided evidence in support of a central nervous system (CNS) lymphatic drainage system in vertebrate animals, and preliminary evidence has suggested that a similar system…
- Trial name
- NCT04768101
- Testing
- [11C]-PIB
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center