Clinical trials: Movement Disorders, Functional
Parkinson Disease, Pain
Transcranial Photobiomodulation as a Therapy for Patients With Parkinson's Disease: Relationship Between Pain and Brain Functional Connectivity (FBM)
Parkinson's disease is a progressive and degenerative neurological movement disorder that affects thousands of people. The disease is characterized by presenting motor and non-motor symptoms, as the disease progresses, it becomes…
- Conditions
- Parkinson Disease, Pain, Photobiomodulation
- Trial name
- FBM (NCT05959772)
- Testing
- Photobiomodulation
- Where
- 2 sites in Brazil
- Volunteers
- 82 people
- Sponsor
- University of Sao Paulo
Functional Neurological Disorder, Motor Symptoms
Investigating the Neurophysiology of the Motor System and the Feasibility of Vagus Nerve Stimulation in Functional Neurological Disorder (FND)
This clinical study will test if adding a non-invasive stimulation of the vagus nerve through the ear during physiotherapy brings an improvement to FND (Functional Neurological Disorder) patients with motor symptoms.
- Trial name
- TMS-VNS (NCT07710677)
- Testing
- Vagial Nerve Stimulation (VNS) active stimulation
- Where
- Switzerland
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Fribourg
Psychogenic Nonepileptic Seizures (PNES)
Cognitive Rehabilitation for Veterans With PNES
Psychogenic nonepileptic seizures (PNES) reflect a subtype of functional neurological disorder (FND) that is common and extremely disabling in Veterans.
- Trial name
- CRVWP (NCT07316543)
- Testing
- Cognitive Rehabilitation And Functional Treatment (CRAFT)
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- VA Office of Research and Development
Stroke
Effectiveness of Modified Constraint Induced Movement Therapy to Improve Lower Extremity Function in the Acute and Subacute Stroke Patients by Providing 1 Hour of Intense Massed Practice in the Form of Shaping or Task Practice
This is a prospective randomized control trial of patients with unilateral impairment of the lower extremity after stroke. Patients will be randomized to intervention group and control group.
- Trial name
- NCT03604081
- Testing
- CIMT, Conventional Physical Therapy
- Where
- United States
- Sponsor
- NYU Langone Health
Parkinson Disease, Balance; Distorted
Validity Reliability of The Dubousset Functional Test in Parkinson Disease
In order to achieve collaborative patient-centered rehabilitation in Parkinson's disease, detailed evaluation of walking and balance in evaluating the perceived difficulty in daily life is important to evaluate the progression of…
- Conditions
- Parkinson Disease, Balance; Distorted, Fall, Gait Disorders, Neurologic
- Trial name
- NCT04622657
- Testing
- dubousset functional test
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Kırıkkale University
Parkinson's Disease
Effects of Yoga on Parkinson's Disease
The study's purpose is to assess the effect of yoga on measures of oxidative stress (i.e. reduction-oxidation [redox] status); motor function; and psychosocial well-being, and the feasibility and acceptability of implementing a…
- Trial name
- HYPD (NCT02509611)
- Testing
- Hatha yoga
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Minnesota
Spinal Cord Injuries, Autonomic Dysreflexia
Spinal Cord Stimulation and Autonomic Response in People With SCI.
Despite being studied less than half as frequently, autonomic dysfunction is a greater priority than walking again in spinal cord injury.
- Conditions
- Spinal Cord Injuries, Autonomic Dysreflexia, Orthostatic Hypotension, Dysautonomic
- Trial name
- NCT03924388
- Testing
- Epidural spinal cord stimulation, Trnascutaneous electrical spinal cord stimulation.
- Where
- 2 sites in Canada
- Volunteers
- 46 people
- Sponsor
- University of Calgary
Parkinson Disease
Investigation of the Psychometric Properties of the Squares Test in Measuring Hand Function in Parkinson's Disease
The first aim of the present study was to investigate reliability, validity and responsiveness to the minimal clinically important difference, which is defined as the smallest change in score corresponding to clinically…
- Trial name
- NCT03580486
- Testing
- The squares test
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Gazi University
Spinal Cord Injuries (SCI), Orthostatic Hypotension, Dysautonomic
Cardiovascular Function and Response to Stimulation Within the First Year After Spinal Cord Injury
The study aims to explore how cardiovascular function changes in the first year after a spinal cord injury, and to see how different treatments, like spinal stimulation through the skin (transcutaneous spinal stimulation), affect…
- Conditions
- Spinal Cord Injuries (SCI), Orthostatic Hypotension, Dysautonomic, Cardiovascular, Transcutaneous Spinal Stimulation
- Trial name
- NCT06841198
- Testing
- spinal cord transcutaneous stimulation, Ice testing
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Parkinson's Disease
Interactive Stepping Exercise on Balance and Cognitive Function
The objective of this study is to investigate the effects of interactive stepping exercise on balance and cognitive function in individuals with PD.
- Trial name
- NCT04494906
- Testing
- Interactive stepping exercise, Square stepping exercise
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Yang Ming Chiao Tung University
Irritable Bowel Syndrome, Healthy
Remote Study of an Electronic Means to Characterize Bowel Movements in Adult Populations
A remote study to find out if a mobile phone application (HealthMode Stool) can serve as a useful tool to track and characterize daily bowel movements.
- Trial name
- NCT04182048
- Where
- United States
- Volunteers
- 843 people, healthy volunteers welcome
- Sponsor
- HealthMode Inc.
Duchenne Muscular Dystrophy (DMD)
Research on the Relationship Between Scoliosis, Pain, Quality of Life, and Trunk Muscle Compensation Patterns Among Patients with Duchenne Muscular Dystrophy.
Objective: The objective of this observational study is to evaluate and quantify trunk muscle compensatory movement patterns in patients with Duchenne Muscular Dystrophy (DMD) using computer vision technology.
- Trial name
- NCT06755138
- Testing
- Observational Assessment
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Essential Tremor
Functional Brain Network Changes in Patients Undergoing Deep Brain Stimulation for Essential Tremor
The purpose of this study is to collect electrophysiological data related to functional brain network changes in patients undergoing deep brain stimulation for the treatment of essential tremor.
- Trial name
- TRaNCE (NCT06293638)
- Testing
- Alcohol, Alprazolam, Cold Therapy
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Parkinson Disease, Camptocormia
The Effect of Spinal Mobilization on Respiratory Parameters in Parkinson's Disease Patients
Parkinson's patients suffer from respiratory distress for different reasons. It is thought that physiotherapy methods that have an indirect effect on the diaphragm can improve respiratory functions.
- Conditions
- Parkinson Disease, Camptocormia, Restrictive Lung Disease
- Trial name
- NCT04941326
- Testing
- Diaphragmatic stimulation treatment with PNF techniques, Costal mobilization, Breathing exercises
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Abant Izzet Baysal University
Stroke
Brunnstrom Movement Therapy Versus Mirror Therapy on Hand Function in Stroke
This study will be randomized clinical trial. Non Probability consecutive sampling technique will be used. Data will be collected from patients having stroke by using tools i.e Fugl-Meyer assessment: wrist and hand (FMA- WH) and…
- Trial name
- NCT05392543
- Testing
- Brunnstrom movement therapy., Mirror Therapy
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Riphah International University
Stroke,Hemiplegia
Effects of Modified Constraint-Induced Movement Therapy and Mirror Therapy in Hemiplegic Stroke
The purpose of this study is to investigate and compare the effects of Modified Constraint-Induced Movement Therapy (mCIMT) and Mirror Therapy (MT) on upper extremity motor functions, activity participation, and independence in…
- Trial name
- NCT07668349
- Testing
- Mirror Therapy, Modified Constraint-Induced Movement Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people
- Sponsor
- Nisa Kiliç Koçak
Parkinson' Disease
Effects of Physical Exercise Combined With Transcranial Direct Current Stimulation in Parkinson's Disease
A controlled, blinded, and randomized clinical study will be carried out in a large sample of people with Parkinson's disease, where the combined effects of physical exercise and transcranial direct curren stimlation (tDCS) on…
- Trial name
- ExtDCSPARK (NCT07524400)
- Testing
- real tDCS and exercise, Exercise
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universidad Rey Juan Carlos
Essential Tremor, Dystonia
Magnetic Resonance (MR) Guided Functional Ultrasound-Neurosurgery for Movement Disorders
The aim of this study is to asses the efficacy and the clinical safety of the transcranial magnetic resonance guided high intensity focused ultrasound system ExAblate 4000, InSightec Ltd.
- Conditions
- Essential Tremor, Dystonia, Parkinson's Disease
- Trial name
- NCT01698450
- Testing
- Non-invasive intervention with focused ultrasound (ExAblate 4000)
- Where
- Switzerland
- Volunteers
- 10 people
- Sponsor
- University Children's Hospital, Zurich
Psychogenic Movement Disorders, Non-epileptic Seizures
Psychiatric Correlates of Psychogenic Movement Disorder and Non-Epileptic Seizure
This study will explore how the mind and the brain work to cause movement symptoms or seizures in people who do not have a recognized neurological or medical disorder.
- Trial name
- NCT00255411
- Where
- United States
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Functional Neurological Disorder
Integrated Treatment in FND (Functional Neurological Disorders)
The project will investigate the effectiveness of patient-centered integrated treatment. The correlations between physiotherapy indices, non-invasive brain stimulation, connectivity and psychological support will be analyzed.
- Trial name
- FND (NCT04310670)
- Testing
- Psychotherapy, Physiotherapy, Non-Invasive Brain Stimulation (NIBS)
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Neuromed IRCCS